CY1113560T1 - Αζαϊνδολια χρησιμα ως αναστολεις των jak και αλλων πρωτεϊνικων κινασων - Google Patents
Αζαϊνδολια χρησιμα ως αναστολεις των jak και αλλων πρωτεϊνικων κινασωνInfo
- Publication number
- CY1113560T1 CY1113560T1 CY20131100082T CY131100082T CY1113560T1 CY 1113560 T1 CY1113560 T1 CY 1113560T1 CY 20131100082 T CY20131100082 T CY 20131100082T CY 131100082 T CY131100082 T CY 131100082T CY 1113560 T1 CY1113560 T1 CY 1113560T1
- Authority
- CY
- Cyprus
- Prior art keywords
- protein kinases
- azandolia
- jak
- suspensions
- useful
- Prior art date
Links
- 102000001253 Protein Kinase Human genes 0.000 title abstract 2
- 108060006633 protein kinase Proteins 0.000 title abstract 2
- 239000000725 suspension Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 239000003112 inhibitor Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
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- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
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- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
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Abstract
Η παρούσα εφεύρεση αναφέρεται σε ενώσεις του τύπου (I), οι οποίες είναι αναστολείς των πρωτεϊνικών κινασών. Η εφεύρεση παρέχει επίσης φαρμακευτικές συνθέσεις οι οποίες περιέχουν τις ενώσεις της εφεύρεσης και μεθόδους χρήσης των συνθέσεων στη θεραπεία ποικίλλων παθήσεων.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
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US55750304P | 2004-03-30 | 2004-03-30 | |
US62559904P | 2004-11-05 | 2004-11-05 | |
EP10182365A EP2332940B1 (en) | 2004-03-30 | 2005-03-30 | Azaindoles useful as inhibitors of JAK and other protein kinases |
Publications (1)
Publication Number | Publication Date |
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CY1113560T1 true CY1113560T1 (el) | 2016-06-22 |
Family
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Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
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CY20111100709T CY1111716T1 (el) | 2004-03-30 | 2011-07-20 | Αζαϊνδολια χρησιμα ως αναστολεις των jak και αλλων πρωτεϊνικων κινασων |
CY20131100082T CY1113560T1 (el) | 2004-03-30 | 2013-01-30 | Αζαϊνδολια χρησιμα ως αναστολεις των jak και αλλων πρωτεϊνικων κινασων |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
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CY20111100709T CY1111716T1 (el) | 2004-03-30 | 2011-07-20 | Αζαϊνδολια χρησιμα ως αναστολεις των jak και αλλων πρωτεϊνικων κινασων |
Country Status (27)
Country | Link |
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US (6) | US7507826B2 (el) |
EP (4) | EP2311837B1 (el) |
JP (5) | JP4937112B2 (el) |
KR (3) | KR101216372B1 (el) |
CN (3) | CN101676285A (el) |
AR (2) | AR048454A1 (el) |
AT (1) | ATE508129T1 (el) |
AU (3) | AU2005228904C1 (el) |
BR (1) | BRPI0509369B1 (el) |
CA (1) | CA2560454C (el) |
CY (2) | CY1111716T1 (el) |
DE (1) | DE602005027825D1 (el) |
DK (2) | DK1730146T3 (el) |
ES (2) | ES2364340T3 (el) |
HK (2) | HK1098471A1 (el) |
HR (1) | HRP20110566T8 (el) |
IL (2) | IL177807A (el) |
MX (1) | MXPA06011327A (el) |
NO (2) | NO340403B1 (el) |
NZ (2) | NZ549880A (el) |
PL (2) | PL1730146T3 (el) |
PT (2) | PT2332940E (el) |
RS (1) | RS51830B (el) |
RU (2) | RU2403252C2 (el) |
SI (1) | SI1730146T1 (el) |
TW (3) | TWI465437B (el) |
WO (1) | WO2005095400A1 (el) |
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