IL123398A0 - Cloning methods for high strength spider silk proteins - Google Patents

Cloning methods for high strength spider silk proteins

Info

Publication number
IL123398A0
IL123398A0 IL12339896A IL12339896A IL123398A0 IL 123398 A0 IL123398 A0 IL 123398A0 IL 12339896 A IL12339896 A IL 12339896A IL 12339896 A IL12339896 A IL 12339896A IL 123398 A0 IL123398 A0 IL 123398A0
Authority
IL
Israel
Prior art keywords
high strength
spider silk
cloning methods
silk proteins
proteins
Prior art date
Application number
IL12339896A
Inventor
Richard M Basel
Glenn R Elion
Original Assignee
Agricola Tech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agricola Tech Inc filed Critical Agricola Tech Inc
Publication of IL123398A0 publication Critical patent/IL123398A0/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43513—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae
    • C07K14/43518—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae from spiders
IL12339896A 1995-08-22 1996-08-22 Cloning methods for high strength spider silk proteins IL123398A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US51769495A 1995-08-22 1995-08-22
PCT/US1996/013767 WO1997008315A1 (en) 1995-08-22 1996-08-22 Cloning methods for high strength spider silk proteins

Publications (1)

Publication Number Publication Date
IL123398A0 true IL123398A0 (en) 1998-09-24

Family

ID=24060849

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12339896A IL123398A0 (en) 1995-08-22 1996-08-22 Cloning methods for high strength spider silk proteins

Country Status (7)

Country Link
EP (1) EP0848754A1 (en)
JP (1) JPH11511325A (en)
CN (1) CN1200145A (en)
AU (1) AU7152996A (en)
BR (1) BR9612625A (en)
IL (1) IL123398A0 (en)
WO (1) WO1997008315A1 (en)

