FR2372821A1 - Preparation de gamma-pyrones - Google Patents

Preparation de gamma-pyrones

Info

Publication number
FR2372821A1
FR2372821A1 FR7719250A FR7719250A FR2372821A1 FR 2372821 A1 FR2372821 A1 FR 2372821A1 FR 7719250 A FR7719250 A FR 7719250A FR 7719250 A FR7719250 A FR 7719250A FR 2372821 A1 FR2372821 A1 FR 2372821A1
Authority
FR
France
Prior art keywords
pyrones
gamma
preparation
ethylmaltol
maltol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7719250A
Other languages
English (en)
Other versions
FR2372821B1 (fr
Inventor
Thomas Mott Brennan
Daniel Patrick Brannegan
Paul Douglas Weeks
Donald Ernest Kuhla
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/721,885 external-priority patent/US4082717A/en
Application filed by Pfizer Inc filed Critical Pfizer Inc
Publication of FR2372821A1 publication Critical patent/FR2372821A1/fr
Application granted granted Critical
Publication of FR2372821B1 publication Critical patent/FR2372821B1/fr
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/32Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/34Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D309/36Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
    • C07D309/40Oxygen atoms attached in positions 3 and 4, e.g. maltol

Abstract

L'invention concerne un procédé de préparation de gamma-pyrones. On prépare des gamma-pyrones, en particulier le maltol(2méthyl-3-hydroxy-4H-pyran-4-one) et l'éthylmaltol (2-éthyl-3hydroxy-4H-pyran-4-one) en hydrolysant certains pyrannes intermédiaires préparés en faisant réagir des alcools furfuryliques, en particulier le 1-(2-furyl)-2-éthanol, en solution aqueuse avec un oxydant halogéné, par exemple, le chlore, le brome, le chlorure de brome, l'acide hypochloreux, l'acide hypobromeux et leurs mélanges. Certains intermédiaires du type 4-halo-dihydropyranne sont nouveaux ainsi que leur préparation. Le maltol et l'éthylmaltol ainsi obtenus sont utilisés en particulier pour rehausser la saveur et l'arôme de divers produits alimentaires, et comme ingrédients dans des parfums.
FR7719250A 1976-08-02 1977-06-23 Preparation de gamma-pyrones Granted FR2372821A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US71090176A 1976-08-02 1976-08-02
US05/721,885 US4082717A (en) 1976-08-02 1976-09-09 Preparation of gamma-pyrones

Publications (2)

Publication Number Publication Date
FR2372821A1 true FR2372821A1 (fr) 1978-06-30
FR2372821B1 FR2372821B1 (fr) 1980-10-17

Family

ID=27108548

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7719250A Granted FR2372821A1 (fr) 1976-08-02 1977-06-23 Preparation de gamma-pyrones

Country Status (36)

