ES2225112T3 - Procedimiento de purificacion de acido lactico a escala industrial. - Google Patents
Procedimiento de purificacion de acido lactico a escala industrial.Info
- Publication number
- ES2225112T3 ES2225112T3 ES00914368T ES00914368T ES2225112T3 ES 2225112 T3 ES2225112 T3 ES 2225112T3 ES 00914368 T ES00914368 T ES 00914368T ES 00914368 T ES00914368 T ES 00914368T ES 2225112 T3 ES2225112 T3 ES 2225112T3
- Authority
- ES
- Spain
- Prior art keywords
- lactic acid
- acid solution
- industrial scale
- concentrated
- processing purification
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/42—Separation; Purification; Stabilisation; Use of additives
- C07C51/43—Separation; Purification; Stabilisation; Use of additives by change of the physical state, e.g. crystallisation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/42—Separation; Purification; Stabilisation; Use of additives
- C07C51/43—Separation; Purification; Stabilisation; Use of additives by change of the physical state, e.g. crystallisation
- C07C51/44—Separation; Purification; Stabilisation; Use of additives by change of the physical state, e.g. crystallisation by distillation
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Crystallography & Structural Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Método de purificación de ácido láctico a escala industrial, que comprende las etapas siguientes: (a) destilación a presión reducida de una solución concentrada de ácido láctico con un contenido total de ácido de por lo menos el 95% en peso y un contenido de ácido láctico monomérico de por lo menos el 80% en peso, basado en la solución concentrada de ácido láctico, siendo la proporción de enantiómeros de ácido láctico en la solución concentrada de ácido láctico diferente de 1, con el fin de formar un concentrado de ácido láctico, y (b) cristalización del concentrado de ácido láctico para formar un ácido láctico puro, en el que la cristalización se lleva a cabo mediante: (i) enfriamiento directo del concentrado de ácido láctico en uno o más cristalizadores de fundido (ii) dilución del concentrado de ácido láctico con agua y cristalización en uno o más cristalizadores por enfriamiento y/o cristalizadores por evaporación, y/o (iii) cristalización en uno o más cristalizadores adiabáticos.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NL1011624 | 1999-03-22 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2225112T3 true ES2225112T3 (es) | 2005-03-16 |
Family
ID=19768882
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES00914368T Expired - Lifetime ES2225112T3 (es) | 1999-03-22 | 2000-03-21 | Procedimiento de purificacion de acido lactico a escala industrial. |
Country Status (11)
Country | Link |
---|---|
US (1) | US6630603B1 (es) |
EP (1) | EP1163200B9 (es) |
JP (3) | JP2002540090A (es) |
CN (1) | CN1285559C (es) |
AT (1) | ATE276994T1 (es) |
AU (1) | AU3575700A (es) |
BR (1) | BRPI0009229B8 (es) |
DE (1) | DE60014047T2 (es) |
DK (1) | DK1163200T3 (es) |
ES (1) | ES2225112T3 (es) |
WO (1) | WO2000056693A1 (es) |
