BRPI0408247A - usos de antagonistas e agonistas de il-23 e reagentes relacionados - Google Patents

usos de antagonistas e agonistas de il-23 e reagentes relacionados

Info

Publication number
BRPI0408247A
BRPI0408247A BRPI0408247-8A BRPI0408247A BRPI0408247A BR PI0408247 A BRPI0408247 A BR PI0408247A BR PI0408247 A BRPI0408247 A BR PI0408247A BR PI0408247 A BRPI0408247 A BR PI0408247A
Authority
BR
Brazil
Prior art keywords
agonists
antagonists
related reagents
methods
reagents
Prior art date
Application number
BRPI0408247-8A
Other languages
English (en)
Inventor
Martin Oft
Terrill K Mcclanahan
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of BRPI0408247A publication Critical patent/BRPI0408247A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7155—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Pain & Pain Management (AREA)
  • Nutrition Science (AREA)
  • Rheumatology (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

"USOS DE ANTAGONISTAS E AGONISTAS DE IL-23 E REAGENTES RELACIONADOS". A presente invenção refere-se a métodos de tratamento para tumores. Em particular, métodos que são providos para a modulação de atividade de uma molécula de citocina e seu receptor.
BRPI0408247-8A 2003-03-10 2004-03-09 usos de antagonistas e agonistas de il-23 e reagentes relacionados BRPI0408247A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US45367203P 2003-03-10 2003-03-10
PCT/US2004/007198 WO2004081190A2 (en) 2003-03-10 2004-03-09 Uses of il-23 agonists and antagonists; related reagents

Publications (1)

Publication Number Publication Date
BRPI0408247A true BRPI0408247A (pt) 2006-03-01

Family

ID=32990805

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0408247-8A BRPI0408247A (pt) 2003-03-10 2004-03-09 usos de antagonistas e agonistas de il-23 e reagentes relacionados

Country Status (23)

Country Link
US (4) US7282204B2 (pt)
EP (2) EP2108658B1 (pt)
JP (4) JP4605798B2 (pt)
CN (1) CN1759123B (pt)
AT (1) ATE440864T1 (pt)
AU (2) AU2004219625B9 (pt)
BR (1) BRPI0408247A (pt)
CA (1) CA2518262C (pt)
CL (1) CL2004000467A1 (pt)
CY (1) CY1109468T1 (pt)
DE (1) DE602004022781D1 (pt)
DK (1) DK1601694T3 (pt)
ES (1) ES2330220T3 (pt)
HK (1) HK1076477A1 (pt)
MX (1) MXPA05009717A (pt)
NO (1) NO20054630L (pt)
NZ (2) NZ541898A (pt)
PL (1) PL1601694T3 (pt)
PT (1) PT1601694E (pt)
SI (1) SI1601694T1 (pt)
TW (2) TWI357336B (pt)
WO (1) WO2004081190A2 (pt)
ZA (1) ZA200506879B (pt)

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ATE533502T1 (de) * 2004-02-17 2011-12-15 Schering Corp Verfahren zur modulation der il-23-aktivität; relevante reagenzien
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US20060193821A1 (en) * 2004-03-05 2006-08-31 Diener John L Aptamers to the human IL-12 cytokine family and their use as autoimmune disease therapeutics
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US7820168B2 (en) 2004-12-20 2010-10-26 Schering Corporation Treatment of diabetes using antibodies to IL-23, IL-23 receptor and IL-17
EP1896073B1 (en) 2005-06-30 2013-03-06 Janssen Biotech, Inc. Anti-il-23 antibodies, compositions, methods and uses
EP1910414A4 (en) * 2005-06-30 2009-02-11 Archemix Corp POLYNUCLEOTIDES AND POLYPEPTIDES OF THE CYTOKINE IL-12 FAMILY
AU2012258409B2 (en) * 2005-06-30 2016-01-07 Centocor, Inc. Anti-IL-23 antibodies, compositions, methods and uses
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ES2619845T3 (es) 2005-08-31 2017-06-27 Merck Sharp & Dohme Corp. Anticuerpos anti-IL-23 diseñados por ingeniería genética
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JPWO2009054454A1 (ja) 2007-10-24 2011-03-03 国立大学法人 東京医科歯科大学 カテプシン阻害剤を有効成分として含有するＴｏｌｌ様受容体のシグナル伝達の調整剤
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Also Published As

Publication number Publication date
ES2330220T3 (es) 2009-12-07
AU2004219625B9 (en) 2010-12-23
WO2004081190A3 (en) 2005-02-03
AU2010212372A1 (en) 2010-09-09
TWI439285B (zh) 2014-06-01
NZ567860A (en) 2009-11-27
US7282204B2 (en) 2007-10-16
EP2108658B1 (en) 2016-06-08
CY1109468T1 (el) 2014-08-13
CN1759123A (zh) 2006-04-12
AU2010212372B2 (en) 2012-12-20
JP2007197453A (ja) 2007-08-09
AU2004219625B2 (en) 2010-08-19
US20120034219A1 (en) 2012-02-09
WO2004081190A2 (en) 2004-09-23
AU2004219625A1 (en) 2004-09-23
EP2108658A1 (en) 2009-10-14
PT1601694E (pt) 2009-12-03
DE602004022781D1 (de) 2009-10-08
JP2006520781A (ja) 2006-09-14
NO20054630D0 (no) 2005-10-07
TW200505479A (en) 2005-02-16
EP1601694B1 (en) 2009-08-26
NZ541898A (en) 2008-07-31
PL1601694T3 (pl) 2010-02-26
NO20054630L (no) 2005-10-07
SI1601694T1 (sl) 2010-01-29
CA2518262A1 (en) 2004-09-23
EP1601694A2 (en) 2005-12-07
JP4605798B2 (ja) 2011-01-05
TW201141521A (en) 2011-12-01
CA2518262C (en) 2014-05-06
US20040223969A1 (en) 2004-11-11
US20100003251A1 (en) 2010-01-07
US8034341B2 (en) 2011-10-11
HK1076477A1 (en) 2006-01-20
JP2011032275A (ja) 2011-02-17
JP2014005286A (ja) 2014-01-16
US20080057058A1 (en) 2008-03-06
CL2004000467A1 (es) 2005-05-06
ATE440864T1 (de) 2009-09-15
MXPA05009717A (es) 2005-10-18
ZA200506879B (en) 2006-05-31
DK1601694T3 (da) 2009-12-14
CN1759123B (zh) 2011-04-13
TWI357336B (en) 2012-02-01

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