CN102711768B - 用于预防和治疗心衰的组合物和方法 - Google Patents
用于预防和治疗心衰的组合物和方法 Download PDFInfo
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- CN102711768B CN102711768B CN201080026141.0A CN201080026141A CN102711768B CN 102711768 B CN102711768 B CN 102711768B CN 201080026141 A CN201080026141 A CN 201080026141A CN 102711768 B CN102711768 B CN 102711768B
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- Veterinary Medicine (AREA)
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- Pharmacology & Pharmacy (AREA)
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- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
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- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Neurology (AREA)
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US18670909P | 2009-06-12 | 2009-06-12 | |
| US61/186,709 | 2009-06-12 | ||
| US18790509P | 2009-06-17 | 2009-06-17 | |
| US61/187,905 | 2009-06-17 | ||
| PCT/IB2010/001410 WO2010143058A1 (en) | 2009-06-12 | 2010-06-11 | Compositions and methods for the prevention and treatment of heart failure |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102711768A CN102711768A (zh) | 2012-10-03 |
| CN102711768B true CN102711768B (zh) | 2014-04-09 |
Family
ID=43308481
Family Applications (6)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201080026141.0A Expired - Fee Related CN102711768B (zh) | 2009-06-12 | 2010-06-11 | 用于预防和治疗心衰的组合物和方法 |
| CN201080026127.0A Expired - Fee Related CN102497873B (zh) | 2009-06-12 | 2010-06-11 | 用于增加生存年限和健康年限的组合物和方法 |
| CN201080026126.6A Expired - Fee Related CN102740870B (zh) | 2009-06-12 | 2010-06-11 | 日本路边青有机提取物在制备用于治疗或预防高血压药物中的用途 |
| CN201080030503.3A Expired - Fee Related CN102548560B (zh) | 2009-06-12 | 2010-06-11 | 用于预防和治疗冠心病的组合物和方法 |
| CN201080026128.5A Expired - Fee Related CN102573865B (zh) | 2009-06-12 | 2010-06-11 | 用于预防和治疗红细胞聚集的组合物 |
| CN201080030502.9A Expired - Fee Related CN102548571B (zh) | 2009-06-12 | 2010-06-11 | 用于预防和治疗脑部疾病和疾病状态的组合物和方法 |
Family Applications After (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201080026127.0A Expired - Fee Related CN102497873B (zh) | 2009-06-12 | 2010-06-11 | 用于增加生存年限和健康年限的组合物和方法 |
| CN201080026126.6A Expired - Fee Related CN102740870B (zh) | 2009-06-12 | 2010-06-11 | 日本路边青有机提取物在制备用于治疗或预防高血压药物中的用途 |
| CN201080030503.3A Expired - Fee Related CN102548560B (zh) | 2009-06-12 | 2010-06-11 | 用于预防和治疗冠心病的组合物和方法 |
| CN201080026128.5A Expired - Fee Related CN102573865B (zh) | 2009-06-12 | 2010-06-11 | 用于预防和治疗红细胞聚集的组合物 |
| CN201080030502.9A Expired - Fee Related CN102548571B (zh) | 2009-06-12 | 2010-06-11 | 用于预防和治疗脑部疾病和疾病状态的组合物和方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (7) | US9050277B2 (enExample) |
| EP (6) | EP2440221A4 (enExample) |
| JP (11) | JP6076737B2 (enExample) |
