US7893101B2
(en)
|
2002-03-20 |
2011-02-22 |
Celgene Corporation |
Solid forms comprising (+)-2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione, compositions thereof, and uses thereof
|
US7407955B2
(en)
|
2002-08-21 |
2008-08-05 |
Boehringer Ingelheim Pharma Gmbh & Co., Kg |
8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions
|
WO2004078116A2
(en)
*
|
2003-03-03 |
2004-09-16 |
Array Biopharma, Inc. |
P38 inhibitors and methods of use thereof
|
US7135575B2
(en)
*
|
2003-03-03 |
2006-11-14 |
Array Biopharma, Inc. |
P38 inhibitors and methods of use thereof
|
US7344716B2
(en)
*
|
2003-05-13 |
2008-03-18 |
Depuy Spine, Inc. |
Transdiscal administration of specific inhibitors of pro-inflammatory cytokines
|
US7553827B2
(en)
*
|
2003-08-13 |
2009-06-30 |
Depuy Spine, Inc. |
Transdiscal administration of cycline compounds
|
US8273347B2
(en)
*
|
2003-05-13 |
2012-09-25 |
Depuy Spine, Inc. |
Autologous treatment of degenerated disc with cells
|
US7429378B2
(en)
*
|
2003-05-13 |
2008-09-30 |
Depuy Spine, Inc. |
Transdiscal administration of high affinity anti-MMP inhibitors
|
JP4977837B2
(ja)
*
|
2003-09-10 |
2012-07-18 |
アイカジェン, インコーポレイテッド |
カリウム・チャネル・モジュレーターとしての縮合環式複素環
|
JP4956191B2
(ja)
*
|
2003-10-17 |
2012-06-20 |
インサイト コーポレーション |
マトリックスメタロプロテイナーゼの阻害剤としての置換環状ヒドロキサメート
|
US8895540B2
(en)
*
|
2003-11-26 |
2014-11-25 |
DePuy Synthes Products, LLC |
Local intraosseous administration of bone forming agents and anti-resorptive agents, and devices therefor
|
CA2548374C
(en)
|
2003-12-23 |
2014-05-27 |
Astex Therapeutics Limited |
Pyrazole derivatives as protein kinase modulators
|
US7501426B2
(en)
|
2004-02-18 |
2009-03-10 |
Boehringer Ingelheim International Gmbh |
8-[3-amino-piperidin-1-yl]-xanthines, their preparation and their use as pharmaceutical compositions
|
JP2007523938A
(ja)
*
|
2004-02-27 |
2007-08-23 |
エフ.ホフマン−ラ ロシュ アーゲー |
ピラゾールの縮合誘導体
|
KR100844864B1
(ko)
*
|
2004-02-27 |
2008-07-09 |
에프. 호프만-라 로슈 아게 |
헤테로아릴-융합 피라졸로 유도체
|
JP2007523937A
(ja)
|
2004-02-27 |
2007-08-23 |
エフ.ホフマン−ラ ロシュ アーゲー |
インダゾール誘導体およびそれを含む医薬組成物
|
AU2005274937B2
(en)
|
2004-07-15 |
2011-08-18 |
Medivir Ab |
IAP binding compounds
|
AU2005273612B2
(en)
*
|
2004-08-12 |
2010-10-14 |
Pfizer Inc. |
Triazolopyridinylsulfanyl derivatives as p38 map kinase inhibitors
|
EP1647549A1
(en)
*
|
2004-10-14 |
2006-04-19 |
Laboratoire Theramex |
Indazoles, benzisoxazoles and benzisothiazoles as estrogenic agents
|
DE102004054054A1
(de)
|
2004-11-05 |
2006-05-11 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Verfahren zur Herstellung chiraler 8-(3-Amino-piperidin-1-yl)-xanthine
|
EP2385038A1
(en)
|
2005-02-25 |
2011-11-09 |
Tetralogic Pharmaceuticals Corporation |
Dimeric IAP inhibitors
|
WO2006103568A2
(en)
*
|
2005-03-22 |
2006-10-05 |
Innate Pharma |
NEW CLASS OF Ϝδ T CELLS ACTIVATORS AND USE THEREOF
|
WO2006123182A2
(en)
*
|
2005-05-17 |
2006-11-23 |
Merck Sharp & Dohme Limited |
Cyclohexyl sulphones for treatment of cancer
|
MX2007014502A
(es)
|
2005-05-26 |
2008-02-07 |
Metabasis Therapeutics Inc |
Tiromimeticos para el tratamiento de enfermedades del higado graso.
