CN111989569A - 免疫细胞类器官共培养物 - Google Patents

免疫细胞类器官共培养物 Download PDF

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Publication number
CN111989569A
CN111989569A CN201880089039.1A CN201880089039A CN111989569A CN 111989569 A CN111989569 A CN 111989569A CN 201880089039 A CN201880089039 A CN 201880089039A CN 111989569 A CN111989569 A CN 111989569A
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cells
tumor
culture
organoid
immune
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Chinese (zh)
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凯·克里施玛尔
约坦·埃拉扎尔·巴-艾普生
约翰尼斯·卡洛斯·克莱维尔斯
西尔维娅·费南德斯-波吉
罗伯特·格哈达斯·雅各布·弗里斯
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Hub Organ Intellectual Property Co ltd
Koninklijke Nederlandse Akademie van Wetenschappen
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Stijin Hublezhi Organic Technology Co ltd
Koninklijke Nederlandse Akademie van Wetenschappen
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CN201880089039.1A 2017-12-21 2018-12-21 免疫细胞类器官共培养物 Pending CN111989569A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1721615.1 2017-12-21
GBGB1721615.1A GB201721615D0 (en) 2017-12-21 2017-12-21 Immune cell organoid co-cultures
PCT/EP2018/086716 WO2019122388A1 (en) 2017-12-21 2018-12-21 Immune cell organoid co-cultures

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US (1) US12517112B2 (https=)
EP (1) EP3729084A1 (https=)
JP (2) JP7561028B2 (https=)
KR (1) KR20200105852A (https=)
CN (1) CN111989569A (https=)
AU (3) AU2018390960B2 (https=)
BR (1) BR112020012565A2 (https=)
CA (1) CA3086290A1 (https=)
GB (1) GB201721615D0 (https=)
IL (1) IL275354A (https=)
SG (1) SG11202005891TA (https=)
WO (1) WO2019122388A1 (https=)

Cited By (14)

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Publication number Priority date Publication date Assignee Title
CN109536444A (zh) * 2018-12-11 2019-03-29 吉林省拓华生物科技有限公司 一种适用于恶性实体瘤肿瘤浸润t淋巴细胞的分离诱导方法
CN111411084A (zh) * 2020-04-28 2020-07-14 江苏信安佳医疗科技有限公司 一种用于构建肝肿瘤无支架类器官的培养基及培养方法
CN112481193A (zh) * 2020-11-26 2021-03-12 海西纺织新材料工业技术晋江研究院 三维培养肠及肠癌组织类器官的标准化培养基及培养方法
CN112553289A (zh) * 2020-12-17 2021-03-26 深圳市第二人民医院(深圳市转化医学研究院) 一种评价car-t细胞有效性的方法
CN113881630A (zh) * 2021-09-28 2022-01-04 创芯国际生物科技(广州)有限公司 一种肿瘤特异性til细胞的培育分离方法
CN115386550A (zh) * 2022-10-26 2022-11-25 成都诺医德医学检验实验室有限公司 一种评价免疫细胞抗癌有效性的方法
CN115466716A (zh) * 2022-10-24 2022-12-13 徐州市中心医院 一种患者源性口腔黏液表皮样癌类器官的构建方法及应用
CN115521912A (zh) * 2021-11-04 2022-12-27 上海万何圆生物科技有限公司 一种以类器官与t细胞共培养的免疫细胞治疗方法及应用
CN115521898A (zh) * 2021-11-04 2022-12-27 上海万何圆生物科技有限公司 肝癌类器官与nk细胞共培养的免疫细胞治疗方法及应用
CN115537395A (zh) * 2021-11-04 2022-12-30 上海万何圆生物科技有限公司 一种肝癌类器官与TILs细胞共培养的治疗方法及其应用
CN116515938A (zh) * 2023-07-04 2023-08-01 天津市肿瘤医院空港医院 基于肿瘤类器官模型筛选个体化肿瘤新抗原疫苗的方法
CN118006555A (zh) * 2024-04-10 2024-05-10 北京市肿瘤防治研究所 一种黑色素瘤类器官培养基及其用途
CN118240750A (zh) * 2024-05-28 2024-06-25 淇嘉科技(苏州)有限公司 具有免疫细胞的结肠类器官构建方法
WO2025167821A1 (zh) * 2024-02-05 2025-08-14 苏州沙砾生物科技有限公司 一种免疫细胞的培养方法和应用

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US10006904B2 (en) 2011-12-19 2018-06-26 Umc Utrecht Holding B.V. Rapid quantitative assay to measure CFTR function in a primary intestinal culture model
CA2949171A1 (en) 2014-05-16 2015-11-19 Koninklijke Nederlandse Akademie Van Wetenschappen Improved culture method for organoids
GB201421092D0 (en) 2014-11-27 2015-01-14 Koninklijke Nederlandse Akademie Van Wetenschappen Culture medium
GB201603569D0 (en) 2016-03-01 2016-04-13 Koninklijke Nederlandse Akademie Van Wetenschappen Improved differentiation method
GB201721615D0 (en) 2017-12-21 2018-02-07 Koninklijke Nederlandse Akademie Van Wetenschappen Immune cell organoid co-cultures
US10395772B1 (en) * 2018-10-17 2019-08-27 Tempus Labs Mobile supplementation, extraction, and analysis of health records
GB201819224D0 (en) 2018-11-26 2019-01-09 Koninklijke Nederlandse Akademie Van Wetenschappen Hepatocyte expansion methods
EP3891755A4 (en) 2018-12-03 2022-09-07 Tempus Labs, Inc. IDENTIFICATION, EXTRACTION AND PREDICTION SYSTEM FOR CLINICAL CONCEPTS AND RELATED PROCEDURES
MX2021014439A (es) * 2019-05-28 2022-05-19 Xilis Inc Metodos y aparatos para microorganoesferas derivadas de pacientes.
WO2021067338A1 (en) * 2019-09-30 2021-04-08 Kloxin April Indirect three-dimensional co-culture of dormant tumor cells and uses thereof
CN114585746A (zh) * 2019-10-17 2022-06-03 公立大学法人横滨市立大学 药物毒性评价方法
WO2021092226A1 (en) * 2019-11-05 2021-05-14 Em-O-Em Diagnostics, Inc. Embryo transfer outcome prediction using endometrial organoids and spent embryo culture medium
WO2021097074A1 (en) * 2019-11-13 2021-05-20 New York University Intestinal organoid co-culture systems and methods for treating or preventing a disease or disorder associated with immune response-mediated tissue injury
CN111040997A (zh) * 2019-12-20 2020-04-21 北京科途医学科技有限公司 一种具有肿瘤免疫微环境的前列腺癌类器官培养及冻存方法
CN111089977A (zh) * 2019-12-30 2020-05-01 浙江科途医学科技有限公司 一种利用类器官检测溶瘤病毒有效性的方法
CN113249325B (zh) * 2020-02-11 2023-02-17 合肥中科普瑞昇生物医药科技有限公司 食管鳞癌原代细胞的培养基及培养方法
US20230212510A1 (en) * 2020-05-04 2023-07-06 City Of Hope Methods for organoids production
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