CN109254162A - 操作实验室样本分配系统的方法、实验室样本分配系统和实验室自动化系统 - Google Patents
操作实验室样本分配系统的方法、实验室样本分配系统和实验室自动化系统 Download PDFInfo
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Abstract
本发明涉及操作实验室样本分配系统的方法、实验室样本分配系统和实验室自动化系统。具体公开了如下内容:实验室样本分配系统(100)包括:若干样本容器载体(140);网关(150),其具有网络接口(151);以及若干运输模块(120_1到120_n)。所述方法包括以下步骤:将探查命令从所述网关(150)发送到所述第一运输模块(120_1);将初始化命令从所述第一运输模块(120_1)传送到剩余的运输模块(120_2到120_n);将地址存储在所述运输模块(120_1到120_n)内,其中,相应的运输模块(120_1到120_n)的存储地址对应于对应的运输模块(120_1到120_n)定位于其中的列(C0到C6)和行(R0到R8);以及由所述网关(150)使用所述地址来对所述运输模块(120_1到120_n)进行寻址。
Description
技术领域
本发明涉及一种操作实验室样本分配系统的方法、一种实验室样本分配系统和一种包括实验室样本分配系统的实验室自动化系统。
背景技术
WO 2013/064656 A1公开了一种包括若干样本容器载体的实验室样本分配系统。所述系统还包括若干运输模块,其中,每个运输模块包括运输表面。布置成彼此邻近的运输模块的运输表面形成共同运输表面。所述系统还包括可控型驱动装置,所述可控型驱动装置布置在相应的运输模块的运输表面下方并且适于在运输表面上移动样本容器载体。
发明内容
本发明的目标是提供一种操作实验室样本分配系统的方法、一种实验室样本分配系统和一种包括实验室样本分配系统的实验室自动化系统,以上各者具有高度可扩展性和模块化,特别地提供简单的寻址方案。
本发明借助于根据权利要求1的操作实验室样本分配系统的方法、借助于根据权利要求5的实验室样本分配系统和借助于根据权利要求6的实验室自动化系统来解决这个目标。
所述方法旨在操作实验室样本分配系统。
实验室样本分配系统包括若干(例如,2至2000个)样本容器载体,这些样本容器载体适于载送样本容器(通常为包括医学样本的样本管)。
实验室样本分配系统还包括网关(gateway),所述网关具有至少一个网络接口,例如呈以太网网络接口、通用现场(generic field)总线接口、RS 485网络接口等的形式。网关可例如被具体体现为个人计算机。网关可例如实现实验室样本分配系统的所有必要的更高层控制功能。
实验室样本分配系统还包括若干(例如,2至1000个)运输模块,其中,每个运输模块包括适于载送/支撑样本容器载体的运输表面(也可表示为运输平面)。
运输模块能够沿行方向和列方向布置成彼此邻近,使得运输模块的运输表面一起形成沿行方向和/或列方向具有尺寸的共同运输表面。
相应的运输模块包括可控型驱动装置(例如,呈电磁体或螺线管的形式),所述可控型驱动装置成行(行方向)且成列(列方向)地布置在相应的运输表面下方并且适于在相应的运输表面上/之上移动样本容器载体。
相应的运输模块包括左网络接口、右网络接口、上网络接口、以及下网络接口。相应的运输模块的左网络接口和右网络接口适于连接沿行方向布置成彼此邻近的运输模块。因此,相应的运输模块的上网络接口和下网络接口适于连接沿列方向布置成彼此邻近的运输模块。
相应的运输模块可包括控制装置,所述控制装置被配置成通过对驱动装置进行驱动来控制样本容器载体在运输表面的顶部上的移动,以使得样本容器载体在运输表面上沿对应的和个体的运输路径而移动。控制装置可与左网络接口、右网络接口、上网络接口、以及下网络接口成信号连接,并且可存储个体地址。可由网关使用所述个体地址以寻址对应的运输模块的控制装置并与其通信。
网关的网络接口连接到运输模块中的至少一者的至少一个接口,其中,这个运输模块被表示为第一运输模块。