Country Link
JP (7) JPS5318578A (fr)
AR (1) AR216080A1 (fr)
AT (3) AT362790B (fr)
BE (1) BE855965A (fr)
BG (4) BG29136A3 (fr)
BR (1) BR7703970A (fr)
CA (3) CA1095921A (fr)
CH (4) CH625798A5 (fr)
CS (3) CS203921B2 (fr)
DD (1) DD132494A5 (fr)
DE (3) DE2760221C2 (fr)
DK (4) DK153483C (fr)
EG (1) EG13080A (fr)
ES (5) ES459994A1 (fr)
FI (6) FI72722C (fr)
FR (1) FR2372821A1 (fr)
GB (5) GB1538372A (fr)
GR (1) GR68938B (fr)
HK (5) HK30381A (fr)
HU (4) HU185686B (fr)
IE (5) IE45644B1 (fr)
IT (1) IT1106258B (fr)
LU (1) LU77600A1 (fr)
MX (1) MX4597E (fr)
MY (3) MY8100267A (fr)
NL (5) NL170955C (fr)
NO (7) NO150561C (fr)
NZ (1) NZ184342A (fr)
PH (5) PH13557A (fr)
PL (4) PL115496B1 (fr)
PT (1) PT66694B (fr)
RO (4) RO78952A (fr)
SE (6) SE433079B (fr)
SU (2) SU955859A3 (fr)
TR (1) TR19652A (fr)
YU (4) YU40166B (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2402654A1 (fr) * 1977-09-12 1979-04-06 Shinetsu Chemical Co Nouveaux derives de x tetrahydropyrannone(5)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1095921A (fr) * 1976-08-02 1981-02-17 Thomas M. Brennan Preparation de gamma-pyrones
JPS5444675A (en) * 1977-09-12 1979-04-09 Shin Etsu Chem Co Ltd Production of 3-hydroxy-4-pyrone analog
JPS5741226U (fr) * 1980-08-20 1982-03-05
JPS59135008U (ja) * 1983-02-28 1984-09-10 松下電工株式会社 分電盤装置
JPS6050245A (ja) * 1983-08-29 1985-03-19 Nissan Motor Co Ltd 内燃機関の燃料噴射装置
JPH0226945Y2 (fr) * 1985-09-11 1990-07-20
JP2586607B2 (ja) * 1987-10-30 1997-03-05 日産化学工業株式会社 光学活性アルコールの製造法
UY30986A1 (es) 2007-03-28 2008-09-02 Apotex Technologies Inc Derivados fluorinados de deferiprona
PT2268282E (pt) 2008-04-25 2015-02-05 Apotex Technologies Inc Formulação líquida de deferiprona com sabor agradável
BR112012000079A2 (pt) 2009-07-03 2017-07-25 Apotex Tech Inc derivados fluorados de 3-hidroxipiridin-4-onas
WO2017168309A1 (fr) * 2016-03-29 2017-10-05 Dr. Reddy’S Laboratories Limited Procédé de préparation d'éribuline et de ses intermédiaires
CN108609456B (zh) * 2016-12-13 2021-03-12 奥的斯电梯公司 可打开扩展面板及具有其的电梯吊顶,轿厢和系统
CN111606879A (zh) * 2020-05-25 2020-09-01 安徽金禾实业股份有限公司 一锅法制备2-羟甲基-3-烷氧基-4h-吡喃-4-酮的方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3621063A (en) * 1968-12-24 1971-11-16 Monsanto Co Unsaturated acyclic ketones
NL7607730A (nl) * 1975-08-28 1977-03-02 Pfizer Werkwijze voor de bereiding van gamma-pyronen.

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3491122A (en) * 1966-09-14 1970-01-20 Monsanto Co Synthesis of 4-pyrones
US3547912A (en) * 1968-07-29 1970-12-15 American Home Prod Derivatives of 2h-pyran-3(6h)-ones and preparation thereof
JPS5145565B1 (fr) * 1968-10-12 1976-12-04
US3832357A (en) * 1971-05-26 1974-08-27 Daicel Ltd Process for preparation of 3-hydroxy-2-alkyl-4-pyrone
JPS5212166A (en) * 1975-07-17 1977-01-29 Tatsuya Shono Process for preparation of 4-pyron derivatives
CA1095921A (fr) 1976-08-02 1981-02-17 Thomas M. Brennan Preparation de gamma-pyrones

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3621063A (en) * 1968-12-24 1971-11-16 Monsanto Co Unsaturated acyclic ketones
NL7607730A (nl) * 1975-08-28 1977-03-02 Pfizer Werkwijze voor de bereiding van gamma-pyronen.

