|
US3126375A
(en)
|
|
1964-03-24 |
|
Chioacyl |
|
US2789118A
(en)
|
1956-03-30 |
1957-04-16 |
American Cyanamid Co |
16-alpha oxy-belta1, 4-pregnadienes
|
|
US2990401A
(en)
|
1958-06-18 |
1961-06-27 |
American Cyanamid Co |
11-substituted 16alpha, 17alpha-substituted methylenedioxy steroids
|
|
US3048581A
(en)
|
1960-04-25 |
1962-08-07 |
Olin Mathieson |
Acetals and ketals of 16, 17-dihydroxy steroids
|
|
US3749712A
(en)
|
1970-09-25 |
1973-07-31 |
Sigma Tau Ind Farmaceuti |
Triamcinolone acetonide esters and process for their preparation
|
|
SE378109B
(pt)
|
1972-05-19 |
1975-08-18 |
Bofors Ab |
|
|
US3996359A
(en)
|
1972-05-19 |
1976-12-07 |
Ab Bofors |
Novel stereoisomeric component A of stereoisomeric mixtures of 2'-unsymmetrical 16,17-methylenedioxy steroid 21-acylates, compositions thereof, and method of treating therewith
|
|
SE378110B
(pt)
|
1972-05-19 |
1975-08-18 |
Bofors Ab |
|
|
US4319039A
(en)
|
1979-06-15 |
1982-03-09 |
Merck & Co., Inc. |
Preparation of ammonium salt of hypocholesteremic fermentation product
|
|
US4294926A
(en)
|
1979-06-15 |
1981-10-13 |
Merck & Co., Inc. |
Hypocholesteremic fermentation products and process of preparation
|
|
US4231938A
(en)
|
1979-06-15 |
1980-11-04 |
Merck & Co., Inc. |
Hypocholesteremic fermentation products and process of preparation
|
|
US4444784A
(en)
|
1980-08-05 |
1984-04-24 |
Merck & Co., Inc. |
Antihypercholesterolemic compounds
|
|
MX7065E
(es)
|
1980-06-06 |
1987-04-10 |
Sankyo Co |
Un procedimiento microbiologico para preparar derivados de ml-236b
|
|
JPS5889191A
(ja)
|
1981-11-20 |
1983-05-27 |
Sankyo Co Ltd |
３−ヒドロキシ−ｍｌ−２３６ｂ誘導体の製造法
|
|
US5354772A
(en)
|
1982-11-22 |
1994-10-11 |
Sandoz Pharm. Corp. |
Indole analogs of mevalonolactone and derivatives thereof
|
|
US4911165A
(en)
|
1983-01-12 |
1990-03-27 |
Ethicon, Inc. |
Pliabilized polypropylene surgical filaments
|
|
US5032617A
(en)
|
1985-05-03 |
1991-07-16 |
Sri International |
Substituted benzamide radiosensitizers
|
|
US5215738A
(en)
|
1985-05-03 |
1993-06-01 |
Sri International |
Benzamide and nicotinamide radiosensitizers
|
|
US5041653A
(en)
|
1985-05-03 |
1991-08-20 |
Sri International |
Substituted benzamide radiosensitizers
|
|
US4681893A
(en)
|
1986-05-30 |
1987-07-21 |
Warner-Lambert Company |
Trans-6-[2-(3- or 4-carboxamido-substituted pyrrol-1-yl)alkyl]-4-hydroxypyran-2-one inhibitors of cholesterol synthesis
|
|
US4885314A
(en)
|
1987-06-29 |
1989-12-05 |
Merck & Co., Inc. |
Novel HMG-CoA reductase inhibitors
|
|
US4782084A
(en)
|
1987-06-29 |
1988-11-01 |
Merck & Co., Inc. |
HMG-COA reductase inhibitors
|
|
US4820850A
(en)
|
1987-07-10 |
1989-04-11 |
Merck & Co., Inc. |
Process for α-C-alkylation of the 8-acyl group on mevinolin and analogs thereof
|
|
US5030447A
(en)
|
1988-03-31 |
1991-07-09 |
E. R. Squibb & Sons, Inc. |
Pharmaceutical compositions having good stability
|
|
US5180589A
(en)
|
1988-03-31 |
1993-01-19 |
E. R. Squibb & Sons, Inc. |
Pravastatin pharmaceuatical compositions having good stability
|
|
US4916239A
(en)
|
1988-07-19 |
1990-04-10 |
Merck & Co., Inc. |
Process for the lactonization of mevinic acids and analogs thereof
|
|
EP0360390A1
(en)
|
1988-07-25 |
1990-03-28 |
Glaxo Group Limited |
Spirolactam derivatives
|
|
US5118853A
(en)
|
1988-10-13 |
1992-06-02 |
Sandoz Ltd. |
Processes for the synthesis of 3-disubstituted aminoacroleins
|
|
US5290946A
(en)
|
1988-10-13 |
1994-03-01 |
Sandoz Ltd. |
Processes for the synthesis of 3-(substituted indolyl-2-yl)propenaldehydes
|
|
MX18467A
(es)
|
1988-11-23 |
1993-07-01 |
Pfizer |
Agentes terapeuticos de quinuclidinas
|
|
US4929437A
(en)
|
1989-02-02 |
1990-05-29 |
Merck & Co., Inc. |
Coenzyme Q10 with HMG-CoA reductase inhibitors
|
|
US5164372A
(en)
|
1989-04-28 |
1992-11-17 |
Fujisawa Pharmaceutical Company, Ltd. |
Peptide compounds having substance p antagonism, processes for preparation thereof and pharmaceutical composition comprising the same
|
|
US5189164A
(en)
|
1989-05-22 |
1993-02-23 |
Sandoz Ltd. |
Processes for the synthesis of syn-(E)-3,5-dihydroxy-7-substituted hept-6-enoic and heptanoic acids and derivatives and intermediates thereof
|
|
FI94339C
(fi)
|
1989-07-21 |
1995-08-25 |
Warner Lambert Co |
Menetelmä farmaseuttisesti käyttökelpoisen /R-(R*,R*)/-2-(4-fluorifenyyli)- , -dihydroksi-5-(1-metyylietyyli)-3-fenyyli-4-/(fenyyliamino)karbonyyli/-1H-pyrroli-1-heptaanihapon ja sen farmaseuttisesti hyväksyttävien suolojen valmistamiseksi
|
|
PH27357A
(en)
|
1989-09-22 |
1993-06-21 |
Fujisawa Pharmaceutical Co |
Pyrazole derivatives and pharmaceutical compositions comprising the same
|
|
IE903957A1
(en)
|
1989-11-06 |
1991-05-08 |
Sanofi Sa |
Aromatic amine compounds, their method of preparation and¹pharmaceutical compositions in which they are present
|
|
FR2654726B1
(fr)
|
1989-11-23 |
1992-02-14 |
Rhone Poulenc Sante |
Nouveaux derives de l'isoindolone et leur preparation.
|
|
FR2654725B1
(fr)
|
1989-11-23 |
1992-02-14 |
Rhone Poulenc Sante |
Nouveaux derives de l'isoindolone, leur preparation et les compositions pharmaceutiques qui les contiennent.
|
|
GB8929070D0
(en)
|
1989-12-22 |
1990-02-28 |
Fujisawa Pharmaceutical Co |
Peptide compounds,processes for preparation thereof and pharmaceutical composition comprising the same
|
|
UA41251C2
(uk)
|
1990-01-04 |
2001-09-17 |
Пфайзер, Інк. |
Гідровані азотвмісні гетероциклічні сполуки, похідні піперидину, фармацевтична композиція та спосіб пригнічення активності речовини р в організмі
|
|
US5232929A
(en)
|
1990-11-28 |
1993-08-03 |
Pfizer Inc. |
3-aminopiperidine derivatives and related nitrogen containing heterocycles and pharmaceutical compositions and use
|
|
US5321032A
(en)
|
1990-02-15 |
1994-06-14 |
Fujisawa Pharmaceutical Co., Ltd. |
Peptide compounds and pharmaceutical compositions thereof
|
|
US5420245A
(en)
|
1990-04-18 |
1995-05-30 |
Board Of Regents, The University Of Texas |
Tetrapeptide-based inhibitors of farnesyl transferase
|
|
GB9011833D0
(en)
|
1990-05-25 |
1990-07-18 |
Collins Mary K L |
Inhibition of viral infection
|
|
DE69105131T2
(de)
|
1990-06-01 |
1995-03-23 |
Pfizer |
3-amino-2-arylchinuclidine, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen.