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FR2774588B1 (en) 1998-02-11 2000-05-05 Oreal COSMETIC OR DERMATOLOGICAL COMPOSITION CONTAINING AT LEAST ONE NATURAL, RECOMBINANT ARACHNID SILK PROTEIN OR THE LIKE
US7157615B2 (en) 1998-03-17 2007-01-02 Nexia Biotechnologies, Inc. Production of biofilaments in transgenic animals
WO2001056626A1 (en) * 2000-02-03 2001-08-09 Nexia Biotechnologies, Inc. Surgical sutures containing spider silk
US6608242B1 (en) * 2000-05-25 2003-08-19 E. I. Du Pont De Nemours And Company Production of silk-like proteins in plants
WO2001094393A2 (en) * 2000-06-09 2001-12-13 IPK Institut für Pflanzengenetik und Kulturpflanzenforschung Synthetic spider silk proteins and the expression thereof in transgenic plants
CA2351274C (en) * 2000-06-29 2011-04-26 Fiona F. Hunter Isolated cocoon silk protein from simulium vittatum and nucleic acids encoding such protein
US20110009960A1 (en) 2001-11-16 2011-01-13 Allergan, Inc. Prosthetic fabric structure
WO2003057720A2 (en) * 2002-01-11 2003-07-17 Nexia Biotechnologies, Inc. Recovery of biofilament proteins from biological fluids
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EP1601826B1 (en) 2003-03-11 2011-06-29 Allergan, Inc. Biocompatible silk fabric implant
EP3231846A1 (en) 2003-04-10 2017-10-18 Tufts University Concentrated aqueous silk fibroin solution and use thereof
BRPI0616894B8 (en) * 2005-10-05 2021-07-27 Commw Scient Ind Res Org recombinant silk polypeptide, exogenous polynucleotide, expression vector, bacterial or yeast host cell, process for preparing a silk polypeptide, product, composition, use and kit
CN101395178B (en) 2005-12-30 2013-05-01 思百博技术股份公司 Spider silk proteins and methods for producing spider silk proteins
US20100028451A1 (en) 2006-09-26 2010-02-04 Trustees Of Tufts College Silk microspheres for encapsulation and controlled release
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US9808557B2 (en) 2007-08-10 2017-11-07 Trustees Of Tufts College Tubular silk compositions and methods of use thereof
CA2713251A1 (en) * 2008-02-07 2009-08-13 Trustees Of Tufts College 3-dimensional silk hydroxyapatite compositions
WO2010042798A2 (en) 2008-10-09 2010-04-15 Trustees Of Tufts College Modified silk films containing glycerol
WO2010057142A2 (en) 2008-11-17 2010-05-20 Trustees Of Tufts College Surface modification of silk fibroin matrices with poly(ethylene glycol) useful as anti adhesion barriers and anti thrombotic materials
US9308070B2 (en) 2008-12-15 2016-04-12 Allergan, Inc. Pliable silk medical device
US20130245757A1 (en) 2011-11-04 2013-09-19 Allergan, Inc. Method and device for improved soft tissue surgery
WO2011005381A2 (en) 2009-06-01 2011-01-13 Trustees Of Tufts College Vortex-induced silk fibroin gelation for encapsulation and delivery
CA2803833A1 (en) 2009-07-20 2011-04-21 Tufts University/Trustees Of Tufts College All-protein implantable, resorbable reflectors
CA2773956A1 (en) 2009-09-11 2011-03-17 Allergan, Inc. Prosthetic device and method of manufacturing the same
WO2011109691A2 (en) 2010-03-05 2011-09-09 Trustees Of Tufts College Silk-based ionomeric compositions
JP2013533754A (en) 2010-04-12 2013-08-29 タフツ・ユニバーシティ Silk electronic parts
CN103200971B (en) 2010-08-30 2015-09-30 哈佛大学校长及研究员协会 Complex layered materials, its manufacture method and application thereof
EP2611492A2 (en) 2010-09-03 2013-07-10 Tufts University/Trustees of Tufts College Plasmonic nanoparticle-doped silk materials
JP5691052B2 (en) * 2010-09-10 2015-04-01 岡本株式会社 Recombinant organisms and proteins made by recombinant organisms
US9761789B2 (en) 2010-09-27 2017-09-12 Tufts University Silk-based piezoelectric materials
EP4218891A1 (en) 2010-10-19 2023-08-02 Trustees Of Tufts College Silk fibroin-based microneedles and methods of making the same
WO2012145652A1 (en) 2011-04-20 2012-10-26 Trustees Of Tufts College Dynamic silk coatings for implantable devices
WO2012145739A1 (en) 2011-04-21 2012-10-26 Trustees Of Tufts College Compositions and methods for stabilization of active agents
US20140370094A1 (en) 2011-11-08 2014-12-18 Tufts University Silk-based scaffold platform for engineering tissue constructs
MX2014005704A (en) 2011-11-09 2015-02-17 Tufts College Injectable silk fibroin foams and uses thereof.
KR20230066481A (en) 2011-11-09 2023-05-15 트러스티즈 오브 터프츠 칼리지 Injectable silk fibroin particles and uses thereof
US10126467B2 (en) 2011-12-05 2018-11-13 Tufts University Signal enhancement by silk photonic crystals
EP2797641B1 (en) 2011-12-29 2019-07-10 Trustees Of Tufts College Functionalization of biomaterials to control regeneration and inflammation responses
WO2013119551A1 (en) 2012-02-06 2013-08-15 Children's Medical Center Corporation Multi-layer biomaterial for tissue regeneration and wound healing
NL1039495C2 (en) * 2012-03-27 2013-09-30 Jalila Essaidi METHOD FOR MANUFACTURING A SKIN SUBSTITUTE BASED ON SPIDER SIDE AND WEAR STRUCTURE MANUFACTURED USING THIS METHOD AND WEAR STRUCTURE WITH GROWING LIVING SKIN.
CA2869967A1 (en) 2012-04-13 2013-10-17 Trustees Of Tufts College Methods and compositions for preparing a silk microsphere