网关和若干运输模块适于相互作用,使得得以实施如下文所描述的方法。
本发明还涉及:一种实验室自动化系统,其包括若干预分析站、分析站和/或后分析站;以及如上文所描述的实验室样本分配系统,其适于在这些站之间运输样本容器载体和/或样本容器。
这些站可布置成邻近于实验室样本分配系统。
预分析站可适于对样本、样本容器和/或样本容器载体执行任何种类的预处理。
分析站可适于使用样本或样本的一部分以及试剂以产生测量信号,所述测量信号指示分析物是否存在以及如果存在其处于何种浓度。
后分析站可适于对样本、样本容器和/或样本容器载体执行任何种类的后处理。
预分析站、分析站和/或后分析站可包括以下各者中的至少一者:去盖站、重盖站、等分(aliquot)站、离心分离站、归档站、移液站、分类站、管类型识别站、样本质量确定站、附加缓冲站、液面检测站、以及密封/解除密封站。
所述方法包括用于将个体地址指派给运输模块中的每一者的以下步骤。
最初,网关将探查命令传输到第一运输模块,即传输到使其网络接口中的一者(左、右、上或下)连接到网关的网络接口的运输模块。探查命令可以是具有特征化此命令类型的特定识别符的命令。
第一运输模块接收探查命令,并且响应于接收到探查命令将初始化命令传输到直接连接到第一运输模块的所有运输模块。初始化命令可以是具有特征化此命令类型的特定识别符的命令。探查命令和初始化命令可彼此不同,或可以是相同的。初始化命令然后被传送到剩余的运输模块,相继地从一运输模块到另一运输模块。
响应于接收到初始化命令,将地址存储在相应的运输模块内,其中,相应的运输模块的存储地址对应于对应的运输模块定位于其中的行和列。
网关使用这些存储地址来对运输模块进行单独寻址。
在实施例中,所述方法包括另外的步骤:一旦由第一运输模块接收到探查命令,在第一运输模块内将列计数器的值和行计数器的值设定成相应的初始值(例如,零)并且将列计数器和行计数器存储在第一运输模块内;将初始化命令连同列计数器的相应值和行计数器的相应值或将包括列计数器的相应值和行计数器的相应值的初始化命令从第一运输模块发送到直接连接到第一运输模块的所有另外的运输模块;一旦由另外的运输模块接收到初始化命令以及列计数器的相应值和行计数器的相应值,a)如果由另外的运输模块的左网络接口或右网络接口接收到初始化命令以及列计数器的值和行计数器的值,则递增或递减接收到的列计数器的值并且将列计数器的经递增或经递减的值存储在另外的运输模块内以及将行计数器的接收值存储在另外的运输模块内,以及b)如果由另外的运输模块的上网络接口或下网络接口接收初始化命令以及列计数器的值和行计数器的值,则递增或递减接收到的行计数器的值并且将行计数器的经递增或经递减的值存储在另外的运输模块内以及将列计数器的接收值存储在另外的运输模块内;针对所有另外的运输模块重复步骤a)和b),直到所有的运输模块存储它们对应的列计数器和行计数器的值,并且将相应的列计数器和行计数器的值用作地址。
如果由一另外的运输模块的左网络接口接收到相应值,则可将列计数器的值例如递增1,并且如果由一另外的运输模块的右网络接口接收到相应值,则可将列计数器的值例如递减1。因此,如果由一另外的运输模块的上网络接口接收到相应值,则可将行计数器的值例如递增1,并且如果由一另外的运输模块的下网络接口接收到相应值,则可将行计数器的值例如递减1。
在实施例中,不言而喻,在传输消息期间,只有在相应的运输模块不是消息的接收器或目的地的情况下,所述相应的运输模块才将接收到的消息转送到布置在同一行和/或同一列中的邻近的运输模块。消息可以例如是由网关传输的命令或对由运输模块传输的命令的响应。可取决于目标地址来传输消息,直到所述消息由具有所述目标地址的接收器接收。
在实施例中,网关的网络接口或网关的另外的网络接口另外地连接到另外的运输模块的接口,其中,探查命令另外地从网关被发送到所述另外的运输模块。
附图说明
将关于附图详细描述本发明,在附图中:
图1示出根据本发明的实施例的实验室自动化系统,
图2示出包括在图1中所描绘的实验室自动化系统中的运输模块,以及
