GB201017519D0 - Vaccines - Google Patents
VaccinesInfo
- Publication number
- GB201017519D0 GB201017519D0 GBGB1017519.8A GB201017519A GB201017519D0 GB 201017519 D0 GB201017519 D0 GB 201017519D0 GB 201017519 A GB201017519 A GB 201017519A GB 201017519 D0 GB201017519 D0 GB 201017519D0
- Authority
- GB
- United Kingdom
- Prior art keywords
- blebs
- immunogens
- strains
- vaccines
- hyperblebbing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
- C07K14/255—Salmonella (G)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/025—Enterobacteriales, e.g. Enterobacter
- A61K39/0275—Salmonella
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
- C12P1/04—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/522—Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
- A61K2039/541—Mucosal route
- A61K2039/543—Mucosal route intranasal
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Abstract
Hyperblebbing Salmonella strains are generated by disrupting one or more components of the Tol-Pal system, such as TolR. The blebs from these strains are useful immunogens for vaccination. The individual proteins found in these blebs can also be used as immunogens.
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB1017519.8A GB201017519D0 (en) | 2010-10-15 | 2010-10-15 | Vaccines |
PCT/IB2011/054569 WO2012049662A1 (en) | 2010-10-15 | 2011-10-14 | Hyperblebbing salmonella strains |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB1017519.8A GB201017519D0 (en) | 2010-10-15 | 2010-10-15 | Vaccines |
Publications (1)
Publication Number | Publication Date |
---|---|
GB201017519D0 true GB201017519D0 (en) | 2010-12-01 |
Family
ID=43333951
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GBGB1017519.8A Ceased GB201017519D0 (en) | 2010-10-15 | 2010-10-15 | Vaccines |
Country Status (2)
Country | Link |
---|---|
GB (1) | GB201017519D0 (en) |
WO (1) | WO2012049662A1 (en) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2870974A1 (en) | 2013-11-08 | 2015-05-13 | Novartis AG | Salmonella conjugate vaccines |
WO2015142875A1 (en) * | 2014-03-17 | 2015-09-24 | The Trustees Of The University Of Pennsylvania | Compositions and methods using modified salmonella |
EP3310381B1 (en) * | 2015-06-16 | 2023-06-07 | GlaxoSmithKline Biologicals SA | Immunogenic compositions |
EP4116316A1 (en) * | 2015-07-04 | 2023-01-11 | Evaxion Biotech A/S | Proteins and nucleic acids useful in vaccines targeting pseudomonas aeruginosa |
EP3749364A1 (en) | 2018-02-09 | 2020-12-16 | Consejo Nacional de Investigaciones Científicas Y Técnicas (CONICET) | Immunomodulating and immunostimulating polypeptides for drug-delivery |
EP3581201A1 (en) * | 2018-06-15 | 2019-12-18 | GlaxoSmithKline Biologicals S.A. | Escherichia coli o157:h7 proteins and uses thereof |
KR20210092224A (en) * | 2018-11-10 | 2021-07-23 | 브하라트 바이오테크 인터내셔날 리미티드 | Multivalent Glycoconjugate Immunogenic Composition |
EP3808372A1 (en) * | 2019-10-17 | 2021-04-21 | GlaxoSmithKline Biologicals S.A. | Novel vaccine compositions |
GB202112149D0 (en) * | 2021-08-24 | 2021-10-06 | Glaxosmithkline Biologicals Sa | Shigellla vaccine |
Family Cites Families (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE8205892D0 (en) | 1982-10-18 | 1982-10-18 | Bror Morein | IMMUNOGENT MEMBRANE PROTEIN COMPLEX, SET FOR PREPARATION AND USE THEREOF |
US6090406A (en) | 1984-04-12 | 2000-07-18 | The Liposome Company, Inc. | Potentiation of immune responses with liposomal adjuvants |