|
WO2006136821A1
(en)
*
|
2005-06-22 |
2006-12-28 |
Astex Therapeutics Limited |
Pharmaceutical compounds
|
US8541461B2
(en)
*
|
2005-06-23 |
2013-09-24 |
Astex Therapeutics Limited |
Pharmaceutical combinations comprising pyrazole derivatives as protein kinase modulators
|
ITRM20050344A1
(it)
*
|
2005-06-30 |
2007-01-01 |
Luca Maria De |
Sali o complessi di sostanze metil-donatrici con acido fitico o suoi derivati e relativo metodo di sintesi.
|
DE102005035891A1
(de)
|
2005-07-30 |
2007-02-08 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
8-(3-Amino-piperidin-1-yl)-xanthine, deren Herstellung und deren Verwendung als Arzneimittel
|
ATE512145T1
(de)
*
|
2005-08-11 |
2011-06-15 |
Vertex Pharma |
Modulatoren des cystic fibrosis transmembrane conductance regulators
|
BRPI0615272A2
(pt)
*
|
2005-08-25 |
2009-08-04 |
Hoffmann La Roche |
inibidores de p38 map kinase e métodos para uso dos mesmos
|
MX2008002588A
(es)
*
|
2005-08-25 |
2008-03-18 |
Hoffmann La Roche |
Inhibidores de p38-map-cinasa y los metodos para utilizarlos.
|
PL1944290T3
(pl)
*
|
2005-09-14 |
2014-07-31 |
Ayumi Pharmaceutical Corp |
Nowa pochodna 1-2-dihydrochinoliny mająca aktywność wiązania glukokortykoidowego receptora
|
WO2007031977A2
(en)
*
|
2005-09-16 |
2007-03-22 |
Ranbaxy Laboratories Limited |
Substituted pyrazolo [3,4-b]pyridines as phosphodiesterase inhibitors
|
EP1934219A1
(en)
|
2005-09-16 |
2008-06-25 |
Ranbaxy Laboratories Limited |
Substituted pyrazolo [3,4-b] pyridines as phosphodiesterase inhibitors
|
EP1934191B1
(en)
*
|
2005-10-12 |
2012-03-28 |
Vertex Pharmaceuticals, Inc. |
Biphenyl derivatives as modulators of voltage gated ion channels
|
WO2007047397A2
(en)
*
|
2005-10-13 |
2007-04-26 |
Smithkline Beecham Corporation |
Phenol ethers as modulators of the opioid receptors
|
RU2428421C2
(ru)
|
2005-11-15 |
2011-09-10 |
Эррей Байофарма Инк. |
Производные n4-фенилхиназолин-4-амина и родственные соединения в качестве ингибиторов рецепторной тирозинкиназы типа erbb для лечения гиперпролиферативных заболеваний
|
UA94921C2
(en)
*
|
2005-12-08 |
2011-06-25 |
Новартис Аг |
1-orthofluorophenyl substituted 1, 2, 5-thiazolidinedione derivatives as ptp-as inhibitors
|
KR20080098490A
(ko)
*
|
2006-01-13 |
2008-11-10 |
파마시클릭스, 인코포레이티드 |
티로신 키나제 억제제 및 이의 용도
|
DK1981851T3
(da)
*
|
2006-01-31 |
2012-03-19 |
Array Biopharma Inc |
Kinaseinhibitorer og fremgangsmåder til anvendelse deraf
|
US8541406B2
(en)
*
|
2006-02-07 |
2013-09-24 |
Nv Remynd |
Thiadiazole derivatives for the treatment of neurodegenerative diseases
|
EP2540725A1
(de)
|
2006-05-04 |
2013-01-02 |
Boehringer Ingelheim International GmbH |