图3示出具有借助于创造性方法指派的地址的运输模块的可能布置。
具体实施方式
图1示出实验室自动化系统10,其包括实验室样本分配系统100和两个实验室站20,两个实验室站20可被具体体现为预分析站、分析站和/或后分析站20。站20布置成邻近于实验室样本分配系统100。不言而喻,比图1中所描绘的两个站20更多的站可被包括在实验室自动化系统10中。
实验室样本分配系统100包括沿行方向x和沿列方向y定位成彼此邻近的六个运输模块120。这些运输模块120分别包括形成一共同运输表面110的运输表面121。
多个电可控型驱动装置或电磁致动器(呈电磁体122的形式)按行和列的方式定位在相应的运输表面121下方。驱动装置122被实施为螺线管(solenoid),所述螺线管具有实心铁磁芯和环绕该铁磁芯的线圈。
样本容器载体140定位在共同运输表面110上,并且可以借助于驱动装置122移动。虽然应理解的是,多个样本容器载体140可以定位在共同运输表面110上,但是由于简单性,图1中仅描绘了三个样本容器载体140。样本容器载体140保持样本容器145,待分析的样本可以包含在样本容器145中。
每个样本容器载体140包括定位在相应的样本容器载体140内部的磁致激活装置141,其呈永磁体的形式。磁致激活装置141或永磁体适于与由驱动装置122产生的电磁场相互作用,以用于在共同运输表面110之上移动样本容器载体140。
实验室样本分配系统100适于在实验室站20之间运输样本容器载体140和/或样本容器145。实验室站20定位成邻近于运输表面110,使得样本容器载体140可以用于将包含在样本容器145中的样本运输到相应的实验室站20。
运输模块120通常具有相同的尺寸,并且可例如包括驱动装置122的6X6的矩阵。
实验室样本分配系统100还包括与运输模块120信号通信的网关150,如下文将更详细地解释的那样。
图2更详细地示例性地示出了四个运输模块120。每个运输模块120包括左网络接口126、右网络接口127、上网络接口128、以及下网络接口129。左网络接口126和右网络接口127适于连接沿行方向x布置成彼此邻近的运输模块120。上网络接口128和下网络接口129适于连接沿列方向y布置成彼此邻近的运输模块120。
图3示出运输模块120_1到120_n的可能布置,所述运输模块具有由相应的列计数器CC和相应的行计数器RC组成的地址,其借助于如下文将描述的创造性方法来指派。
网关150包括网络接口151,其中,网关150的网络接口151连接到第一运输模块120_1的左接口126并且选择性地连接到最后的运输模块120_n的右网络接口127。
网络接口可例如是以太网接口、RS 485接口、或无线接口。
运输模块120实际上布置在具有列C0到C6和行R0到R8的矩阵内部。此矩阵中的相应的运输模块120_1到120_n的列Ci (i = 0, 1, 2, …)和行Rj (j = 0, 1, 2, …)被用作相应的运输模块120_1到120_n的个体地址Ci/Rj。
指派地址Ci/Rj的方法包括以下步骤。
首先,网关150探查未知的系统构型。出于这个目的,网关150将探查命令发送到第一运输模块120_1,由此起始地址Ci/Rj的指派。
当第一运输模块120_1接收到探查命令时,第一运输模块120_1将列计数器CC的值和行计数器RC的值设定成作为零(0)的相应初始值,并且存储列计数器CC = 0和行计数器RC = 0。因此,第一运输模块120_1现在具有地址CC/RC= 0/0。
在下一步骤中,第一运输模块120_1将广播(broadcast)发送到直接连接到第一运输模块120_1的运输模块120_2,所述广播呈包括列计数器CC = 0的相应值和行计数器RC =0的相应值的初始化命令的形式。
当运输模块120_2接收到初始化命令时,运输模块120_2将接收到的列计数器CC的值递增到值1,存储列计数器CC的递增值1并且存储行计数器RC的接收值0,因为这些相应值由另外的运输模块120_2的左网络接口126接收。因此,运输模块120_2现在具有地址CC/RC=1/0。
