PL1742659T3 - Poddane mikrofluidyzacji emulsje typu olej w wodzie oraz kompozycje szczepionek - Google Patents
Poddane mikrofluidyzacji emulsje typu olej w wodzie oraz kompozycje szczepionekInfo
- Publication number
- PL1742659T3 PL1742659T3 PL05718292T PL05718292T PL1742659T3 PL 1742659 T3 PL1742659 T3 PL 1742659T3 PL 05718292 T PL05718292 T PL 05718292T PL 05718292 T PL05718292 T PL 05718292T PL 1742659 T3 PL1742659 T3 PL 1742659T3
- Authority
- PL
- Poland
- Prior art keywords
- water emulsions
- vaccine compositions
- microfluidized oil
- microfluidized
- oil
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/0225—Spirochetes, e.g. Treponema, Leptospira, Borrelia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/025—Enterobacteriales, e.g. Enterobacter
- A61K39/0258—Escherichia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
- A61K39/092—Streptococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/155—Paramyxoviridae, e.g. parainfluenza virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/521—Bacterial cells; Fungal cells; Protozoal cells inactivated (killed)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
- A61K2039/552—Veterinary vaccine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55577—Saponins; Quil A; QS21; ISCOMS
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/70—Multivalent vaccine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24311—Pestivirus, e.g. bovine viral diarrhea virus
- C12N2770/24334—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US55967704P | 2004-04-05 | 2004-04-05 | |
PCT/IB2005/000804 WO2005097181A1 (en) | 2004-04-05 | 2005-03-24 | Microfluidized oil-in-water emulsions and vaccine compositions |
EP20050718292 EP1742659B1 (en) | 2004-04-05 | 2005-03-24 | Microfluidized oil-in-water emulsions and vaccine compositions |
Publications (1)
Publication Number | Publication Date |
---|---|
PL1742659T3 true PL1742659T3 (pl) | 2013-08-30 |
Family
ID=34961993
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL05718292T PL1742659T3 (pl) | 2004-04-05 | 2005-03-24 | Poddane mikrofluidyzacji emulsje typu olej w wodzie oraz kompozycje szczepionek |
Country Status (23)
Country | Link |
---|---|
US (1) | US7122191B2 (pl) |
EP (2) | EP2269644A3 (pl) |
JP (2) | JP5393978B2 (pl) |
KR (5) | KR20070008625A (pl) |
CN (1) | CN1997390B (pl) |
AR (1) | AR048822A1 (pl) |
AU (1) | AU2005230708B2 (pl) |
BR (1) | BRPI0509606B1 (pl) |
CA (1) | CA2561914C (pl) |
DK (1) | DK1742659T3 (pl) |
ES (1) | ES2409782T3 (pl) |
HK (1) | HK1108830A1 (pl) |
NO (1) | NO341034B1 (pl) |
NZ (1) | NZ550152A (pl) |
PL (1) | PL1742659T3 (pl) |
PT (1) | PT1742659E (pl) |
RU (1) | RU2347586C2 (pl) |
SI (1) | SI1742659T1 (pl) |
TW (1) | TWI301067B (pl) |
UA (1) | UA89631C2 (pl) |
UY (1) | UY28840A1 (pl) |
WO (1) | WO2005097181A1 (pl) |
ZA (1) | ZA200608200B (pl) |
Families Citing this family (122)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
USRE39494E1 (en) * | 1992-02-27 | 2007-02-27 | Intervet Inc. | Inactivated mycoplasma hyopneumoniae and uses therefor |