|
|
CA2086434C
(en)
|
1990-07-23 |
1998-09-22 |
John A. Lowe, Iii |
Quinuclidine derivatives
|
|
HUT68667A
(en)
|
1990-09-28 |
1995-07-28 |
Pfizer |
Fused ring analogs of nitrogen containing nonaromatic heterocycles
|
|
GB9023116D0
(en)
|
1990-10-24 |
1990-12-05 |
Fujisawa Pharmaceutical Co |
Peptide compounds,processes for preparation thereof and pharmaceutical composition comprising the same
|
|
DE69114117T2
(de)
|
1990-12-21 |
1996-03-21 |
Fujisawa Pharmaceutical Co |
Neue Verwendung von Peptidderivat.
|
|
JPH0733385B2
(ja)
|
1991-01-10 |
1995-04-12 |
フアイザー・インコーポレイテツド |
物質ｐの拮抗薬としてのｎ−アルキルキヌクリジニウム塩
|
|
ATE154354T1
(de)
|
1991-02-11 |
1997-06-15 |
Merck Sharp & Dohme |
Azabicyclische verbindungen, diese enthaltende pharmazeutische zubereitungen und ihre therapeutische verwendung
|
|
DE69200921T2
(de)
|
1991-03-01 |
1995-05-04 |
Pfizer |
1-azabicyclo[3.2.2]nonan-3-aminderivate.
|
|
US5747469A
(en)
|
1991-03-06 |
1998-05-05 |
Board Of Regents, The University Of Texas System |
Methods and compositions comprising DNA damaging agents and p53
|
|
EP0581777A1
(en)
|
1991-03-26 |
1994-02-09 |
Pfizer Inc. |
Stereoselective preparation of substituted piperidines
|
|
FR2677361A1
(fr)
|
1991-06-04 |
1992-12-11 |
Adir |
Nouveaux peptides et pseudopeptides, derives de tachykinines, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
|
|
FR2676053B1
(fr)
|
1991-05-03 |
1993-08-27 |
Sanofi Elf |
Nouveaux composes dialkylenepiperidino et leurs enantiomeres, procede pour leur preparation et compositions pharmaceutiques les contenant.
|
|
FR2676055B1
(fr)
|
1991-05-03 |
1993-09-03 |
Sanofi Elf |
Composes polycycliques amines et leurs enantiomeres, procede pour leur preparation et compositions pharmaceutiques les contenant.
|
|
FR2676446B1
(fr)
|
1991-05-17 |
1993-08-06 |
Rhone Poulenc Rorer Sa |
Nouveaux derives du thiopyranopyrrole, leur preparation et les compositions pharmaceutiques qui les contiennent.
|
|
FR2676443B1
(fr)
|
1991-05-17 |
1993-08-06 |
Rhone Poulenc Rorer Sa |
Nouveaux derives de perhydroisoindole et leur preparation.
|
|
FR2676442B1
(fr)
|
1991-05-17 |
1993-08-06 |
Rhone Poulenc Rorer Sa |
Nouveau derives de perhydroisoindole, leur preparation et les compositions pharmaceutiques qui les contiennent.
|
|
FR2676447B1
(fr)
|
1991-05-17 |
1993-08-06 |
Rhone Poulenc Rorer Sa |
Nouveaux derives du thiopyranopyrrole et leur preparation.
|
|
CA2109415C
(en)
|
1991-05-22 |
1998-12-29 |
Fumitaka Ito |
Substituted 3-aminoquinuclidines
|
|
US5292726A
(en)
|
1991-05-22 |
1994-03-08 |
Merck & Co., Inc. |
N,N-diacylpiperazines
|
|
ES2084361T3
(es)
|
1991-05-31 |
1996-05-01 |
Pfizer |
Derivados de quinuclidina.
|
|
GB9113219D0
(en)
|
1991-06-19 |
1991-08-07 |
Fujisawa Pharmaceutical Co |
Peptide compound,processes for preparation thereof and pharmaceutical composition comprising the same
|
|
EP0589924B1
(en)
|
1991-06-20 |
1996-09-04 |
Pfizer Inc. |
Fluoroalkoxybenzylamino derivatives of nitrogen containing heterocycles
|
|
TW202432B
(pt)
|
1991-06-21 |
1993-03-21 |
Pfizer |
|
|
US5288730A
(en)
|
1991-06-24 |
1994-02-22 |
Merck Sharp & Dohme Limited |
Azabicyclic compounds, pharmaceutical compositions containing them and their use in therapy
|
|
EP0536817A1
(en)
|
1991-07-05 |
1993-04-14 |
MERCK SHARP & DOHME LTD. |
Azabicyclic compounds as tachykinin antagonists
|
|
US5629347A
(en)
|
1991-07-05 |
1997-05-13 |
Merck Sharp & Dohme Ltd. |
Aromatic compounds, pharmaceutical compositions containing them and their use in therapy
|
|
CA2110514A1
(en)
|
1991-07-05 |
1993-01-21 |
Raymond Baker |
Aromatic compounds, pharmaceutical compositions containing them and their use in therapy
|
|
CA2110725A1
(en)
|
1991-07-10 |
1993-01-21 |
Andrew P. Owens |
Aromatic compounds, compositions containing them and their use in therapy
|
|
US5495047A
(en)
|
1991-07-10 |
1996-02-27 |
Merck, Sharp & Dohme (Ltd.) |
Fused tricyclic compounds, pharmaceutical compositions containing them and their use in therapy
|
|
MY110227A
(en)
|
1991-08-12 |
1998-03-31 |
Ciba Geigy Ag |
1-acylpiperindine compounds.
|
|
CA2112397A1
(en)
|
1991-08-20 |
1993-03-04 |
Raymond Baker |
Azacyclic compounds, processes for their preparation and pharmaceutical compositions containing them
|
|
DK0533280T4
(da)
|
1991-09-20 |
2005-02-28 |
Glaxo Group Ltd |
Ny medicinsk anvendelse af tachykininantagonister
|
|
CZ59394A3
(en)
|
1991-09-26 |
1994-11-16 |
Pfizer |
Condensed tricyclic heterocycles containing nitrogen as antagonists of p substance receptor, process of their preparation, intermediates, pharmaceutical preparations in which they are comprised and use
|
|
US5753674A
(en)
|
1991-10-22 |
1998-05-19 |
Octamer, Inc. |
Adenosine diphosphoribose polymerase binding nitroso aromatic compounds useful as retroviral inactivating agents, anti-retroviral agents, anti-retroviral agents and anti-tumor agents
|
|
WO1993009116A1
(en)
|
1991-11-07 |
1993-05-13 |
Yoshitomi Pharmaceutical Industries, Ltd. |
Quinuclidine compound and medicinal use thereof
|
|
WO1993010073A1
(en)
|
1991-11-12 |
1993-05-27 |
Pfizer Inc. |
Acyclic ethylenediamine derivatives as substance p receptor antagonists
|
|
CA2083891A1
(en)
|
1991-12-03 |
1993-06-04 |
Angus Murray Macleod |
Heterocyclic compounds, compositions containing them and their use in therapy
|
|
HU9203780D0
(en)
|
1991-12-12 |
1993-03-29 |
Sandoz Ag |
Stabilized pharmaceutical products of hmg-coa reductase inhibitor and method for producing them
|
|
GB9200535D0
(en)
|
1992-01-10 |
1992-02-26 |
Fujisawa Pharmaceutical Co |
New compound
|
|
GB9201179D0
(en)
|
1992-01-21 |
1992-03-11 |
Glaxo Group Ltd |
Chemical compounds
|
|
US5328927A
(en)
|
1992-03-03 |
1994-07-12 |
Merck Sharpe & Dohme, Ltd. |
Hetercyclic compounds, processes for their preparation and pharmaceutical compositions containing them
|
|
JP2656702B2
(ja)
|
1992-03-23 |
1997-09-24 |
ファイザー製薬株式会社 |
ペプチド性キヌクリジン
|
|
FR2689888B1
(fr)
|
1992-04-10 |
1994-06-10 |
Rhone Poulenc Rorer Sa |
Nouveaux derives de perhydroisoindole, leur preparation et les compositions pharmaceutiques qui les contiennent.