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2402654A1 (fr) * 1977-09-12 1979-04-06 Shinetsu Chemical Co Nouveaux derives de x tetrahydropyrannone(5)

Also Published As

Publication number Publication date
NZ184342A (en) 1978-09-25
ATA124380A (de) 1981-03-15
NO150042C (no) 1984-08-15
BG28989A4 (en) 1980-08-15
PL199798A1 (pl) 1979-08-27
NO150043B (no) 1984-04-30
BE855965A (fr) 1977-12-21
ES459994A1 (es) 1978-11-16
NL182805B (nl) 1987-12-16
GB1538372A (en) 1979-01-17
IE790586L (en) 1978-02-02
IE790585L (en) 1978-02-02
JPS5436267A (en) 1979-03-16
FI73424B (fi) 1987-06-30
FI831700A0 (fi) 1983-05-16
DD132494A5 (de) 1978-10-04
DK154079B (da) 1988-10-10
CH626357A5 (en) 1981-11-13
FI831703A0 (fi) 1983-05-16
JPS5618596B2 (fr) 1981-04-30
NO150559C (no) 1984-11-07
JPS5618597B2 (fr) 1981-04-30
SE8200521L (sv) 1982-01-29
FI72119C (fi) 1987-04-13
FI72720B (fi) 1987-03-31
PL115586B1 (en) 1981-04-30
FI72721B (fi) 1987-03-31
NL182477B (nl) 1987-10-16
DK325986A (da) 1986-07-09
FI72722C (fi) 1987-07-10
AU2601777A (en) 1978-09-21
DK154079C (da) 1989-02-27
NO821849L (no) 1978-02-03
NO821851L (no) 1978-02-03
FI771934A (fr) 1978-02-03
NL182805C (nl) 1988-05-16
JPS5420500B2 (fr) 1979-07-23
NO150559B (no) 1984-07-30
GB1538371A (en) 1979-01-17
GB1538373A (en) 1979-01-17
PH14625A (en) 1981-10-12
FR2372821B1 (fr) 1980-10-17
NL182477C (nl) 1988-03-16
IE790584L (en) 1978-02-02
FI831704L (fi) 1983-05-16
FI831700L (fi) 1983-05-16
RO74367A (fr) 1981-11-24
SE8200519L (sv) 1982-01-29
JPS5318578A (en) 1978-02-20
NO150560C (no) 1984-11-07
FI72722B (fi) 1987-03-31
FI72723B (fi) 1987-03-31
ES470743A1 (es) 1979-01-16
DE2760221C2 (fr) 1989-10-05
NL8105537A (nl) 1982-04-01
DK153401B (da) 1988-07-11
ES470745A1 (es) 1979-01-16
JPS5436270A (en) 1979-03-16
SE433079B (sv) 1984-05-07
NL8105539A (nl) 1982-04-01
SE444565B (sv) 1986-04-21
NO834236L (no) 1978-02-03
FI72720C (fi) 1987-07-10
EG13080A (en) 1981-03-31
CS203922B2 (en) 1981-03-31
IE790587L (en) 1978-02-02
LU77600A1 (fr) 1978-02-01
FI831702A0 (fi) 1983-05-16
AT363470B (de) 1981-08-10
FI72723C (fi) 1987-07-10
NL7706811A (nl) 1978-02-06
FI73424C (fi) 1987-10-09
TR19652A (tr) 1979-09-17
HK30581A (en) 1981-07-10
GR68938B (fr) 1982-03-29
DK153401C (da) 1988-11-28
FI831704A0 (fi) 1983-05-16
YU270382A (en) 1983-10-31
NL182476B (nl) 1987-10-16
RO78951A2 (fr) 1982-04-12
MY8100267A (en) 1981-12-31
SE8200520L (sv) 1982-01-29
MY8100262A (en) 1981-12-31
DE2760220C2 (fr) 1987-08-20
AT362790B (de) 1981-06-10
HK30781A (en) 1981-07-10
FI831701L (fi) 1983-05-16
ES470746A1 (es) 1979-01-16
PT66694B (en) 1978-11-17
DK326086A (da) 1986-07-09
JPS5436268A (en) 1979-03-16
CS203921B2 (en) 1981-03-31
DK326186D0 (da) 1986-07-09
