CY1112580T1 - Συνθεσεις και μεθοδοι για βελτιωμενη απελευθερωση υδροφοβων θεραπευτικων παραγοντων - Google Patents

Συνθεσεις και μεθοδοι για βελτιωμενη απελευθερωση υδροφοβων θεραπευτικων παραγοντων

Info

Publication number
CY1112580T1
CY1112580T1 CY20121100250T CY121100250T CY1112580T1 CY 1112580 T1 CY1112580 T1 CY 1112580T1 CY 20121100250 T CY20121100250 T CY 20121100250T CY 121100250 T CY121100250 T CY 121100250T CY 1112580 T1 CY1112580 T1 CY 1112580T1
Authority
CY
Cyprus
Prior art keywords
compositions
therapeutic agents
hydrophone
methods
improved determination
Prior art date
Application number
CY20121100250T
Other languages
English (en)
Inventor
Mahesh V Patel
Feng-Jing Chen
Original Assignee
Lipocine Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22981541&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1112580(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lipocine Inc. filed Critical Lipocine Inc.
Publication of CY1112580T1 publication Critical patent/CY1112580T1/el

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/06—Antiabortive agents; Labour repressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/26—Androgens

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Nanotechnology (AREA)
  • Endocrinology (AREA)
  • Molecular Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Reproductive Health (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Diabetes (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Transplantation (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Η παρούσα εφεύρεση σχετίζεται με ελεύθερες-τριγλυκεριδίων φαρμακευτικές συνθέσεις για απελευθέρωση υδρόφοβων θεραπευτικών παραγόντων. Οι συνθέσεις της παρούσας εφεύρεσης συμπεριλαμβάνουν έναν υδρόφοβο θεραπευτικό παράγοντα και μια ουσία-φορέα, όπου η ουσία-φορέας σχηματίζεται από έναν συνδυασμό ενός υδρόφιλου επαφανειοδραστικού και ενός υδρόφοβου επιφανειοδραστικού. Κατά την αραίωση με έναν υδατικό διαλύτη, η σύνθεση σχηματίζει μια διαυγή, υδατική διασπορά των επιφανειοδραστικών περιέχοντας τον θεραπευτικό παράγοντα. Η εφεύρεση παρέχει επίσης μεθόδους αγωγής με υδρόφοβους θεραπευτικούς παράγοντες χρησιμοποιώντας αυτές τις συνθέσεις.
CY20121100250T 1999-02-26 2012-03-12 Συνθεσεις και μεθοδοι για βελτιωμενη απελευθερωση υδροφοβων θεραπευτικων παραγοντων CY1112580T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/258,654 US6294192B1 (en) 1999-02-26 1999-02-26 Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents
EP00901394A EP1158959B1 (en) 1999-02-26 2000-01-05 Compositions and methods for improved delivery of hydrophobic therapeutic agents

Publications (1)

Publication Number Publication Date
CY1112580T1 true CY1112580T1 (el) 2016-02-10

Family

ID=22981541

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20121100250T CY1112580T1 (el) 1999-02-26 2012-03-12 Συνθεσεις και μεθοδοι για βελτιωμενη απελευθερωση υδροφοβων θεραπευτικων παραγοντων

Country Status (12)

Country Link
US (2) US6294192B1 (el)
EP (2) EP1158959B1 (el)
JP (2) JP2002537317A (el)
AT (1) ATE537812T1 (el)
AU (1) AU771659B2 (el)
CA (1) CA2365536C (el)
CY (1) CY1112580T1 (el)
DK (1) DK1158959T3 (el)
ES (1) ES2379626T3 (el)
NZ (1) NZ513810A (el)
PT (1) PT1158959E (el)
WO (1) WO2000050007A1 (el)

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EP1158959A4 (en) 2004-12-08
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NZ513810A (en) 2004-02-27
DK1158959T3 (da) 2012-03-19
WO2000050007A1 (en) 2000-08-31
JP2012006931A (ja) 2012-01-12
US6451339B2 (en) 2002-09-17
AU771659B2 (en) 2004-04-01
US20020012680A1 (en) 2002-01-31
US6294192B1 (en) 2001-09-25
EP1158959A1 (en) 2001-12-05
JP2002537317A (ja) 2002-11-05
ATE537812T1 (de) 2012-01-15
ES2379626T3 (es) 2012-04-30
CA2365536C (en) 2012-05-15
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AU2224200A (en) 2000-09-14
CA2365536A1 (en) 2000-08-31

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