Polymorphe von 1-((4-Methyl-chinazolin-2-yl)methyl)-3-methyl-7-(2-butin-1-yl)-8-(3-(R)-amino-piperidin-1-yl)xanthin
|
PE20080251A1
(es)
|
2006-05-04 |
2008-04-25 |
Boehringer Ingelheim Int |
Usos de inhibidores de dpp iv
|
EP1852108A1
(en)
|
2006-05-04 |
2007-11-07 |
Boehringer Ingelheim Pharma GmbH & Co.KG |
DPP IV inhibitor formulations
|
US8338465B2
(en)
*
|
2006-06-08 |
2012-12-25 |
Cornell Research Foundation, Inc. |
Cyclic carboxylic acid rhodanine derivatives for the treatment and prevention of tuberculosis
|
US7727978B2
(en)
*
|
2006-08-24 |
2010-06-01 |
Bristol-Myers Squibb Company |
Cyclic 11-beta hydroxysteroid dehydrogenase type I inhibitors
|
WO2008032164A2
(en)
*
|
2006-09-12 |
2008-03-20 |
Pfizer Products Inc. |
Benzimidazolone derivatives
|
MX344418B
(es)
*
|
2006-09-25 |
2016-12-15 |
Ptc Therapeutics Inc |
Formas cristalinas del acido 3-[5- 2- fluorofenil)- [1,2,4] oxadiazol-3-il]- benzoico.
|
ES2416289T3
(es)
|
2006-11-14 |
2013-07-31 |
Santen Pharmaceutical Co., Ltd |
Nuevo derivado de 1,2-dihidroquinolina que tiene como sustituyentes un grupo alquilo inferior sustituido con fenilcalcógeno y un grupo fenilo introducido por un éster
|
TW200831085A
(en)
*
|
2006-12-13 |
2008-08-01 |
Merck & Co Inc |
Non-nucleoside reverse transcriptase inhibitors
|
JP2010516702A
(ja)
*
|
2007-01-18 |
2010-05-20 |
エヴォルヴァ エスアー |
置換1,3−ジオキサンのプロドラッグおよびそれらの使用
|
DE102007009494A1
(de)
*
|
2007-02-27 |
2008-08-28 |
Bayer Healthcare Ag |
Substituierte 4-Aryl-1, 4-dihydro-1,6-naphthyridinamide und ihre Verwendung
|
CN101669030B
(zh)
|
2007-03-08 |
2016-01-13 |
小利兰·斯坦福大学托管委员会 |
线粒体醛脱氢酶2调节剂和其使用方法
|
US8030344B2
(en)
*
|
2007-03-13 |
2011-10-04 |
Methylgene Inc. |
Inhibitors of histone deacetylase
|
GB0704932D0
(en)
|
2007-03-14 |
2007-04-25 |
Astex Therapeutics Ltd |
Pharmaceutical compounds
|
ATE524456T1
(de)
*
|
2007-03-23 |
2011-09-15 |
Abbott Gmbh & Co Kg |
Zur behandlung von erkrankungen, die auf eine modulation des serotonin-5-ht6-rezeptors ansprechen, geeignete chinolinverbindung
|
AU2008230816B2
(en)
*
|
2007-03-26 |
2014-09-04 |
University Of Southern California |
Methods and compositions for inducing apoptosis by stimulating ER stress
|
DK2152078T3
(da)
*
|
2007-04-27 |
2021-02-08 |
Cydex Pharmaceuticals Inc |
Formuleringer indeholdende clopidogrel og sulfoalkylethercyclodextrin og anvendelsesfremgangsmåder
|
EP2011786A1
(en)
*
|
2007-07-05 |
2009-01-07 |
Laboratorios del Dr. Esteve S.A. |
Indane-amine derivatives, their preparation and use as medicaments
|
DE102007032347A1
(de)
*
|
2007-07-11 |
2009-01-15 |
Bayer Healthcare Ag |
Aminoacyl-Prodrugs
|
WO2009015000A1
(en)
*
|
2007-07-25 |
2009-01-29 |
Array Biopharma Inc. |
