DK2332940T3 - Azaindoler, der kan anvendes som inhibitorer af JAK og andre proteinkinaser - Google Patents

Azaindoler, der kan anvendes som inhibitorer af JAK og andre proteinkinaser

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Publication number
DK2332940T3
DK2332940T3 DK10182365.6T DK10182365T DK2332940T3 DK 2332940 T3 DK2332940 T3 DK 2332940T3 DK 10182365 T DK10182365 T DK 10182365T DK 2332940 T3 DK2332940 T3 DK 2332940T3
Authority
DK
Denmark
Prior art keywords
azaindoles
jak
inhibitors
protein kinases
kinases
Prior art date
Application number
DK10182365.6T
Other languages
Danish (da)
English (en)
Inventor
Jian Wang
Francesco Salituro
Luc Farmer
Randy Bethiel
Edmund Harrington
Jeremy Green
John Court
Jon Come
David Lauffer
Alex Aronov
Hayley Binch
Dean Boyall
Jean-Damien Charrier
Simon Everitt
Damien Fraysse
Michael Mortimore
Francoise Pierard
Daniel Robinson
Joanne Pinder
Tiansheng Wang
Albert Pierce
Original Assignee
Vertex Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34971569&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK2332940(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Vertex Pharma filed Critical Vertex Pharma
Application granted granted Critical
Publication of DK2332940T3 publication Critical patent/DK2332940T3/da

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    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
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    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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