Families Citing this family (44)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU1661901A (en) * | 1999-11-24 | 2001-06-04 | Cargill Dow Llc | Improved lactic acid processing; methods; arrangements; and, products |
NL1013682C2 (nl) * | 1999-11-26 | 2001-05-30 | Purac Biochem Bv | Werkwijze en inrichting voor het zuiveren van een waterige oplossing van melkzuur. |
BR0113940B1 (pt) | 2000-09-15 | 2012-05-02 | processo para preparar derivados de 4 - tioalquilbromobenzeno. | |
WO2002022545A1 (en) * | 2000-09-15 | 2002-03-21 | Purac Biochem B.V. | METHOD FOR THE PURIFICATION OF α-HYDROXI ON INDUSTRIAL SCALE _______________________________________________________ |
US6632966B2 (en) | 2001-08-24 | 2003-10-14 | Purac Biochem B.V. | Method for the preparation of lactic acid and calcium sulphate dihydrate |
EA200400682A1 (ru) | 2001-11-16 | 2004-10-28 | Рэнбакси Лабораториз Лимитед | Способ получения кристаллического имипенема |
EP1471048B1 (en) | 2002-01-29 | 2007-06-13 | Asahi Kasei Chemicals Corporation | Method for producing high purity glycolic acid crystals |
US20050209328A1 (en) * | 2004-03-19 | 2005-09-22 | Allgood Charles C | Alphahydroxyacids with ultra-low metal concentration |
JP5112658B2 (ja) * | 2006-08-11 | 2013-01-09 | 三菱レイヨン株式会社 | α−ヒドロキシカルボン酸の製造方法 |
US8048624B1 (en) | 2007-12-04 | 2011-11-01 | Opx Biotechnologies, Inc. | Compositions and methods for 3-hydroxypropionate bio-production from biomass |
HUE029846T2 (en) * | 2008-10-06 | 2017-04-28 | Sulzer Chemtech Ag | Method and apparatus for separating carboxylic acids and / or carboxylic acid esters |
BE1018561A3 (fr) * | 2008-12-24 | 2011-03-01 | Galactic Sa | Procede de purification de l'acide lactique par cristallisation. |
ES2765889T3 (es) | 2008-12-26 | 2020-06-11 | Toray Industries | Procedimiento para la producción de ácido láctico y procedimiento para la producción de ácido poliláctico |
JP5359348B2 (ja) * | 2009-02-18 | 2013-12-04 | 東レ株式会社 | 高純度乳酸の製造方法 |
PL2275399T3 (pl) | 2009-07-16 | 2014-01-31 | Purac Biochem Bv | Ciekła kompozycja kwasu mlekowego i sposób jej otrzymywania |
DE102009029651A1 (de) | 2009-09-22 | 2011-03-24 | Evonik Röhm Gmbh | Verfahren zur Herstellung freier Carbonsäuren |
US8809027B1 (en) | 2009-09-27 | 2014-08-19 | Opx Biotechnologies, Inc. | Genetically modified organisms for increased microbial production of 3-hydroxypropionic acid involving an oxaloacetate alpha-decarboxylase |
AU2010298004B2 (en) | 2009-09-27 | 2016-02-25 | Opx Biotechnologies, Inc. | Method for producing 3-hydroxypropionic acid and other products |
JP2013536801A (ja) * | 2010-08-28 | 2013-09-26 | ノボマー, インコーポレイテッド | エチレンオキシドからのコハク酸無水物 |
FI20115496A (fi) * | 2011-05-23 | 2012-11-24 | Upm Kymmene Corp | Menetelmä ja laitteisto hydroksikarboksyylihappotuotteen valmistamiseksi ja valkaisusuodatteen käyttö |
FI20115497A (fi) * | 2011-05-23 | 2012-11-24 | Upm Kymmene Corp | Menetelmä ja laitteisto hydroksikarboksyylihappotuotteen erottamiseksi |
CN109182238A (zh) | 2012-08-10 | 2019-01-11 | 嘉吉有限公司 | 用于生产脂肪酸和脂肪酸衍生产物的微生物及方法 |
CN103714636B (zh) * | 2013-03-15 | 2015-12-02 | 福建联迪商用设备有限公司 | 一种批量采集和上传传输密钥tk数据的方法及操作终端 |