US5916588A (en) | 1984-04-12 | 1999-06-29 | The Liposome Company, Inc. | Peptide-containing liposomes, immunogenic liposomes and methods of preparation and use |
US5057540A (en) | 1987-05-29 | 1991-10-15 | Cambridge Biotech Corporation | Saponin adjuvant |
AU631377B2 (en) | 1988-08-25 | 1992-11-26 | Liposome Company, Inc., The | Affinity associated vaccine |
JPH0832638B2 (en) | 1989-05-25 | 1996-03-29 | カイロン コーポレイション | Adjuvant formulation comprising submicron oil droplet emulsion |
HU219808B (en) | 1992-06-25 | 2001-08-28 | Smithkline Beecham Biologicals S.A. | Vaccine composition containing adjuvant and process for preparation thereof |
DE69405551T3 (en) | 1993-03-23 | 2005-10-20 | Smithkline Beecham Biologicals S.A. | 3-0-DEAZYLATED MONOPHOSPHORYL LIPID A-CONTAINING VACCINE COMPOSITIONS |
AU5543294A (en) | 1993-10-29 | 1995-05-22 | Pharmos Corp. | Submicron emulsions as vaccine adjuvants |
GB9326174D0 (en) | 1993-12-22 | 1994-02-23 | Biocine Sclavo | Mucosal adjuvant |
GB9326253D0 (en) | 1993-12-23 | 1994-02-23 | Smithkline Beecham Biolog | Vaccines |
US6429199B1 (en) | 1994-07-15 | 2002-08-06 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules for activating dendritic cells |
US6207646B1 (en) | 1994-07-15 | 2001-03-27 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules |
US6239116B1 (en) | 1994-07-15 | 2001-05-29 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules |
AUPM873294A0 (en) | 1994-10-12 | 1994-11-03 | Csl Limited | Saponin preparations and use thereof in iscoms |
UA56132C2 (en) | 1995-04-25 | 2003-05-15 | Смітклайн Бічем Байолоджікалс С.А. | Vaccine composition (variants), method for stabilizing qs21 providing resistance against hydrolysis (variants), method for manufacturing vaccine |
GB9513261D0 (en) | 1995-06-29 | 1995-09-06 | Smithkline Beecham Biolog | Vaccines |
ATE441432T1 (en) | 1997-03-10 | 2009-09-15 | Ottawa Hospital Res Inst | USE OF NON-METHYLATED CPG DINUCLEOTIDE IN COMBINATION WITH ALUMINUM AS ADJUVANTS |
US6818222B1 (en) | 1997-03-21 | 2004-11-16 | Chiron Corporation | Detoxified mutants of bacterial ADP-ribosylating toxins as parenteral adjuvants |
US6080725A (en) | 1997-05-20 | 2000-06-27 | Galenica Pharmaceuticals, Inc. | Immunostimulating and vaccine compositions employing saponin analog adjuvants and uses thereof |
GB9712347D0 (en) | 1997-06-14 | 1997-08-13 | Smithkline Beecham Biolog | Vaccine |
EP1009382B1 (en) | 1997-09-05 | 2003-06-18 | GlaxoSmithKline Biologicals S.A. | Oil in water emulsions containing saponins |
GB9725084D0 (en) | 1997-11-28 | 1998-01-28 | Medeva Europ Ltd | Vaccine compositions |
KR100585408B1 (en) | 1998-02-12 | 2006-06-01 | 와이어쓰 홀딩스 코포레이션 | Pneumococcal and meningococcal vaccines formulated with interleukin-12 |
US6303114B1 (en) | 1998-03-05 | 2001-10-16 | The Medical College Of Ohio | IL-12 enhancement of immune responses to T-independent antigens |
US6562798B1 (en) | 1998-06-05 | 2003-05-13 | Dynavax Technologies Corp. | Immunostimulatory oligonucleotides with modified bases and methods of use thereof |
GB9817052D0 (en) | 1998-08-05 | 1998-09-30 | Smithkline Beecham Biolog | Vaccine |
AU3108001A (en) | 2000-01-20 | 2001-12-24 | Coley Pharmaceutical Group, Inc. | Immunostimulatory nucleic acids for inducing a th2 immune response |
AU2001264935A1 (en) | 2000-05-24 | 2001-12-03 | University Of Maryland Biotechnology Institute | Method for introducing and expressing genes in animal cells, and bacterial blebsfor use in same |
