TR200402753T4 - 7,8-Dihidro-1,6,9-trioksa-3-aza-siklopenta[a]naftalen'in antidepresan azaheterosiklmetil türevleri. - Google Patents

7,8-Dihidro-1,6,9-trioksa-3-aza-siklopenta[a]naftalen'in antidepresan azaheterosiklmetil türevleri.

Info

Publication number
TR200402753T4
TR200402753T4 TR2004/02753T TR200402753T TR200402753T4 TR 200402753 T4 TR200402753 T4 TR 200402753T4 TR 2004/02753 T TR2004/02753 T TR 2004/02753T TR 200402753 T TR200402753 T TR 200402753T TR 200402753 T4 TR200402753 T4 TR 200402753T4
Authority
TR
Turkey
Prior art keywords
azaheterocyclmethyl
trioxa
cyclopenta
aza
dihydro
Prior art date
Application number
TR2004/02753T
Other languages
English (en)
Inventor
Tran Megan
Paul Stack Gary
Original Assignee
Wyeth
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth filed Critical Wyeth
Publication of TR200402753T4 publication Critical patent/TR200402753T4/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Diabetes (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Gynecology & Obstetrics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

Bu bulus, 7,8-dihidro-1,6,9-trioksa-3-aza-siklopenta[a]naftalen azaheterosiklmetil türevleri antidepresana, bunlari hazirlama islemlerine, kullanma yöntemlerine ve bunlari içeren farmasötik bilesimlere iliskin bir bulustur.
TR2004/02753T 2001-04-30 2002-04-25 7,8-Dihidro-1,6,9-trioksa-3-aza-siklopenta[a]naftalen'in antidepresan azaheterosiklmetil türevleri. TR200402753T4 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US28744901P 2001-04-30 2001-04-30

Publications (1)

Publication Number Publication Date
TR200402753T4 true TR200402753T4 (tr) 2004-11-22

Family

ID=23102960

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2004/02753T TR200402753T4 (tr) 2001-04-30 2002-04-25 7,8-Dihidro-1,6,9-trioksa-3-aza-siklopenta[a]naftalen'in antidepresan azaheterosiklmetil türevleri.

Country Status (14)

Country Link
US (2) US6525075B2 (tr)
EP (1) EP1392700B1 (tr)
JP (1) JP2004528352A (tr)
CN (1) CN1256337C (tr)
AT (1) ATE277934T1 (tr)
BR (1) BR0209407A (tr)
CA (1) CA2445859A1 (tr)
DE (1) DE60201447T2 (tr)
DK (1) DK1392700T3 (tr)
ES (1) ES2225798T3 (tr)
MX (1) MXPA03009829A (tr)
PT (1) PT1392700E (tr)
TR (1) TR200402753T4 (tr)
WO (1) WO2002088140A1 (tr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6815448B2 (en) * 2001-05-07 2004-11-09 Wyeth Azaheterocyclylmethyl derivatives of 7,8-dihydro-1,6,9-trioxa-3-aza-cyclopenta[a]naphthalene as 5-HT1A antagonists
US6800637B2 (en) * 2002-09-12 2004-10-05 Wyeth Antidepressant indolealkyl derivatives of heterocycle-fused benzodioxan methylamines
PT2332940E (pt) 2004-03-30 2013-01-30 Vertex Pharma Azaindoles úteis como inibidores de jak e outras proteínas quinases
CA2673472A1 (en) 2006-12-21 2008-07-03 Vertex Pharmaceuticals Incorporated 5-cyan0-4- (pyrrolo) [2, 3b] pyridine-3-yl) -pyrimidine derivatives useful as protein kinase inhibitors
KR101702609B1 (ko) 2009-06-17 2017-02-03 버텍스 파마슈티칼스 인코포레이티드 인플루엔자 바이러스 복제의 억제제
EP2651940A1 (en) 2010-12-16 2013-10-23 Vertex Pharmaceuticals Incorporated Inhibitors of influenza viruses replication
UA118010C2 (uk) 2011-08-01 2018-11-12 Вертекс Фармасьютікалз Інкорпорейтед Інгібітори реплікації вірусів грипу
CA2930103A1 (en) 2013-11-13 2015-05-21 Vertex Pharmaceuticals Incorporated Inhibitors of influenza viruses replication
EP3421468B1 (en) 2013-11-13 2020-11-04 Vertex Pharmaceuticals Incorporated Methods of preparing inhibitors of influenza viruses replication
JP6857617B2 (ja) 2015-05-13 2021-04-14 バーテックス ファーマシューティカルズ インコーポレイテッドＶｅｒｔｅｘ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｃｏｒｐｏｒａｔｅｄ インフルエンザウイルスの複製の阻害剤
WO2016183116A1 (en) 2015-05-13 2016-11-17 Vertex Pharmaceuticals Incorporated Methods of preparing inhibitors of influenza viruses replication

