CN104059013B8 - 1-芳基-3-氮杂二环[3.1.0]己烷：其制备方法和用于治疗神经精神障碍的用途 - Google Patents

1-芳基-3-氮杂二环[3.1.0]己烷：其制备方法和用于治疗神经精神障碍的用途 Download PDF

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CN104059013B8
CN104059013B8 CN201410309301.2A CN201410309301A CN104059013B8 CN 104059013 B8 CN104059013 B8 CN 104059013B8 CN 201410309301 A CN201410309301 A CN 201410309301A CN 104059013 B8 CN104059013 B8 CN 104059013B8
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azabicyclo
hexane
aryl
treating
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CN104059013B (zh
CN104059013A (zh
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P·斯科尔尼克
陈正明
A·巴齐尔
J·W·埃普斯坦
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Otsuka America Pharmaceutical Inc
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Abstract

本发明提供了新的多取代的1-芳基-3-氮杂二环[3.1.0]己烷，以及用于制备这些化合物的相关工艺方法和中间体，还有应用这些化合物以治疗和/或预防中枢神经系统(CNS)障碍的方法和组合物，所述中枢神经系统(CNS)障碍包括抑郁和焦虑。
CN201410309301.2A 2005-07-27 2006-07-25 1-芳基-3-氮杂二环[3.1.0]己烷：其制备方法和用于治疗神经精神障碍的用途 Active CN104059013B8 (zh)

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US70336405P 2005-07-27 2005-07-27
US60/703,364 2005-07-27
CNA2006800354264A CN101272781A (zh) 2005-07-27 2006-07-25 新的1-芳基-3-氮杂二环[3.1.0]己烷：其制备方法和用于治疗神经精神障碍的用途
US11/493,431 2006-07-25
US11/493,431 US20070082940A1 (en) 2005-07-27 2006-07-25 Novel 1-aryl-3-azabicyclo[3.1.0]hexanes: preparation and use to treat neuropsychiatric disorders

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CN104059013B CN104059013B (zh) 2016-06-22
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CN201410309301.2A Active CN104059013B8 (zh) 2005-07-27 2006-07-25 1-芳基-3-氮杂二环[3.1.0]己烷：其制备方法和用于治疗神经精神障碍的用途

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AU (1) AU2006275870B2 (zh)
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