BRPI0612654B8 - método para conjugar um sacarídeo a uma proteína, e, conjugado sacarídeo-proteína - Google Patents

método para conjugar um sacarídeo a uma proteína, e, conjugado sacarídeo-proteína

Info

Publication number
BRPI0612654B8
BRPI0612654B8 BRPI0612654A BRPI0612654A BRPI0612654B8 BR PI0612654 B8 BRPI0612654 B8 BR PI0612654B8 BR PI0612654 A BRPI0612654 A BR PI0612654A BR PI0612654 A BRPI0612654 A BR PI0612654A BR PI0612654 B8 BRPI0612654 B8 BR PI0612654B8
Authority
BR
Brazil
Prior art keywords
saccharide
protein
immunogenic composition
vaccine
conjugate
Prior art date
Application number
BRPI0612654A
Other languages
English (en)
Portuguese (pt)
Inventor
Duvivier Pierre
Leon Biemans Ralph
Original Assignee
Glaxosmithkline Biologicals Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36716943&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0612654(B8) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GBGB0513071.1A external-priority patent/GB0513071D0/en
Priority claimed from GBGB0513069.5A external-priority patent/GB0513069D0/en
Priority claimed from GB0515556A external-priority patent/GB0515556D0/en
Priority claimed from GB0524204A external-priority patent/GB0524204D0/en
Priority claimed from GB0526041A external-priority patent/GB0526041D0/en
Priority claimed from GB0526040A external-priority patent/GB0526040D0/en
Application filed by Glaxosmithkline Biologicals Sa filed Critical Glaxosmithkline Biologicals Sa
Publication of BRPI0612654A2 publication Critical patent/BRPI0612654A2/pt
Publication of BRPI0612654B1 publication Critical patent/BRPI0612654B1/pt
Publication of BRPI0612654B8 publication Critical patent/BRPI0612654B8/pt

Links

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0016—Combination vaccines based on diphtheria-tetanus-pertussis
    • A61K39/0017—Combination vaccines based on whole cell diphtheria-tetanus-pertussis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K39/02—Bacterial antigens
    • A61K39/095—Neisseria
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    • A61K39/0016—Combination vaccines based on diphtheria-tetanus-pertussis
    • A61K39/0018—Combination vaccines based on acellular diphtheria-tetanus-pertussis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K39/02—Bacterial antigens
    • A61K39/05—Actinobacteria, e.g. Actinomyces, Streptomyces, Nocardia, Bifidobacterium, Gardnerella, Corynebacterium; Propionibacterium
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K39/02—Bacterial antigens
    • A61K39/08—Clostridium, e.g. Clostridium tetani
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092—Streptococcus
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A—HUMAN NECESSITIES
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    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/575—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 humoral response
    • A—HUMAN NECESSITIES
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
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    • A61K2039/62—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/62—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier
    • A61K2039/627—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier characterised by the linker
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K2039/70—Multivalent vaccine
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    • C12N2730/10011—Hepadnaviridae
    • C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
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    • C12N2760/16234—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16211—Influenzavirus B, i.e. influenza B virus
    • C12N2760/16271—Demonstrated in vivo effect
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    • C12N2770/00011—Details
    • C12N2770/32011—Picornaviridae
    • C12N2770/32611—Poliovirus
    • C12N2770/32634—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Oncology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Otolaryngology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Surgical Instruments (AREA)
BRPI0612654A 2005-06-27 2006-06-23 método para conjugar um sacarídeo a uma proteína, e, conjugado sacarídeo-proteína BRPI0612654B8 (pt)

Applications Claiming Priority (13)

Application Number Priority Date Filing Date Title
GBGB0513071.1A GB0513071D0 (en) 2005-06-27 2005-06-27 Immunogenic composition
GBGB0513069.5A GB0513069D0 (en) 2005-06-27 2005-06-27 Immunogenic composition
GB0513069.5 2005-06-27
GB0513071.1 2005-06-27
GB0515556.9 2005-07-28
GB0515556A GB0515556D0 (en) 2005-07-28 2005-07-28 Immunogenic composition
GB0524204.5 2005-11-28
GB0524204A GB0524204D0 (en) 2005-11-28 2005-11-28 Immunogenic composition
GB0526041A GB0526041D0 (en) 2005-12-21 2005-12-21 Immunogenic composition
GB0526041.9 2005-12-21
GB0526040.1 2005-12-21
GB0526040A GB0526040D0 (en) 2005-12-21 2005-12-21 Immunogenic composition
PCT/EP2006/006270 WO2007000343A2 (en) 2005-06-27 2006-06-23 Process for manufacturing vaccines

