CA2560454C - Azaindoles useful as inhibitors of jak and other protein kinases - Google Patents

Azaindoles useful as inhibitors of jak and other protein kinases Download PDF

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Publication number
CA2560454C
CA2560454C CA2560454A CA2560454A CA2560454C CA 2560454 C CA2560454 C CA 2560454C CA 2560454 A CA2560454 A CA 2560454A CA 2560454 A CA2560454 A CA 2560454A CA 2560454 C CA2560454 C CA 2560454C
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Canada
Prior art keywords
optionally substituted
nitrogen
sulfur
oxygen
pharmaceutically acceptable
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Expired - Lifetime
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CA2560454A
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English (en)
French (fr)
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CA2560454A1 (en
Inventor
Francesco Salituro
Luc Farmer
Randy Bethiel
Edmund Harrington
Jeremy Green
John Court
Jon Come
David Lauffer
Alex Aronov
Hayley Binch
Dean Boyall
Jean-Damien Charrier
Simon Everitt
Damien Fraysse
Michael Mortimore
Francoise Pierard
Daniel Robinson
Jian Wang
Tiansheng Wang
Joanne Pinder
Albert Pierce
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Vertex Pharmaceuticals Inc
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Vertex Pharmaceuticals Inc
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Application filed by Vertex Pharmaceuticals Inc filed Critical Vertex Pharmaceuticals Inc
Publication of CA2560454A1 publication Critical patent/CA2560454A1/en
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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
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