Pyrazole urea derivatives used as kinase inhibitors
|
TW200908984A
(en)
*
|
2007-08-07 |
2009-03-01 |
Piramal Life Sciences Ltd |
Pyridyl derivatives, their preparation and use
|
WO2009053999A2
(en)
*
|
2007-08-07 |
2009-04-30 |
Cadila Healthcare Limited |
Sulfoximine derivatives as factor xa inhibitors
|
WO2009026579A1
(en)
*
|
2007-08-23 |
2009-02-26 |
Cornell Research Foundation, Inc. |
Proteasome inhibitors and their use in treating pathogen infection and cancer
|
WO2009036275A1
(en)
*
|
2007-09-13 |
2009-03-19 |
Link Medicine Corporation |
Treatment of neurodegenerative diseases using indatraline analogs
|
US10435356B1
(en)
|
2007-09-18 |
2019-10-08 |
Thermolife International, Llc |
Amino acid compositions
|
US10426750B1
(en)
|
2007-09-18 |
2019-10-01 |
Thermolife International, Llc |
Amino acid supplement formulations
|
US10646508B1
(en)
*
|
2007-09-18 |
2020-05-12 |
Thermolife International, Llc |
Method of safely administering nitrate dietary supplements and compositions
|
US8466187B2
(en)
|
2007-09-18 |
2013-06-18 |
Thermolife International, Llc |
Amino acid compositions
|
JP2011503232A
(ja)
|
2007-11-20 |
2011-01-27 |
ザ ブリガム アンド ウィメンズ ホスピタル インコーポレイテッド |
免疫応答の調節
|
FR2924712B1
(fr)
*
|
2007-12-06 |
2012-12-21 |
Univ Maine |
Derives du gossypol et de l'apogossypol, leurs preparations et leurs applications
|
EP2070929A1
(en)
|
2007-12-11 |
2009-06-17 |
Bayer Schering Pharma Aktiengesellschaft |
Alkynylaryl compounds and salts thereof, pharmaceutical compositions comprising same, methods of preparing same and uses of same
|
AR069650A1
(es)
*
|
2007-12-14 |
2010-02-10 |
Actelion Pharmaceuticals Ltd |
Derivados de aminopirazol como agonistas no peptidicos del receptor alx humano
|
US20090162351A1
(en)
*
|
2007-12-21 |
2009-06-25 |
Depuy Spine, Inc. |
Transdiscal administration of inhibitors of p38 MAP kinase
|
US8986696B2
(en)
*
|
2007-12-21 |
2015-03-24 |
Depuy Mitek, Inc. |
Trans-capsular administration of p38 map kinase inhibitors into orthopedic joints
|
AU2009217543A1
(en)
*
|
2008-02-25 |
2009-09-03 |
Merck Sharp & Dohme Corp. |
Tetrahydro-1H-pyrrolo fused pyridones
|
JP2011513329A
(ja)
*
|
2008-02-29 |
2011-04-28 |
アレイ バイオファーマ、インコーポレイテッド |
RAF阻害化合物として使用されるイミダゾ[4,5−b]ピリジン誘導体
|
JP5506776B2
(ja)
*
|
2008-03-25 |
2014-05-28 |
アフェクティス ファーマシューティカルズ アーゲー |
新規p2x7r拮抗薬及びその使用法
|
US20090246234A1
(en)
*
|
2008-04-01 |
2009-10-01 |
Benjamin Johnson |
Therapeutic Treatment Using Niacin for Skin Disorders
|
PE20140960A1
(es)
|
2008-04-03 |
2014-08-15 |
Boehringer Ingelheim Int |
Formulaciones que comprenden un inhibidor de dpp4
|
EP2116539A1
(en)
|
2008-04-25 |
2009-11-11 |
Laboratorios Del. Dr. Esteve, S.A. |
