BRPI0409716A - derivados de 2-acilamino-4-feniltiazol, seu preparo e sua aplicação em terapêutica - Google Patents
derivados de 2-acilamino-4-feniltiazol, seu preparo e sua aplicação em terapêuticaInfo
- Publication number
- BRPI0409716A BRPI0409716A BRPI0409716-5A BRPI0409716A BRPI0409716A BR PI0409716 A BRPI0409716 A BR PI0409716A BR PI0409716 A BRPI0409716 A BR PI0409716A BR PI0409716 A BRPI0409716 A BR PI0409716A
- Authority
- BR
- Brazil
- Prior art keywords
- acylamino
- application
- preparation
- therapeutic
- derivatives
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/44—Acylated amino or imino radicals
- C07D277/46—Acylated amino or imino radicals by carboxylic acids, or sulfur or nitrogen analogues thereof
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/10—Spiro-condensed systems
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Virology (AREA)
- Diabetes (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Obesity (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Dermatology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Neurology (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Hospice & Palliative Care (AREA)
- Emergency Medicine (AREA)
- Biotechnology (AREA)
- Child & Adolescent Psychology (AREA)
- Psychiatry (AREA)
Abstract
"DERIVADOS DE 2-ACILAMINO-4-FENILTIAZOL, SEU PREPARO E SUA APLICAçãO EM TERAPêUTICA". Derivados de 2-acilamino-4-feniltiazol, seu preparo e sua aplicação em terapêutica. A invenção se refere aos derivados de 2 -acilamino-4-feniltiazol de fórmula geral (I). Processo de preparo e sua aplicação em terapêutica.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0305213A FR2854158B1 (fr) | 2003-04-25 | 2003-04-25 | Derives de 2-acylamino-4-phenylethiazole, leur preparation et leur application en therapeutique |
PCT/FR2004/000981 WO2004096798A2 (fr) | 2003-04-25 | 2004-04-22 | Derives de 2-acylamino-4-phenylthiazole, leur preparation et leur application en therapeutique |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0409716A true BRPI0409716A (pt) | 2006-05-02 |
Family
ID=33104460
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0409716-5A BRPI0409716A (pt) | 2003-04-25 | 2004-04-22 | derivados de 2-acilamino-4-feniltiazol, seu preparo e sua aplicação em terapêutica |
Country Status (24)
Country | Link |
---|---|
US (2) | US7504511B2 (pt) |
EP (1) | EP1656373B1 (pt) |
JP (2) | JP4839208B2 (pt) |
KR (1) | KR20060006935A (pt) |
CN (1) | CN1826339A (pt) |
AR (1) | AR044070A1 (pt) |
AT (1) | ATE541843T1 (pt) |
AU (1) | AU2004234101A1 (pt) |
BR (1) | BRPI0409716A (pt) |
CA (1) | CA2521158A1 (pt) |
CO (1) | CO5640106A2 (pt) |
CR (1) | CR8037A (pt) |
EC (1) | ECSP056111A (pt) |
FR (1) | FR2854158B1 (pt) |
MA (1) | MA27769A1 (pt) |
MX (1) | MXPA05011522A (pt) |
NO (1) | NO20054905L (pt) |
OA (1) | OA13049A (pt) |
RS (1) | RS20050769A (pt) |
RU (1) | RU2348630C2 (pt) |
TN (1) | TNSN05254A1 (pt) |
TW (1) | TW200510325A (pt) |
WO (1) | WO2004096798A2 (pt) |
ZA (1) | ZA200508608B (pt) |
Families Citing this family (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JO2527B1 (en) * | 2004-04-06 | 2010-03-17 | شركة جانسين فارماسوتيكا ان. في | Derivatives of second-aza-Spiro- (5,5) -andecan and their use as antihistamines |
JO2676B1 (en) * | 2004-04-06 | 2012-06-17 | جانسين فارماسوتيكا ان. في | Derivatives of second-aza-spiro- (5,4) -dikan and their use as antihistamines |
FR2872813B1 (fr) | 2004-07-09 | 2007-01-19 | Sanofi Synthelabo | Derives de 2-carbamide-4-phenylthiazole, leur preparation et leur application en therapeutique |
GB0421908D0 (en) * | 2004-10-01 | 2004-11-03 | Angeletti P Ist Richerche Bio | New uses |
FR2876692B1 (fr) * | 2004-10-19 | 2007-02-23 | Sanofi Aventis Sa | Derives de 2-amido-4-phenylthiazole, leur preparation et leur application en therapeutique |
US20060160869A1 (en) * | 2005-01-05 | 2006-07-20 | Rigel Pharmaceuticals, Inc. | Ubiquitin ligase inhibitors |
JP5078869B2 (ja) | 2005-03-08 | 2012-11-21 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | ニューロキニン(nk1)拮抗物質としてのジアザ−スピロ−[4.4]−ノナン誘導体 |
AU2006244203B2 (en) * | 2005-05-09 | 2012-05-03 | Achillion Pharmaceuticals, Inc. | Thiazole compounds and methods of use |