US20150119601A1 (en) | 2013-03-15 | 2015-04-30 | Opx Biotechnologies, Inc. | Monofunctional mcr + 3-hp dehydrogenase |
US9512057B2 (en) | 2013-03-15 | 2016-12-06 | Cargill, Incorporated | 3-hydroxypropionic acid compositions |
US11408013B2 (en) | 2013-07-19 | 2022-08-09 | Cargill, Incorporated | Microorganisms and methods for the production of fatty acids and fatty acid derived products |
BR112016001026A2 (pt) | 2013-07-19 | 2017-10-24 | Cargill Inc | organismo geneticamente modificado |
WO2015034036A1 (ja) * | 2013-09-06 | 2015-03-12 | 東レ株式会社 | 乳酸およびポリ乳酸の製造方法 |
US10501399B2 (en) | 2014-03-31 | 2019-12-10 | Toray Industries, Inc. | Lactic acid manufacturing method |
MX2017000367A (es) * | 2014-07-10 | 2017-08-25 | Archer Daniels Midland Co | Proceso novedoso de recuperacion de acido lactico. |
DE102014213637A1 (de) | 2014-07-14 | 2016-01-14 | Thyssenkrupp Ag | Verfahren und Vorrichtung zur Aufkonzentration und Kristallisation von fermentierbaren Carbonsäuren |
ES2930659T3 (es) | 2014-07-28 | 2022-12-20 | Purac Biochem Bv | Procedimiento para la preparación de ácido láctico |
JP2014210825A (ja) * | 2014-08-22 | 2014-11-13 | 富士フイルム株式会社 | プロセシンググルコシダーゼ阻害剤 |
EP2993228B1 (en) | 2014-09-02 | 2019-10-09 | Cargill, Incorporated | Production of fatty acid esters |
EP3196186B1 (en) * | 2014-09-17 | 2019-02-20 | Nippon Shokubai Co., Ltd. | Method for producing vapor composition containing lactic acid |
JP2020506702A (ja) | 2017-02-02 | 2020-03-05 | カーギル インコーポレイテッド | C6−c10脂肪酸誘導体を生成する遺伝子組み換え細胞 |
CN111164215A (zh) * | 2017-10-02 | 2020-05-15 | 代谢探索者公司 | 用于从发酵液产生有机酸盐的方法 |
CN109096097A (zh) * | 2018-08-30 | 2018-12-28 | 河北乐开节能科技股份有限公司 | 一种制取高纯度聚合级结晶乳酸的方法 |
KR20230006541A (ko) | 2020-05-04 | 2023-01-10 | 오츠카 세이야쿠 가부시키가이샤 | 무수 락트산을 합성하는 방법 |
KR20230042586A (ko) * | 2020-07-31 | 2023-03-28 | 미쯔비시 가스 케미칼 컴파니, 인코포레이티드 | α-하이드록시카복실산 조성물의 제조 방법 |
NL2028900B1 (en) | 2021-08-02 | 2023-02-17 | Arapaha B V | A method of closed loop recycling of polylactic acid |
EP4392483A1 (en) * | 2021-08-26 | 2024-07-03 | Futerro S.A. | Valorisation of lactic acid stream in the production process of polylactic acid |
EP4392472A1 (en) * | 2021-08-26 | 2024-07-03 | Futerro S.A. | Valorisation of d-lactic acid stream by l/d separation in the production process of l-polylactic acid |
CN114276232A (zh) * | 2021-10-28 | 2022-04-05 | 欧尚元(天津)有限公司 | 一种超纯级乳酸的制备方法及其制备装置 |
Family Cites Families (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US1594843A (en) * | 1921-08-19 | 1926-08-03 | Du Pont | Purification of lactic acid |
DE593657C (de) * | 1931-07-16 | 1934-03-01 | Byk Guldenwerke Chem Fab Akt G | Verfahren zur Herstellung von fester Milchsaeure |
US2013104A (en) | 1933-01-30 | 1935-09-03 | Du Pont | Purification of lactic acid |
JPS5665841A (en) | 1979-11-02 | 1981-06-03 | Daicel Chem Ind Ltd | Purification of lactic acid |
JPS59139391A (ja) * | 1983-01-28 | 1984-08-10 | Daicel Chem Ind Ltd | アセチルリン酸塩の製法 |
EP0361082A3 (de) * | 1988-09-01 | 1991-09-18 | Henkel KGaA | Fermentative Herstellung von 1,3-Propandiol |