|
|
WO1993021181A1
(en)
|
1992-04-15 |
1993-10-28 |
Merck Sharp & Dohme Limited |
Azacyclic compounds
|
|
GB2266529A
(en)
|
1992-05-01 |
1993-11-03 |
Merck Sharp & Dohme |
Tetrahydroisoquinoline derivatives
|
|
EP0641328B1
(en)
|
1992-05-18 |
2001-11-21 |
Pfizer Inc. |
Bridged aza-bicyclic derivatives as substance p antagonists
|
|
GB9211193D0
(en)
|
1992-05-27 |
1992-07-08 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
US5719147A
(en)
|
1992-06-29 |
1998-02-17 |
Merck & Co., Inc. |
Morpholine and thiomorpholine tachykinin receptor antagonists
|
|
CA2099233A1
(en)
|
1992-06-29 |
1993-12-30 |
Conrad P. Dorn |
Morpholine and thiomorpholine tachykinin receptor antagonists
|
|
US5637699A
(en)
|
1992-06-29 |
1997-06-10 |
Merck & Co., Inc. |
Process for preparing morpholine tachykinin receptor antagonists
|
|
US5612336A
(en)
|
1992-07-13 |
1997-03-18 |
Merck, Sharp & Dohme Ltd. |
Heterocyclic amide derivatives as tachykinin antagonists
|
|
EP1251170A3
(en)
|
1992-07-17 |
2002-10-30 |
Ribozyme Pharmaceuticals, Inc. |
Method and reagent for treatment of NF-kappaB dependent animal diseases
|
|
GB2268931A
(en)
|
1992-07-22 |
1994-01-26 |
Merck Sharp & Dohme |
Azabicyclic tachykinin-receptor antagonists
|
|
JPH07508993A
(ja)
|
1992-07-28 |
1995-10-05 |
メルク シヤープ エンド ドーム リミテツド |
アザサイクリック化合物
|
|
GB2269170A
(en)
|
1992-07-29 |
1994-02-02 |
Merck Sharp & Dohme |
Azatricyclic tachykinin antagonists
|
|
WO1994003429A1
(en)
|
1992-07-31 |
1994-02-17 |
Merck Sharp & Dohme Limited |
Substituted amines as tachykinin receptor antagonists
|
|
AU4396193A
(en)
|
1992-08-04 |
1994-03-03 |
Pfizer Inc. |
3-benzylamino-2-phenyl-piperidine derivatives as substance p receptor antagonists
|
|
GB9216911D0
(en)
|
1992-08-10 |
1992-09-23 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
ES2153841T3
(es)
|
1992-08-13 |
2001-03-16 |
Warner Lambert Co |
Antagonistas de la taciquinina.
|
|
US5721255A
(en)
|
1992-08-19 |
1998-02-24 |
Pfizer Inc. |
Substituted benzylamino nitrogen containing non-aromatic heterocycles
|
|
US5387595A
(en)
|
1992-08-26 |
1995-02-07 |
Merck & Co., Inc. |
Alicyclic compounds as tachykinin receptor antagonists
|
|
DE69315920T2
(de)
|
1992-09-04 |
1998-06-10 |
Takeda Chemical Industries Ltd |
Kondensierte heterozyklische Verbindungen, deren Herstellung und Verwendung
|
|
WO1994005625A1
(en)
|
1992-09-10 |
1994-03-17 |
Merck Sharp & Dohme Limited |
Alcohols and ethers with aromatic substituents as tachykinin-antagonists
|
|
GB9220286D0
(en)
|
1992-09-25 |
1992-11-11 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
JP2656699B2
(ja)
|
1992-10-21 |
1997-09-24 |
ファイザー製薬株式会社 |
置換ベンジルアミノキヌクリジン
|
|
GB9222262D0
(en)
|
1992-10-23 |
1992-12-09 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
GB9222486D0
(en)
|
1992-10-26 |
1992-12-09 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
JP2656700B2
(ja)
|
1992-10-28 |
1997-09-24 |
ファイザー製薬株式会社 |
置換キヌクリジン誘導体
|
|
EP0666856B1
(en)
|
1992-10-28 |
2000-01-05 |
MERCK SHARP & DOHME LTD. |
4-arylmethyloxymethyl piperidines as tachykinin antagonists
|
|
AU5342894A
(en)
|
1992-10-30 |
1994-05-24 |
Merck Sharp & Dohme Limited |
Tachykinin antagonists
|
|
DK0668863T3
(da)
|
1992-11-12 |
1997-06-30 |
Pfizer |
Quinuclidinderivat som substans P-antagonist
|
|
US5261188A
(en)
|
1992-11-23 |
1993-11-16 |
The Standard Products Company |
Belt weatherstrip with bulb
|
|
DE69328975T2
(de)
|
1992-12-10 |
2000-11-09 |
Pfizer |
Aminomethylen substituierte heterocyclische verbindungen und ihre verwendung alssubstanz p antagonisten
|
|
US5604260A
(en)
|
1992-12-11 |
1997-02-18 |
Merck Frosst Canada Inc. |
5-methanesulfonamido-1-indanones as an inhibitor of cyclooxygenase-2
|
|
US5661162A
(en)
|
1992-12-14 |
1997-08-26 |
Merck Sharp & Dohme Limited |
4-aminomethyl/thiomethyl/sulfonylmethyl-4-phenylpiperdines as tachykinin receptor antagonists
|
|
GB9226581D0
(en)
|
1992-12-21 |
1993-02-17 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
CA2111902A1
(en)
|
1992-12-21 |
1994-06-22 |
Jack Beuford Campbell |
Antitumor compositions and methods of treatment
|
|
GB9300051D0
(en)
|
1993-01-04 |
1993-03-03 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
EP0764644A1
(en)
|
1993-01-15 |
1997-03-26 |
G.D. Searle & Co. |
Use of medicaments containing 3,4-diaryl furans and analogs thereof for treating a gastrointestinal condition
|
|
EP0610793A1
(en)
|
1993-02-08 |
1994-08-17 |
Takeda Chemical Industries, Ltd. |
Tetracyclic morpholine derivatives and their use or analgesics
|
|
AU679207B2
(en)
|
1993-02-18 |
1997-06-26 |
Merck Sharp & Dohme Limited |
Azacyclic compounds, compositions containing them and their use as tachykinin antagonists
|
|
WO1994019320A1
(en)
|
1993-02-22 |
1994-09-01 |
Merck Sharp & Dohme Limited |
Aromatic compounds, compositions containing them and their use in therapy
|
|
WO1994019357A1
(en)
|
1993-02-23 |
1994-09-01 |
Merrell Dow Pharmaceuticals Inc. |
Farnesyl:protein transferase inhibitors as anticancer agents
|
|
US5298627A
(en)
|
1993-03-03 |
1994-03-29 |
Warner-Lambert Company |
Process for trans-6-[2-(substituted-pyrrol-1-yl)alkyl]pyran-2-one inhibitors of cholesterol synthesis
|
|
AU6226494A
(en)
|
1993-03-04 |
1994-09-26 |
Pfizer Inc. |
Spiroazacyclic derivatives as substance p antagonists
|
|
US5409944A
(en)
|
1993-03-12 |
1995-04-25 |
Merck Frosst Canada, Inc. |
Alkanesulfonamido-1-indanone derivatives as inhibitors of cyclooxygenase
