MXPA05011522A - Derivados de 2-acilamino-4-feniltiazol, metodo para su preparacion y su aplicacion en terapeutica. - Google Patents
Derivados de 2-acilamino-4-feniltiazol, metodo para su preparacion y su aplicacion en terapeutica.Info
- Publication number
- MXPA05011522A MXPA05011522A MXPA05011522A MXPA05011522A MXPA05011522A MX PA05011522 A MXPA05011522 A MX PA05011522A MX PA05011522 A MXPA05011522 A MX PA05011522A MX PA05011522 A MXPA05011522 A MX PA05011522A MX PA05011522 A MXPA05011522 A MX PA05011522A
- Authority
- MX
- Mexico
- Prior art keywords
- phenylthiazole
- acylamino
- therapeutics
- derivatives
- preparation
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/44—Acylated amino or imino radicals
- C07D277/46—Acylated amino or imino radicals by carboxylic acids, or sulfur or nitrogen analogues thereof
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/10—Spiro-condensed systems
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- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Virology (AREA)
- Pulmonology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Hematology (AREA)
- Rheumatology (AREA)
- Cardiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Obesity (AREA)
- Dermatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Biomedical Technology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Heart & Thoracic Surgery (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Hospice & Palliative Care (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Pain & Pain Management (AREA)
- Child & Adolescent Psychology (AREA)
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Abstract
La invencion se refiere a derivados de 2-acilamino-4-feniltiazol, que tienen la formula general (I). La invencion se refiere tambien al metodo de preparacion de los mismos y a la aplicacion de los mismos en terapeutica.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0305213A FR2854158B1 (fr) | 2003-04-25 | 2003-04-25 | Derives de 2-acylamino-4-phenylethiazole, leur preparation et leur application en therapeutique |
PCT/FR2004/000981 WO2004096798A2 (fr) | 2003-04-25 | 2004-04-22 | Derives de 2-acylamino-4-phenylthiazole, leur preparation et leur application en therapeutique |
Publications (1)
Publication Number | Publication Date |
---|---|
MXPA05011522A true MXPA05011522A (es) | 2006-01-23 |
Family
ID=33104460
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MXPA05011522A MXPA05011522A (es) | 2003-04-25 | 2004-04-22 | Derivados de 2-acilamino-4-feniltiazol, metodo para su preparacion y su aplicacion en terapeutica. |
Country Status (24)
Country | Link |
---|---|
US (2) | US7504511B2 (es) |
EP (1) | EP1656373B1 (es) |
JP (2) | JP4839208B2 (es) |
KR (1) | KR20060006935A (es) |
CN (1) | CN1826339A (es) |
AR (1) | AR044070A1 (es) |
AT (1) | ATE541843T1 (es) |
AU (1) | AU2004234101A1 (es) |
BR (1) | BRPI0409716A (es) |
CA (1) | CA2521158A1 (es) |
CO (1) | CO5640106A2 (es) |
CR (1) | CR8037A (es) |
EC (1) | ECSP056111A (es) |
FR (1) | FR2854158B1 (es) |
MA (1) | MA27769A1 (es) |
MX (1) | MXPA05011522A (es) |
NO (1) | NO20054905L (es) |
OA (1) | OA13049A (es) |
RS (1) | RS20050769A (es) |
RU (1) | RU2348630C2 (es) |
TN (1) | TNSN05254A1 (es) |
TW (1) | TW200510325A (es) |
WO (1) | WO2004096798A2 (es) |
ZA (1) | ZA200508608B (es) |
Families Citing this family (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JO2527B1 (en) * | 2004-04-06 | 2010-03-17 | شركة جانسين فارماسوتيكا ان. في | Derivatives of second-aza-Spiro- (5,5) -andecan and their use as antihistamines |
JO2676B1 (en) * | 2004-04-06 | 2012-06-17 | جانسين فارماسوتيكا ان. في | Derivatives of second-aza-spiro- (5,4) -dikan and their use as antihistamines |
FR2872813B1 (fr) | 2004-07-09 | 2007-01-19 | Sanofi Synthelabo | Derives de 2-carbamide-4-phenylthiazole, leur preparation et leur application en therapeutique |
GB0421908D0 (en) * | 2004-10-01 | 2004-11-03 | Angeletti P Ist Richerche Bio | New uses |
FR2876692B1 (fr) * | 2004-10-19 | 2007-02-23 | Sanofi Aventis Sa | Derives de 2-amido-4-phenylthiazole, leur preparation et leur application en therapeutique |
JP2008526777A (ja) * | 2005-01-05 | 2008-07-24 | ライジェル ファーマシューティカルズ, インコーポレイテッド | ユビキチンリガーゼインヒビター |
ES2350647T3 (es) | 2005-03-08 | 2011-01-25 | Janssen Pharmaceutica Nv | Derivados de diaza-espiro-[4.4]-nonano como antagonistas de neuroquininas (nk1). |