ATE317267T1 (de) | 2000-11-07 | 2006-02-15 | Immunovaccine Technologies Inc | Impfstoffe mit erhöhter immunantwort und verfahren zur deren herstellung |
AR044732A1 (es) * | 2002-11-08 | 2005-10-05 | H P B S A | Composicion farmaceutica para el tratamiento medico de la hiperplasia benigan de la prostata, su metodo de preparacion y su aplicacion terapeutica |
KR20070008625A (ko) * | 2004-04-05 | 2007-01-17 | 화이자 프로덕츠 인코포레이티드 | 미세유체화된 수중유 유화액 및 백신 조성물 |
PE20110072A1 (es) * | 2005-06-27 | 2011-02-04 | Glaxosmithkline Biolog Sa | Composicion inmunogenica |
EP1945250A4 (en) * | 2005-08-16 | 2010-05-19 | Hawaii Biotech Inc | RECOMBINANT SUBUNIT VACCINE FOR INFLUENZA VIRUS |
AU2006310163B2 (en) | 2005-11-04 | 2011-09-15 | Seqirus UK Limited | Influenza vaccine with reduced amount of oil-in-water emulsion as adjuvant |
PT2368572T (pt) | 2005-11-04 | 2020-06-16 | Seqirus Uk Ltd | Vacinas com adjuvante dotadas de antigénios não-virião preparados a partir de vírus da gripe cultivado em cultura celular |
NZ568210A (en) | 2005-11-04 | 2012-12-21 | Novartis Vaccines & Diagnostic | Emulsions with free aqueous-phase surfactant as adjuvants for split influenza vaccines |
EP2377551A3 (en) | 2005-11-04 | 2013-04-24 | Novartis Vaccines and Diagnostics S.r.l. | Adjuvanted influenza vaccines including cytokine-inducing agents |
EP1792619A1 (en) * | 2005-11-28 | 2007-06-06 | Laboratorios Maymo, S.A. | Beta-sitosterol for treating porcine respiratory disease complex |
ES2619160T7 (es) | 2006-01-27 | 2020-07-29 | Seqirus Uk Ltd | Vacunas contra la gripe que contienen hemaglutinina y proteínas de la matriz |
WO2007098186A2 (en) * | 2006-02-22 | 2007-08-30 | Novavax, Inc. | Adjuvant and vaccine compositions |
JP2009534303A (ja) | 2006-03-24 | 2009-09-24 | ノバルティス ヴァクシンズ アンド ダイアグノスティクス ゲーエムベーハー アンド カンパニー カーゲー | 冷蔵しないインフルエンザワクチンの保存 |
SG173336A1 (en) | 2006-03-31 | 2011-08-29 | Novartis Ag | Combined mucosal and parenteral immunization against hiv |
DK2054431T3 (da) | 2006-06-09 | 2012-01-02 | Novartis Ag | Konformere af bakterielle adhæsiner |
CA3016948A1 (en) | 2006-09-11 | 2008-03-20 | Seqirus UK Limited | Making influenza virus vaccines without using eggs |
EA200900784A1 (ru) | 2006-12-06 | 2009-12-30 | Новартис Аг | Вакцины, включающие антиген из четырех штаммов вируса гриппа |
GB0700562D0 (en) | 2007-01-11 | 2007-02-21 | Novartis Vaccines & Diagnostic | Modified Saccharides |
US8877206B2 (en) | 2007-03-22 | 2014-11-04 | Pds Biotechnology Corporation | Stimulation of an immune response by cationic lipids |
PL2185191T3 (pl) | 2007-06-27 | 2013-02-28 | Novartis Ag | Szczepionki przeciwko grypie o małej zawartości dodatków |
GB0714963D0 (en) | 2007-08-01 | 2007-09-12 | Novartis Ag | Compositions comprising antigens |
CN101827613A (zh) | 2007-09-27 | 2010-09-08 | 免疫疫苗技术有限公司 | 在包括连续疏水相的载体中的脂质体在体内输送多核苷酸中的应用 |
PL2200642T3 (pl) | 2007-10-19 | 2012-09-28 | Novartis Ag | Preparaty szczepionek meningokokowych |
GB0810305D0 (en) | 2008-06-05 | 2008-07-09 | Novartis Ag | Influenza vaccination |
