HK1063433A1 - Inhibitors against the production and release of inflammatory cytokines - Google Patents
Inhibitors against the production and release of inflammatory cytokinesInfo
- Publication number
- HK1063433A1 HK1063433A1 HK04106223A HK04106223A HK1063433A1 HK 1063433 A1 HK1063433 A1 HK 1063433A1 HK 04106223 A HK04106223 A HK 04106223A HK 04106223 A HK04106223 A HK 04106223A HK 1063433 A1 HK1063433 A1 HK 1063433A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- release
- production
- inflammatory cytokines
- inhibitors against
- group
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/325—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
- C07D207/327—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
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US8263657B2 (en) * | 2000-12-18 | 2012-09-11 | Institute Of Medicinal Molecular Design, Inc. | Inhibitors against the production and release of inflammatory cytokines |
ES2610611T3 (es) | 2002-01-18 | 2017-04-28 | Astellas Pharma Inc. | Derivado de 2-acilaminotiazol o sal del mismo |
EP2311818B1 (en) * | 2002-02-28 | 2013-01-16 | Novartis AG | Combination of a 5-phenylthiazole compound as PI3 kinase inhibitor with an antiinflammatory, bronchodilatory or antihistamine drug |
PE20030968A1 (es) | 2002-02-28 | 2004-01-12 | Novartis Ag | Derivados de 5-feniltiazol como inhibidores de cinasas |
CA2487900A1 (en) * | 2002-06-05 | 2003-12-18 | Institute Of Medicinal Molecular Design, Inc. | Immunity-related protein kinase inhibitors |
JPWO2003103647A1 (ja) * | 2002-06-05 | 2005-10-06 | 株式会社医薬分子設計研究所 | Ap−1及びnfat活性化阻害剤 |
EA008769B1 (ru) * | 2002-06-05 | 2007-08-31 | Инститьют Оф Медисинал Молекьюлар Дизайн. Инк. | Лекарственное средство для лечения диабета |
EP1514544A4 (en) * | 2002-06-06 | 2009-01-07 | Inst Med Molecular Design Inc | HYPO-ALLERGENIC |
CN1658855B (zh) * | 2002-06-06 | 2010-04-28 | 株式会社医药分子设计研究所 | O-取代羟基芳基衍生物 |
WO2003103654A1 (ja) * | 2002-06-10 | 2003-12-18 | 株式会社医薬分子設計研究所 | NF−κB活性化阻害剤 |
EP1535610A4 (en) * | 2002-06-10 | 2008-12-31 | Inst Med Molecular Design Inc | THERAPEUTIC CANCER |
AU2003242124A1 (en) * | 2002-06-11 | 2003-12-22 | Institute Of Medicinal Molecular Design, Inc. | Medicament for treatment of neurodegenerative diseases |
AU2003244000A1 (en) * | 2002-06-26 | 2004-01-19 | Signal Creation Inc. | DRUG COMPOSITION CONTAINING NF-KappaB INHIBITOR |
AU2003251944B2 (en) * | 2002-07-15 | 2008-06-26 | Myriad Genetics, Inc. | Compounds, compositions, and methods employing same |
CN100506813C (zh) | 2002-10-01 | 2009-07-01 | 宝生物工程株式会社 | 新的查耳酮类化合物及其应用 |
WO2004044463A1 (ja) * | 2002-11-12 | 2004-05-27 | Nok Corporation | ゴム状弾性部品 |
EP1600445A4 (en) * | 2003-02-14 | 2008-06-11 | Signal Creation Inc | CURATIVE PREPARATION |
EP1620429B1 (en) * | 2003-04-11 | 2009-04-01 | Glenmark Pharmaceuticals S.A. | Novel heterocyclic compounds useful for the treatment of inflammatory and allergic disorders: process for their preparation and pharmaceutical compositions containing them |
US20070042997A1 (en) * | 2003-07-16 | 2007-02-22 | Akiko Itai | Medicament for treatment of dermal pigmentation |
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WO2004006906A2 (en) | 2002-07-15 | 2004-01-22 | Combinatorx, Incorporated | Methods for the treatment of neoplasms |
US20070042997A1 (en) * | 2003-07-16 | 2007-02-22 | Akiko Itai | Medicament for treatment of dermal pigmentation |
JP4217981B2 (ja) | 2005-02-08 | 2009-02-04 | Smc株式会社 | 直動・回転複合アクチュエータ |
JP4217916B2 (ja) | 2006-02-15 | 2009-02-04 | 三菱ふそうトラック・バス株式会社 | ハイブリッド電気自動車の制御装置 |
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2001
- 2001-12-18 US US10/433,619 patent/US8263657B2/en not_active Expired - Fee Related
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- 2001-12-18 WO PCT/JP2001/011084 patent/WO2002049632A1/ja active Application Filing
- 2001-12-18 KR KR1020037008036A patent/KR101088557B1/ko not_active IP Right Cessation
- 2001-12-18 EP EP07015076A patent/EP1844766B1/en not_active Expired - Lifetime
- 2001-12-18 KR KR1020097016971A patent/KR20090090406A/ko not_active Application Discontinuation
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- 2001-12-18 AT AT01271124T patent/ATE548031T1/de active
- 2001-12-18 CN CNA2007101400603A patent/CN101125138A/zh active Pending
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- 2001-12-18 UA UA2003076746A patent/UA82827C2/uk unknown
- 2001-12-18 EP EP07015427A patent/EP1847263A3/en not_active Withdrawn
- 2001-12-18 CN CN2010101039763A patent/CN101849953B/zh not_active Expired - Fee Related
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2004
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2007
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2010
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