CS203923B2 (en) 1981-03-31
AT364356B (de) 1981-10-12
CH625235A5 (en) 1981-09-15
NO821847L (no) 1978-02-03
DE2728499A1 (de) 1978-02-09
NO151365B (no) 1984-12-17
ATA440477A (de) 1980-11-15
NO150043C (no) 1984-08-15
NL182478B (nl) 1987-10-16
NL8105540A (nl) 1982-04-01
JPS5436266A (en) 1979-03-16
YU42613B (en) 1988-10-31
PH13557A (en) 1980-06-26
CH625798A5 (en) 1981-10-15
IE45642B1 (en) 1982-10-20
MX4597E (es) 1982-06-25
NL182478C (nl) 1988-03-16
IE45643B1 (en) 1982-10-20
DK153483C (da) 1988-11-28
FI831702L (fi) 1983-05-16
DK326186A (da) 1986-07-09
PL215006A1 (pl) 1979-12-17
SE445041B (sv) 1986-05-26
NO150042B (no) 1984-04-30
CA1110254A (fr) 1981-10-06
NO151365C (no) 1985-03-27
DK153484B (da) 1988-07-18
RO78953A (fr) 1982-04-12
SE445042B (sv) 1986-05-26
NO821848L (no) 1978-02-03
YU166383A (en) 1986-02-28
SE8200522L (sv) 1982-01-29
NO150561B (no) 1984-07-30
MY8100287A (en) 1981-12-31
YU43190B (en) 1989-04-30
PL215007A1 (pl) 1979-12-17
SU955859A3 (ru) 1982-08-30
GB1538375A (en) 1979-01-17
IE45645B1 (en) 1982-10-20
SE7707035L (sv) 1978-02-03
DK326086D0 (da) 1986-07-09
BG28988A4 (en) 1980-08-15
JPS5436269A (en) 1979-03-16
ES470744A1 (es) 1979-01-16
HU185687B (en) 1985-03-28
DK325986D0 (da) 1986-07-09
DE2728499C2 (de) 1986-04-03
HK30481A (en) 1981-07-10
PT66694A (en) 1977-07-01
NO821850L (no) 1978-02-03
IE45644B1 (en) 1982-10-20
YU146977A (en) 1983-06-30
PL215008A1 (pl) 1979-12-17
NL170955B (nl) 1982-08-16
NO772193L (no) 1978-02-03
AR216080A1 (es) 1979-11-30
JPS5814433B2 (ja) 1983-03-18
NO150560B (no) 1984-07-30
FI72119B (fi) 1986-12-31
FI72721C (fi) 1987-07-10
HU186026B (en) 1985-05-28
SE8200518L (sv) 1982-01-29
NL8105538A (nl) 1982-04-01
CA1117541A (fr) 1982-02-02
PL115496B1 (en) 1981-04-30
PL115497B1 (en) 1981-04-30
JPS5729034B2 (fr) 1982-06-19
YU40166B (en) 1985-08-31
SE444564B (sv) 1986-04-21
NO150561C (no) 1984-11-07
YU274782A (en) 1983-12-31
PH15185A (en) 1982-09-10
NL170955C (nl) 1983-01-17
HK30681A (en) 1981-07-10
SE452616B (sv) 1987-12-07
JPS5436271A (en) 1979-03-16
CA1095921A (fr) 1981-02-17
IE45641B1 (en) 1982-10-20
DK153483B (da) 1988-07-18
ATA124480A (de) 1981-01-15
CH626358A5 (en) 1981-11-13
PH13874A (en) 1980-10-24
DK153484C (da) 1988-11-28
HU180040B (en) 1983-01-28
BR7703970A (pt) 1978-07-04
NL182476C (nl) 1988-03-16
DK276177A (da) 1978-02-03
BG28849A3 (en) 1980-07-15
SU1015826A3 (ru) 1983-04-30
GB1538374A (en) 1979-01-17
HU185686B (en) 1985-03-28
IT1106258B (it) 1985-11-11
HK30381A (en) 1981-07-10
PH13926A (en) 1980-11-04
FI831703L (fi) 1983-05-16
RO78952A (fr) 1982-04-12
BG29136A3 (en) 1980-09-15
IE45641L (en) 1978-02-02
FI831701A0 (fi) 1983-05-16

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