GB0818453D0 (en) | 2008-10-08 | 2008-11-12 | Novartis Ag | Fermentation processes for cultivating streptococci and purification processes for obtaining cps therefrom |
EP2889042A3 (en) | 2008-03-18 | 2015-10-14 | Novartis AG | Improvements in preparation of influenza virus vaccine antigens |
US9789129B2 (en) | 2008-04-17 | 2017-10-17 | Pds Biotechnology Corporation | Stimulation of an immune response by enantiomers of cationic lipids |
TWI551295B (zh) * | 2008-04-18 | 2016-10-01 | 英特威特國際股份有限公司 | 防備胞內勞森菌(Lawsonia intracellularis)用疫苗 |
EP2296696B1 (en) | 2008-06-05 | 2014-08-27 | ImmunoVaccine Technologies Inc. | Compositions comprising liposomes, an antigen, a polynucleotide and a carrier comprising a continuous phase of a hydrophobic substance |
AU2012258478B2 (en) * | 2008-06-27 | 2013-10-03 | Zoetis Services Llc | Novel adjuvant compositions |
CN104001170B (zh) * | 2008-06-27 | 2016-08-24 | 硕腾有限责任公司 | 新颖的佐剂组合物 |
EP2331127A2 (en) | 2008-09-18 | 2011-06-15 | Novartis AG | Vaccine adjuvant combinations |
CN102438651A (zh) | 2009-02-10 | 2012-05-02 | 诺华有限公司 | 用于大流行相关毒株的流感疫苗方案 |
AU2010212548A1 (en) | 2009-02-10 | 2011-09-15 | Novartis Ag | Influenza vaccines with increased amounts of H3 antigen |
EP2396032B1 (en) | 2009-02-10 | 2016-09-28 | Seqirus UK Limited | Influenza vaccines with reduced amounts of squalene |
EP3549602A1 (en) | 2009-03-06 | 2019-10-09 | GlaxoSmithKline Biologicals S.A. | Chlamydia antigens |
WO2010109324A1 (en) | 2009-03-24 | 2010-09-30 | Novartis Ag | Combinations of meningococcal factor h binding protein and pneumococcal saccharide conjugates |
EP2510947B1 (en) | 2009-04-14 | 2016-02-10 | GlaxoSmithKline Biologicals SA | Compositions for immunising against Staphylococcus aureus |
EP2573184A1 (en) | 2009-05-21 | 2013-03-27 | Novartis AG | Reverse genetics using non-endogenous POL I promoters |
CN103764160A (zh) | 2009-05-29 | 2014-04-30 | 诺华有限公司 | 流感病毒血凝素试验 |
JP2012532600A (ja) | 2009-07-07 | 2012-12-20 | ノバルティス アーゲー | 保存された大腸菌免疫原 |
CN105214080A (zh) | 2009-07-15 | 2016-01-06 | 诺华股份有限公司 | Rsv f蛋白组合物和其制作方法 |
PL2464658T3 (pl) | 2009-07-16 | 2015-03-31 | Novartis Ag | Immunogeny z Escherichia coli o zniesionej toksyczności |
JP2013500712A (ja) | 2009-07-31 | 2013-01-10 | ノバルティス アーゲー | 逆遺伝学系 |
CN107582526A (zh) * | 2009-08-12 | 2018-01-16 | 希格默伊德药业有限公司 | 包含聚合物基质和油相的免疫调节组合物 |
EP2475385A1 (en) | 2009-09-10 | 2012-07-18 | Novartis AG | Combination vaccines against respiratory tract diseases |
GB0917002D0 (en) | 2009-09-28 | 2009-11-11 | Novartis Vaccines Inst For Global Health Srl | Improved shigella blebs |
GB0917003D0 (en) | 2009-09-28 | 2009-11-11 | Novartis Vaccines Inst For Global Health Srl | Purification of bacterial vesicles |
US20130022639A1 (en) | 2009-09-30 | 2013-01-24 | Novartis Ag | Expression of meningococcal fhbp polypeptides |
AU2010309404B2 (en) | 2009-10-20 | 2015-07-09 | Seqirus UK Limited | Improved reverse genetics methods for virus rescue |
GB0918392D0 (en) | 2009-10-20 | 2009-12-02 | Novartis Ag | Diagnostic and therapeutic methods |
US20120219605A1 (en) * | 2009-11-05 | 2012-08-30 | Peter Blackburn | Adjuvanted nanoparticulate influenza vaccine |