1-aryl-3-aminoalkoxy-pyrazoles as sigma ligands enhancing analgesic effects of opioids and attenuating the dependency thereof
|
WO2009144009A1
(en)
*
|
2008-05-26 |
2009-12-03 |
Medizinische Universität Innsbruck |
Medical intervention in haematological cancers
|
PT2730581T
(pt)
|
2008-06-17 |
2016-08-17 |
Millennium Pharm Inc |
Compostos de ésteres de boronato e suas composições farmacêuticas
|
EP2308842B1
(en)
*
|
2008-06-25 |
2013-10-23 |
Keio University |
DTCM glutarimide C-12 as iNOS and COX-2 inhibitor
|
UY32030A
(es)
|
2008-08-06 |
2010-03-26 |
Boehringer Ingelheim Int |
"tratamiento para diabetes en pacientes inapropiados para terapia con metformina"
|
JP2011530527A
(ja)
*
|
2008-08-06 |
2011-12-22 |
バーテックス ファーマシューティカルズ インコーポレイテッド |
アミノピリジンキナーゼ阻害剤
|
KR20190016601A
(ko)
|
2008-08-06 |
2019-02-18 |
베링거 인겔하임 인터내셔날 게엠베하 |
메트포르민 요법이 부적합한 환자에서의 당뇨병 치료
|
WO2010028175A1
(en)
|
2008-09-08 |
2010-03-11 |
The Board Of Trustees Of The Leland Stanford Junior University |
Modulators of aldehyde dehydrogenase activity and methods of use thereof
|
RU2011113823A
(ru)
*
|
2008-09-10 |
2012-10-20 |
БЕРИНГЕР ИНГЕЛЬХАЙМ ИНТЕРНАЦИОНАЛЬ ГмбХ (DE) |
Комбинированная терапия, предназначенная для лечения диабета и связанных с ним состояний
|
KR100905419B1
(ko)
*
|
2008-09-11 |
2009-07-02 |
연세대학교 산학협력단 |
세스퀴테르펜 유도체의 용도
|
CN102170873B
(zh)
*
|
2008-10-01 |
2014-07-30 |
诺华股份有限公司 |
用于治疗与hedgehog通路有关的病症的smoothened拮抗
|
WO2010041908A2
(ko)
*
|
2008-10-09 |
2010-04-15 |
(주)뉴트리 |
판두라틴 유도체 또는 보에센베르기아 판두라타 추출물의 신규한 용도
|
AR074797A1
(es)
*
|
2008-10-10 |
2011-02-16 |
Japan Tobacco Inc |
Compuesto de fluoreno , composiciones farmaceuticas , inhibidores de pdhk y pdhk2 , metodos de tratamiento , usos de los mismos y kit comercial
|
US20200155558A1
(en)
|
2018-11-20 |
2020-05-21 |
Boehringer Ingelheim International Gmbh |
Treatment for diabetes in patients with insufficient glycemic control despite therapy with an oral antidiabetic drug
|
WO2010062308A1
(en)
*
|
2008-10-28 |
2010-06-03 |
The Board Of Trustees Of The Leland Stanford Junior University |
Modulators of aldehyde dehydrogenase and methods of use thereof
|
DE102008059133A1
(de)
*
|
2008-11-26 |
2010-05-27 |
Merck Patent Gmbh |
Difluorphenyl-diacylhydrazid-derivate
|
KR20100060189A
(ko)
*
|
2008-11-27 |
2010-06-07 |
국립암센터 |
에타크리닉 산을 포함하는 트란스글루타미나제 관련 질환 예방 또는 치료용 조성물 및 그를 이용하는 트란스글루타미나제 관련 질환 예방 또는 치료 방법
|
US8362080B2
(en)
*
|
2008-12-18 |
2013-01-29 |
Baylor College Of Medicine |
Increasing glutathione levels for therapy
|
TWI432188B
(zh)
*
|
2008-12-19 |
2014-04-01 |
Merz Pharma Gmbh & Co Kgaa |
供治療發炎性皮膚疾病之1-胺基-烷基環己烷衍生物類
|
JP2012512848A
(ja)
|
2008-12-23 |
