BR0209343A - Antidepressivos de azaheterociclilmetila derivados de [1,4]-benzodioxanos oxaheterociclo-fundidos; métodos de tratamento usando tais compostos; processo para prepará-los - Google Patents
Antidepressivos de azaheterociclilmetila derivados de [1,4]-benzodioxanos oxaheterociclo-fundidos; métodos de tratamento usando tais compostos; processo para prepará-losInfo
- Publication number
- BR0209343A BR0209343A BR0209343-0A BR0209343A BR0209343A BR 0209343 A BR0209343 A BR 0209343A BR 0209343 A BR0209343 A BR 0209343A BR 0209343 A BR0209343 A BR 0209343A
- Authority
- BR
- Brazil
- Prior art keywords
- compounds
- treatment
- oxaheterocyclo
- azaheterocyclylmethyl
- benzodioxanes
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Addiction (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Child & Adolescent Psychology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Gynecology & Obstetrics (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
Abstract
"ANTIDEPRESSIVOS DE AZAHETEROCICLILMETILA DERIVADOS DE [1,4]-BENZODIOXANOS OXAHETEROCICLO-FUNDIDOS; MéTODO DE TRATAMENTO USANDO TAIS COMPOSTOS; PROCESSO PARA PREPARá-LOS". Compostos da fórmula úteis para o tratamento de depressão tal como distúrbios compulsiva obsessiva, ataques de pânico, distúrbios de ansiedade generalizada, distúrbios de ansiedade social, disfunção sexual, distúrbios alimentares, obesidade, distúrbios de vício provocadas por abuso de etanol ou cocaína e doenças relacionadas.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US28656901P | 2001-04-26 | 2001-04-26 | |
PCT/US2002/012831 WO2002088135A1 (en) | 2001-04-26 | 2002-04-24 | Antidepressant azaheterocyclylmethyl derivatives of oxaheterocycle-fused-[1,4]-benzodioxans |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0209343A true BR0209343A (pt) | 2004-06-15 |
Family
ID=23099201
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0209343-0A BR0209343A (pt) | 2001-04-26 | 2002-04-24 | Antidepressivos de azaheterociclilmetila derivados de [1,4]-benzodioxanos oxaheterociclo-fundidos; métodos de tratamento usando tais compostos; processo para prepará-los |
Country Status (12)
Country | Link |
---|---|
US (1) | US6552049B2 (pt) |
EP (1) | EP1381613B1 (pt) |
JP (1) | JP2004532236A (pt) |
CN (1) | CN1503798A (pt) |
AT (1) | ATE279415T1 (pt) |
BR (1) | BR0209343A (pt) |
CA (1) | CA2445543A1 (pt) |
DE (1) | DE60201590T2 (pt) |
DK (1) | DK1381613T3 (pt) |
ES (1) | ES2229138T3 (pt) |
MX (1) | MXPA03009825A (pt) |
WO (1) | WO2002088135A1 (pt) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6706736B2 (en) * | 2001-04-26 | 2004-03-16 | Wyeth | Antidepressant azaheterocyclylmethyl derivatives of oxaheterocycle-fused-[1,4]-benzodioxans |
US6911445B2 (en) | 2002-09-12 | 2005-06-28 | Wyeth | Antidepressant cycloalkylamine derivatives of heterocycle-fused benzodioxans |
US7507826B2 (en) | 2004-03-30 | 2009-03-24 | Vertex Pharmaceuticals Incorporated | Azaindoles useful as inhibitors of JAK and other protein kinases |
JP2005314260A (ja) * | 2004-04-28 | 2005-11-10 | Japan Science & Technology Agency | フラボンc配糖体の製法 |
BRPI0608353A2 (pt) * | 2005-02-17 | 2009-12-01 | Wyeth Corp | derivados de indol, benzotiofeno, benzofurano e indeno cicloalquilfundidos |
MX2009006700A (es) | 2006-12-21 | 2009-06-30 | Vertex Pharma | Derivados de 5-ciano-4-(pirolo)[2,3b]piridina-3-il)-pirimidinas utiles como inhibidores de proteina-cinasas. |
HUE031048T2 (en) | 2009-06-17 | 2017-06-28 | Vertex Pharma | Influenza virus replication inhibitors |
