PL2464658T3 - Immunogeny z Escherichia coli o zniesionej toksyczności - Google Patents

Immunogeny z Escherichia coli o zniesionej toksyczności

Info

Publication number
PL2464658T3
PL2464658T3 PL10752175T PL10752175T PL2464658T3 PL 2464658 T3 PL2464658 T3 PL 2464658T3 PL 10752175 T PL10752175 T PL 10752175T PL 10752175 T PL10752175 T PL 10752175T PL 2464658 T3 PL2464658 T3 PL 2464658T3
Authority
PL
Poland
Prior art keywords
escherichia coli
immunogens
detoxified
detoxified escherichia
coli immunogens
Prior art date
Application number
PL10752175T
Other languages
English (en)
Inventor
Laura Serino
Maria Rita Fontana
Danilo Gomes Moriel
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of PL2464658T3 publication Critical patent/PL2464658T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/025—Enterobacteriales, e.g. Enterobacter
    • A61K39/0258—Escherichia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/245—Escherichia (G)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/24—Metalloendopeptidases (3.4.24)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Mycology (AREA)
  • General Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
PL10752175T 2009-07-16 2010-07-16 Immunogeny z Escherichia coli o zniesionej toksyczności PL2464658T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US22621909P 2009-07-16 2009-07-16
US29065409P 2009-12-29 2009-12-29
EP10752175.9A EP2464658B1 (en) 2009-07-16 2010-07-16 Detoxified escherichia coli immunogens
PCT/IB2010/002043 WO2011007257A1 (en) 2009-07-16 2010-07-16 Detoxified escherichia coli immunogens

Publications (1)

Publication Number Publication Date
PL2464658T3 true PL2464658T3 (pl) 2015-03-31

Family

ID=43126814

Family Applications (1)

Application Number Title Priority Date Filing Date
PL10752175T PL2464658T3 (pl) 2009-07-16 2010-07-16 Immunogeny z Escherichia coli o zniesionej toksyczności

Country Status (17)

Country Link
US (2) US8871214B2 (pl)
EP (2) EP2464658B1 (pl)
JP (1) JP2012532626A (pl)
CN (1) CN102770443A (pl)
AU (1) AU2010272243A1 (pl)
CA (1) CA2768343A1 (pl)
DK (1) DK2464658T3 (pl)
ES (2) ES2526996T3 (pl)
HR (1) HRP20141270T1 (pl)
IL (1) IL217539A0 (pl)
MX (1) MX2012000734A (pl)
PL (1) PL2464658T3 (pl)
PT (1) PT2464658E (pl)
SG (1) SG178035A1 (pl)
SI (1) SI2464658T1 (pl)
WO (1) WO2011007257A1 (pl)
ZA (1) ZA201200833B (pl)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
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WO2013038385A2 (en) 2011-09-14 2013-03-21 Novartis Ag Escherichia coli vaccine combination
WO2014102694A1 (en) * 2012-12-24 2014-07-03 Novartis Ag Novel mucinase for use in therapy or prophylaxis
EP3153519A1 (en) * 2015-10-06 2017-04-12 Syddansk Universitet Glycosylated yghj polypeptides from enterotoxigenic escherichia coli (etec)
KR20190139209A (ko) * 2017-02-13 2019-12-17 알렉산드레 에듀아르도 노윌 면역시스템을 조절하기 위한 면역원성 조성물 및 개체에서의 세균 감염 치료 방법
US11260119B2 (en) 2018-08-24 2022-03-01 Pfizer Inc. Escherichia coli compositions and methods thereof
US12138302B2 (en) 2020-10-27 2024-11-12 Pfizer Inc. Escherichia coli compositions and methods thereof
US12357681B2 (en) 2020-12-23 2025-07-15 Pfizer Inc. E. coli FimH mutants and uses thereof
AU2023362022A1 (en) 2022-10-19 2025-05-01 Glyprovac Aps Glycosylated yghj polypeptides from uropathogenic e. coli
WO2025219177A1 (en) 2024-04-18 2025-10-23 Glyprovac Aps Optimized plasmids for expression of yghj polypeptides

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EP2464658A1 (en) 2012-06-20
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US20150110830A1 (en) 2015-04-23
DK2464658T3 (en) 2014-12-15
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ES2670799T3 (es) 2018-06-01
CA2768343A1 (en) 2011-01-20
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ZA201200833B (en) 2014-08-27
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IL217539A0 (en) 2012-02-29
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