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2075057A1 (en) 1990-03-15 1991-09-16 Pharmacia & Upjohn Company Llc Therapeutically useful heterocyclic indole compounds
DE4135474A1 (de) 1991-10-28 1993-04-29 Bayer Ag 2-aminomethyl-chromane
DE4140540A1 (de) 1991-12-09 1993-06-17 Bayer Ag Neue azaheterocyclylmethyl-chromane
US5741789A (en) 1995-01-17 1998-04-21 Eli Lilly And Company Compounds having effects on serotonin-related systems
GB9526495D0 (en) 1995-12-23 1996-02-28 Knoll Ag Therapeutic agents
US5869490A (en) 1996-10-15 1999-02-09 American Home Products Corporation Azaheterocyclymethyl derivatives of 2,3,8,9-tetrahydro-7h-1,4-dioxino (2,3-e) indol-8-one
DE69722020T2 (de) 1996-10-15 2004-01-22 Wyeth Azaheterocyclylmethyl-derivate von 2,3,8,9-tetrahydro-7h-1,4-dioxino[2,3-e]indol-8-on
GB9627005D0 (en) * 1996-12-27 1997-02-12 Knoll Ag Therapeutic agents
GB9704948D0 (en) * 1997-03-11 1997-04-30 Knoll Ag Therapeutic agents
AU8743098A (en) 1997-08-22 1999-03-16 Eli Lilly And Company Limited Benzothiadiazinyl-indole derivatives and their use as serotonin receptor ligands
US6458802B1 (en) * 2001-03-14 2002-10-01 Wyeth Antidepressant azaheterocyclymethyl derivatives of 2,3-dihydro-1,4-dioxino [2,3-f]quinoline

Also Published As

Publication number Publication date
MXPA03009829A (es) 2005-03-07
DK1392700T3 (da) 2004-10-25
JP2004528352A (ja) 2004-09-16
EP1392700A1 (en) 2004-03-03
DE60201447T2 (de) 2006-02-23
CN1256337C (zh) 2006-05-17
EP1392700B1 (en) 2004-09-29
BR0209407A (pt) 2004-07-06
US20030109562A1 (en) 2003-06-12
US20020183354A1 (en) 2002-12-05
CA2445859A1 (en) 2002-11-07
ES2225798T3 (es) 2005-03-16
WO2002088140A1 (en) 2002-11-07
US6613913B2 (en) 2003-09-02
ATE277934T1 (de) 2004-10-15
US6525075B2 (en) 2003-02-25
CN1503799A (zh) 2004-06-09
DE60201447D1 (de) 2004-11-04
PT1392700E (pt) 2004-12-31

Similar Documents

Publication Publication Date Title
GB0004128D0 (en) Novel compounds
IS6658A (is) Ný efnasambönd
PA8539901A1 (es) Novedosa sal de succinato de o-desmetil-venlafaxina
MXPA03007140A (es) Derivados de carbolina.
HUP0102160A2 (hu) Alfa-keto-enamin-származékok alkalmazása alkotórészként
SG146442A1 (en) Sulphonamide derivatives, their preparation and use as medicaments
BR0109272A (pt) Agentes conjugados terapêuticos de ácido poliglutâmico, métodos para suas preparações e usos
ATE231872T1 (de) Thiazolopyrimidinderivate
IS6520A (is) Ný efnasambönd
PT1453512E (pt) Derivados de acetileno tendo actividade antagonistica do mglur 5
DE60209929D1 (de) Succinate des 5,8,14-triazatetracycloä10.3.1.0 2,11 .0 4,9 ü-hexadeca-2(11),3,5,7,9,-pentaens und pharmazeutische zusammensetzungen
TR200402753T4 (tr) 7,8-Dihidro-1,6,9-trioksa-3-aza-siklopenta[a]naftalen'in antidepresan azaheterosiklmetil türevleri.
ATE300541T1 (de) Pyrazolopyridinderivate
TR200200359T2 (tr) Cgrp Antagonist'lerinin ve cgrp-release (Gevşeme)-Engelleyici Menopoza Bağlı Deri Kızarıklıklarında Kullanılması
SE0101932D0 (sv) Pharmaceutical combinations
DK1097173T3 (da) Anvendelse af peptider af IL-2 og derivater deraf som terapeutiske midler
HUP0303463A1 (hu) Dimer izoflavonok
MY135916A (en) Use of certain affinity nmda antagonists as antidepressants
SE0102716D0 (sv) Novel compounds
MY118345A (en) Repinotan kit
DK1330258T3 (da) Kahalalid F-formulering
TR200402070T4 (tr) Siklobüten-dion türevleri ve bunların damar sertliği tedavisinde kullanımı
TNSN04034A1 (en) Combined preparations, containing 1,4-benzothiepine-1,1-dioxide derivatives and other active substances, and the use thereof
DE60202590D1 (de) 2h-1-benzopyran-derivate, prozesse zu ihrer herstellung und pharmazeutische zusammensetzungen
ATE311429T1 (de) 8-tetradecenal als duft- oder aromastoff