GB0919690D0 (en) | 2009-11-10 | 2009-12-23 | Guy S And St Thomas S Nhs Foun | compositions for immunising against staphylococcus aureus |
CL2012001399A1 (es) | 2009-12-03 | 2013-03-08 | Novartis Ag | Metodo para fabricar adyuvante para vacuna (emulsion aceite/agua con escualeno, polisorbato 80 y trioleato de sorbitan), que comprende (i) formar primera emulsion en homogenizador desde un contendor a otro para formar segunda emulsion, (ii) y microfluidizar primera emulsion para formar segunda emulsion. |
EP2638895B1 (en) * | 2009-12-03 | 2024-03-20 | Seqirus UK Limited | Circulation of components during homogenization of emulsions |
DE102009056883B4 (de) * | 2009-12-03 | 2012-08-16 | Novartis Ag | Impfstoff-Adjuvantien und verbesserte Verfahren zur Herstellung derselben |
DE102009056871A1 (de) * | 2009-12-03 | 2011-06-22 | Novartis AG, 4056 | Impfstoff-Adjuvantien und verbesserte Verfahren zur Herstellung derselben |
DE102009056884B4 (de) | 2009-12-03 | 2021-03-18 | Novartis Ag | Impfstoff-Adjuvantien und verbesserte Verfahren zur Herstellung derselben |
EP2601933B1 (en) | 2009-12-03 | 2015-10-07 | Novartis AG | Hydrophilic filtration during manufacture of vaccine adjuvants |
JP5781542B2 (ja) | 2009-12-30 | 2015-09-24 | ノバルティス アーゲー | E.coliキャリアタンパク質に結合体化した多糖免疫原 |
GB201003333D0 (en) | 2010-02-26 | 2010-04-14 | Novartis Ag | Immunogenic proteins and compositions |
CN102802662A (zh) | 2010-03-18 | 2012-11-28 | 诺华有限公司 | 用于脑膜炎球菌血清组b的含佐剂疫苗 |
GB201005625D0 (en) | 2010-04-01 | 2010-05-19 | Novartis Ag | Immunogenic proteins and compositions |
AU2011254204B2 (en) | 2010-05-21 | 2015-08-20 | Seqirus UK Limited | Influenza virus reassortment method |
GB201009861D0 (en) | 2010-06-11 | 2010-07-21 | Novartis Ag | OMV vaccines |
EP2585106A1 (en) | 2010-06-25 | 2013-05-01 | Novartis AG | Combinations of meningococcal factor h binding proteins |
CN101926994B (zh) * | 2010-08-19 | 2012-10-10 | 中国医学科学院医学生物学研究所 | 一种鳖甲免疫佐剂及含有该佐剂的流感疫苗 |
GB201017519D0 (en) | 2010-10-15 | 2010-12-01 | Novartis Vaccines Inst For Global Health S R L | Vaccines |
WO2012072769A1 (en) | 2010-12-01 | 2012-06-07 | Novartis Ag | Pneumococcal rrgb epitopes and clade combinations |
EP2667892B1 (en) | 2011-01-26 | 2019-03-27 | GlaxoSmithKline Biologicals SA | Rsv immunization regimen |
CN103533954B (zh) | 2011-03-02 | 2015-09-09 | 诺华股份有限公司 | 含较低剂量的抗原和/或佐剂的联合疫苗 |
PT3275892T (pt) | 2011-05-13 | 2020-04-08 | Glaxosmithkline Biologicals Sa | Antigénios f de rsv de pré-fusão |
WO2013009564A1 (en) | 2011-07-08 | 2013-01-17 | Novartis Ag | Tyrosine ligation process |
EP2755683B1 (en) | 2011-09-14 | 2019-04-03 | GlaxoSmithKline Biologicals SA | Methods for making saccharide-protein glycoconjugates |
ES2855474T3 (es) | 2011-10-06 | 2021-09-23 | Immunovaccine Technologies Inc | Composiciones de liposomas que comprenden un adyuvante que activa o incrementa la actividad de TLR2 y usos del mismo |
WO2013057715A1 (en) | 2011-10-20 | 2013-04-25 | Novartis Ag | Adjuvanted influenza b virus vaccines for pediatric priming |