WO2007053498A1 (en) * | 2005-11-01 | 2007-05-10 | Millennium Pharmaceuticals, Inc. | Compounds useful as antagonists of ccr2 |
WO2007053495A2 (en) * | 2005-11-01 | 2007-05-10 | Millennium Pharmaceuticals, Inc. | Compounds useful as antagonists of ccr2 |
US8067415B2 (en) | 2005-11-01 | 2011-11-29 | Millennium Pharmaceuticals, Inc. | Compounds useful as antagonists of CCR2 |
FR2895989B1 (fr) * | 2006-01-06 | 2010-04-30 | Sanofi Aventis | Derives de 2-carbamide-4-phenylthiazole, leur preparation et leur application en therapeutique |
EP2059515A2 (en) * | 2006-04-12 | 2009-05-20 | Pfizer Limited | Pyrrolidine derivatives as modulators of chemokine ccr5 receptors |
CN101096363B (zh) | 2006-06-27 | 2011-05-11 | 中国人民解放军军事医学科学院毒物药物研究所 | 2,4,5-三取代噻唑类化合物、其制备方法、药物组合物及其制药用途 |
US20080076120A1 (en) * | 2006-09-14 | 2008-03-27 | Millennium Pharmaceuticals, Inc. | Methods for the identification, evaluation and treatment of patients having CC-Chemokine receptor 2 (CCR-2) mediated disorders |
MX2009005252A (es) * | 2006-11-17 | 2009-05-28 | Abbott Lab | Aminopirrolidinas como antagonistas del receptor de quimiocina. |
AU2008214679A1 (en) * | 2007-02-13 | 2008-08-21 | Ab Science | Process for the synthesis of 2-aminothiazole compounds as kinase inhibitors |
WO2008124000A2 (en) * | 2007-04-02 | 2008-10-16 | Ligand Pharmaceuticals Incorporated | Thiazole derivatives as androgen receptor modulator compounds |
CA2687931C (en) | 2007-05-31 | 2016-05-24 | Boehringer Ingelheim International Gmbh | Ccr2 receptor antagonists and uses thereof |
MX2010001082A (es) * | 2007-07-31 | 2010-03-01 | Shionogi & Co | Composicion farmaceutica que contiene compuesto opticamente activo que tiene actividad agonista del receptor de trombopoyetina y compuesto intermedio para el mismo. |
EP2379525B1 (en) | 2008-12-19 | 2015-07-29 | Boehringer Ingelheim International GmbH | Cyclic pyrimidin-4-carboxamides as ccr2 receptor antagonists for treatment of inflammation, asthma and copd |
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FR2876692B1 (fr) | 2004-10-19 | 2007-02-23 | Sanofi Aventis Sa | Derives de 2-amido-4-phenylthiazole, leur preparation et leur application en therapeutique |
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2003
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- 2004-04-22 AT AT04742558T patent/ATE541843T1/de active
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- 2004-04-22 EP EP04742558A patent/EP1656373B1/fr not_active Expired - Lifetime
- 2004-04-22 KR KR1020057020168A patent/KR20060006935A/ko not_active Application Discontinuation
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- 2004-04-22 WO PCT/FR2004/000981 patent/WO2004096798A2/fr active Search and Examination
- 2004-04-22 AU AU2004234101A patent/AU2004234101A1/en not_active Abandoned
- 2004-04-22 OA OA1200500305A patent/OA13049A/fr unknown
- 2004-04-22 CN CNA2004800180511A patent/CN1826339A/zh active Pending
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2005
- 2005-10-06 TN TNP2005000254A patent/TNSN05254A1/en unknown
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JP2011126891A (ja) | 2011-06-30 |
NO20054905L (no) | 2006-01-25 |
MXPA05011522A (es) | 2006-01-23 |
WO2004096798A3 (fr) | 2006-01-26 |
TNSN05254A1 (en) | 2007-07-10 |
AU2004234101A1 (en) | 2004-11-11 |
KR20060006935A (ko) | 2006-01-20 |
CA2521158A1 (fr) | 2004-11-11 |
OA13049A (fr) | 2006-11-10 |
RS20050769A (en) | 2007-11-15 |
FR2854158B1 (fr) | 2006-11-17 |
RU2348630C2 (ru) | 2009-03-10 |
ECSP056111A (es) | 2006-03-01 |
CO5640106A2 (es) | 2006-05-31 |
CR8037A (es) | 2008-07-29 |
US7777041B2 (en) | 2010-08-17 |
FR2854158A1 (fr) | 2004-10-29 |
US20060135575A1 (en) | 2006-06-22 |
EP1656373A2 (fr) | 2006-05-17 |
TW200510325A (en) | 2005-03-16 |
WO2004096798A2 (fr) | 2004-11-11 |
JP2006524669A (ja) | 2006-11-02 |
ATE541843T1 (de) | 2012-02-15 |
US20090156574A1 (en) | 2009-06-18 |
US7504511B2 (en) | 2009-03-17 |
ZA200508608B (en) | 2007-01-31 |
MA27769A1 (fr) | 2006-02-01 |
RU2005136663A (ru) | 2006-03-20 |
CN1826339A (zh) | 2006-08-30 |
NO20054905D0 (no) | 2005-10-24 |
EP1656373B1 (fr) | 2012-01-18 |
JP4839208B2 (ja) | 2011-12-21 |
AR044070A1 (es) | 2005-08-24 |
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