|
|
CA2118985A1
(en)
|
1993-04-02 |
1994-10-03 |
Dinesh V. Patel |
Heterocyclic inhibitors of farnesyl protein transferase
|
|
US5496833A
(en)
|
1993-04-13 |
1996-03-05 |
Merck Sharp & Dohme Limited |
Piperidine tachykinin receptor antagonists
|
|
ATE158580T1
(de)
|
1993-05-06 |
1997-10-15 |
Merrell Pharma Inc |
Substituierte pyrrolidin-3-alkyl-piperidine verwendbar als tachykinin-antagonisten
|
|
AU6909194A
(en)
|
1993-05-14 |
1994-12-12 |
Board Of Regents, The University Of Texas System |
Preparation of n-cyanodithioimino-carbonates and 3-mercapto-5-amino-1h-1,2,4-triazole
|
|
US5602098A
(en)
|
1993-05-18 |
1997-02-11 |
University Of Pittsburgh |
Inhibition of farnesyltransferase
|
|
IL109646A0
(en)
|
1993-05-19 |
1994-08-26 |
Pfizer |
Heteroatom substituted alkyl benzylamino-quinuclidines
|
|
US5380738A
(en)
|
1993-05-21 |
1995-01-10 |
Monsanto Company |
2-substituted oxazoles further substituted by 4-fluorophenyl and 4-methylsulfonylphenyl as antiinflammatory agents
|
|
AU680020B2
(en)
|
1993-06-07 |
1997-07-17 |
Merck & Co., Inc. |
Spiro-substituted azacycles as neurokinin antagonists
|
|
US5436265A
(en)
|
1993-11-12 |
1995-07-25 |
Merck Frosst Canada, Inc. |
1-aroyl-3-indolyl alkanoic acids and derivatives thereof useful as anti-inflammatory agents
|
|
US5474995A
(en)
|
1993-06-24 |
1995-12-12 |
Merck Frosst Canada, Inc. |
Phenyl heterocycles as cox-2 inhibitors
|
|
GB9602877D0
(en)
|
1996-02-13 |
1996-04-10 |
Merck Frosst Canada Inc |
3,4-Diaryl-2-hydroxy-2,5- dihydrofurans as prodrugs to cox-2 inhibitors
|
|
EP0634402A1
(en)
|
1993-07-14 |
1995-01-18 |
Takeda Chemical Industries, Ltd. |
Isochinolinone derivatives, their production and use
|
|
ATE171945T1
(de)
|
1993-07-15 |
1998-10-15 |
Pfizer |
Benzyloxychinuclidine als substanz p antagonisten
|
|
TW365603B
(en)
|
1993-07-30 |
1999-08-01 |
Rhone Poulenc Rorer Sa |
Novel perhydroisoindole derivatives, their preparation and pharmaceutical compositions which contain them
|
|
GB9315808D0
(en)
|
1993-07-30 |
1993-09-15 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
GB9317987D0
(en)
|
1993-08-26 |
1993-10-13 |
Glaxo Group Ltd |
Chemical compounds
|
|
US5703065A
(en)
|
1993-09-17 |
1997-12-30 |
Pfizer Inc. |
Heteroarylamino and heteroarylsulfonamido substituted 3-benyzlaminomethyl piperidines and related compounds
|
|
DE69433744T2
(de)
|
1993-09-17 |
2004-10-14 |
Pfizer Inc. |
3-amino-5-carboxy-substituierte piperidine und 3-amino-4-carboxy-substituierte pyrrolidine als tachykinin-antagonisten
|
|
WO1995008542A1
(fr)
|
1993-09-22 |
1995-03-30 |
Kyowa Hakko Kogyo Co., Ltd. |
Inhibiteur de la farnesyl-transferase
|
|
IS4208A
(is)
|
1993-09-22 |
1995-03-23 |
Glaxo Group Limited |
3-(tetrazólýl-benzyl)amínó-piperadidín afleiður
|
|
IL111235A
(en)
|
1993-10-15 |
2001-03-19 |
Schering Plough Corp |
Medicinal preparations for inhibiting protein G activity and for the treatment of malignant diseases, containing tricyclic compounds, some such new compounds and a process for the preparation of some of them
|
|
HUT76057A
(en)
|
1993-10-15 |
1997-06-30 |
Schering Corp |
Tricyclic sulfonamide compounds, pharmaceutical compositions containing them, which are useful for inhibition of g-protein function and for treatment of proliferative diseases and process for producing them
|
|
US5719148A
(en)
|
1993-10-15 |
1998-02-17 |
Schering Corporation |
Tricyclic amide and urea compounds useful for inhibition of g-protein function and for treatment of proliferative diseases
|
|
CA2174105C
(en)
|
1993-10-15 |
2002-02-12 |
W. Robert Bishop |
Tricyclic carbamate compounds useful for inhibition of g-protein function and for treatment of proliferative diseases
|
|
US5721236A
(en)
|
1993-10-15 |
1998-02-24 |
Schering Corporation |
Tricyclic carbamate compounds useful for inhibition of G-protein function and for treatment of proliferative diseases
|
|
US5661152A
(en)
|
1993-10-15 |
1997-08-26 |
Schering Corporation |
Tricyclic sulfonamide compounds useful for inhibition of G-protein function and for treatment of proliferative diseases
|
|
EP0725790B1
(en)
|
1993-10-25 |
2001-04-18 |
PARKE DAVIS & COMPANY |
Substituted tetra- and pentapeptide inhibitors of protein:farnesyl transferase
|
|
AU7947594A
(en)
|
1993-10-27 |
1995-05-22 |
Merck Sharp & Dohme Limited |
Substituted amides as tachykinin antagonists
|
|
US5344991A
(en)
|
1993-10-29 |
1994-09-06 |
G.D. Searle & Co. |
1,2 diarylcyclopentenyl compounds for the treatment of inflammation
|
|
ES2130452T3
(es)
|
1993-11-04 |
1999-07-01 |
Abbott Lab |
Derivados de ciclobutano utilizados como inhibidores de la escualeno-sintetasa y de la farnesiltransferasa proteica.
|
|
US5783593A
(en)
|
1993-11-04 |
1998-07-21 |
Abbott Laboratories |
Inhibitors of squalene synthetase and protein farnesyltransferase
|
|
HUT75308A
(en)
|
1993-11-05 |
1997-05-28 |
Warner Lambert Co |
Substituted di- and tripeptide inhibitors of protein:farnesyl transferase
|
|
US6403577B1
(en)
|
1993-11-17 |
2002-06-11 |
Eli Lilly And Company |
Hexamethyleneiminyl tachykinin receptor antagonists
|
|
US5466823A
(en)
|
1993-11-30 |
1995-11-14 |
G.D. Searle & Co. |
Substituted pyrazolyl benzenesulfonamides
|
|
IT1271462B
(it)
|
1993-12-03 |
1997-05-28 |
Menarini Farma Ind |
Antagonisti delle tachichinine,procedimento per la loro preparazione e loro impiego in formulazioni farmaceutiche.