CA2854934A1 (en) | 2011-11-07 | 2013-05-16 | Novartis Ag | Carrier molecule comprising a spr0096 and a spr2021 antigen |
JP2016539314A (ja) | 2011-12-12 | 2016-12-15 | ノバルティス アーゲー | インフルエンザウイルス血球凝集素のためのアッセイ法 |
WO2013092985A1 (en) | 2011-12-23 | 2013-06-27 | Novartis Ag | Stable compositions for immunising against staphylococcus aureus |
CN103608453B (zh) | 2012-03-02 | 2018-07-24 | 思齐乐 | 流感病毒重配 |
RU2014140521A (ru) | 2012-03-08 | 2016-04-27 | Новартис Аг | Адъювантные составы бустерных вакцин |
WO2013182498A1 (en) | 2012-06-04 | 2013-12-12 | Novartis Ag | Improved safety testing |
JP6435261B2 (ja) | 2012-08-31 | 2018-12-05 | ノバルティス アーゲー | Staphylococcusaureusに対する免疫化のための安定化されたタンパク質 |
EP2890395A1 (en) | 2012-08-31 | 2015-07-08 | Novartis AG | Stabilised proteins for immunising against staphylococcus aureus |
EP2892553A1 (en) | 2012-09-06 | 2015-07-15 | Novartis AG | Combination vaccines with serogroup b meningococcus and d/t/p |
AU2013320313B2 (en) | 2012-09-18 | 2018-07-12 | Glaxosmithkline Biologicals Sa | Outer membrane vesicles |
AU2013317805B2 (en) | 2012-09-21 | 2018-07-26 | Pds Biotechnology Corporation | Improved vaccine compositions and methods of use |
EA201590427A1 (ru) | 2012-10-02 | 2015-09-30 | Глаксосмитклайн Байолоджикалс С.А. | Нелинейные сахаридные конъюгаты |
ES2717441T3 (es) | 2012-10-09 | 2019-06-21 | Univ Gent | Vacuna contra Cooperia |
GB201218195D0 (en) | 2012-10-10 | 2012-11-21 | Istituto Zooprofilattico Sperimentale Delle Venezie | Composition |
RU2015111987A (ru) | 2012-10-12 | 2016-12-10 | Глаксосмитклайн Байолоджикалс Са | Несшитые бесклеточные коклюшные антигены для применения в комбинированных вакцинах |
DK2925355T3 (en) | 2012-11-30 | 2018-01-15 | Glaxosmithkline Biologicals Sa | PSEUDOMONAS ANTIGENES AND ANTIGEN COMBINATIONS |
MX2015006927A (es) | 2012-12-03 | 2016-02-05 | Novartis Ag | Redistribucion de virus de la influenza. |
UY34506A (es) | 2012-12-10 | 2014-06-30 | Fernando Amaury Ferreira Chiesa | Adyuvante de vacunación, preparación y vacunas que lo contienen |
CA2894260A1 (en) | 2012-12-18 | 2014-06-26 | Glaxosmithkline Biologicals S.A. | Conjugates for protecting against diphtheria and/or tetanus |
CN105338999B (zh) | 2013-03-13 | 2020-02-28 | 诺华股份有限公司 | 乙型流感病毒重配 |
EP2801372A3 (en) | 2013-05-10 | 2015-02-18 | Novartis AG | Avoiding narcolepsy risk in influenza vaccines |
DE202013005100U1 (de) | 2013-06-05 | 2013-08-26 | Novartis Ag | Influenza Virus Reassortierung |
DE202013005130U1 (de) | 2013-06-05 | 2013-09-10 | Novartis Ag | Influenza Virus Reassortierung |
EP3004332A2 (en) | 2013-06-06 | 2016-04-13 | Novartis AG | Influenza virus reassortment |
NZ733383A (en) | 2013-09-19 | 2022-12-23 | Zoetis Services Llc | Oil-based adjuvants |
RU2016114713A (ru) | 2013-10-17 | 2017-11-20 | Зоэтис Сервисиз Ллс | Способы и композиции для лечения s. equi инфекции |
EP2870974A1 (en) | 2013-11-08 | 2015-05-13 | Novartis AG | Salmonella conjugate vaccines |
CN105899199A (zh) * | 2013-11-26 | 2016-08-24 | 硕腾服务有限责任公司 | 诱导免疫应答的组合物 |
US10280199B2 (en) | 2014-02-07 | 2019-05-07 | Phibro Animal Health Corporation | Coronavirus proteins and antigens |