WO2013163407A1 (en) 2012-04-25 2013-10-31 Trustees Of Tufts College Silk microspheres and methods for surface lubrication
US10034945B2 (en) 2012-07-13 2018-07-31 Trustees Of Tufts College Silk powder compaction for production of constructs with high mechanical strength and stiffness
WO2014035798A1 (en) 2012-08-30 2014-03-06 Sanofi Silk lyogels for sustained release of protein therapeutics and methods of making and uses
WO2014085725A1 (en) 2012-11-27 2014-06-05 Tufts University Biopolymer-based inks and use thereof
WO2014197093A2 (en) 2013-03-15 2014-12-11 Tufts University All water-based nanopatterning
US10464361B2 (en) 2013-03-15 2019-11-05 Tufts University Silk water lithography
KR102457668B1 (en) 2013-03-15 2022-10-21 트러스티즈 오브 터프츠 칼리지 Low molecular weight silk compositions and stabilizing silk compositions
US11376329B2 (en) 2013-03-15 2022-07-05 Trustees Of Tufts College Low molecular weight silk compositions and stabilizing silk compositions
JP6317425B2 (en) 2013-03-15 2018-04-25 パセオン ソフトジェルズ インコーポレイティド Silk capsule
CN103194068B (en) * 2013-04-08 2015-12-23 浙江大学 A kind of method of stable silk fibroin protein solution
US10285702B2 (en) 2013-04-24 2019-05-14 Trustees Of Tufts College Bioresorbable biopolymer anastomosis devices
US10925999B2 (en) 2013-10-08 2021-02-23 Trustees Of Tufts College Tunable covalently crosslinked hydrogels and methods of making the same
WO2015070108A1 (en) 2013-11-08 2015-05-14 Tufts University Peptide-based nanofibrillar materials
EP3113624A4 (en) 2014-03-07 2017-11-08 Tufts University Biopolymer-based preservation of perishable products
EP3147369A4 (en) * 2014-05-21 2018-02-07 Ajinomoto Co., Inc. Fibroin-like protein production method
WO2016028797A1 (en) 2014-08-18 2016-02-25 Allergan, Inc. Pliable silk medical device
US10758645B2 (en) 2014-12-17 2020-09-01 Tufts University Injectable, flexible hydroxyapatite-silk foams for osteochondral and dental repair
KR102625116B1 (en) 2015-03-12 2024-01-12 터프츠 유니버시티 shape memory silk material
CA2995233C (en) 2015-07-20 2024-01-02 Tufts University Biodegradable silk ear tubes
CN105231565B (en) * 2015-10-20 2018-01-16 杭州华水布艺有限公司 A kind of anti-stab protective fabric containing ice-cold material
WO2017123383A2 (en) 2015-12-17 2017-07-20 Trustees Of Tufts College Silk-fibroin hydrogels, methods of forming, and uses thereof
WO2017106631A1 (en) 2015-12-18 2017-06-22 Tufts University Silk solution purification system, concentrating system, and methods thereof
WO2017192227A1 (en) 2016-05-04 2017-11-09 Trustees Of Tufts College Silk nanofibrils and uses thereof
WO2018006037A1 (en) 2016-07-01 2018-01-04 Trustees Of Tufts College Innervated artificial skin
US11248313B2 (en) 2016-08-01 2022-02-15 Trustees Of Tufts College Biomimetic mechanical tension driven fabrication of nanofibrillar architecture
EP3532093A1 (en) 2016-09-19 2019-09-04 Vaxess Technologies, Inc. Vaccine formulations with increased stability
US11247181B2 (en) 2016-10-24 2022-02-15 Trustees Of Tufts College Biomimetic multilayer compositions
US10857262B2 (en) 2016-10-31 2020-12-08 Sofregen Medical, Inc. Compositions comprising low molecular weight silk fibroin fragments and plasticizers
WO2018136754A1 (en) 2017-01-20 2018-07-26 Massachusetts Institute Of Technology Injectable polymer micro-depots for controlled local drug delivery
US20200306163A1 (en) * 2017-09-27 2020-10-01 Evolved By Nature, Inc. Materials comprising recombinant silk and methods of preparing the same
US11419947B2 (en) 2017-10-30 2022-08-23 Massachusetts Institute Of Technology Layer-by-layer nanoparticles for cytokine therapy in cancer treatment
WO2019195350A1 (en) 2018-04-03 2019-10-10 Vaxess Technologies, Inc. Microneedle comprising silk fibroin applied to a dissolvable base
WO2020023906A2 (en) 2018-07-27 2020-01-30 Vaxess Technologies, Inc. Polymer-based biospecimen collection devices and uses thereof
JP2022513628A (en) * 2018-11-28 2022-02-09 ボルト スレッズ インコーポレイテッド Alkaline purification method for spider silk protein
CN110106571A (en) * 2019-04-09 2019-08-09 商文辉 A kind of spider web textile fabric and preparation method thereof
WO2021076798A1 (en) 2019-10-15 2021-04-22 Sofregen Medical, Inc. Delivery devices for delivering and methods of delivering compositions
US20240104583A1 (en) 2022-09-26 2024-03-28 Massachusetts Institute Of Technology Integrating Biopolymer Design with Physical Unclonable Functions for Anticounterfeiting and Product Traceability

Family Cites Families (2)

* Cited by examiner, † Cited by third party
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AU7691191A (en) * 1990-04-19 1991-11-11 United States Of America, As Represented By The Secretary Of The Army, The Recombinant spider silk proteins through genetic engineering
ATE189699T1 (en) * 1990-04-20 2000-02-15 Univ Wyoming DNA ENCODING SPIDER SILK PROTEIN, VECTOR CONTAINING DNA, TRANSFORMED CELL AND PRODUCTS THEREOF

Also Published As

Publication number Publication date
AU7152996A (en) 1997-03-19
WO1997008315A1 (en) 1997-03-06
EP0848754A1 (en) 1998-06-24
BR9612625A (en) 1999-06-01
CN1200145A (en) 1998-11-25
JPH11511325A (en) 1999-10-05

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