CA2525994C - Silk biomaterials and methods of use thereof - Google Patents
Silk biomaterials and methods of use thereof Download PDFInfo
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- CA2525994C CA2525994C CA2525994A CA2525994A CA2525994C CA 2525994 C CA2525994 C CA 2525994C CA 2525994 A CA2525994 A CA 2525994A CA 2525994 A CA2525994 A CA 2525994A CA 2525994 C CA2525994 C CA 2525994C
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- silk
- fiber
- peo
- cells
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Classifications
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- D01D5/00—Formation of filaments, threads, or the like
- D01D5/0007—Electro-spinning
- D01D5/0015—Electro-spinning characterised by the initial state of the material
- D01D5/003—Electro-spinning characterised by the initial state of the material the material being a polymer solution or dispersion
- D01D5/0038—Electro-spinning characterised by the initial state of the material the material being a polymer solution or dispersion the fibre formed by solvent evaporation, i.e. dry electro-spinning
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
- A61L27/227—Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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- D—TEXTILES; PAPER
- D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
- D01F—CHEMICAL FEATURES IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS; APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OF CARBON FILAMENTS
- D01F1/00—General methods for the manufacture of artificial filaments or the like
- D01F1/02—Addition of substances to the spinning solution or to the melt
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- D—TEXTILES; PAPER
- D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
- D01F—CHEMICAL FEATURES IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS; APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OF CARBON FILAMENTS
- D01F4/00—Monocomponent artificial filaments or the like of proteins; Manufacture thereof
- D01F4/02—Monocomponent artificial filaments or the like of proteins; Manufacture thereof from fibroin
-
- D—TEXTILES; PAPER
- D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
- D01F—CHEMICAL FEATURES IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS; APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OF CARBON FILAMENTS
- D01F6/00—Monocomponent artificial filaments or the like of synthetic polymers; Manufacture thereof
- D01F6/88—Monocomponent artificial filaments or the like of synthetic polymers; Manufacture thereof from mixtures of polycondensation products as major constituent with other polymers or low-molecular-weight compounds
- D01F6/94—Monocomponent artificial filaments or the like of synthetic polymers; Manufacture thereof from mixtures of polycondensation products as major constituent with other polymers or low-molecular-weight compounds of other polycondensation products
-
- D—TEXTILES; PAPER
- D06—TREATMENT OF TEXTILES OR THE LIKE; LAUNDERING; FLEXIBLE MATERIALS NOT OTHERWISE PROVIDED FOR
- D06M—TREATMENT, NOT PROVIDED FOR ELSEWHERE IN CLASS D06, OF FIBRES, THREADS, YARNS, FABRICS, FEATHERS OR FIBROUS GOODS MADE FROM SUCH MATERIALS
- D06M13/00—Treating fibres, threads, yarns, fabrics or fibrous goods made from such materials, with non-macromolecular organic compounds; Such treatment combined with mechanical treatment
- D06M13/10—Treating fibres, threads, yarns, fabrics or fibrous goods made from such materials, with non-macromolecular organic compounds; Such treatment combined with mechanical treatment with compounds containing oxygen
- D06M13/165—Ethers
- D06M13/17—Polyoxyalkyleneglycol ethers
-
- D—TEXTILES; PAPER
- D06—TREATMENT OF TEXTILES OR THE LIKE; LAUNDERING; FLEXIBLE MATERIALS NOT OTHERWISE PROVIDED FOR
- D06M—TREATMENT, NOT PROVIDED FOR ELSEWHERE IN CLASS D06, OF FIBRES, THREADS, YARNS, FABRICS, FEATHERS OR FIBROUS GOODS MADE FROM SUCH MATERIALS
- D06M15/00—Treating fibres, threads, yarns, fabrics, or fibrous goods made from such materials, with macromolecular compounds; Such treatment combined with mechanical treatment