KR20160132109A (ko) | 2014-03-26 | 2016-11-16 | 글락소스미스클라인 바이오로지칼즈 에스.에이. | 돌연변이 스태필로코쿠스 항원 |
CN104013955B (zh) * | 2014-06-18 | 2016-02-24 | 中国科学院过程工程研究所 | 一种不含表面活性剂的水包油乳液及其用途 |
JP7113620B2 (ja) * | 2015-01-16 | 2022-08-05 | ゾエティス・サービシーズ・エルエルシー | 口蹄疫ワクチン |
BR112017028011A2 (pt) | 2015-06-26 | 2018-08-28 | Seqirus Uk Ltd | vacinas de gripe correspondentes antigenicamente |
US10416171B2 (en) | 2015-07-07 | 2019-09-17 | Seqirus UK Limited | Influenza potency assays |
WO2017083820A1 (en) | 2015-11-13 | 2017-05-18 | Pds Biotechnology Corporation | Lipids as synthetic vectors to enhance antigen processing and presentation ex-vivo in dendritic cell therapy |
CN108697782A (zh) * | 2016-03-23 | 2018-10-23 | 英特维特国际股份有限公司 | 针对pcv2病毒和猪肺炎支原体感染的组合疫苗 |
US20200405846A1 (en) * | 2016-05-10 | 2020-12-31 | The Regents Of The University Of Michigan | Emulsion adjuvant for intramuscular, intradermal and subcutaneous administration |
CA3022006A1 (en) * | 2016-05-11 | 2017-11-16 | Phibro Animal Health Corporation | A composition comprising antigens and a mucosal adjuvant and a method for using |
US10279031B2 (en) | 2016-05-11 | 2019-05-07 | Phibro Animal Health Corporation | Composition comprising antigens and a mucosal adjuvant and a method for using |
US11547672B2 (en) | 2018-09-14 | 2023-01-10 | Massachusetts Institute Of Technology | Nanoparticle vaccine adjuvant and methods of use thereof |
WO2020154595A1 (en) | 2019-01-24 | 2020-07-30 | Massachusetts Institute Of Technology | Nucleic acid nanostructure platform for antigen presentation and vaccine formulations formed therefrom |
AU2020389047A1 (en) | 2019-11-18 | 2022-06-02 | Seqirus Pty Ltd. | Method for producing reassortant influenza viruses |
TW202206098A (zh) * | 2020-08-11 | 2022-02-16 | 美商碩騰服務公司 | 抗冠狀病毒疫苗 |
US20230190920A1 (en) | 2021-12-19 | 2023-06-22 | Massachusetts Institute Of Technology | Compositions and methods for long-lasting germinal center responses to a priming immunization |
WO2023154960A1 (en) | 2022-02-14 | 2023-08-17 | University Of Georgia Research Foundation, Inc. | Pan-pneumovirus vaccine compositions and methods of use thereof |
Family Cites Families (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4310550A (en) | 1979-10-26 | 1982-01-12 | Pfizer Inc. | Lipid amines formulated with fat or lipid emulsions as vaccine adjuvants |
US4908154A (en) | 1981-04-17 | 1990-03-13 | Biotechnology Development Corporation | Method of forming a microemulsion |
US5084269A (en) | 1986-11-06 | 1992-01-28 | Kullenberg Fred W | Adjuvant for dose treatment with antigens |
US5376369A (en) | 1987-11-03 | 1994-12-27 | Syntex (U.S.A.) Inc. | Vaccine adjuvant |
NZ230747A (en) * | 1988-09-30 | 1992-05-26 | Bror Morein | Immunomodulating matrix comprising a complex of at least one lipid and at least one saponin; certain glycosylated triterpenoid saponins derived from quillaja saponaria molina |
WO1990014837A1 (en) | 1989-05-25 | 1990-12-13 | Chiron Corporation | Adjuvant formulation comprising a submicron oil droplet emulsion |