2012-06-07 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
有機化合物の塩の形態
|
TW201036975A
(en)
|
2009-01-07 |
2010-10-16 |
Boehringer Ingelheim Int |
Treatment for diabetes in patients with inadequate glycemic control despite metformin therapy
|
SI2376077T1
(sl)
*
|
2009-01-12 |
2017-09-29 |
Biokier Inc. |
Sestavek in metoda za zdravljenje diabetesa
|
US9006288B2
(en)
|
2009-01-12 |
2015-04-14 |
Biokier, Inc. |
Composition and method for treatment of diabetes
|
US9314444B2
(en)
*
|
2009-01-12 |
2016-04-19 |
Biokier, Inc. |
Composition and method for treatment of NASH
|
WO2010081488A1
(en)
*
|
2009-01-15 |
2010-07-22 |
Humanitas Mirasole S.P.A. |
Nitric oxide furoxan derivative compounds endowed with antitumoral activity
|
EP2389362B1
(en)
|
2009-01-21 |
2019-12-11 |
Oryzon Genomics, S.A. |
Phenylcyclopropylamine derivatives and their medical use
|
US20100204329A1
(en)
*
|
2009-02-06 |
2010-08-12 |
Mcfaul William J |
Method of using and establishing an absorption rate level and a neuron firing level
|
WO2010093601A1
(en)
*
|
2009-02-10 |
2010-08-19 |
Metabasis Therapeutics, Inc. |
Novel sulfonic acid-containing thyromimetics, and methods for their use
|
ES2345241B1
(es)
|
2009-03-16 |
2011-09-08 |
Lipopharma Therapeutics |
Uso de 2-hidroxiderivados de acidos grasos poliinsaturados como medicamentos.
|
AU2010229144B2
(en)
*
|
2009-03-23 |
2012-07-12 |
Merck Sharp & Dohme Corp. |
P2X3, receptor antagonists for treatment of pain
|
US8946204B2
(en)
|
2009-05-07 |
2015-02-03 |
Gruenenthal Gmbh |
Substituted phenylureas and phenylamides as vanilloid receptor ligands
|
WO2010127856A1
(en)
*
|
2009-05-07 |
2010-11-11 |
Grünenthal GmbH |
Substituted phenyllureas and phenylamides as vanilloid receptor ligands
|
KR101991367B1
(ko)
|
2009-05-13 |
2019-06-21 |
사이덱스 파마슈티칼스, 인크. |
프라수그렐 및 사이클로덱스트린 유도체를 포함하는 약학 조성물 및 그의 제조 및 사용 방법
|
CA2765086C
(en)
*
|
2009-06-12 |
2015-12-15 |
United Therapeutics Corporation |
Iminosugars and methods of treating bunyaviral and togaviral diseases
|
US8283372B2
(en)
|
2009-07-02 |
2012-10-09 |
Tetralogic Pharmaceuticals Corp. |
2-(1H-indol-3-ylmethyl)-pyrrolidine dimer as a SMAC mimetic
|
EA201290073A1
(ru)
*
|
2009-08-24 |
2013-01-30 |
Эсэпиен Фармасьютикалз, Инк. |
Соединения мочевины, содержащие 5,6-бициклический гетероарил, как ингибиторы киназ
|
WO2011032320A1
(en)
*
|
2009-09-21 |
2011-03-24 |
F. Hoffmann-La Roche Ag |
Novel alkene oxindole derivatives
|
CA2772188A1
(en)
*
|
2009-09-23 |
2011-03-31 |
Pfizer Inc. |
Gpr 119 modulators
|
WO2011035941A1
(en)
|
2009-09-25 |
2011-03-31 |
Oryzon Genomics S.A. |
Lysine specific demethylase-1 inhibitors and their use
|
EP2486002B1