在下一步骤中,运输模块120_2将初始化命令发送到直接连接到另外的运输模块120_2的运输模块120_3,所述初始化命令包括列计数器CC = 1的相应值和行计数器RC = 0的相应值。因此,运输模块120_3现在将地址评估为CC/RC= 2/0,并且在另外的重复之后运输模块120_4将其地址评估为CC/RC= 3/0。
由于两个运输模块120_5和120_6直接连接到运输模块120_4,所以可将两个地址同时指派给运输模块120_5和120_6。
由于运输模块120_5在其左接口126上接收到初始化命令,所以运输模块120_5将接收到的列计数器CC的值递增到值4并且让行计数器RC的接收值不变。因此,运输模块120_5将其地址评估为CC/RC= 4/0。
由于运输模块120_6在其上接口128上接收到初始化命令,所以运输模块120_6将列计数器CC的接收值递增到值1并且让列计数器CC的接收值不变。因此,运输模块120_6将其地址评估为CC/RC= 3/1。
重复所描述的步骤,直到所有的运输模块120_1到120_n已存储它们对应的列计数器CC和行计数器RC的值。
相应的列计数器CC和行计数器RC的值被用作用于与相应的运输模块120_1到120_n通信的个体地址。
可替代地或另外地使用运输模块120_n来起始寻址(addressing)过程。
借助于本发明,可以实现自组织网络。通常,仅使用节点到节点连接,其中,每个节点或运输模块与其直接的邻居通信。每个运输模块将消息转送到所有运输模块或转送到经寻址的运输模块。广播可以行进到不同的方向中。中心总线是不必要的。
通向网络的若干接入点是有可能的。在所述情况下,运输模块应忽略已被接收的命令或消息。出于所述目的,消息可具有独特ID。
在地址指派之后,每个运输模块知道其坐标、同向网关和其邻居的最快上行链路途径(uplink way)。
当运输模块从网关得到命令时,其必须对网关作出响应。上行链路邻居转送所述响应,直到网关接收到所述响应为止。
每个运输模块可包括现场可编程门阵列(FPGA),FPGA实施接口126到129以及地址指派和消息传送的逻辑。
Claims (6)
1.一种操作实验室样本分配系统(100)的方法,所述实验室样本分配系统(100)包括:
-若干样本容器载体(140),
- 网关(150),其具有网络接口(151),以及
- 若干运输模块(120_1到120_n),其中,每个运输模块(120_1到120_n)包括:
- 运输表面(121),其中,所述运输模块(120_1到120_n)能够沿行方向(x)和列方向(y)布置成彼此邻近,使得所述运输模块(120_1到120_n)的运输表面(121)一起形成共同运输表面(110),
- 可控型驱动装置(122),其布置在所述运输表面(121)下方并且适于在所述运输表面(121)上移动样本容器载体(140),
- 左网络接口(126)、右网络接口(127)、上网络接口(128)、以及下网络接口(129),
- 其中,所述左网络接口(126)和所述右网络接口(127)适于连接沿所述行方向(x)布置成彼此邻近的运输模块(120_1到120_n),并且所述上网络接口(128)和所述下网络接口(129)适于连接沿所述列方向(y)布置成彼此邻近的运输模块(120_1到120_n),
- 其中,所述网关(150)的网络接口(151)连接到第一运输模块(120_1)的网络接口(126),
- 所述方法包括以下步骤:
- 将探查命令从所述网关(150)发送到所述第一运输模块(120_1),
- 将初始化命令从所述第一运输模块(120_1)传送到剩余的运输模块(120_2到120_n),
- 将地址存储在所述运输模块(120_1到120_n)内,其中,相应的运输模块(120_1到120_n)的存储地址对应于对应的运输模块(120_1到120_n)定位于其中的列(C0到C6)和行(R0到R8),以及
- 由所述网关(150)使用所述地址来对所述运输模块(120_1到120_n)进行寻址。
2.根据权利要求1所述的方法,其特征在于,所述方法包括另外的步骤:
- 一旦由所述第一运输模块(120_1)接收到所述探查命令,在所述第一运输模块(120_1)内将列计数器(CC)的值和行计数器(RC)的值设定成相应的初始值并且将所述列计数器(CC)和所述行计数器(RC)存储在所述第一运输模块(120_1)内,
- 将所述初始化命令连同所述列计数器(CC)的相应值和所述行计数器(RC)的相应值从第一运输模块(120_1)发送到直接连接到所述第一运输模块(120_1)的另外的运输模块(120_2),
- 一旦由所述另外的运输模块(120_2)接收到所述初始化命令,
a) 如果由所述另外的运输模块(120_2)的左网络接口(126)或右网络接口(127)接收到所述初始化命令,则递增或递减接收到的列计数器(CC)的值并存储所述列计数器(CC)的经递增或经递减的值以及将所述行计数器(RC)的接收值存储在所述另外的运输模块(120_2)内,以及
b)如果由所述另外的运输模块(120_2)的上网络接口(128)或下网络接口(129)接收到所述初始化命令,则递增或递减接收到的行计数器(RC)的值并存储所述行计数器(RC)的经递增或经递减的值以及将所述列计数器(CC)的接收值存储在所述另外的运输模块(120_2)内,
-针对所有另外的运输模块(120_3到120_n)重复步骤a)和b),直到所有的运输模块(120_1到120_n)已存储它们对应的列计数器(CC)和行计数器(RC)的值,并且
- 将相应的列计数器(CC)和行计数器(RC)的值用作地址。
3.根据权利要求1或2所述的方法,其特征在于
-在传输消息期间,相应的运输模块(120_1到120_n)将接收到的消息转送到布置在同一行和/或同一列中的邻近的运输模块(120_1到120_n)。
4.根据前述权利要求中的任一项所述的方法,其特征在于
- 所述网关(150)的网络接口(151)另外地连接到另外的运输模块(120_n)的接口(127),其中,所述探查命令另外地从所述网关(150)发送到所述另外的运输模块(120_n)。
5.一种实验室样本分配系统(100),所述实验室样本分配系统(100)包括:
-若干样本容器载体(140),
- 网关(150),其具有网络接口(151),以及
- 若干运输模块(120_1到120_n),其中,每个运输模块(120_1到120_n)包括:
- 运输表面(121),其中,所述运输模块(120_1到120_n)能够沿行方向(x)和列方向(y)布置成彼此邻近,使得所述运输模块(120_1到120_n)的运输表面(121)一起形成共同运输表面(110),
- 可控型驱动装置(122),其布置在所述运输表面(121)下方并且适于在所述运输表面(121)上移动样本容器载体(140),
- 左网络接口(126)、右网络接口(127)、上网络接口(128)、以及下网络接口(129),
- 其中,所述左网络接口(126)和所述右网络接口(127)适于连接沿所述行方向(x)布置成彼此邻近的运输模块(120_1到120_n),并且所述上网络接口(128)和所述下网络接口(129)适于连接沿所述列方向(y)布置成彼此邻近的运输模块(120_1到120_n),
- 其中,所述网关(150)的网络接口(151)连接到第一运输模块(120_1)的接口(126),
- 其中,所述网关(150)和所述若干运输模块(120_1到120_n)适于相互作用,使得得以实施前述权利要求中的任一项所述的方法。
6.一种实验室自动化系统(10),包括:
- 若干预分析站、分析站和/或后分析站(20),以及
- 根据权利要求5所述的实验室样本分配系统(100),其适于在所述站(20)之间运输所述样本容器载体(140)和/或样本容器(145)。
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US10962557B2 (en) | 2021-03-30 |
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