|
|
US5484799A
(en)
|
1993-12-09 |
1996-01-16 |
Abbott Laboratories |
Antifungal dorrigocin derivatives
|
|
IL111960A
(en)
|
1993-12-17 |
1999-12-22 |
Merck & Co Inc |
Morpholines and thiomorpholines their preparation and pharmaceutical compositions containing them
|
|
CA2176130A1
(en)
|
1993-12-21 |
1995-06-29 |
Thomas Alan Crowell |
Non-peptide tachykinin receptor antagonists
|
|
ATE278687T1
(de)
|
1993-12-29 |
2004-10-15 |
Merck Sharp & Dohme |
Substituierte morpholinderivate und ihre verwendung als therapeutische mittel
|
|
US5854239A
(en)
|
1993-12-29 |
1998-12-29 |
Pfizer Inc. |
Diazabicyclic neuokinin antagonists
|
|
CA2180746A1
(en)
|
1994-01-13 |
1995-07-20 |
Raymond Baker |
Gem-disubstituted azacyclic tachykinin antagonists
|
|
CA2181376A1
(en)
|
1994-01-28 |
1995-08-03 |
Malcolm Maccoss |
Aralkylamino substituted azacyclic therapeutic agents
|
|
US5393790A
(en)
|
1994-02-10 |
1995-02-28 |
G.D. Searle & Co. |
Substituted spiro compounds for the treatment of inflammation
|
|
GB9402688D0
(en)
|
1994-02-11 |
1994-04-06 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
US5610165A
(en)
|
1994-02-17 |
1997-03-11 |
Merck & Co., Inc. |
N-acylpiperidine tachykinin antagonists
|
|
TW385308B
(en)
|
1994-03-04 |
2000-03-21 |
Merck & Co Inc |
Prodrugs of morpholine tachykinin receptor antagonists
|
|
WO1995024612A1
(de)
|
1994-03-07 |
1995-09-14 |
International Business Machines Corporation |
Verfahren und vorrichtung zur schnellen interpolation von zwischenwerten aus periodischen phasenverschobenen signalen und zur erkennung von defekten in einem drehkörper
|
|
GB9404485D0
(en)
|
1994-03-09 |
1994-04-20 |
Cancer Res Campaign Tech |
Benzamide analogues
|
|
CN1151156A
(zh)
|
1994-03-15 |
1997-06-04 |
卫材株式会社 |
异戊二烯基转移酶抑制剂
|
|
FR2718136B1
(fr)
|
1994-03-29 |
1996-06-21 |
Sanofi Sa |
Composés aromatiques aminés, procédé pour leur obtention et compositions pharmaceutiques les contenant.
|
|
IL113196A0
(en)
|
1994-03-31 |
1995-06-29 |
Bristol Myers Squibb Co |
Imidazole derivatives and pharmaceutical compositions containing the same
|
|
US5523430A
(en)
|
1994-04-14 |
1996-06-04 |
Bristol-Myers Squibb Company |
Protein farnesyl transferase inhibitors
|
|
US5610145A
(en)
|
1994-04-15 |
1997-03-11 |
Warner-Lambert Company |
Tachykinin antagonists
|
|
IL113472A0
(en)
|
1994-04-29 |
1995-07-31 |
Lilly Co Eli |
Non-peptidyl tachykinin receptor antogonists
|
|
CA2189141A1
(en)
|
1994-05-05 |
1995-11-16 |
Karen Elizabeth Haworth |
Morpholine derivatives and their use as antagonists of tachikinins
|
|
EE9600186A
(et)
|
1994-05-07 |
1997-08-15 |
Boehringer Ingelheim Kg |
Neurokiniini (tahhüülkiniini) antagonistid
|
|
US5510510A
(en)
|
1994-05-10 |
1996-04-23 |
Bristol-Meyers Squibb Company |
Inhibitors of farnesyl protein transferase
|
|
US5563255A
(en)
|
1994-05-31 |
1996-10-08 |
Isis Pharmaceuticals, Inc. |
Antisense oligonucleotide modulation of raf gene expression
|
|
NZ287284A
(en)
|
1994-06-06 |
1998-10-28 |
Warner Lambert Co |
N-[2-(phenyl(substituted)ethylamino)-1-(indolylmethyl)-1-methyl -2-oxoethyl] carbamic acid ester derivatives, medicaments and intermediates
|
|
DE69507476D1
(de)
|
1994-06-10 |
1999-03-04 |
Rhone Poulenc Rorer Sa |
Farnesyl-transferase-inhibitoren, ihre herstellung und sie enthaltende pharmazeutische zusammensetzungen
|
|
EP0686629A3
(en)
|
1994-06-10 |
1999-02-10 |
Eli Lilly And Company |
Cyclohexyl tachykinine receptor antagonists
|
|
US5571792A
(en)
|
1994-06-30 |
1996-11-05 |
Warner-Lambert Company |
Histidine and homohistidine derivatives as inhibitors of protein farnesyltransferase
|
|
HUT77948A
(hu)
|
1994-07-12 |
1998-12-28 |
Eli Lilly And Co., |
Heterociklusos tachikinin-receptor antagonisták
|
|
CA2154116A1
(en)
|
1994-07-22 |
1996-01-23 |
Philip Arthur Hipskind |
1-aryl-2-acetamidopentanone derivatives for use as tachykinin receptor antagonists
|
|
GB9415996D0
(en)
|
1994-08-08 |
1994-09-28 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
GB9415997D0
(en)
|
1994-08-08 |
1994-09-28 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
WO1996005529A1
(en)
|
1994-08-09 |
1996-02-22 |
Micron Optics, Inc. |
Temperature compensated fiber fabry-perot filters
|
|
TW432061B
(en)
|
1994-08-09 |
2001-05-01 |
Pfizer Res & Dev |
Lactams
|
|
AU3192395A
(en)
|
1994-08-11 |
1996-03-07 |
Banyu Pharmaceutical Co., Ltd. |
Substituted amide derivative
|
|
CA2155448A1
(en)
|
1994-08-11 |
1996-02-12 |
Katerina Leftheris |
Inhibitors of farnesyl protein transferase
|
|
DK0705903T3
(da)
|
1994-08-12 |
2001-08-27 |
Myriad Genetics Inc |
Mutationer i det 17q-koblede bryst- og ovariecancerprædisponeringen
|
|
AU691331B2
(en)
|
1994-08-12 |
1998-05-14 |
Myriad Genetics, Inc. |
Method for diagnosing a predisposition for breast and ovarian cancer
|
|
EP0805154A1
(en)
|
1994-08-12 |
1997-11-05 |
Banyu Pharmaceutical Co., Ltd. |
N,n-disubstituted amic acid derivative
|
|
US5824678A
(en)
|
1994-08-15 |
1998-10-20 |
Merck Sharp & Dohme Ltd. |
Morpholine derivatives and their use as therapeutic agents
|
|
DE4429506B4
(de)
|
1994-08-19 |
2007-09-13 |
Degussa Gmbh |
Verfahren zur Extraktion natürlicher Carotinoid-Farbstoffe
|
|
DE4429653C2
(de)
|
1994-08-20 |
1997-04-03 |
Anton Dr More |
Konverter und Verfahren zum Frischen von Metallschmelzen insbesondere von Roheisen zu Stahl
|
|
HU221434B
(en)
|
1994-08-25 |
2002-10-28 |
Merrell Pharma Inc |
Substituted piperidines, pharmaceutical compositions containing them and their use
|
|
EP0699655B1
(en)
|
1994-08-29 |
1997-09-24 |
Akzo Nobel N.V. |
Process for the preparation of quaternary diesters
|
|
GB9417956D0
(en)
|
1994-09-02 |
1994-10-26 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
GB9418545D0
(en)
|
1994-09-15 |
1994-11-02 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
US5457107A
(en)
|
1994-09-16 |
1995-10-10 |
Merck & Co., Inc. |
Polymorphic form of a tachykinin receptor antagonist
|
|
WO1996010562A1
(en)
|
1994-09-30 |
1996-04-11 |
Novartis Ag |
1-acyl-4-aliphatylaminopiperidine compounds
|
|
TW397825B
(en)
|
1994-10-14 |
2000-07-11 |
Novartis Ag |
Aroyl-piperidine derivatives
|
|
FR2725986B1
(fr)
|
1994-10-21 |
1996-11-29 |
Adir |
Nouveaux derives de piperidine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
|
|
DE69534213T2
(de)
|
1994-10-25 |
2006-01-12 |
Astrazeneca Ab |