CN103492381A (zh) | 2010-12-16 | 2014-01-01 | 沃泰克斯药物股份有限公司 | 流感病毒复制的抑制剂 |
UA118010C2 (uk) | 2011-08-01 | 2018-11-12 | Вертекс Фармасьютікалз Інкорпорейтед | Інгібітори реплікації вірусів грипу |
RS57541B1 (sr) | 2013-11-13 | 2018-10-31 | Vertex Pharma | Postupci za pripremu inhibitora replikacije virusa gripa |
CN105849100B (zh) | 2013-11-13 | 2019-07-16 | 沃泰克斯药物股份有限公司 | 流感病毒复制抑制剂 |
WO2016183120A1 (en) | 2015-05-13 | 2016-11-17 | Vertex Pharmaceuticals Incorporated | Inhibitors of influenza viruses replication |
JP6704416B2 (ja) | 2015-05-13 | 2020-06-03 | バーテックス ファーマシューティカルズ インコーポレイテッドVertex Pharmaceuticals Incorporated | インフルエンザウイルスの複製の阻害剤を調製する方法 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4135474A1 (de) | 1991-10-28 | 1993-04-29 | Bayer Ag | 2-aminomethyl-chromane |
DE4140540A1 (de) | 1991-12-09 | 1993-06-17 | Bayer Ag | Neue azaheterocyclylmethyl-chromane |
WO1995005383A1 (en) | 1993-08-19 | 1995-02-23 | Janssen Pharmaceutica N.V. | Vasocontrictive dihydrobenzopyran derivatives |
US5741789A (en) | 1995-01-17 | 1998-04-21 | Eli Lilly And Company | Compounds having effects on serotonin-related systems |
GB9526495D0 (en) | 1995-12-23 | 1996-02-28 | Knoll Ag | Therapeutic agents |
WO1998016530A1 (en) | 1996-10-15 | 1998-04-23 | American Home Products Corporation | AZAHETEROCYCLYMETHYL DERIVATIVES OF 2,3,8,9-TETRAHYDRO-7H-1,4-DIOXINO[2,3-e]INDOL-8-ONE |
US5869490A (en) | 1996-10-15 | 1999-02-09 | American Home Products Corporation | Azaheterocyclymethyl derivatives of 2,3,8,9-tetrahydro-7h-1,4-dioxino (2,3-e) indol-8-one |
GB9627005D0 (en) * | 1996-12-27 | 1997-02-12 | Knoll Ag | Therapeutic agents |
GB9704948D0 (en) * | 1997-03-11 | 1997-04-30 | Knoll Ag | Therapeutic agents |
AU8743098A (en) | 1997-08-22 | 1999-03-16 | Eli Lilly And Company Limited | Benzothiadiazinyl-indole derivatives and their use as serotonin receptor ligands |
US6458802B1 (en) * | 2001-03-14 | 2002-10-01 | Wyeth | Antidepressant azaheterocyclymethyl derivatives of 2,3-dihydro-1,4-dioxino [2,3-f]quinoline |
-
2002
- 2002-04-24 ES ES02728947T patent/ES2229138T3/es not_active Expired - Lifetime
- 2002-04-24 CA CA002445543A patent/CA2445543A1/en not_active Abandoned
- 2002-04-24 MX MXPA03009825A patent/MXPA03009825A/es unknown
- 2002-04-24 US US10/131,340 patent/US6552049B2/en not_active Expired - Fee Related
- 2002-04-24 AT AT02728947T patent/ATE279415T1/de not_active IP Right Cessation
- 2002-04-24 BR BR0209343-0A patent/BR0209343A/pt not_active Application Discontinuation
- 2002-04-24 DE DE60201590T patent/DE60201590T2/de not_active Expired - Fee Related
- 2002-04-24 EP EP02728947A patent/EP1381613B1/en not_active Expired - Lifetime
- 2002-04-24 WO PCT/US2002/012831 patent/WO2002088135A1/en active IP Right Grant
- 2002-04-24 DK DK02728947T patent/DK1381613T3/da active
- 2002-04-24 CN CNA028086473A patent/CN1503798A/zh active Pending
- 2002-04-24 JP JP2002585434A patent/JP2004532236A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
ES2229138T3 (es) | 2005-04-16 |
US20020183353A1 (en) | 2002-12-05 |
CA2445543A1 (en) | 2002-11-07 |
WO2002088135A1 (en) | 2002-11-07 |
ATE279415T1 (de) | 2004-10-15 |
EP1381613A1 (en) | 2004-01-21 |
DE60201590T2 (de) | 2005-02-17 |
CN1503798A (zh) | 2004-06-09 |
JP2004532236A (ja) | 2004-10-21 |
MXPA03009825A (es) | 2005-03-07 |
EP1381613B1 (en) | 2004-10-13 |
DK1381613T3 (da) | 2005-01-24 |
DE60201590D1 (de) | 2004-11-18 |
US6552049B2 (en) | 2003-04-22 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] |