US5951988A (en) | 1993-03-30 | 1999-09-14 | University Of Saskatchewan | Adjuvant formulation with enhanced immunogenic activity, and related compositions and methods |
US5961970A (en) | 1993-10-29 | 1999-10-05 | Pharmos Corporation | Submicron emulsions as vaccine adjuvants |
UA56132C2 (uk) * | 1995-04-25 | 2003-05-15 | Смітклайн Бічем Байолоджікалс С.А. | Композиція вакцини (варіанти), спосіб стабілізації qs21 відносно гідролізу (варіанти), спосіб приготування композиції вакцини |
US5690942A (en) | 1995-06-02 | 1997-11-25 | American Home Products Corporation | Adjuvants for viral vaccines |
US5718904A (en) | 1995-06-02 | 1998-02-17 | American Home Products Corporation | Adjuvants for viral vaccines |
US6080725A (en) | 1997-05-20 | 2000-06-27 | Galenica Pharmaceuticals, Inc. | Immunostimulating and vaccine compositions employing saponin analog adjuvants and uses thereof |
GB9718901D0 (en) * | 1997-09-05 | 1997-11-12 | Smithkline Beecham Biolog | Vaccine |
EP1009382B1 (en) * | 1997-09-05 | 2003-06-18 | GlaxoSmithKline Biologicals S.A. | Oil in water emulsions containing saponins |
EP0953641A3 (en) * | 1998-03-26 | 2002-03-13 | Pfizer Products Inc. | Polynucleotide molecules encoding neospora proteins |
GB9817052D0 (en) * | 1998-08-05 | 1998-09-30 | Smithkline Beecham Biolog | Vaccine |
DE60017211T2 (de) * | 1999-02-17 | 2005-06-02 | Pfizer Products Inc., Groton | Fusionsproteine mit Trägern welche eine doppelte Immunantwort induzieren |
WO2000062800A2 (en) * | 1999-04-19 | 2000-10-26 | Smithkline Beecham Biologicals Sa | Adjuvant composition comprising saponin and an immunostimulatory oligonucleotide |
DE10106446A1 (de) * | 2001-02-09 | 2002-10-10 | Haarmann & Reimer Gmbh | Verfahren zur Herstellung blauer Mikrokapseln |
PL216541B1 (pl) * | 2002-08-26 | 2014-04-30 | Pfizer Prod Inc | Kompozycja immunogenna oraz kompozycja do szczepienia i jej zastosowanie |
ATE395077T1 (de) * | 2003-01-29 | 2008-05-15 | Pfizer Prod Inc | Hundeimpfstoffe gegen bordetella bronchiseptica |
JP2006522090A (ja) * | 2003-04-04 | 2006-09-28 | ファイザー・プロダクツ・インク | マイクロ流動化された水中油形エマルジョン及びワクチン組成物 |
KR20070008625A (ko) * | 2004-04-05 | 2007-01-17 | 화이자 프로덕츠 인코포레이티드 | 미세유체화된 수중유 유화액 및 백신 조성물 |
-
2005
- 2005-03-24 KR KR1020067020930A patent/KR20070008625A/ko not_active Application Discontinuation
- 2005-03-24 KR KR1020097009238A patent/KR20090051129A/ko not_active Application Discontinuation
- 2005-03-24 JP JP2007506850A patent/JP5393978B2/ja active Active
- 2005-03-24 ES ES05718292T patent/ES2409782T3/es active Active
- 2005-03-24 KR KR1020087031330A patent/KR101143060B1/ko active IP Right Grant
- 2005-03-24 KR KR1020087018863A patent/KR20080073376A/ko not_active Application Discontinuation
- 2005-03-24 AU AU2005230708A patent/AU2005230708B2/en active Active
- 2005-03-24 RU RU2006135121A patent/RU2347586C2/ru active
- 2005-03-24 PT PT57182925T patent/PT1742659E/pt unknown
- 2005-03-24 PL PL05718292T patent/PL1742659T3/pl unknown
- 2005-03-24 EP EP20100178441 patent/EP2269644A3/en not_active Withdrawn
- 2005-03-24 BR BRPI0509606A patent/BRPI0509606B1/pt active IP Right Grant