- D06M15/01—Treating fibres, threads, yarns, fabrics, or fibrous goods made from such materials, with macromolecular compounds; Such treatment combined with mechanical treatment with natural macromolecular compounds or derivatives thereof
- D06M15/03—Polysaccharides or derivatives thereof
-
- D—TEXTILES; PAPER
- D06—TREATMENT OF TEXTILES OR THE LIKE; LAUNDERING; FLEXIBLE MATERIALS NOT OTHERWISE PROVIDED FOR
- D06M—TREATMENT, NOT PROVIDED FOR ELSEWHERE IN CLASS D06, OF FIBRES, THREADS, YARNS, FABRICS, FEATHERS OR FIBROUS GOODS MADE FROM SUCH MATERIALS
- D06M15/00—Treating fibres, threads, yarns, fabrics, or fibrous goods made from such materials, with macromolecular compounds; Such treatment combined with mechanical treatment
- D06M15/01—Treating fibres, threads, yarns, fabrics, or fibrous goods made from such materials, with macromolecular compounds; Such treatment combined with mechanical treatment with natural macromolecular compounds or derivatives thereof
- D06M15/03—Polysaccharides or derivatives thereof
- D06M15/11—Starch or derivatives thereof
Landscapes
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Textile Engineering (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Dermatology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Transplantation (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Dispersion Chemistry (AREA)
- Mechanical Engineering (AREA)
- Manufacturing & Machinery (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Zoology (AREA)
- Botany (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Materials For Medical Uses (AREA)
- Nonwoven Fabrics (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Manufacture Of Porous Articles, And Recovery And Treatment Of Waste Products (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US39092902P | 2002-06-24 | 2002-06-24 | |
| US60/390,929 | 2002-06-24 | ||
| US40273802P | 2002-08-12 | 2002-08-12 | |
| US60/402,738 | 2002-08-12 | ||
| US43029102P | 2002-12-02 | 2002-12-02 | |
| US60/430,291 | 2002-12-02 | ||
| PCT/US2003/019968 WO2004000915A2 (en) | 2002-06-24 | 2003-06-24 | Silk biomaterials and methods of use thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2525994A1 CA2525994A1 (en) | 2003-12-31 |
| CA2525994C true CA2525994C (en) | 2012-10-16 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2525994A Expired - Lifetime CA2525994C (en) | 2002-06-24 | 2003-06-24 | Silk biomaterials and methods of use thereof |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US7674882B2 (https=) |
| EP (4) | EP2447055B1 (https=) |
| JP (3) | JP4638735B2 (https=) |
| AU (1) | AU2003249366A1 (https=) |
| CA (1) | CA2525994C (https=) |
| WO (1) | WO2004000915A2 (https=) |
Families Citing this family (265)
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| WO2002000142A2 (en) * | 2000-06-29 | 2002-01-03 | Mount Sinai Hospital | Intervertebral disc |
| US20110009960A1 (en) * | 2001-11-16 | 2011-01-13 | Allergan, Inc. | Prosthetic fabric structure |
| US6902932B2 (en) | 2001-11-16 | 2005-06-07 | Tissue Regeneration, Inc. | Helically organized silk fibroin fiber bundles for matrices in tissue engineering |
| AU2003249366A1 (en) * | 2002-06-24 | 2004-01-06 | Tufts University | Silk biomaterials and methods of use thereof |
| WO2004062697A2 (en) | 2003-01-07 | 2004-07-29 | Tufts University | Silk fibroin materials and use thereof |
| EP1613796B1 (en) | 2003-04-10 | 2017-03-22 | Tufts University | Concentrated aqueous silk fibroin solution and use thereof |
| US8383158B2 (en) | 2003-04-15 | 2013-02-26 | Abbott Cardiovascular Systems Inc. | Methods and compositions to treat myocardial conditions |
| WO2005000483A1 (en) | 2003-06-06 | 2005-01-06 | Tufts University | Method for forming inorganic coatings |
| CA2558585C (en) | 2004-02-27 | 2010-10-12 | Amgen Inc. | Compounds, pharmaceutical compositions and methods for use in treating metabolic disorders |
| GB0405045D0 (en) | 2004-03-05 | 2004-04-07 | Spinox Ltd | Composite materials |
| JP4526851B2 (ja) * | 2004-03-31 | 2010-08-18 | 明彦 谷岡 | 多糖類のナノスケールの繊維および成形体 |
| KR101260981B1 (ko) | 2004-06-04 | 2013-05-10 | 더 보오드 오브 트러스티스 오브 더 유니버시티 오브 일리노이즈 | 인쇄가능한 반도체소자들의 제조 및 조립방법과 장치 |
| CA2608862C (en) | 2004-06-11 | 2020-05-05 | Trustees Of Tufts College | Silk-based drug delivery system |