Therapeutisch wirksame Heterocyclen
|
|
GB9421709D0
(en)
|
1994-10-27 |
1994-12-14 |
Zeneca Ltd |
Therapeutic compounds
|
|
WO1996016443A1
(en)
|
1994-11-22 |
1996-05-30 |
Philips Electronics N.V. |
Semiconductor device with a carrier body on which a substrate with a semiconductor element is fastened by means of a glue layer and on which a pattern of conductor tracks is fastened
|
|
EP0714891A1
(en)
|
1994-11-22 |
1996-06-05 |
Eli Lilly And Company |
Heterocyclic tachykinin receptor antagonists
|
|
FR2727411B1
(fr)
|
1994-11-30 |
1997-01-03 |
Rhone Poulenc Rorer Sa |
Nouveaux derives de perhydroisoindole, leur preparation et les compositions pharmaceutiques qui les contiennent
|
|
JPH10510261A
(ja)
|
1994-12-09 |
1998-10-06 |
ワーナー−ランバート・カンパニー |
タンパク質：ファルネシルトランスフェラーゼの置換テトラーおよびペンタペプチド阻害剤
|
|
IL116323A0
(en)
|
1994-12-13 |
1996-03-31 |
Sandoz Ag |
Tachykinin antagonists their preparation and pharmaceutical compositions containing them
|
|
US5589483A
(en)
|
1994-12-21 |
1996-12-31 |
Geron Corporation |
Isoquinoline poly (ADP-ribose) polymerase inhibitors to treat skin diseases associated with cellular senescence
|
|
GB9426103D0
(en)
|
1994-12-23 |
1995-02-22 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
EP0802953A2
(en)
|
1995-01-09 |
1997-10-29 |
Magla International Ltd |
Wear resistant image printing on latex surfaces
|
|
JP3925662B2
(ja)
|
1995-01-12 |
2007-06-06 |
グラクソ，グループ，リミテッド |
タキキニンアンタゴニスト活性を有するピペリジン誘導体
|
|
CA2207252C
(en)
|
1995-01-12 |
2014-02-25 |
University Of Pittsburgh |
Inhibitors of prenyl transferases
|
|
FR2729390A1
(fr)
|
1995-01-18 |
1996-07-19 |
Rhone Poulenc Rorer Sa |
Nouveaux inhibiteurs de farnesyl transferase, leur preparation et les compositions pharmaceutiques qui les contiennent
|
|
FR2729951B1
(fr)
|
1995-01-30 |
1997-04-18 |
Sanofi Sa |
Nouveaux composes heterocycliques, procede pour leur preparation et compositions pharmaceutiques en contenant
|
|
FR2730491B1
(fr)
|
1995-02-09 |
1997-03-14 |
Rhone Poulenc Rorer Sa |
Nouveaux inhibiteurs de farnesyl transferase, leur preparation et les compositions pharmaceutiques qui les contiennent
|
|
FR2730492B1
(fr)
|
1995-02-09 |
1997-03-14 |
Rhone Poulenc Rorer Sa |
Nouveaux inhibiteurs de farnesyl transferase, leur preparation et les compositions pharmaceutiques qui les contiennent
|
|
US5633272A
(en)
|
1995-02-13 |
1997-05-27 |
Talley; John J. |
Substituted isoxazoles for the treatment of inflammation
|
|
GB9505492D0
(en)
|
1995-03-18 |
1995-05-03 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
GB9505491D0
(en)
|
1995-03-18 |
1995-05-03 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
US5554641A
(en)
|
1995-03-20 |
1996-09-10 |
Horwell; David C. |
Nonpeptides as tachykinin antagonists
|
|
GB9505692D0
(en)
|
1995-03-21 |
1995-05-10 |
Glaxo Group Ltd |
Chemical compounds
|
|
TW394773B
(en)
|
1995-03-24 |
2000-06-21 |
Takeda Chemical Industries Ltd |
Cyclic compounds for antagonizing tachykinin receptor, substance p receptor and neurokinin a receptor, their production and pharmaceutical composition
|
|
US5684013A
(en)
|
1995-03-24 |
1997-11-04 |
Schering Corporation |
Tricyclic compounds useful for inhibition of g-protein function and for treatment of proliferative diseases
|
|
US5700806A
(en)
|
1995-03-24 |
1997-12-23 |
Schering Corporation |
Tricyclic amide and urea compounds useful for inhibition of G-protein function and for treatment of proliferative diseases
|
|
IL117580A0
(en)
|
1995-03-29 |
1996-07-23 |
Merck & Co Inc |
Inhibitors of farnesyl-protein transferase and pharmaceutical compositions containing them
|
|
US5565568A
(en)
|
1995-04-06 |
1996-10-15 |
Eli Lilly And Company |
2-acylaminopropanamides as tachykinin receptor antagonists
|
|
US5891872A
(en)
|
1995-04-07 |
1999-04-06 |
Schering Corporation |
Tricyclic compounds
|
|
IL117798A
(en)
|
1995-04-07 |
2001-11-25 |
Schering Plough Corp |
Tricyclic compounds useful for inhibiting the function of protein - G and for the treatment of malignant diseases, and pharmaceutical preparations containing them
|
|
US5712280A
(en)
|
1995-04-07 |
1998-01-27 |
Schering Corporation |
Tricyclic compounds useful for inhibition of G-protein function and for treatment of proliferative diseases
|
|
AU5432696A
(en)
|
1995-04-07 |
1996-10-23 |
Pharmacopeia, Inc. |
Carbonyl-piperazinyl and piperidinil compounds which inhibit farnesyl protein transferase
|
|
CA2217006C
(en)
|
1995-04-13 |
2001-05-22 |
Hoechst Marion Roussel, Inc. |
Novel substituted piperazine derivatives having tachykinin receptor antagonists activity
|
|
US5831115A
(en)
|
1995-04-21 |
1998-11-03 |
Abbott Laboratories |
Inhibitors of squalene synthase and protein farnesyltransferase
|
|
IL118101A0
(en)
|
1995-05-03 |
1996-09-12 |
Abbott Lab |
Inhibitors of farnesyltransferase
|
|
JP3071829B2
(ja)
|
1995-05-25 |
2000-07-31 |
藤沢薬品工業株式会社 |
ニューロキニン受容体拮抗剤としての１−ベンゾイル−２−（インドリル−３−アルキル）−ピペラジン誘導体
|
|
US5919780A
(en)
|
1995-06-16 |
1999-07-06 |
Warner Lambert Company |
Tricyclic inhibitors of protein farnesyltransferase
|
|
GB9513118D0
(en)
|
1995-06-28 |
1995-08-30 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
GB9513117D0
(en)
|
1995-06-28 |
1995-08-30 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
GB9513121D0
(en)
|
1995-06-28 |
1995-08-30 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
CA2226292C
(en)
|
1995-07-07 |
2001-12-11 |
Pfizer Inc. |
Substituted benzolactam compounds as substance p antagonists
|
|
FR2736641B1
(fr)
|
1995-07-10 |
1997-08-22 |
Rhone Poulenc Rorer Sa |
Nouveaux inhibiteurs de farnesyl transferase, leur preparation et les compositions pharmaceutiques qui les contiennent
|
|
AT402617B
(de)
|
1995-07-11 |
1997-07-25 |
Datacon Schweitzer & Zeindl Gm |
Anlage zum automatisierten, hermetischen anlage zum automatisierten, hermetischen verschliessen von gehäusen verschliessen von gehäusen
|
|
FR2736638B1
(fr)
|
1995-07-12 |
1997-08-22 |
Rhone Poulenc Rorer Sa |
Nouveaux inhibiteurs de farnesyl transferase, leur preparation et les compositions pharmaceutiques qui les contiennent
|
|
CH690163A5
(fr)
|
1995-07-28 |
2000-05-31 |
Symphar Sa |
Dérivés gem-diphosphonates substitués utiles en tant qu'agents anti-cancers.
|
|
ES2183004T3
(es)
*
|
1995-08-02 |
2003-03-16 |
Univ Newcastle Ventures Ltd |
Compuestos de benzimidazol.
