BR0209336A - Antidepressivos de indoltetrahidropiridinas derivados de 2,3-dihidro-7h-[1,4]dioxino[2,3]indol, método de tratamento usando tais compostos e processo para prepará-los - Google Patents

Antidepressivos de indoltetrahidropiridinas derivados de 2,3-dihidro-7h-[1,4]dioxino[2,3]indol, método de tratamento usando tais compostos e processo para prepará-los

Info

Publication number
BR0209336A
BR0209336A BR0209336-7A BR0209336A BR0209336A BR 0209336 A BR0209336 A BR 0209336A BR 0209336 A BR0209336 A BR 0209336A BR 0209336 A BR0209336 A BR 0209336A
Authority
BR
Brazil
Prior art keywords
compounds
treatment
dihydro
indoltetrahydropyridine
antidepressants
Prior art date
Application number
BR0209336-7A
Other languages
English (en)
Inventor
Gary Paul Stack
Megan Tran
Byron Abel Bravo
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of BR0209336A publication Critical patent/BR0209336A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Addiction (AREA)
  • Cardiology (AREA)
  • Psychiatry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Gynecology & Obstetrics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)

Abstract

"ANTIDEPRESSIVOS DE INDOLTETRAHIDROPIRIDINAS DERIVADOS DE 2,3-DIHIDRO-7H-[1,4]DIOXINO[2,3-e]INDOL, MéTODO DE TRATAMENTO USANDO TAIS COMPOSTOS E PROCESSO PARA PREPARá-LOS". Compostos de fórmula (I) são úteis no tratamento de desordens do sistema nervoso central incluindo depressão, desordem obsessiva compulsiva, ataques de pânico, desordem de ansiedade generalizada, disfunções sexuais, desordens de alimentação e desordens de vício provocado por abuso de etanol ou cocaína.
BR0209336-7A 2001-04-26 2002-04-25 Antidepressivos de indoltetrahidropiridinas derivados de 2,3-dihidro-7h-[1,4]dioxino[2,3]indol, método de tratamento usando tais compostos e processo para prepará-los BR0209336A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28657501P 2001-04-26 2001-04-26
PCT/US2002/013118 WO2002088146A2 (en) 2001-04-26 2002-04-25 ANTIDEPRESSANT INDOLETETRAHYDROPYRIDINE DERIVATIVES OF 2,3-DIHYDRO-7H-[1,4]DIOXINO[2,3-e]INDOLE

Publications (1)

Publication Number Publication Date
BR0209336A true BR0209336A (pt) 2004-06-15

Family

ID=23099224

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0209336-7A BR0209336A (pt) 2001-04-26 2002-04-25 Antidepressivos de indoltetrahidropiridinas derivados de 2,3-dihidro-7h-[1,4]dioxino[2,3]indol, método de tratamento usando tais compostos e processo para prepará-los

Country Status (14)

Country Link
US (1) US6593350B2 (pt)
EP (1) EP1381615B1 (pt)
JP (1) JP2004533437A (pt)
CN (1) CN1267438C (pt)
AT (1) ATE279418T1 (pt)
AU (1) AU2002259010A1 (pt)
BR (1) BR0209336A (pt)
CA (1) CA2445583A1 (pt)
DE (1) DE60201592T2 (pt)
DK (1) DK1381615T3 (pt)
ES (1) ES2230490T3 (pt)
MX (1) MXPA03009739A (pt)
PT (1) PT1381615E (pt)
WO (1) WO2002088146A2 (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6939877B2 (en) * 2002-09-12 2005-09-06 Wyeth Antidepressant piperidine derivatives of heterocycle-fused benzodioxans
WO2004082686A2 (en) * 2003-03-13 2004-09-30 Dynogen Pharmaceuticals, Inc. Use of compounds with combined 5-ht1a and ssri activities to treat sexual dysfunction
CN100402534C (zh) * 2006-11-09 2008-07-16 东南大学 一种三环类化合物及其在制药中的应用
EP3141252B8 (en) 2009-06-17 2019-03-13 Vertex Pharmaceuticals Incorporated Inhibitors of influenza viruses replication
CN103492381A (zh) 2010-12-16 2014-01-01 沃泰克斯药物股份有限公司 流感病毒复制的抑制剂
CN102178056B (zh) * 2011-05-05 2012-08-08 王宏雁 二氢吡啶包合物
UA118010C2 (uk) 2011-08-01 2018-11-12 Вертекс Фармасьютікалз Інкорпорейтед Інгібітори реплікації вірусів грипу
EP3851437A3 (en) 2013-11-13 2021-11-03 Vertex Pharmaceuticals Incorporated Methods of preparing 1h-pyrrolo[2,3-b]pyridine derivates
AU2014348840B2 (en) 2013-11-13 2019-06-06 Vertex Pharmaceuticals Incorporated Inhibitors of influenza viruses replication
WO2016183116A1 (en) 2015-05-13 2016-11-17 Vertex Pharmaceuticals Incorporated Methods of preparing inhibitors of influenza viruses replication
WO2016183120A1 (en) 2015-05-13 2016-11-17 Vertex Pharmaceuticals Incorporated Inhibitors of influenza viruses replication

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991013872A1 (en) 1990-03-15 1991-09-19 The Upjohn Company Therapeutically useful heterocyclic indole compounds
DE4135474A1 (de) 1991-10-28 1993-04-29 Bayer Ag 2-aminomethyl-chromane
DE4140540A1 (de) 1991-12-09 1993-06-17 Bayer Ag Neue azaheterocyclylmethyl-chromane
US5741789A (en) 1995-01-17 1998-04-21 Eli Lilly And Company Compounds having effects on serotonin-related systems
GB9526495D0 (en) 1995-12-23 1996-02-28 Knoll Ag Therapeutic agents
US5869490A (en) 1996-10-15 1999-02-09 American Home Products Corporation Azaheterocyclymethyl derivatives of 2,3,8,9-tetrahydro-7h-1,4-dioxino (2,3-e) indol-8-one
GB9627005D0 (en) 1996-12-27 1997-02-12 Knoll Ag Therapeutic agents
GB9704948D0 (en) 1997-03-11 1997-04-30 Knoll Ag Therapeutic agents
US6458802B1 (en) * 2001-03-14 2002-10-01 Wyeth Antidepressant azaheterocyclymethyl derivatives of 2,3-dihydro-1,4-dioxino [2,3-f]quinoline

Also Published As

Publication number Publication date
EP1381615B1 (en) 2004-10-13
ATE279418T1 (de) 2004-10-15
DK1381615T3 (da) 2004-11-29
PT1381615E (pt) 2005-02-28
CN1503800A (zh) 2004-06-09
CA2445583A1 (en) 2002-11-07
ES2230490T3 (es) 2005-05-01
AU2002259010A1 (en) 2002-11-11
DE60201592T2 (de) 2005-02-17
US20020183352A1 (en) 2002-12-05
JP2004533437A (ja) 2004-11-04
DE60201592D1 (de) 2004-11-18
WO2002088146A3 (en) 2003-02-13
MXPA03009739A (es) 2005-03-07
EP1381615A2 (en) 2004-01-21
WO2002088146A2 (en) 2002-11-07
US6593350B2 (en) 2003-07-15
CN1267438C (zh) 2006-08-02

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Legal Events

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B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

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B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2103 DE 26/04/2011.