PL1668001T3 - Podstawione heteroarylobenzofuranowe kwasy - Google Patents

Podstawione heteroarylobenzofuranowe kwasy

Info

Publication number
PL1668001T3
PL1668001T3 PL04784968T PL04784968T PL1668001T3 PL 1668001 T3 PL1668001 T3 PL 1668001T3 PL 04784968 T PL04784968 T PL 04784968T PL 04784968 T PL04784968 T PL 04784968T PL 1668001 T3 PL1668001 T3 PL 1668001T3
Authority
PL
Poland
Prior art keywords
substituted heteroaryl
heteroaryl benzofuran
benzofuran acids
acids
methods
Prior art date
Application number
PL04784968T
Other languages
English (en)
Inventor
Hassan Mahmoud Elokdah
Geraldine Ruth Mcfarlane
Scott Christian Mayer
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of PL1668001T3 publication Critical patent/PL1668001T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
PL04784968T 2003-09-25 2004-09-24 Podstawione heteroarylobenzofuranowe kwasy PL1668001T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US50601203P 2003-09-25 2003-09-25
US10/947,840 US7446201B2 (en) 2003-09-25 2004-09-23 Substituted heteroaryl benzofuran acids
EP04784968A EP1668001B1 (en) 2003-09-25 2004-09-24 Substituted heteroaryl benzofuran acids
PCT/US2004/031364 WO2005030760A1 (en) 2003-09-25 2004-09-24 Substituted heteroaryl benzofuran acids

Publications (1)

Publication Number Publication Date
PL1668001T3 true PL1668001T3 (pl) 2009-04-30

Family

ID=34396284

Family Applications (1)

Application Number Title Priority Date Filing Date
PL04784968T PL1668001T3 (pl) 2003-09-25 2004-09-24 Podstawione heteroarylobenzofuranowe kwasy

Country Status (13)

Country Link
US (2) US7446201B2 (pl)
EP (1) EP1668001B1 (pl)
JP (1) JP2007506760A (pl)
AT (1) ATE412649T1 (pl)
AU (1) AU2004276305A1 (pl)
BR (1) BRPI0414463A (pl)
CA (1) CA2538711A1 (pl)
DE (1) DE602004017486D1 (pl)
DK (1) DK1668001T3 (pl)
ES (1) ES2315711T3 (pl)
MX (1) MXPA06003249A (pl)
PL (1) PL1668001T3 (pl)
WO (1) WO2005030760A1 (pl)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI224101B (en) * 2001-06-20 2004-11-21 Wyeth Corp Substituted naphthyl indole derivatives as inhibitors of plasminogen activator inhibitor type-1 (PAI-1)
DK1397130T3 (da) * 2001-06-20 2007-11-12 Wyeth Corp Substituerede indolsyrederivater som inhibitorer af plasminogenaktivatorinhibitor-1 (PAI-1)
WO2004052854A2 (en) * 2002-12-10 2004-06-24 Wyeth Aryl, aryloxy, and alkyloxy substituted 1h-indol-3-yl glyoxylic acid derivatives as inhibitors of plasminogen activator inhibitor-1 (pai-1)
CA2509170A1 (en) * 2002-12-10 2004-06-24 Wyeth Substituted 3-alkyl and 3-arylalkyl 1h-indol-1-yl acetic acid derivatives as inhibitors of plasminogen activator inhibitor-1 (pai-1)
DK1569900T3 (da) * 2002-12-10 2006-10-23 Wyeth Corp Substituerede 3-carbonyl-1-yl-eddikesyrederivater som inhibitorer af plasminogenaktivator-inhibitor-1 (PAI-1)
UA80453C2 (en) * 2002-12-10 2007-09-25 Derivatives of substituted dyhydropyranoindol-3,4-dion as inhibitors of plasminogen activator inhibitor-1 (pai-1)
US7420083B2 (en) 2003-09-25 2008-09-02 Wyeth Substituted aryloximes
US7534894B2 (en) * 2003-09-25 2009-05-19 Wyeth Biphenyloxy-acids
US7332521B2 (en) * 2003-09-25 2008-02-19 Wyeth Substituted indoles
US7342039B2 (en) * 2003-09-25 2008-03-11 Wyeth Substituted indole oximes
US7163954B2 (en) * 2003-09-25 2007-01-16 Wyeth Substituted naphthyl benzothiophene acids
US7268159B2 (en) * 2003-09-25 2007-09-11 Wyeth Substituted indoles
US7351726B2 (en) 2003-09-25 2008-04-01 Wyeth Substituted oxadiazolidinediones
US7582773B2 (en) * 2003-09-25 2009-09-01 Wyeth Substituted phenyl indoles
US7411083B2 (en) 2003-09-25 2008-08-12 Wyeth Substituted acetic acid derivatives
US7446201B2 (en) * 2003-09-25 2008-11-04 Wyeth Substituted heteroaryl benzofuran acids
US7265148B2 (en) * 2003-09-25 2007-09-04 Wyeth Substituted pyrrole-indoles
US7442805B2 (en) * 2003-09-25 2008-10-28 Wyeth Substituted sulfonamide-indoles
US7141592B2 (en) * 2003-09-25 2006-11-28 Wyeth Substituted oxadiazolidinediones
AU2005277137A1 (en) * 2004-08-23 2006-03-02 Wyeth Pyrrolo-naphthyl acids as PAI-1 inhibitors
AU2005277138A1 (en) * 2004-08-23 2006-03-02 Wyeth Holdings Corporation Oxazolo-naphthyl acids as plaminogen activator inhibtor type-1 (PAI-1) modulators useful in the treatment of thrombosis and cardiovascular diseases
AU2005277139A1 (en) * 2004-08-23 2006-03-02 Wyeth Thiazolo-naphthyl acids as inhibitors of plasminogen activator inhibitor-1
BRPI0614340A2 (pt) * 2005-08-17 2011-04-12 Wyeth Corp indóis substituìdos e métodos de seu uso
WO2007098278A2 (en) * 2006-02-27 2007-08-30 Wyeth Inhibitors of pai-1 for treatment of muscular conditions
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CN105294662B (zh) * 2015-09-11 2018-04-20 中山大学 苯并呋喃喹啉衍生物及其在制备治疗阿尔茨海默病症的药品中的应用

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Also Published As

Publication number Publication date
CA2538711A1 (en) 2005-04-07
US20090054484A1 (en) 2009-02-26
AU2004276305A1 (en) 2005-04-07
JP2007506760A (ja) 2007-03-22
EP1668001B1 (en) 2008-10-29
ATE412649T1 (de) 2008-11-15
WO2005030760A1 (en) 2005-04-07
DE602004017486D1 (de) 2008-12-11
ES2315711T3 (es) 2009-04-01
DK1668001T3 (da) 2009-02-16
US7446201B2 (en) 2008-11-04
MXPA06003249A (es) 2006-06-08
EP1668001A1 (en) 2006-06-14
US20050119296A1 (en) 2005-06-02
BRPI0414463A (pt) 2006-11-14

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