|
|
TW340842B
(en)
|
1995-08-24 |
1998-09-21 |
Pfizer |
Substituted benzylaminopiperidine compounds
|
|
US6020343A
(en)
|
1995-10-13 |
2000-02-01 |
Merck Frosst Canada, Inc. |
(Methylsulfonyl)phenyl-2-(5H)-furanones as COX-2 inhibitors
|
|
WO1997014671A1
(en)
|
1995-10-18 |
1997-04-24 |
Merck & Co., Inc. |
Cyclopentyl tachykinin receptor antagonists
|
|
JP4533466B2
(ja)
|
1995-11-06 |
2010-09-01 |
ユニバーシティ オブ ピッツバーグ |
蛋白質イソプレニルトランスフェラーゼの阻害剤
|
|
DE19541283A1
(de)
|
1995-11-06 |
1997-05-07 |
Boehringer Ingelheim Kg |
Neue Aminosäurederivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Zusammensetzungen
|
|
GB9523244D0
(en)
|
1995-11-14 |
1996-01-17 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
DE59609305D1
(de)
|
1995-11-17 |
2002-07-11 |
Biotechnolog Forschung Gmbh |
Epothilon-Derivate und deren Herstellung
|
|
AU704139B2
(en)
|
1995-11-22 |
1999-04-15 |
Merck & Co., Inc. |
Inhibitors of farnesyl-protein transferase
|
|
EP1019410A1
(en)
|
1995-11-23 |
2000-07-19 |
MERCK SHARP & DOHME LTD. |
Spiro-piperidine derivatives and their use as tachykinin antagonists
|
|
GB9524157D0
(en)
|
1995-11-25 |
1996-01-24 |
Pfizer Ltd |
Therapeutic agents
|
|
HU224225B1
(hu)
|
1995-12-01 |
2005-06-28 |
Sankyo Co. Ltd. |
Tachikinin receptor antagonista hatású heterociklusos vegyületek, ezek előállítási eljárása és alkalmazásuk gyógyszerkészítmények előállítására
|
|
DE69620445T2
(de)
|
1995-12-08 |
2002-12-12 |
Janssen Pharmaceutica Nv |
(imidazol-5-yl)methyl-2-chinolinoderivate als farnesyl protein transferase inhibitoren
|
|
GB9525296D0
(en)
|
1995-12-11 |
1996-02-07 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
WO1997023478A1
(en)
|
1995-12-22 |
1997-07-03 |
Schering Corporation |
Tricyclic amides useful for inhibition of g-protein function and for treatment of proliferative diseases
|
|
AU1529997A
(en)
|
1996-01-16 |
1997-08-11 |
Warner-Lambert Company |
Substituted histidine inhibitors of protein farnesyltransferase
|
|
US6673927B2
(en)
|
1996-02-16 |
2004-01-06 |
Societe De Conseils De Recherches Et D'applications Scientifiques, S.A.S. |
Farnesyl transferase inhibitors
|
|
WO1997038665A2
(en)
|
1996-04-03 |
1997-10-23 |
Merck & Co., Inc. |
Inhibitors of farnesyl-protein transferase
|
|
PL195955B1
(pl)
|
1996-04-12 |
2007-11-30 |
Searle & Co |
Związek, pochodna benzenosulfonamidu, sposób jegowytwarzania, kompozycja farmaceutyczna zawierająca go oraz jego zastosowanie
|
|
NZ332712A
(en)
|
1996-05-22 |
2000-07-28 |
Warner Lambert Co |
Polypeptide inhibitors of protein farnesyl transferase
|
|
CA2260216A1
(en)
|
1996-07-15 |
1998-01-22 |
Bristol-Myers Squibb Company |
Thiadioxobenzodiazepine inhibitors of farnesyl protein transferase
|
|
US5861419A
(en)
|
1996-07-18 |
1999-01-19 |
Merck Frosst Canad, Inc. |
Substituted pyridines as selective cyclooxygenase-2 inhibitors
|
|
JP2001527517A
(ja)
|
1996-07-26 |
2001-12-25 |
スーザン・ピー・ペリーネ |
血液、ウイルス性および細胞性疾患の治療組成物
|
|
JP4579351B2
(ja)
|
1996-12-03 |
2010-11-10 |
スローン−ケッタリング インスティトュート フォア キャンサー リサーチ |
エポチロンの合成とその中間体及びその類似物並びにその使用
|
|
JP2002511054A
(ja)
|
1996-12-30 |
2002-04-09 |
メルク エンド カンパニー インコーポレーテッド |
ファルネシル蛋白トランスフェラーゼ阻害薬
|
|
JP2001507699A
(ja)
|
1996-12-30 |
2001-06-12 |
メルク エンド カンパニー インコーポレーテッド |
ファルネシル蛋白トランスフェラーゼ阻害薬
|
|
WO1999059973A1
(en)
|
1998-05-15 |
1999-11-25 |
Guilford Pharmaceuticals Inc. |
Carboxamide compounds, compositions, and methods for inhibiting parp activity
|
|
AU1158000A
(en)
|
1998-10-30 |
2000-05-22 |
Lonza A.G. |
Method for producing 4- ((2',5'- diamino-6'- halopyrimidine- 4'-YL)amino)- cyclopent- 2-enylmethanols
|
|
DE59911249D1
(de)
|
1998-11-03 |
2005-01-13 |
Abbott Gmbh & Co Kg |
Substituierte 2-phenylbenzimidazole, deren herstellung und anwendung
|
|
SK6742001A3
(en)
*
|
1998-11-17 |
2001-12-03 |
Basf Ag |
2-phenylbenzimidazoles and 2-phenylindoles, and production and use thereof
|
|
PT1133477E
(pt)
|
1998-11-27 |
2004-06-30 |
Abbott Gmbh & Co Kg |
Benzimidazois substituidos e a utilizacao dos mesmos como inibidores da parp
|
|
JP2002536968A
(ja)
|
1999-01-29 |
2002-11-05 |
イムクローン システムズ インコーポレイティド |
Ｋｄｒに特異的な抗体およびその使用
|
|
GB9904387D0
(en)
|
1999-02-25 |
1999-04-21 |
Pharmacia & Upjohn Spa |
Antitumour synergistic composition
|
|
WO2000061186A1
(en)
|
1999-04-08 |
2000-10-19 |
Arch Development Corporation |
Use of anti-vegf antibody to enhance radiation in cancer therapy
|
|
DE19918211A1
(de)
|
1999-04-22 |
2000-10-26 |
Basf Ag |
Cycloalkylsubstituierte Benzimidazole, deren Herstellung und Anwendung
|
|
DE19920936A1
(de)
*
|
1999-05-07 |
2000-11-09 |
Basf Ag |
Heterozyklisch substituierte Benzimidazole, deren Herstellung und Anwendung
|
|
WO2001021615A1
(en)
|
1999-09-17 |
2001-03-29 |
Yamanouchi Pharmaceutical Co., Ltd. |
Benzimidazole derivatives
|
|
US6545004B1
(en)
|
1999-10-27 |
2003-04-08 |
Cytokinetics, Inc. |
Methods and compositions utilizing quinazolinones
|
|
KR20020062930A
(ko)
|
1999-10-27 |
2002-07-31 |
싸이토키네틱스, 인코포레이티드 |
퀴나졸리논을 사용하는 방법 및 조성물
|
|
ES2290115T3
(es)
*
|
2000-02-01 |
2008-02-16 |
ABBOTT GMBH & CO. KG |
Compuestos heterociclicos y su aplicacion como inhibidores de parp.
