FR2827861B1 - Derives des indazoles ou des indoles, leur utilisation en medecine humaine et plus particulierement en cancerologie - Google Patents

Derives des indazoles ou des indoles, leur utilisation en medecine humaine et plus particulierement en cancerologie

Info

Publication number
FR2827861B1
FR2827861B1 FR0110118A FR0110118A FR2827861B1 FR 2827861 B1 FR2827861 B1 FR 2827861B1 FR 0110118 A FR0110118 A FR 0110118A FR 0110118 A FR0110118 A FR 0110118A FR 2827861 B1 FR2827861 B1 FR 2827861B1
Authority
FR
France
Prior art keywords
cancerology
indazoles
indoles
derivatives
human medicine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0110118A
Other languages
English (en)
Other versions
FR2827861A1 (fr
Inventor
Conception Nemecek
Patrick Mailliet
Fabienne Thompson
Michel Tabart
Eric Bacque
Sylvie Wentzler
Cecile Combeau
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharma SA
Original Assignee
Aventis Pharma SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma SA filed Critical Aventis Pharma SA
Priority to FR0110118A priority Critical patent/FR2827861B1/fr
Priority to EP02791508A priority patent/EP1414805A1/fr
Priority to JP2003517025A priority patent/JP2005503376A/ja
Priority to PCT/FR2002/002638 priority patent/WO2003011833A1/fr
Priority to ARP020102840A priority patent/AR036348A1/es
Publication of FR2827861A1 publication Critical patent/FR2827861A1/fr
Priority to US10/761,982 priority patent/US7119115B2/en
Application granted granted Critical
Publication of FR2827861B1 publication Critical patent/FR2827861B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
    • C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32—Oxygen atoms
    • C07D209/36—Oxygen atoms in position 3, e.g. adrenochrome
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
FR0110118A 2001-07-27 2001-07-27 Derives des indazoles ou des indoles, leur utilisation en medecine humaine et plus particulierement en cancerologie Expired - Fee Related FR2827861B1 (fr)

Priority Applications (6)

Application Number Priority Date Filing Date Title
FR0110118A FR2827861B1 (fr) 2001-07-27 2001-07-27 Derives des indazoles ou des indoles, leur utilisation en medecine humaine et plus particulierement en cancerologie
EP02791508A EP1414805A1 (fr) 2001-07-27 2002-07-24 Derives des indazoles ou des indoles, leur utilisation en medecine humaine et plus particulierement en cancerologie
JP2003517025A JP2005503376A (ja) 2001-07-27 2002-07-24 インダゾールまたはインドール誘導体およびヒトの医療、より詳しくは癌の治療におけるそれらの使用
PCT/FR2002/002638 WO2003011833A1 (fr) 2001-07-27 2002-07-24 Derives des indazoles ou des indoles, leur utilisation en medecine humaine et plus particulierement en cancerologie
ARP020102840A AR036348A1 (es) 2001-07-27 2002-07-26 Derivados de indazoles o de indoles, utiles en medicina humana y mas particularmente en cancerologia.
US10/761,982 US7119115B2 (en) 2001-07-27 2004-01-21 Indazole or indole derivatives, and use thereof in human medicine and more particularly in oncology

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0110118A FR2827861B1 (fr) 2001-07-27 2001-07-27 Derives des indazoles ou des indoles, leur utilisation en medecine humaine et plus particulierement en cancerologie

Publications (2)

Publication Number Publication Date
FR2827861A1 FR2827861A1 (fr) 2003-01-31
FR2827861B1 true FR2827861B1 (fr) 2004-04-02

Family

ID=8866025

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0110118A Expired - Fee Related FR2827861B1 (fr) 2001-07-27 2001-07-27 Derives des indazoles ou des indoles, leur utilisation en medecine humaine et plus particulierement en cancerologie

Country Status (6)

Country Link
US (1) US7119115B2 (fr)
EP (1) EP1414805A1 (fr)
JP (1) JP2005503376A (fr)
AR (1) AR036348A1 (fr)
FR (1) FR2827861B1 (fr)
WO (1) WO2003011833A1 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7196082B2 (en) 2002-11-08 2007-03-27 Merck & Co. Inc. Ophthalmic compositions for treating ocular hypertension
AR045037A1 (es) * 2003-07-10 2005-10-12 Aventis Pharma Sa Tetrahidro-1h-pirazolo [3,4-c] piridinas sustituidas, composiciones que las contienen y su utilizacion.
FR2857362B1 (fr) * 2003-07-10 2005-09-23 Aventis Pharma Sa Tetrahydro-1h-pyrazolo[3,4-c] pyridines substituees, compositions les contenant et utilisation
FR2871158A1 (fr) * 2004-06-04 2005-12-09 Aventis Pharma Sa Indazoles substitues, compositions les contenant, procede de fabrication et utilisation
CA2862276A1 (fr) * 2012-01-25 2013-08-01 Kabushiki Kaisha Yakult Honsha Compose pyrrole
CN102924377A (zh) * 2012-10-22 2013-02-13 华东师范大学 3,4,5-取代吡唑类化合物的合成方法
WO2020102616A1 (fr) * 2018-11-16 2020-05-22 Nimbus Artemis, Inc. Inhibiteurs d'acyle et leurs utilisations

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
YU54202A (sh) * 2000-01-18 2006-01-16 Agouron Pharmaceuticals Inc. Jedinjenja indazola, farmaceutske smeše i postupci za stimulisanje i inhibiranje ćelijske proliferacije

Also Published As

Publication number Publication date
JP2005503376A (ja) 2005-02-03
WO2003011833A1 (fr) 2003-02-13
FR2827861A1 (fr) 2003-01-31
US20040162276A1 (en) 2004-08-19
AR036348A1 (es) 2004-09-01
US7119115B2 (en) 2006-10-10
EP1414805A1 (fr) 2004-05-06

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Date Code Title Description
ST Notification of lapse

Effective date: 20080331