Publications (3)

Publication Number Publication Date
BRPI0612654A2 BRPI0612654A2 (pt) 2012-10-02
BRPI0612654B1 BRPI0612654B1 (pt) 2021-05-04
BRPI0612654B8 true BRPI0612654B8 (pt) 2021-05-25

Family

ID=36716943

Family Applications (5)

Application Number Title Priority Date Filing Date
BRPI0612670A BRPI0612670B8 (pt) 2005-06-27 2006-06-23 composição imunogênica, vacina a compreendendo e kit de vacina para a administração concomitante ou sequencial
BRPI0612655-3A BRPI0612655B1 (pt) 2005-06-27 2006-06-23 Composição imunogênica
BRPI0612669A BRPI0612669B8 (pt) 2005-06-27 2006-06-23 composição imunogênica, vacina, composição, e composição liofilizada
BRPI0612656-1A BRPI0612656B1 (pt) 2005-06-27 2006-06-23 Composição imunogênica, vacina, e, kit de vacina para a administração concomitante ou sequencial
BRPI0612654A BRPI0612654B8 (pt) 2005-06-27 2006-06-23 método para conjugar um sacarídeo a uma proteína, e, conjugado sacarídeo-proteína

Family Applications Before (4)

Application Number Title Priority Date Filing Date
BRPI0612670A BRPI0612670B8 (pt) 2005-06-27 2006-06-23 composição imunogênica, vacina a compreendendo e kit de vacina para a administração concomitante ou sequencial
BRPI0612655-3A BRPI0612655B1 (pt) 2005-06-27 2006-06-23 Composição imunogênica
BRPI0612669A BRPI0612669B8 (pt) 2005-06-27 2006-06-23 composição imunogênica, vacina, composição, e composição liofilizada
BRPI0612656-1A BRPI0612656B1 (pt) 2005-06-27 2006-06-23 Composição imunogênica, vacina, e, kit de vacina para a administração concomitante ou sequencial

Country Status (36)

Country Link
US (13) US9486515B2 (enExample)
EP (11) EP1896062B1 (enExample)
JP (9) JP5280199B2 (enExample)
KR (7) KR101532068B1 (enExample)
CN (3) CN102218138A (enExample)
AP (1) AP2436A (enExample)
AR (3) AR053935A1 (enExample)
AT (3) ATE536884T1 (enExample)
AU (7) AU2006263963B2 (enExample)
BE (1) BE2012C042I2 (enExample)
BR (5) BRPI0612670B8 (enExample)
CA (5) CA2612957C (enExample)
CY (5) CY1109996T1 (enExample)
DE (1) DE602006013313D1 (enExample)
DK (7) DK2351578T3 (enExample)
EA (4) EA012214B1 (enExample)
ES (9) ES2377075T5 (enExample)
FR (1) FR22C1008I2 (enExample)
HR (4) HRP20100211T1 (enExample)
HU (7) HUE047211T2 (enExample)
IL (8) IL187924A (enExample)
LT (2) LT2351578T (enExample)
LU (2) LU92085I2 (enExample)
MA (4) MA29603B1 (enExample)
MX (5) MX2007016402A (enExample)
MY (3) MY148110A (enExample)
NL (2) NL300549I2 (enExample)
NO (4) NO345422B1 (enExample)
NZ (6) NZ564606A (enExample)
PE (6) PE20110096A1 (enExample)
PL (8) PL1896061T3 (enExample)
PT (8) PT3009146T (enExample)
SI (8) SI1896063T1 (enExample)
TW (5) TWI407970B (enExample)
UA (2) UA95237C2 (enExample)
WO (6) WO2007000343A2 (enExample)

Families Citing this family (104)