|
|
DE10022925A1
(de)
*
|
2000-05-11 |
2001-11-15 |
Basf Ag |
Substituierte Indole als PARP-Inhibitoren
|
|
WO2002056880A1
(en)
|
2001-01-19 |
2002-07-25 |
Cytokinetics, Inc. |
Triphenylmethane kinesin inhibitors
|
|
US6992082B2
(en)
|
2001-01-19 |
2006-01-31 |
Cytokinetics, Inc. |
Phenothiazine kinesin inhibitors
|
|
JPWO2002068407A1
(ja)
|
2001-02-28 |
2004-06-24 |
山之内製薬株式会社 |
ベンゾイミダゾール化合物
|
|
WO2002083139A1
(en)
|
2001-04-10 |
2002-10-24 |
Merck & Co., Inc. |
Inhibitors of akt activity
|
|
AU2002251266A1
(en)
|
2001-04-10 |
2002-10-28 |
Merck Sharp And Dohme Limited |
Inhibitors of akt activity
|
|
JP4361276B2
(ja)
|
2001-04-10 |
2009-11-11 |
メルク エンド カムパニー インコーポレーテッド |
Ａｋｔ活性の阻害物質
|
|
WO2002083140A1
(en)
|
2001-04-10 |
2002-10-24 |
Merck & Co., Inc. |
Inhibitors of akt activity
|
|
WO2003007959A1
(en)
|
2001-07-16 |
2003-01-30 |
Fujisawa Pharmaceutical Co., Ltd. |
Quinoxaline derivatives which have parp inhibitory action
|
|
WO2003013526A1
(en)
|
2001-08-08 |
2003-02-20 |
Merck & Co. Inc. |
Anticoagulant compounds
|
|
CA2465491A1
(en)
|
2001-11-07 |
2003-05-15 |
Merck & Co., Inc. |
Mitotic kinesin inhibitors
|
|
CA2467726A1
(en)
|
2001-12-06 |
2003-06-19 |
Merck & Co., Inc. |
Mitotic kinesin inhibitors
|
|
ATE372341T1
(de)
|
2001-12-06 |
2007-09-15 |
Merck & Co Inc |
Inhibitoren von mitotischem kinesin
|
|
JP4391825B2
(ja)
|
2001-12-06 |
2009-12-24 |
メルク エンド カムパニー インコーポレーテッド |
有糸分裂キネシン阻害剤
|
|
CA2468156A1
(en)
|
2001-12-06 |
2003-06-19 |
Merck & Co., Inc. |
Azolopyrimidinone compounds and their use
|
|
US7262186B2
(en)
|
2001-12-06 |
2007-08-28 |
Merck & Co., Inc. |
Substituted pyrazolo[3,4-d] pyrimidinones as a mitotic kinesin inhibitor
|
|
JP4606739B2
(ja)
|
2002-01-18 |
2011-01-05 |
ピエール、ファーブル、メディカマン |
新規抗ｉｇｆ−ｉｒ抗体およびその使用
|
|
JPWO2003062234A1
(ja)
|
2002-01-23 |
2005-05-19 |
山之内製薬株式会社 |
キノキサリン化合物
|
|
DE60329990D1
(de)
|
2002-03-08 |
2009-12-24 |
Merck & Co Inc |
Mitotische kinesin-hemmer
|
|
WO2003086279A2
(en)
|
2002-04-08 |
2003-10-23 |
Merck & Co., Inc. |
Inhibitors of akt activity
|
|
JP4394961B2
(ja)
|
2002-04-08 |
2010-01-06 |
メルク エンド カムパニー インコーポレーテッド |
Ａｋｔ活性の阻害剤としての融合キノキサリン誘導体
|
|
EP1496906A4
(en)
|
2002-04-08 |
2006-05-03 |
Merck & Co Inc |
INHIBITORS OF AKT ACTIVITY
|
|
US7223738B2
(en)
|
2002-04-08 |
2007-05-29 |
Merck & Co., Inc. |
Inhibitors of Akt activity
|
|
JP2006506401A
(ja)
|
2002-05-23 |
2006-02-23 |
メルク エンド カムパニー インコーポレーテッド |
有糸分裂キネシン阻害薬
|
|
CA2483627A1
(en)
|
2002-05-23 |
2003-12-04 |
Merck & Co., Inc. |
Mitotic kinesin inhibitors
|
|
US20040034078A1
(en)
|
2002-06-14 |
2004-02-19 |
Agouron Pharmaceuticals, Inc. |
Benzimidazole inhibitors of poly(ADP-ribosyl) polymerase
|
|
ES2282647T3
(es)
|
2002-06-14 |
2007-10-16 |
MERCK & CO., INC. |
Inhibidores de cinesina mitotica.
|
|
JP4377323B2
(ja)
|
2002-06-14 |
2009-12-02 |
メルク エンド カムパニー インコーポレーテッド |
有糸分裂キネシン阻害剤
|
|
WO2004014861A1
(ja)
|
2002-08-09 |
2004-02-19 |
Kyorin Pharmaceutical Co., Ltd. |
4-置換キノリン-8-カルボン酸アミド誘導体とその薬理上許容される付加塩
|
|
WO2004037171A2
(en)
|
2002-10-18 |
2004-05-06 |
Merck & Co., Inc. |
Mitotic kinesin inhibitors
|
|
WO2004058700A2
(en)
|
2002-12-20 |
2004-07-15 |
Merck & Co., Inc. |
Mitotic kinesin inhibitors
|
|
EP1581497A4
(en)
|
2002-12-20 |
2009-03-18 |
Merck & Co Inc |
INHIBITORS OF MITOTIC KINESINE
|
|
AU2003296405A1
(en)
*
|
2003-01-06 |
2004-08-10 |
Eli Lilly And Company |
Fused heterocyclic derivatives as ppar modulators
|
|
WO2004087050A2
(en)
|
2003-03-28 |
2004-10-14 |
Merck & Co., Inc. |
Mitotic kinesin inhibitors
|
|
HU0301154D0
(en)
|
2003-04-28 |
2003-07-28 |
Hideg Kalman Dr |
Pharmaceutical composition
|
|
EP1706386A1
(en)
*
|
2003-12-22 |
2006-10-04 |
Eli Lilly And Company |
Bicyclic derivatives as ppar modulators
|
|
EP1722797A4
(en)
|
2004-02-26 |
2008-03-19 |
Inotek Pharmaceuticals Corp |
ISOCHINOLINE DERIVATIVES AND METHOD FOR THE APPLICATION THEREOF
|
|
AU2005259188B2
(en)
|
2004-06-30 |
2011-03-31 |
Janssen Pharmaceutica N.V. |
Quinazolinone derivatives as PARP inhibitors
|
|
WO2006021801A1
(en)
|
2004-08-26 |
2006-03-02 |
Kudos Pharmaceuticals Limited |
4-heteroarylmethyl substituted phthalazinone derivatives
|
|
ES2337275T3
(es)
*
|
2004-09-22 |
2010-04-22 |
Pfizer, Inc. |
Procedimiento de preparacion de inhidores de poli(adp-ribosa)-polimrerasas.
|
|
TWI375673B
(en)
*
|
2005-04-11 |
2012-11-01 |
Abbott Lab |
1h-benzimidazole-4-carboxamides substituted with a quaternary carbon at the 2-position are potent parp inhibitors
|
|
US7728026B2
(en)
*
|
2005-04-11 |
2010-06-01 |
Abbott Laboratories, Inc. |
2-substituted-1 h-benzimidazile-4-carboxamides are PARP inhibitors
|
|
ES2378692T3
(es)
*
|
2005-09-29 |
2012-04-17 |
Abbott Laboratories |
Las 1H-benzimidazol-4-carboxamidas sustituidas con fenilo en la posición 2 son potentes inhibidores de PARP
|
|
ATE461923T1
(de)
*
|
2005-11-15 |
2010-04-15 |
Abbott Lab |
Substituierte 1h-benzimidazol-4-carbonsäureamide sind wirksame parp-inhibitoren
|
|
JP4611441B2
(ja)
*
|
2006-04-03 |
2011-01-12 |
イステイチユート・デイ・リチエルケ・デイ・ビオロジア・モレコラーレ・ピ・アンジエレツテイ・エツセ・ピー・アー |
ポリ（ａｄｐ−リボース）ポリメラーゼ（ｐａｒｐ）阻害剤としてのアミド置換インダゾール及びベンゾトリアゾール誘導体
|
|
ES2385849T3
(es)
*
|
2006-05-02 |
2012-08-01 |
Abbott Laboratories |
Las 1H-bencimidazol-4-carboxamidas substituidas son potentes inhibidores de la PARP
|
|
US20090062268A1
(en)
*
|
2007-08-27 |
2009-03-05 |
Lead Therapeutics, Inc. |
Novel inhibitors of poly(adp-ribose)polymerase (parp)
|
|
WO2009099736A2
(en)
*
|
2008-02-06 |
2009-08-13 |
Lead Therapeutics, Inc. |
Benzoxazole carboxamide inhibitors of poly(adp-ribose)polymerase (parp)
|