WO2002026757A2 (en) | 2000-09-26 | 2002-04-04 | Hybridon, Inc. | Modulation of immunostimulatory activity of immunostimulatory oligonucleotide analogs by positional chemical changes |
GB0103171D0 (en) * | 2001-02-08 | 2001-03-28 | Smithkline Beecham Biolog | Vaccine composition |
WO2003035836A2 (en) | 2001-10-24 | 2003-05-01 | Hybridon Inc. | Modulation of immunostimulatory properties of oligonucleotide-based compounds by optimal presentation of 5' ends |
AU2004224746B2 (en) | 2003-03-24 | 2009-04-23 | Valneva Austria Gmbh | Improved vaccines |
DK1742659T3 (en) | 2004-04-05 | 2013-06-03 | Zoetis P Llc | Microfluidized oil-in-water emulsions and vaccine compositions |
US20060228369A1 (en) | 2005-04-11 | 2006-10-12 | Program For Appropriate Technology In Health | Stabilization and preservation of temperature-sensitive vaccines |
US7691368B2 (en) | 2005-04-15 | 2010-04-06 | Merial Limited | Vaccine formulations |
US8703095B2 (en) | 2005-07-07 | 2014-04-22 | Sanofi Pasteur S.A. | Immuno-adjuvant emulsion |
GB0917003D0 (en) | 2009-09-28 | 2009-11-11 | Novartis Vaccines Inst For Global Health Srl | Purification of bacterial vesicles |
GB0917002D0 (en) | 2009-09-28 | 2009-11-11 | Novartis Vaccines Inst For Global Health Srl | Improved shigella blebs |
-
2010
- 2010-10-15 GB GBGB1017519.8A patent/GB201017519D0/en not_active Ceased
-
2011
- 2011-10-14 WO PCT/IB2011/054569 patent/WO2012049662A1/en active Application Filing
Also Published As
Publication number | Publication date |
---|---|
WO2012049662A1 (en) | 2012-04-19 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
GB0917002D0 (en) | Improved shigella blebs | |
GB201017519D0 (en) | Vaccines | |
AU2015296298A8 (en) | Flagellin-based agents and uses including effective vaccination | |
MY180714A (en) | Factor viii chimeric and hybrid polypeptides, and methods of use thereof | |
MX2016002571A (en) | Transduction buffer. | |
EA201291157A1 (en) | MULTIVALENT VACCINES WITH SYNTHETIC NANOSATORS | |
EA201300915A1 (en) | NEW EUROPEAN PRRSV STRAIN | |
PH12016502220A1 (en) | Means and methods for treating cmv | |
MX349630B (en) | Alpha-amylases. | |
MX344972B (en) | Immunostimulatory oligonucleotides. | |
CY1117214T1 (en) | COMPOSITION FOR CONTROLLED OVENTION STUDY | |
TN2013000378A1 (en) | Anti - sclerostin antibody crystals and formulations thereof | |
MX2020002544A (en) | Glycopyrrolate salts. | |
MX2021014663A (en) | Compound targeting il-23a and tnf-alpha and uses thereof. | |
PH12015501101A1 (en) | Method for eliciting an immune response to an immunogen | |
MY191539A (en) | Streptococcal vaccine | |
SG10201900041VA (en) | Meningococcus vaccines | |
IN2014MU00455A (en) | ||
MA37749B1 (en) | Vaccines against bluetongue and African horse sickness virus | |
MX2013003859A (en) | Picropodophyllin polymorphs b or c for use in cancer therapy. | |
MX367773B (en) | Solid salt form of alpha-6-mpeg6-o-hydroxycodone as opioid agonists and uses thereof. | |
MX2018005134A (en) | Fviii formulation. | |
MX2015012124A (en) | Compositions and methods for targeting o-linked n-acetylglucosamine transferase and promoting wound healing. | |
EP2879705A4 (en) | PEPTIDE VACCINES BASED ON THE EGFRvIII SEQUENCE FOR THE TREATMENT OF TUMORS | |
IN2013CH05865A (en) |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AT | Applications terminated before publication under section 16(1) |