CN117736209A - Pi3k抑制剂的盐及其制备方法 - Google Patents

Pi3k抑制剂的盐及其制备方法 Download PDF

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Publication number
CN117736209A
CN117736209A CN202311505572.0A CN202311505572A CN117736209A CN 117736209 A CN117736209 A CN 117736209A CN 202311505572 A CN202311505572 A CN 202311505572A CN 117736209 A CN117736209 A CN 117736209A
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compound
formula
salt
reaction
chloro
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CN202311505572.0A
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Chinese (zh)
Inventor
L·乔
L·翁
C·E·史
D·梅洛尼
林启彦
M·夏
V·谢里夫
W·弗列茨
Z·贾
Y·潘
P·刘
T-Y·岳
J·周
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Incyte Corp
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Incyte Corp
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=55854770&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN117736209(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Incyte Corp filed Critical Incyte Corp
Publication of CN117736209A publication Critical patent/CN117736209A/zh
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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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  • Ophthalmology & Optometry (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
CN202311505572.0A 2015-02-27 2016-02-26 Pi3k抑制剂的盐及其制备方法 Pending CN117736209A (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201562121697P 2015-02-27 2015-02-27
US62/121,697 2015-02-27
PCT/US2016/019741 WO2016138363A1 (en) 2015-02-27 2016-02-26 Salts of pi3k inhibitor and processes for their preparation
CN201680011760.XA CN107580597A (zh) 2015-02-27 2016-02-26 Pi3k抑制剂的盐及其制备方法

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN201680011760.XA Division CN107580597A (zh) 2015-02-27 2016-02-26 Pi3k抑制剂的盐及其制备方法

Publications (1)

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CN117736209A true CN117736209A (zh) 2024-03-22

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ID=55854770

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Application Number Title Priority Date Filing Date
CN202311505572.0A Pending CN117736209A (zh) 2015-02-27 2016-02-26 Pi3k抑制剂的盐及其制备方法
CN202311539089.4A Pending CN117800973A (zh) 2015-02-27 2016-02-26 Pi3k抑制剂的盐及其制备方法
CN201680011760.XA Withdrawn CN107580597A (zh) 2015-02-27 2016-02-26 Pi3k抑制剂的盐及其制备方法
CN202311519531.7A Pending CN117777139A (zh) 2015-02-27 2016-02-26 Pi3k抑制剂的盐及其制备方法

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Application Number Title Priority Date Filing Date
CN202311539089.4A Pending CN117800973A (zh) 2015-02-27 2016-02-26 Pi3k抑制剂的盐及其制备方法
CN201680011760.XA Withdrawn CN107580597A (zh) 2015-02-27 2016-02-26 Pi3k抑制剂的盐及其制备方法
CN202311519531.7A Pending CN117777139A (zh) 2015-02-27 2016-02-26 Pi3k抑制剂的盐及其制备方法

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CN104945420A (zh) 2009-06-29 2015-09-30 因塞特公司 作为pi3k抑制剂的嘧啶酮类
WO2012087881A1 (en) 2010-12-20 2012-06-28 Incyte Corporation N-(1-(substituted-phenyl)ethyl)-9h-purin-6-amines as pi3k inhibitors
TWI717002B (zh) 2011-09-02 2021-01-21 美商英塞特控股公司 作為pi3k抑制劑之雜環基胺
AR090548A1 (es) 2012-04-02 2014-11-19 Incyte Corp Azaheterociclobencilaminas biciclicas como inhibidores de pi3k
TWI841376B (zh) 2013-03-01 2024-05-01 美商英塞特控股公司 吡唑并嘧啶衍生物治療PI3Kδ相關病症之用途
UA119767C2 (uk) 2014-04-08 2019-08-12 Інсайт Корпорейшн Лікування b-клітинних злоякісних новоутворень із застосуванням комбінації інгібіторів jak та pi3k
WO2015191677A1 (en) 2014-06-11 2015-12-17 Incyte Corporation Bicyclic heteroarylaminoalkyl phenyl derivatives as pi3k inhibitors
HRP20210036T1 (hr) 2015-02-27 2021-03-05 Incyte Corporation Soli inhibitora pi3k i postupci za njihovo dobivanje
US9988401B2 (en) 2015-05-11 2018-06-05 Incyte Corporation Crystalline forms of a PI3K inhibitor
US9732097B2 (en) 2015-05-11 2017-08-15 Incyte Corporation Process for the synthesis of a phosphoinositide 3-kinase inhibitor
CN108137603B (zh) 2015-12-11 2019-10-18 四川科伦博泰生物医药股份有限公司 氮杂环丁烷衍生物、其制备方法及用途
KR20250103804A (ko) 2018-03-08 2025-07-07 인사이트 코포레이션 PI3K-γ 저해제로서의 아미노피라진 다이올 화합물
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