| CN (6) | CN102711768B (enExample) |
| AU (11) | AU2010258355B2 (enExample) |
| WO (6) | WO2010143062A1 (enExample) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12397008B2 (en) * | 2006-04-13 | 2025-08-26 | Lead Billion Limited | Pharmaceutical composition and method for regenerating myofibers in the treatment of muscle injuries |
| WO2010143062A1 (en) * | 2009-06-12 | 2010-12-16 | Generex Pharmaceuticals, Inc. | Compositions and methods for prevention and treatment of coronary heart diseases |
| KR20140010936A (ko) * | 2010-12-23 | 2014-01-27 | 후야 바이오사이언스 인터내셔널 엘엘씨 | 정제된 카디오게닌 이성질체 및 관련된 방법 |
| JP6000521B2 (ja) * | 2011-08-10 | 2016-09-28 | 株式会社ブルボン | 血圧上昇抑制剤 |
| EP2812005B8 (en) * | 2012-05-16 | 2018-10-31 | Prairie Berry Europe GmbH | Polyhydroxylated pentacyclic triterpene acids as hmg-coa reductase inhibitors |
| US20140044813A1 (en) * | 2012-08-09 | 2014-02-13 | Kemin Industries, Inc. | Plant Extracts for Improving Cognitive Health and Function |
| CN103623753B (zh) * | 2013-11-27 | 2016-03-23 | 大兴安岭嘉迪欧营养原料有限公司 | 大兴安岭野生金老梅总三萜提取物的制备方法 |
| CN103623082B (zh) * | 2013-11-29 | 2016-08-17 | 江西中医药大学 | 覆盆子提取物及其应用 |
| US20150174057A1 (en) * | 2013-12-24 | 2015-06-25 | Generex Pharamaceutics Inc. | Compositions and methods for the prevention and treatment of oral diseases |
| KR20160113277A (ko) * | 2014-01-30 | 2016-09-28 | 케민 인더스트리즈, 인코포레이티드 | 인지 기능을 개선시키기 위한 식물 추출물 |
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| CA2997659C (en) * | 2015-09-04 | 2023-08-01 | Reto ASMIS | Methods for treatment of monocyte dysfunction and chronic inflammatory micro- and macro-vascular diseases |
| CN105106222B (zh) * | 2015-09-14 | 2020-05-08 | 新乡医学院 | 吐曼酸在制备治疗或预防雌激素缺乏引起的阿尔茨海默病药物中的应用 |
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| JP7361470B2 (ja) | 2016-06-20 | 2023-10-16 | バタフライ ネットワーク,インコーポレイテッド | ユーザによる超音波装置の操作を援助するための自動画像取得 |
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| CN114722066B (zh) * | 2022-03-23 | 2023-04-07 | 电子科技大学 | 一种预测材料自旋霍尔电导及反常霍尔电导的方法 |
| CN117257781A (zh) * | 2022-06-13 | 2023-12-22 | 上海市东方医院(同济大学附属东方医院) | 美金刚通过靶向心房心肌细胞谷氨酸受体有效干预房颤 |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1558769A (zh) * | 2001-11-21 | 2004-12-29 | ���Ĵ���ѧ | 包括大根草有机提取物的组合物及其应用 |
| CN1708313A (zh) * | 2002-12-10 | 2005-12-14 | 香港中文大学 | 柔毛水杨梅的有机提取物及其应用 |
| CN101406537A (zh) * | 2007-10-11 | 2009-04-15 | 首都医科大学 | 柔毛水杨梅提取物用于制备治疗肥胖的药物的用途 |
Family Cites Families (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4522811A (en) | 1982-07-08 | 1985-06-11 | Syntex (U.S.A.) Inc. | Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides |
| JP2871763B2 (ja) * | 1989-12-15 | 1999-03-17 | 株式会社資生堂 | テストステロン―5α―レダクターゼ阻害剤 |
| CN1069629A (zh) | 1991-08-27 | 1993-03-10 | 段民生 | 一种康复面的制备方法 |
| CN1047089C (zh) * | 1992-12-03 | 1999-12-08 | 张斌 | 治疗近视眼的药物及制备工艺 |
