BRPI0412411A - tetrahidro-1h-pirazol[3,4-c]piridinas substituìdas, composições que as contêm e utilização - Google Patents

tetrahidro-1h-pirazol[3,4-c]piridinas substituìdas, composições que as contêm e utilização

Info

Publication number
BRPI0412411A
BRPI0412411A BRPI0412411-1A BRPI0412411A BRPI0412411A BR PI0412411 A BRPI0412411 A BR PI0412411A BR PI0412411 A BRPI0412411 A BR PI0412411A BR PI0412411 A BRPI0412411 A BR PI0412411A
Authority
BR
Brazil
Prior art keywords
pyridines
pyrazol
compositions containing
substituted tetrahydro
substituted
Prior art date
Application number
BRPI0412411-1A
Other languages
English (en)
Inventor
Fabienne Thompson
Patrick Mailliet
Teresa Damiano
Marie-Pierre Cherrier
Francois Clerc
Franck Halley
Herve Bouchard
Laurence Gauzy-Lazo
Bernard Baudoin
Catherine Souaille
Fabrice Viviani
Michel Tabart
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR0308442A external-priority patent/FR2857363B1/fr
Priority claimed from FR0308441A external-priority patent/FR2857362B1/fr
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Publication of BRPI0412411A publication Critical patent/BRPI0412411A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

"TETRAHIDRO-1H-PIRAZOL¢3,4-C!PIRIDINAS SUBSTITUìDAS, COMPOSIçõES QUE AS CONTêM E UTILIZAçãO". A presente invenção refere-se a tetrahidro-1H-pirazol¢3,4-c!piridinas substituídas, composições que as contêm e utilização. A presente invenção refere-se notadamente às novas tetrahidro-1H-pirazol¢3,4-c!piridinas substituídas, tendo uma atividade terapêutica, utilizáveis em particular em oncologia.
BRPI0412411-1A 2003-07-10 2004-07-08 tetrahidro-1h-pirazol[3,4-c]piridinas substituìdas, composições que as contêm e utilização BRPI0412411A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0308442A FR2857363B1 (fr) 2003-07-10 2003-07-10 4,5,6,7-tetrahydro-1h-pyrazolo[3,4-c] pyridines substituees compositions les contenant et utilisation
FR0308441A FR2857362B1 (fr) 2003-07-10 2003-07-10 Tetrahydro-1h-pyrazolo[3,4-c] pyridines substituees, compositions les contenant et utilisation
PCT/FR2004/001778 WO2005007653A2 (fr) 2003-07-10 2004-07-08 Tetrahydro-1h-pyrazolo[3,4-c]pyridines substituees, compositions les contenant et utilisation

Publications (1)

Publication Number Publication Date
BRPI0412411A true BRPI0412411A (pt) 2006-08-22

Family

ID=34081983

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0412411-1A BRPI0412411A (pt) 2003-07-10 2004-07-08 tetrahidro-1h-pirazol[3,4-c]piridinas substituìdas, composições que as contêm e utilização

Country Status (12)

Country Link
US (2) US7109340B2 (pt)
EP (2) EP2251340A1 (pt)
JP (1) JP4740841B2 (pt)
KR (1) KR20060054291A (pt)
AR (1) AR045037A1 (pt)
AU (1) AU2004256945B2 (pt)
BR (1) BRPI0412411A (pt)
CA (1) CA2532122A1 (pt)
IL (1) IL172994A0 (pt)
MX (1) MXPA06000247A (pt)
TW (1) TW200519110A (pt)
WO (1) WO2005007653A2 (pt)

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KR102429220B1 (ko) 2014-04-30 2022-08-04 더 트러스티이스 오브 콜롬비아 유니버시티 인 더 시티 오브 뉴욕 치환 4-페닐피페리딘, 그 제조 및 사용
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US10851105B2 (en) 2014-10-22 2020-12-01 Incyte Corporation Bicyclic heterocycles as FGFR4 inhibitors
MA41551A (fr) 2015-02-20 2017-12-26 Incyte Corp Hétérocycles bicycliques utilisés en tant qu'inhibiteurs de fgfr4
CN113004278B (zh) 2015-02-20 2023-07-21 因赛特控股公司 作为fgfr抑制剂的双环杂环
WO2016134294A1 (en) 2015-02-20 2016-08-25 Incyte Corporation Bicyclic heterocycles as fgfr4 inhibitors
AR111960A1 (es) 2017-05-26 2019-09-04 Incyte Corp Formas cristalinas de un inhibidor de fgfr y procesos para su preparación
WO2019213544A2 (en) 2018-05-04 2019-11-07 Incyte Corporation Solid forms of an fgfr inhibitor and processes for preparing the same
CR20200591A (es) 2018-05-04 2021-03-31 Incyte Corp Sales de un inhibidor de fgfr
WO2020065614A1 (en) 2018-09-28 2020-04-02 Janssen Pharmaceutica Nv Monoacylglycerol lipase modulators
KR20210069080A (ko) 2018-09-28 2021-06-10 얀센 파마슈티카 엔.브이. 모노아실글리세롤 리파아제 조절제
WO2020185532A1 (en) 2019-03-08 2020-09-17 Incyte Corporation Methods of treating cancer with an fgfr inhibitor
WO2021007269A1 (en) 2019-07-09 2021-01-14 Incyte Corporation Bicyclic heterocycles as fgfr inhibitors
CN114555596A (zh) 2019-09-30 2022-05-27 詹森药业有限公司 放射性标记的mgl pet配体
TW202128685A (zh) 2019-10-14 2021-08-01 美商英塞特公司 作為ｆｇｆｒ抑制劑之雙環雜環
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Also Published As

Publication number Publication date
KR20060054291A (ko) 2006-05-22
US7435820B2 (en) 2008-10-14
US20050096345A1 (en) 2005-05-05
TW200519110A (en) 2005-06-16
EP1646632A2 (fr) 2006-04-19
US7109340B2 (en) 2006-09-19
JP2007516186A (ja) 2007-06-21
IL172994A0 (en) 2006-06-11
EP2251340A1 (fr) 2010-11-17
WO2005007653A2 (fr) 2005-01-27
MXPA06000247A (es) 2006-03-30
AU2004256945B2 (en) 2009-08-20
US20060199837A1 (en) 2006-09-07
CA2532122A1 (fr) 2005-01-27
AR045037A1 (es) 2005-10-12
AU2004256945A1 (en) 2005-01-27
WO2005007653A3 (fr) 2005-03-24
JP4740841B2 (ja) 2011-08-03

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B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

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B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2159 DE 22/05/2012.