CR20160102A - Formas de dosificación de liberación prolongada para un inhibidor de jak 1 - Google Patents

Formas de dosificación de liberación prolongada para un inhibidor de jak 1

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Publication number
CR20160102A
CR20160102A CR20160102A CR20160102A CR20160102A CR 20160102 A CR20160102 A CR 20160102A CR 20160102 A CR20160102 A CR 20160102A CR 20160102 A CR20160102 A CR 20160102A CR 20160102 A CR20160102 A CR 20160102A
Authority
CR
Costa Rica
Prior art keywords
dosage forms
release dosage
prolonged release
jak inhibitor
prolonged
Prior art date
Application number
CR20160102A
Other languages
English (en)
Inventor
Krishnaswamy Yeleswaram
Bhavnish Parikh
Dilip P Modi
Trupti Sheth
Original Assignee
Incyte Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Corp filed Critical Incyte Corp
Publication of CR20160102A publication Critical patent/CR20160102A/es

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
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    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
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    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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    • A61P35/02—Antineoplastic agents specific for leukemia
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
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    • A61P37/00—Drugs for immunological or allergic disorders
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
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    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
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    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
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  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Neurology (AREA)
  • Dermatology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Endocrinology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Inorganic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychiatry (AREA)
  • Emergency Medicine (AREA)
  • Transplantation (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Cardiology (AREA)
  • Oncology (AREA)

Abstract

La presente invención se refiere a formas de dosificación de liberación prolongada que comprenden {1-{1-[3-fluoro-2-(trifluorometil)isonicotinoil]piperidin-4-il}-3-[4-(7H-5 pirrolo[2,3-d]pirimidin-4-il)-1H-pirazol-1-il]azetidin-3-il}acetonitrilo o una sal farmacéuticamente aceptable de este y dosis y métodos relacionadas con estas.
CR20160102A 2013-08-07 2016-03-01 Formas de dosificación de liberación prolongada para un inhibidor de jak 1 CR20160102A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361863325P 2013-08-07 2013-08-07
US201361913066P 2013-12-06 2013-12-06
PCT/US2014/049940 WO2015021153A1 (en) 2013-08-07 2014-08-06 Sustained release dosage forms for a jak1 inhibitor

Publications (1)

Publication Number Publication Date
CR20160102A true CR20160102A (es) 2016-07-28

Family

ID=51383933

Family Applications (3)

Application Number Title Priority Date Filing Date
CR20230316A CR20230316A (es) 2013-08-07 2014-08-06 FORMAS DE DOSIFICACION DE LIBERACION PROLONGADA PARA UN INHIBIDOR DE JAK 1 (divisional 2019-343)
CR20190343A CR20190343A (es) 2013-08-07 2014-08-06 FORMAS DE DOSIFICACIÓN DE LIBERACIÓN PROLONGADA PARA UN INHIBIDOR DE JAK 1 (Divisional de Exp: 2016-0102)
CR20160102A CR20160102A (es) 2013-08-07 2016-03-01 Formas de dosificación de liberación prolongada para un inhibidor de jak 1

Family Applications Before (2)

Application Number Title Priority Date Filing Date
CR20230316A CR20230316A (es) 2013-08-07 2014-08-06 FORMAS DE DOSIFICACION DE LIBERACION PROLONGADA PARA UN INHIBIDOR DE JAK 1 (divisional 2019-343)
CR20190343A CR20190343A (es) 2013-08-07 2014-08-06 FORMAS DE DOSIFICACIÓN DE LIBERACIÓN PROLONGADA PARA UN INHIBIDOR DE JAK 1 (Divisional de Exp: 2016-0102)

Country Status (30)

Country Link
US (4) US9655854B2 (es)
EP (2) EP3721873A1 (es)
JP (5) JP6334700B2 (es)
KR (3) KR20220103810A (es)
CN (3) CN116036089A (es)
AU (3) AU2014305989B2 (es)
BR (1) BR122020001831A8 (es)
CA (2) CA2920108C (es)
CL (1) CL2016000292A1 (es)
CR (3) CR20230316A (es)
CY (1) CY1123314T1 (es)
DK (1) DK3030227T3 (es)
EA (1) EA201690357A1 (es)
ES (1) ES2792549T3 (es)
HR (1) HRP20200955T1 (es)
HU (1) HUE049345T2 (es)
IL (2) IL277554B2 (es)
LT (1) LT3030227T (es)
MX (2) MX2016001639A (es)
MY (1) MY195091A (es)
PE (2) PE20160223A1 (es)
PH (3) PH12016500243B1 (es)
PL (1) PL3030227T3 (es)
PT (1) PT3030227T (es)
RS (1) RS60469B1 (es)
SG (3) SG11201600815WA (es)
SI (1) SI3030227T1 (es)
TW (3) TWI789516B (es)
UA (1) UA120499C2 (es)
WO (1) WO2015021153A1 (es)

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