| CN1102993A (zh) | 1993-12-21 | 1995-05-31 | 吴文才 | 多酶体系加工中草药的制剂方法 |
| JPH07179347A (ja) * | 1993-12-21 | 1995-07-18 | Showa Shell Sekiyu Kk | 抗ウイルス組成物 |
| US5589154A (en) | 1994-11-22 | 1996-12-31 | Rutgers, The State University Of New Jersey | Methods for the prevention or treatment of vascular hemorrhaging and Alzheimer's disease |
| CA2289531C (en) | 1997-05-15 | 2009-09-29 | University Of Washington | Composition and methods for treating alzheimer's disease and other amyloidoses |
| CN1176814A (zh) | 1997-06-26 | 1998-03-25 | 李静 | 预防和治疗脑血管病的口服液 |
| CN1102399C (zh) | 2000-06-09 | 2003-03-05 | 张庆玉 | 降脂通脉胶囊 |
| AU2001278341A1 (en) * | 2000-07-26 | 2002-02-05 | Vitaplant Ag | Piper methysticum plant extract |
| WO2002009720A1 (en) * | 2000-07-31 | 2002-02-07 | University Of Virginia Patent Foundation | Inhibitors of dna polymerase sigma |
| US6629835B2 (en) | 2000-08-01 | 2003-10-07 | Metaproteomics, Llc | Combinations of diterpene triepoxide lactones and ditepene lactones or triterpenes for synergistic inhibition of cyclooxygenase-2 |
| JP2002255804A (ja) * | 2001-03-02 | 2002-09-11 | Suntory Ltd | インシュリン様作用を有するヘキサオキシジフェン酸誘導体を含んでなる組成物 |
| WO2002078685A1 (en) | 2001-03-30 | 2002-10-10 | The Nisshin_Oillio, Ltd. | Drugs for vascular lesion |
| KR100453569B1 (ko) * | 2001-09-11 | 2004-10-20 | 대한민국 | 3,4,5-트리히드록시벤즈알데히드를 유효성분으로 포함하는항산화제 |
| JP2003201229A (ja) | 2001-10-23 | 2003-07-18 | Shiseido Co Ltd | マトリックスメタロプロテアーゼ活性阻害剤および抗老化用化粧料 |
| JP4393777B2 (ja) | 2002-03-19 | 2010-01-06 | 株式会社ファンケル | 抗ヘリコバクター・ピロリ用組成物 |
| CN1239155C (zh) * | 2003-01-23 | 2006-02-01 | 北京中医药大学 | 一种治疗缺血性脑中风的药物组合物及其制备方法 |
| US20040247698A1 (en) * | 2003-06-04 | 2004-12-09 | Valenzuela Cortes Carmen Maria | Erectile Dysfunction Treatment |
| US20070249711A1 (en) * | 2003-10-10 | 2007-10-25 | Wonrack Choi | Triterpene Compounds which are Effective on Improvement of Brain Function |
| CN1185007C (zh) | 2003-12-08 | 2005-01-19 | 张小朋 | 降脂溶栓药物 |
| CN100509008C (zh) * | 2004-04-12 | 2009-07-08 | 赵晓昂 | 舒痛方及其制剂和用途 |
| WO2006054370A1 (en) * | 2004-11-16 | 2006-05-26 | Use-Techno Corporation | Gluconeogenesis inhibiting agent |
| KR100704003B1 (ko) * | 2005-06-10 | 2007-04-06 | 안동대학교 산학협력단 | 2-알파-하이드록시-올레아놀산을 함유하는 트롬빈 저해혈전증 예방 및 치료용 조성물 |
| JP2006347967A (ja) * | 2005-06-16 | 2006-12-28 | Yuusu Techno Corporation:Kk | 血糖値上昇抑制剤 |
| WO2007049089A1 (en) * | 2005-10-27 | 2007-05-03 | Lead Billion Limited | Method of stimulating growth of functional blood vessels and/or regeneration of myocardium in damaged tissues |
| WO2007049088A1 (en) | 2005-10-27 | 2007-05-03 | Lead Billion Limited | Method of stimulating growth of functional blood vessels and/or regeneration of myocardium in damaged tissues |
| AU2006308338B2 (en) | 2005-10-27 | 2009-11-05 | Lead Billion Limited | Pharmaceutical composition and method for neoangiogenesis/revascularization useful in treating ischemic heart diseases |