| GB2417904A (en) * | 2004-09-14 | 2006-03-15 | Spinox Ltd | Tubular prosthesis for nerve regeneration |
| US8106014B2 (en) * | 2004-09-14 | 2012-01-31 | Neurotex Limited | Methods and apparatus for enhanced growth of peripheral nerves and nervous tissue |
| US20060204539A1 (en) | 2005-03-11 | 2006-09-14 | Anthony Atala | Electrospun cell matrices |
| AU2006223112B2 (en) | 2005-03-11 | 2011-12-01 | Wake Forest University Health Sciences | Production of tissue engineered heart valves |
| AU2006223063B2 (en) | 2005-03-11 | 2011-11-17 | Wake Forest University Health Sciences | Tissue engineered blood vessels |
| WO2006099332A2 (en) | 2005-03-11 | 2006-09-21 | Wake Forest University Health Sciences | Production of tissue engineered digits and limbs |
| CN100577720C (zh) * | 2005-03-21 | 2010-01-06 | 中国科学院化学研究所 | 可生物降解及吸收的聚合物纳米纤维膜材料及制法和用途 |
| US9539410B2 (en) | 2005-04-19 | 2017-01-10 | Abbott Cardiovascular Systems Inc. | Methods and compositions for treating post-cardial infarction damage |
| US20080125745A1 (en) | 2005-04-19 | 2008-05-29 | Shubhayu Basu | Methods and compositions for treating post-cardial infarction damage |
| ATE526378T1 (de) | 2005-08-02 | 2011-10-15 | Tufts College | Verfahren zur stufenweisen ablagerung von seidenfibroinbeschichtungen |
| DE102005042455A1 (de) * | 2005-09-06 | 2007-04-12 | Medizinische Hochschule Hannover | Nervenimplantat |
| CN100382772C (zh) * | 2005-09-28 | 2008-04-23 | 南通大学 | 含蚕丝丝素的医用神经移植物的制备方法 |
| JP5424561B2 (ja) * | 2005-12-02 | 2014-02-26 | サンスター スイス エスエー | エレクトロスピニング法により形成された生体適合性のナノ又はマイクロファイバー不織布を有する生体適合材、及びその製造方法 |
| US20080038236A1 (en) * | 2006-03-06 | 2008-02-14 | Artecel Sciences, Inc. | Biocompatible scaffolds and adipose-derived stem cells |
| EP1852470A1 (en) * | 2006-05-03 | 2007-11-07 | Technische Universität München | Multilayer Silk Protein Films |
| CN100404081C (zh) * | 2006-06-09 | 2008-07-23 | 浙江大学 | 一种网状组织工程支架 |
| US9242005B1 (en) | 2006-08-21 | 2016-01-26 | Abbott Cardiovascular Systems Inc. | Pro-healing agent formulation compositions, methods and treatments |
| CN100364621C (zh) * | 2006-08-30 | 2008-01-30 | 黄福华 | 人造血管丝素蛋白预凝涂层 |
| CN100364619C (zh) * | 2006-08-30 | 2008-01-30 | 郑军 | 人造血管丝素、胶原蛋白共混预凝涂层 |
| WO2008036051A1 (en) * | 2006-09-18 | 2008-03-27 | National University Of Singapore | Fiber structures and process for their preparation |
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-
2003
- 2003-06-24 AU AU2003249366A patent/AU2003249366A1/en not_active Abandoned
- 2003-06-24 EP EP12152178.5A patent/EP2447055B1/en not_active Expired - Lifetime
- 2003-06-24 EP EP17205284.7A patent/EP3351376B1/en not_active Expired - Lifetime
- 2003-06-24 WO PCT/US2003/019968 patent/WO2004000915A2/en not_active Ceased
- 2003-06-24 CA CA2525994A patent/CA2525994C/en not_active Expired - Lifetime
- 2003-06-24 JP JP2004530973A patent/JP4638735B2/ja not_active Expired - Lifetime
- 2003-06-24 EP EP03761306.4A patent/EP1558444B1/en not_active Expired - Lifetime
- 2003-06-24 EP EP20130166547 patent/EP2662211A1/en not_active Withdrawn
-
2004
- 2004-12-23 US US11/020,650 patent/US7674882B2/en not_active Expired - Lifetime
-
2010
- 2010-01-15 US US12/688,014 patent/US8071722B2/en not_active Expired - Lifetime
- 2010-08-19 JP JP2010183530A patent/JP2011019923A/ja not_active Withdrawn
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2014
- 2014-03-06 JP JP2014043805A patent/JP5855151B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| WO2004000915A2 (en) | 2003-12-31 |
| EP1558444A4 (en) | 2010-10-13 |
| EP1558444B1 (en) | 2016-09-21 |
| US8071722B2 (en) | 2011-12-06 |
| EP2662211A1 (en) | 2013-11-13 |
| EP2447055A1 (en) | 2012-05-02 |
| JP2014138877A (ja) | 2014-07-31 |
| EP3351376A1 (en) | 2018-07-25 |
| US20050260706A1 (en) | 2005-11-24 |
| EP1558444A2 (en) | 2005-08-03 |
| JP4638735B2 (ja) | 2011-02-23 |
| JP2006504450A (ja) | 2006-02-09 |
| EP3351376B1 (en) | 2023-04-12 |
| JP2011019923A (ja) | 2011-02-03 |
| JP5855151B2 (ja) | 2016-02-09 |
| CA2525994A1 (en) | 2003-12-31 |
| US20100196447A1 (en) | 2010-08-05 |
| AU2003249366A8 (en) | 2004-01-06 |
| WO2004000915A3 (en) | 2004-12-09 |
| EP2447055B1 (en) | 2017-12-06 |
| US7674882B2 (en) | 2010-03-09 |
| AU2003249366A1 (en) | 2004-01-06 |
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