UA92746C2 (en) | 2005-05-09 | 2010-12-10 | Акилайон Фармасьютикалз, Инк. | Thiazole compounds and methods of use |
US8067457B2 (en) | 2005-11-01 | 2011-11-29 | Millennium Pharmaceuticals, Inc. | Compounds useful as antagonists of CCR2 |
US20100016289A1 (en) * | 2005-11-01 | 2010-01-21 | Kevin Sprott | Compounds Useful as Antagonists of CCR2 |
US8067415B2 (en) | 2005-11-01 | 2011-11-29 | Millennium Pharmaceuticals, Inc. | Compounds useful as antagonists of CCR2 |
FR2895989B1 (fr) | 2006-01-06 | 2010-04-30 | Sanofi Aventis | Derives de 2-carbamide-4-phenylthiazole, leur preparation et leur application en therapeutique |
US20090124636A1 (en) * | 2006-04-12 | 2009-05-14 | Pfizer Inc. | Chemical compounds |
CN101096363B (zh) * | 2006-06-27 | 2011-05-11 | 中国人民解放军军事医学科学院毒物药物研究所 | 2,4,5-三取代噻唑类化合物、其制备方法、药物组合物及其制药用途 |
US20080076120A1 (en) * | 2006-09-14 | 2008-03-27 | Millennium Pharmaceuticals, Inc. | Methods for the identification, evaluation and treatment of patients having CC-Chemokine receptor 2 (CCR-2) mediated disorders |
US8754107B2 (en) | 2006-11-17 | 2014-06-17 | Abbvie Inc. | Aminopyrrolidines as chemokine receptor antagonists |
WO2008098949A2 (en) * | 2007-02-13 | 2008-08-21 | Ab Science | Process for the synthesis of 2-aminothiazole compounds as kinase inhibitors |
WO2008124000A2 (en) * | 2007-04-02 | 2008-10-16 | Ligand Pharmaceuticals Incorporated | Thiazole derivatives as androgen receptor modulator compounds |
CA2687931C (en) | 2007-05-31 | 2016-05-24 | Boehringer Ingelheim International Gmbh | Ccr2 receptor antagonists and uses thereof |
KR20100027243A (ko) * | 2007-07-31 | 2010-03-10 | 시오노기세이야쿠가부시키가이샤 | 트롬보포이에틴 수용체 아고니스트 작용을 갖는 광학 활성인 화합물을 함유하는 의약 조성물 및 그 중간체 |
PE20120061A1 (es) | 2008-12-19 | 2012-02-19 | Boehringer Ingelheim Int | Derivados de pirimidina como antagonistas del receptor ccr2 |
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2003
- 2003-04-25 FR FR0305213A patent/FR2854158B1/fr not_active Expired - Fee Related
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2004
- 2004-04-22 BR BRPI0409716-5A patent/BRPI0409716A/pt not_active IP Right Cessation
- 2004-04-22 JP JP2006505808A patent/JP4839208B2/ja not_active Expired - Fee Related
- 2004-04-22 KR KR1020057020168A patent/KR20060006935A/ko not_active Application Discontinuation
- 2004-04-22 AU AU2004234101A patent/AU2004234101A1/en not_active Abandoned
- 2004-04-22 AT AT04742558T patent/ATE541843T1/de active
- 2004-04-22 WO PCT/FR2004/000981 patent/WO2004096798A2/fr active Search and Examination
- 2004-04-22 ZA ZA200508608A patent/ZA200508608B/en unknown
- 2004-04-22 CN CNA2004800180511A patent/CN1826339A/zh active Pending
- 2004-04-22 RS YUP-2005/0769A patent/RS20050769A/sr unknown
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- 2004-04-22 CA CA002521158A patent/CA2521158A1/fr not_active Abandoned
- 2004-04-22 RU RU2005136663/04A patent/RU2348630C2/ru not_active IP Right Cessation
- 2004-04-22 EP EP04742558A patent/EP1656373B1/fr not_active Expired - Lifetime
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2005
- 2005-10-06 TN TNP2005000254A patent/TNSN05254A1/en unknown
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Also Published As
Publication number | Publication date |
---|---|
JP4839208B2 (ja) | 2011-12-21 |
NO20054905L (no) | 2006-01-25 |
RU2348630C2 (ru) | 2009-03-10 |
CR8037A (es) | 2008-07-29 |
EP1656373A2 (fr) | 2006-05-17 |
OA13049A (fr) | 2006-11-10 |
FR2854158B1 (fr) | 2006-11-17 |
US7777041B2 (en) | 2010-08-17 |
CO5640106A2 (es) | 2006-05-31 |
US7504511B2 (en) | 2009-03-17 |
ZA200508608B (en) | 2007-01-31 |
ATE541843T1 (de) | 2012-02-15 |
KR20060006935A (ko) | 2006-01-20 |
CA2521158A1 (fr) | 2004-11-11 |
US20060135575A1 (en) | 2006-06-22 |
CN1826339A (zh) | 2006-08-30 |
FR2854158A1 (fr) | 2004-10-29 |
TNSN05254A1 (en) | 2007-07-10 |
WO2004096798A3 (fr) | 2006-01-26 |
RS20050769A (en) | 2007-11-15 |
RU2005136663A (ru) | 2006-03-20 |
AR044070A1 (es) | 2005-08-24 |
JP2006524669A (ja) | 2006-11-02 |
EP1656373B1 (fr) | 2012-01-18 |
NO20054905D0 (no) | 2005-10-24 |
WO2004096798A2 (fr) | 2004-11-11 |
ECSP056111A (es) | 2006-03-01 |
MA27769A1 (fr) | 2006-02-01 |
TW200510325A (en) | 2005-03-16 |
BRPI0409716A (pt) | 2006-05-02 |
AU2004234101A1 (en) | 2004-11-11 |
US20090156574A1 (en) | 2009-06-18 |
JP2011126891A (ja) | 2011-06-30 |
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