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OA12302A (en) * 2000-06-29 2003-10-24 Glaxosmithkline Biolog Sa Multivalent vaccine composition.
MX339524B (es) 2001-10-11 2016-05-30 Wyeth Corp Composiciones inmunogenicas novedosas para la prevencion y tratamiento de enfermedad meningococica.
DK1587537T3 (da) 2003-01-30 2012-07-16 Novartis Ag Injicerbare vacciner mod multiple meningococ-serogrupper
GB0408977D0 (en) * 2004-04-22 2004-05-26 Chiron Srl Immunising against meningococcal serogroup Y using proteins
GB0505518D0 (en) * 2005-03-17 2005-04-27 Chiron Srl Combination vaccines with whole cell pertussis antigen
US7955605B2 (en) * 2005-04-08 2011-06-07 Wyeth Llc Multivalent pneumococcal polysaccharide-protein conjugate composition
US9486515B2 (en) 2005-06-27 2016-11-08 Glaxosmithkline Biologicals S.A. Immunogenic composition
CA2621023C (en) 2005-09-01 2019-07-02 Novartis Vaccines And Diagnostics Gmbh & Co. Kg Multiple vaccination including serogroup c meningococcus
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EP1896064A2 (en) 2008-03-12
JP2008543908A (ja) 2008-12-04
JP2008543909A (ja) 2008-12-04
IL188072A0 (en) 2008-03-20
BE2012C042I2 (enExample) 2021-07-19
US9358279B2 (en) 2016-06-07
IL213718A (en) 2013-07-31
US9486515B2 (en) 2016-11-08
KR20130122810A (ko) 2013-11-08
EP1896061A2 (en) 2008-03-12
EP1896065A2 (en) 2008-03-12
EP3009146A1 (en) 2016-04-20
TW200738259A (en) 2007-10-16
IL187924A (en) 2011-11-30
IL213795A0 (en) 2011-07-31
CY1118646T1 (el) 2017-07-12
NL301151I2 (nl) 2025-12-15
HRP20110567T1 (en) 2011-09-30
PT2283857T (pt) 2019-10-24
EA200702575A1 (ru) 2008-06-30
CA2611964C (en) 2016-11-08
MX2007016403A (es) 2008-03-07
IL187924A0 (en) 2008-03-20
CY2012027I1 (el) 2015-10-07
SI2351578T1 (sl) 2017-05-31
AU2006263936A1 (en) 2007-01-04
AU2010203115C1 (en) 2013-05-02
AU2010203115B2 (en) 2012-03-15
AU2006263964A1 (en) 2007-01-04
BRPI0612655A2 (pt) 2010-11-30
US20090041802A1 (en) 2009-02-12
PE20110072A1 (es) 2011-02-04
MX2007016405A (es) 2008-03-07
CA2612980C (en) 2019-01-15
US8431136B2 (en) 2013-04-30
BRPI0612669B8 (pt) 2021-05-25
ES2377075T5 (es) 2016-04-29
SI1896062T1 (sl) 2010-07-30
BRPI0612656A8 (pt) 2018-01-23
EA200702574A1 (ru) 2008-06-30
KR20080030577A (ko) 2008-04-04
EP1896063A1 (en) 2008-03-12
SI3009146T1 (sl) 2022-02-28
CA2612963A1 (en) 2007-01-04
NL300549I2 (enExample) 2017-01-03
PL2283857T3 (pl) 2020-02-28
KR101408113B1 (ko) 2014-06-16
SI2878307T1 (sl) 2019-11-29
TWI407970B (zh) 2013-09-11
WO2007000327A1 (en) 2007-01-04
US20170065714A1 (en) 2017-03-09
AU2010212417A1 (en) 2010-09-09
EA200702576A1 (ru) 2008-06-30
US8398983B2 (en) 2013-03-19
DE602006013313D1 (de) 2010-05-12
IL188046A (en) 2012-03-29
KR101359953B1 (ko) 2014-02-21
EA012506B1 (ru) 2009-10-30
DK1896065T3 (da) 2011-08-29
EP2283857B1 (en) 2019-07-24
KR101532068B1 (ko) 2015-06-29
US8846049B2 (en) 2014-09-30
PT2878307T (pt) 2019-10-24
PE20070499A1 (es) 2007-05-21
PT1896063E (pt) 2012-02-13
US20150044253A1 (en) 2015-02-12
TWI422386B (zh) 2014-01-11

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