| KR100718602B1 (ko) * | 2005-12-29 | 2007-06-21 | 대한민국 | 항비만 및 항염증 효과를 가지는 뱀무 추출물, 이를포함하는 식품 조성물 및 이들의 제조 방법 |
| JP2007204447A (ja) * | 2006-02-03 | 2007-08-16 | Yoshihiro Futamura | 中性脂肪減少作用を呈するカルニチン誘導体、それからなる抗肥満薬、食品製剤及びセルライト減少作用を呈する化粧品 |
| JP4731350B2 (ja) | 2006-02-17 | 2011-07-20 | 丸善製薬株式会社 | 抗老化剤、皮膚化粧料及び美容用飲食品 |
| CA2646240A1 (en) * | 2006-03-16 | 2007-09-20 | Xuemin Shi | Combination therapy for treatment of patients with neurological disorders and cerebral infarction |
| CN1857627B (zh) * | 2006-04-12 | 2010-05-19 | 贵阳利多药物技术开发有限公司 | 治疗中风的中药制剂及其制备方法 |
| US8821947B2 (en) | 2006-06-01 | 2014-09-02 | Howard W. Selby, III | Cholesterol-reducing diet |
| CN101091751A (zh) * | 2006-06-22 | 2007-12-26 | 北京中医药大学 | 一种治疗高血压的中药组合物及其制备方法 |
| JP5281234B2 (ja) * | 2006-06-27 | 2013-09-04 | ポーラ化成工業株式会社 | 毛様体過緊張による疲れ目の改善・予防のための経口投与組成物 |
| CN100528195C (zh) * | 2006-06-28 | 2009-08-19 | 海南晨菲药业有限公司 | 一种大青根注射剂制备工艺 |
| CN101099770A (zh) | 2006-07-04 | 2008-01-09 | 北京中医药大学 | 一种具有咪唑啉受体激动活性的药物组合物及制备方法和应用 |
| JP2008074801A (ja) | 2006-09-25 | 2008-04-03 | Oriza Yuka Kk | 肝保護剤 |
| JP5366358B2 (ja) * | 2006-09-29 | 2013-12-11 | 株式会社コーセー | 皮膚の老化機構に作用する剤、抗老化用皮膚外用剤、及び抗老化方法 |
| CN101040901A (zh) | 2007-04-12 | 2007-09-26 | 云南龙润药业有限公司 | 迷迭香提取物及其制备方法和应用 |
| US9205112B2 (en) | 2007-04-23 | 2015-12-08 | Creative Medical Health, Inc. | Combination treatment of cardiovascular disease |
| US20100189830A1 (en) | 2007-05-21 | 2010-07-29 | Zhijun Liu | Sweet Gum Fruit Extract as a Therapeutic Agent |
| US20090022827A1 (en) * | 2007-07-19 | 2009-01-22 | Ming Li | Agent and method for eliminating malignance of cancer cells without harmful effect to normal cells |
| CN101125171B (zh) | 2007-08-20 | 2010-05-26 | 刘凤元 | 一种男、女补强中药 |
| KR100891881B1 (ko) | 2007-08-23 | 2009-04-07 | 대한민국 | 3,4,5-트리히드록시벤즈알데히드를 유효성분으로 포함하는고지혈증 및 mmp 과다활성으로 인한 혈관질환 예방 및치료용 조성물 |
| CN101274012B (zh) | 2008-01-23 | 2011-12-28 | 上海海天医药科技开发有限公司 | 夏枯草属植物提取物的组合物、制备方法及其药物用途 |
| WO2010143062A1 (en) | 2009-06-12 | 2010-12-16 | Generex Pharmaceuticals, Inc. | Compositions and methods for prevention and treatment of coronary heart diseases |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1558769A (zh) * | 2001-11-21 | 2004-12-29 | ���Ĵ���ѧ | 包括大根草有机提取物的组合物及其应用 |
| CN1708313A (zh) * | 2002-12-10 | 2005-12-14 | 香港中文大学 | 柔毛水杨梅的有机提取物及其应用 |
| CN101406537A (zh) * | 2007-10-11 | 2009-04-15 | 首都医科大学 | 柔毛水杨梅提取物用于制备治疗肥胖的药物的用途 |
Non-Patent Citations (2)
| Title |
|---|
| 李建宽.柔毛水杨梅(Geum Japonicum Thunb. Vax. Chinese F. Bolle)诱导血管形成和心肌再生功能的活性物质研究.《中国优秀博硕士学位论文全文数据库(硕士) 医药卫生科技辑》.2007,(第01期),第E057-84页. * |
| 柔毛水杨梅(Geum Japonicum Thunb. Vax. Chinese F. Bolle)诱导血管形成和心肌再生功能的活性物质研究;李建宽;《中国优秀博硕士学位论文全文数据库(硕士) 医药卫生科技辑》;20070115(第01期);第14-18页,第46-47页 * |
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