ATE315390T1 - Zyklische polyamine zur behandlung der thrombozytopenie - Google Patents

Zyklische polyamine zur behandlung der thrombozytopenie

Info

Publication number
ATE315390T1
ATE315390T1 AT99960442T AT99960442T ATE315390T1 AT E315390 T1 ATE315390 T1 AT E315390T1 AT 99960442 T AT99960442 T AT 99960442T AT 99960442 T AT99960442 T AT 99960442T AT E315390 T1 ATE315390 T1 AT E315390T1
Authority
AT
Austria
Prior art keywords
thrombocytopenia
treatment
cyclic polyamines
mammal
invented
Prior art date
Application number
AT99960442T
Other languages
English (en)
Inventor
Juan I Luengo
Peter I Lamb
Original Assignee
Smithkline Beecham Corp
Ligand Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp, Ligand Pharm Inc filed Critical Smithkline Beecham Corp
Application granted granted Critical
Publication of ATE315390T1 publication Critical patent/ATE315390T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT99960442T 1998-11-17 1999-11-17 Zyklische polyamine zur behandlung der thrombozytopenie ATE315390T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10880898P 1998-11-17 1998-11-17

Publications (1)

Publication Number Publication Date
ATE315390T1 true ATE315390T1 (de) 2006-02-15

Family

ID=22324161

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99960442T ATE315390T1 (de) 1998-11-17 1999-11-17 Zyklische polyamine zur behandlung der thrombozytopenie

Country Status (8)

Country Link
US (1) US6498155B1 (de)
EP (1) EP1133291B1 (de)
JP (1) JP2002529502A (de)
AT (1) ATE315390T1 (de)
AU (1) AU1732900A (de)
DE (1) DE69929464T2 (de)
ES (1) ES2257090T3 (de)
WO (1) WO2000028987A1 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6365583B1 (en) * 1999-02-02 2002-04-02 Anormed, Inc. Methods to enhance white blood cell count
AU2001260661A1 (en) 2000-05-30 2001-12-11 Chugai Seiyaku Kabushiki Kaisha Compounds exhibiting thrombopoietin-like activities
ES2398399T3 (es) * 2000-09-29 2013-03-15 Genzyme Corporation Procedimiento para la preparación de poliaminas cíclicas que contienen n nitrógenos en el anillo con n-1 protegidos y sus productos
JP2004520302A (ja) 2000-12-19 2004-07-08 スミスクライン・ビーチャム・コーポレイション トロンボポエチン模倣物
MXPA04000982A (es) 2001-07-31 2004-04-20 Anormed Inc Metodos para movilizar celulas progenitoras/madre.
EP1466912B1 (de) * 2002-01-18 2013-04-24 Astellas Pharma Inc. 2-acylaminothiazolderivat oder salz davon
JP2007530440A (ja) * 2003-05-12 2007-11-01 アフィーマックス・インコーポレイテッド 新規ポリ（エチレングリコール）修飾化合物およびその用途
NZ563042A (en) 2003-05-12 2008-09-26 Affymax Inc Novel spacer moiety for poly(ethylene glycol)-modified peptide-based compounds
US7528104B2 (en) * 2003-05-12 2009-05-05 Affymax, Inc. Peptides that bind to the erythropoietin receptor
AU2005310189A1 (en) * 2004-11-11 2006-06-08 Affymax, Inc. Novel peptides that bind to the erythropoietin receptor
WO2006062685A2 (en) * 2004-11-11 2006-06-15 Affymax, Inc. Novel peptides that bind to the erythropoietin receptor
US7919461B2 (en) 2005-06-03 2011-04-05 Affymax, Inc. Erythropoietin receptor peptide formulations and uses
US7550433B2 (en) 2005-06-03 2009-06-23 Affymax, Inc. Erythropoietin receptor peptide formulations and uses
US8324159B2 (en) * 2005-06-03 2012-12-04 Affymax, Inc. Erythropoietin receptor peptide formulations and uses
US20070203153A1 (en) * 2005-11-08 2007-08-30 Astellas Pharma Inc. Compositions and methods for treating thrombocytopenia
WO2008021283A2 (en) * 2006-08-08 2008-02-21 Akarx, Inc. Compositions and methods for increasing blood platelet levels in humans
US8106154B2 (en) * 2007-01-31 2012-01-31 Affymax, Inc. Nitrogen-based linkers for attaching modifying groups to polypeptides and other macromolecules
CN101481352A (zh) 2008-01-10 2009-07-15 上海恒瑞医药有限公司 双环取代吡唑酮偶氮类衍生物、其制备方法及其在医药上的应用
PE20100362A1 (es) 2008-10-30 2010-05-27 Irm Llc Derivados de purina que expanden las celulas madre hematopoyeticas
CN101921232A (zh) 2009-06-11 2010-12-22 上海恒瑞医药有限公司 双环取代吡唑酮偶氮类衍生物的盐,其制备方法及其在医药上的应用
WO2012102937A2 (en) 2011-01-25 2012-08-02 Irm Llc Compounds that expand hematopoietic stem cells
AU2012347534B2 (en) 2011-12-08 2018-01-25 Fred Hutchinson Cancer Research Center Compositions and methods for enhanced generation of hematopoietic stem/progenitor cells
PL2807165T3 (pl) 2012-01-27 2019-09-30 Université de Montréal Pochodne pirymido[4,5-b]indolu i ich zastosowanie do namnażania hematopoetycznych komórek macierzystych
WO2014125499A1 (en) 2013-02-13 2014-08-21 Natco Pharma Limited Improved and commercially viable process for the preparation of high pure plerixafor base
JP6762233B2 (ja) 2014-04-22 2020-09-30 ウニヴェルシテ ド モントリオールＵｎｉｖｅｒｓｉｔｅ Ｄｅ Ｍｏｎｔｒｅａｌ 化合物および造血幹細胞および／または造血前駆細胞の増大におけるその使用
US10544109B2 (en) 2015-09-02 2020-01-28 Fresenius Kabi Oncology Ltd. Process for the preparation of xylene linked cyclam compounds

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5037804A (en) 1987-09-02 1991-08-06 Daiichi Seiyaku Co., Ltd. Agent for preventing and treating thrombocytopenia
JP2805224B2 (ja) * 1989-01-13 1998-09-30 味の素株式会社 血小板減少症治療剤
GB9126677D0 (en) 1991-12-16 1992-02-12 Johnson Matthey Plc Improvements in chemical compounds
US5932546A (en) * 1996-10-04 1999-08-03 Glaxo Wellcome Inc. Peptides and compounds that bind to the thrombopoietin receptor
WO1999011262A1 (en) 1997-09-02 1999-03-11 Roche Diagnostics Gmbh Mpl-receptor ligands, process for their preparation, medicaments containing them and their use for the treatment and prevention of thrombocytopaenia and anaemia
ES2284217T3 (es) 1997-10-31 2007-11-01 Smithkline Beecham Corporation Complejos metalicos novedosos.
EP1032388A4 (de) 1997-10-31 2002-10-02 Smithkline Beecham Corp Neue metallkomplexe

Also Published As

Publication number Publication date
WO2000028987A1 (en) 2000-05-25
US6498155B1 (en) 2002-12-24
JP2002529502A (ja) 2002-09-10
ES2257090T3 (es) 2006-07-16
DE69929464T2 (de) 2006-09-07
AU1732900A (en) 2000-06-05
EP1133291B1 (de) 2006-01-11
EP1133291A4 (de) 2002-05-02
DE69929464D1 (de) 2006-04-06
EP1133291A1 (de) 2001-09-19

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