ATE372341T1 - Inhibitoren von mitotischem kinesin - Google Patents

Inhibitoren von mitotischem kinesin

Info

Publication number
ATE372341T1
ATE372341T1 AT02804714T AT02804714T ATE372341T1 AT E372341 T1 ATE372341 T1 AT E372341T1 AT 02804714 T AT02804714 T AT 02804714T AT 02804714 T AT02804714 T AT 02804714T AT E372341 T1 ATE372341 T1 AT E372341T1
Authority
AT
Austria
Prior art keywords
inhibitors
mitotic kinesin
compounds
ksp kinesin
treating
Prior art date
Application number
AT02804714T
Other languages
English (en)
Inventor
Mark Fraley
George Hartman
William Hoffman
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Application granted granted Critical
Publication of ATE372341T1 publication Critical patent/ATE372341T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT02804714T 2001-12-06 2002-12-02 Inhibitoren von mitotischem kinesin ATE372341T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US33838301P 2001-12-06 2001-12-06

Publications (1)

Publication Number Publication Date
ATE372341T1 true ATE372341T1 (de) 2007-09-15

Family

ID=23324603

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02804714T ATE372341T1 (de) 2001-12-06 2002-12-02 Inhibitoren von mitotischem kinesin

Country Status (9)

Country Link
US (1) US7378411B2 (de)
EP (1) EP1463733B1 (de)
JP (1) JP4597519B2 (de)
AT (1) ATE372341T1 (de)
AU (1) AU2002357053B2 (de)
CA (1) CA2467722A1 (de)
DE (1) DE60222302T2 (de)
ES (1) ES2291543T3 (de)
WO (1) WO2003050064A2 (de)

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Also Published As

Publication number Publication date
DE60222302D1 (de) 2007-10-18
DE60222302T2 (de) 2008-05-29
US7378411B2 (en) 2008-05-27
WO2003050064B1 (en) 2003-12-18
AU2002357053A1 (en) 2003-06-23
EP1463733B1 (de) 2007-09-05
EP1463733A2 (de) 2004-10-06
US20050228003A1 (en) 2005-10-13
CA2467722A1 (en) 2003-06-19
ES2291543T3 (es) 2008-03-01
JP2005516007A (ja) 2005-06-02
WO2003050064A3 (en) 2003-10-16
WO2003050064A2 (en) 2003-06-19
JP4597519B2 (ja) 2010-12-15
EP1463733A4 (de) 2006-01-11
AU2002357053B2 (en) 2008-05-15

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