JPH04501652A (ja) * | 1989-06-27 | 1992-03-26 | ユニリーバー・ナームローゼ・ベンノートシャープ | 食用組成物 |
AU6500590A (en) * | 1989-10-17 | 1991-05-16 | Owafin Ag | Process for manufacturing bisphenols |
GB9003201D0 (en) * | 1990-02-13 | 1990-04-11 | Unilever Plc | Cosmetic composition |
AT398982B (de) * | 1993-02-18 | 1995-02-27 | Vogelbusch Gmbh | Verfahren zur abtrennung und reinigung von milchsäure |
JP2809069B2 (ja) * | 1993-10-26 | 1998-10-08 | 株式会社島津製作所 | ラクチドの精製法および重合法 |
JP2830896B2 (ja) | 1993-11-17 | 1998-12-02 | 株式会社島津製作所 | ラクチドの製造法 |
JPH07165753A (ja) | 1993-12-08 | 1995-06-27 | Musashino Kagaku Kenkyusho:Kk | ラクチドの精製方法 |
JPH0811961A (ja) | 1994-06-29 | 1996-01-16 | Yoshino Kogyosho Co Ltd | 泡噴出容器 |
JP2560259B2 (ja) * | 1994-10-21 | 1996-12-04 | 工業技術院長 | ラクチドの製造方法 |
JP3880175B2 (ja) * | 1996-12-20 | 2007-02-14 | 三井化学株式会社 | 乳酸の精製方法 |
JPH10204156A (ja) * | 1997-01-17 | 1998-08-04 | Kyowa Yuka Kk | ポリヒドロキシカルボン酸の製造方法 |
JPH10279577A (ja) * | 1997-04-04 | 1998-10-20 | Shimadzu Corp | 食品添加物用ラクチド及びラクチドの精製方法 |
BE1011197A3 (fr) * | 1997-06-06 | 1999-06-01 | Brussels Biotech En Abrege Bb | Procede de purification d'acide lactique. |
JP2004509092A (ja) * | 2000-09-15 | 2004-03-25 | プラク・ビオヘム・ベー・ブイ | α−ヒドロキシ酸の工業的規模での精製方法 |
JP5359348B2 (ja) * | 2009-02-18 | 2013-12-04 | 東レ株式会社 | 高純度乳酸の製造方法 |
PL2275399T3 (pl) * | 2009-07-16 | 2014-01-31 | Purac Biochem Bv | Ciekła kompozycja kwasu mlekowego i sposób jej otrzymywania |
-
2000
- 2000-03-21 DE DE60014047T patent/DE60014047T2/de not_active Expired - Lifetime
- 2000-03-21 BR BRPI0009229A patent/BRPI0009229B8/pt not_active IP Right Cessation
- 2000-03-21 JP JP2000606557A patent/JP2002540090A/ja active Pending
- 2000-03-21 ES ES00914368T patent/ES2225112T3/es not_active Expired - Lifetime
- 2000-03-21 DK DK00914368T patent/DK1163200T3/da active
- 2000-03-21 AT AT00914368T patent/ATE276994T1/de not_active IP Right Cessation
- 2000-03-21 US US09/937,219 patent/US6630603B1/en not_active Expired - Lifetime
- 2000-03-21 CN CNB008053235A patent/CN1285559C/zh not_active Expired - Lifetime
- 2000-03-21 AU AU35757/00A patent/AU3575700A/en not_active Abandoned
- 2000-03-21 EP EP00914368A patent/EP1163200B9/en not_active Expired - Lifetime
- 2000-03-21 WO PCT/NL2000/000189 patent/WO2000056693A1/en active IP Right Grant
-
2010
- 2010-12-28 JP JP2010292892A patent/JP2011074084A/ja not_active Withdrawn
-
2014
- 2014-05-20 JP JP2014103901A patent/JP6045531B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
DE60014047D1 (de) | 2004-10-28 |
EP1163200B1 (en) | 2004-09-22 |
EP1163200A1 (en) | 2001-12-19 |
ATE276994T1 (de) | 2004-10-15 |
BR0009229B1 (pt) | 2012-12-11 |
DE60014047T2 (de) | 2006-02-23 |
CN1344241A (zh) | 2002-04-10 |
CN1285559C (zh) | 2006-11-22 |
JP2014193895A (ja) | 2014-10-09 |
DK1163200T3 (da) | 2004-11-01 |
WO2000056693A1 (en) | 2000-09-28 |
JP6045531B2 (ja) | 2016-12-14 |
EP1163200B9 (en) | 2005-03-16 |
JP2011074084A (ja) | 2011-04-14 |
US6630603B1 (en) | 2003-10-07 |
AU3575700A (en) | 2000-10-09 |
BRPI0009229B8 (pt) | 2021-05-25 |
JP2002540090A (ja) | 2002-11-26 |
BR0009229A (pt) | 2001-12-26 |
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