- 2005-03-24 CA CA2561914A patent/CA2561914C/en active Active
- 2005-03-24 CN CN2005800119857A patent/CN1997390B/zh active Active
- 2005-03-24 WO PCT/IB2005/000804 patent/WO2005097181A1/en active Application Filing
- 2005-03-24 SI SI200531727T patent/SI1742659T1/sl unknown
- 2005-03-24 UA UAA200610518A patent/UA89631C2/ru unknown
- 2005-03-24 KR KR1020117022798A patent/KR20110132416A/ko not_active Application Discontinuation
- 2005-03-24 DK DK05718292T patent/DK1742659T3/da active
- 2005-03-24 EP EP20050718292 patent/EP1742659B1/en active Active
- 2005-03-24 NZ NZ550152A patent/NZ550152A/en unknown
- 2005-04-01 US US11/096,831 patent/US7122191B2/en active Active
- 2005-04-01 TW TW94110524A patent/TWI301067B/zh active
- 2005-04-04 AR ARP050101316 patent/AR048822A1/es not_active Application Discontinuation
- 2005-04-04 UY UY28840A patent/UY28840A1/es not_active Application Discontinuation
-
2006
- 2006-10-02 ZA ZA200608200A patent/ZA200608200B/xx unknown
- 2006-11-02 NO NO20065039A patent/NO341034B1/no unknown
-
2007
- 2007-12-20 HK HK07113918A patent/HK1108830A1/xx unknown
-
2011
- 2011-04-13 JP JP2011089018A patent/JP2011168605A/ja active Pending
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ZA200608200B (en) | Microfluidized oil-in-water emulsions and vaccine compositions | |
HK1086484A1 (en) | Microfluidized oil-in-water emulsions and vaccine compositions | |
GB0503684D0 (en) | Emulsifiers and emulsions | |
IL178631A0 (en) | Oil-in-water emulsion for delivery | |
HK1110516A1 (en) | Solid oil-in-water emulsion | |
EP1997474A4 (en) | SOLAR PROTECTION PREPARATION OF WATER EMULSION TYPE IN OIL | |
HK1114038A1 (en) | Solid skin care composition comprising multiple layers based on water-in- oil emulsions | |
DE602005001478D1 (de) | Oel-in-Wasser emulgierte Zusammensetzung | |
GB0422525D0 (en) | Dermatological compositions and methods | |
HK1102600A1 (en) | Novel anti-igf-ir antibodies and uses thereof | |
HK1141709A1 (en) | Oil-in-water emulsion type sunscreen preparation | |
HK1112179A1 (en) | Oily cosmetic preparation | |
EP1864659A4 (en) | A LIGNAN COMPOUND OIL-IN-WATER EMULSION AND COMPOSITION COMPRISING THEREOF | |
HK1126120A1 (en) | Water-in-oil emulsion type sunscreen preparation | |
EP1773386A4 (en) | VACCINE COMPOSITIONS AND CORRESPONDING METHODS | |
IL179296A0 (en) | Amphiphilic polymer compositions and their use | |
EP1704858A4 (en) | PROPOFOL-CONTAINING FAT-EMULSION PREPARATION | |
PL1762219T3 (pl) | Fotoochronne i/lub fotoimmunoochronne kompozycje do skóry i ich zastosowania | |
EP1800548A4 (en) | OIL-IN-WATER EMULSIFICATION COMPOSITION FOR COOKED RICE, AS WELL AS COOKED RICE, WHERE IT IS USED | |
DE602004028074D1 (de) | Öl-in-Wasser emulgierte kosmetische Zusammensetzung | |
EP1716765A4 (en) | EMULSION OF AQUEOUS TYPE | |
PL1637165T3 (pl) | Medyczna emulsja chłodząca | |
GB0416890D0 (en) | Silicone emulsions and their preparation | |
EP1634505A4 (en) | OIL TYPE EMULSION COMPOSITION IN ACIDIC WATER | |
HK1107256A1 (en) | Compositions containing nicorandil, preparation method and use |