(en)
|
2009-10-09 |
2019-03-27 |
Oryzon Genomics, S.A. |
Substituted heteroaryl- and aryl- cyclopropylamine acetamides and their use
|
NZ599298A
(en)
|
2009-11-27 |
2014-11-28 |
Boehringer Ingelheim Int |
Treatment of genotyped diabetic patients with dpp-iv inhibitors such as linagliptin
|
EP2528601A1
(en)
*
|
2010-01-26 |
2012-12-05 |
Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. |
Compositions and methods for prevention and treatment of pulmonary hypertension
|
EP2353591A1
(en)
|
2010-02-04 |
2011-08-10 |
Laboratorios Del. Dr. Esteve, S.A. |
Sigma ligands for potentiating the analgesic effect of opioids and opiates in post-operative pain and attenuating the dependency thereof
|
US8563610B2
(en)
*
|
2010-02-04 |
2013-10-22 |
Rutgers, The State of New Jersey |
Polyunsaturated fatty acids interactions and oxidative stress disorders
|
JP2013519685A
(ja)
*
|
2010-02-11 |
2013-05-30 |
ヴァンダービルト ユニバーシティー |
mGluR4アロステリック増強剤としてのベンズイソオキサゾール類およびアザベンズイソオキサゾール類、組成物、および神経機能不全を治療する方法
|
EP2534150B1
(en)
|
2010-02-12 |
2017-04-05 |
Chimerix, Inc. |
Methods of treating viral infection
|
WO2011106106A2
(en)
|
2010-02-24 |
2011-09-01 |
Oryzon Genomics, S.A. |
Lysine demethylase inhibitors for diseases and disorders associated with hepadnaviridae
|
US9616058B2
(en)
|
2010-02-24 |
2017-04-11 |
Oryzon Genomics, S.A. |
Potent selective LSD1 inhibitors and dual LSD1/MAO-B inhibitors for antiviral use
|
EP2544673B1
(en)
|
2010-03-08 |
2019-02-20 |
Spectrum Pharmaceuticals, Inc. |
Thioxanthone-based autophagy inhibitor therapies to treat cancer
|
CN102947265B
(zh)
*
|
2010-04-19 |
2015-07-29 |
奥瑞泽恩基因组学股份有限公司 |
赖氨酸特异性脱甲基酶-1抑制剂及其应用
|
US20130231360A1
(en)
*
|
2010-04-22 |
2013-09-05 |
The Brigham And Women S Hospital, Inc. |
Beta-Carbolines as Inhibitors of Haspin and DYRK Kinases
|
AU2011248620B2
(en)
|
2010-04-26 |
2015-11-26 |
Chimerix, Inc. |
Methods of treating retroviral infections and related dosage regimes
|
US20130035332A1
(en)
*
|
2010-04-29 |
2013-02-07 |
Layton Mark E |
Substituted 1,3-Benzothiazol-2(3H)-Ones and [1,3]Thiazolo[5,4-B]Pyridin-2(IH)-Ones as Positive Allosteric Modulators of MGLUR2
|
JP6034781B2
(ja)
|
2010-05-05 |
2016-11-30 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
併用療法
|
GB201008005D0
(en)
*
|
2010-05-13 |
2010-06-30 |
Sentinel Oncology Ltd |
Pharmaceutical compounds
|
US8785680B2
(en)
*
|
2010-05-14 |
2014-07-22 |
Agency For Science, Technology And Research |
Antimicrobial compounds and uses thereof
|
EP2388005A1
(en)
|
2010-05-21 |
2011-11-23 |
Laboratorios Del. Dr. Esteve, S.A. |
Sigma ligands for the prevention and/or treatment of emesis induced by chemotherapy or radiotherapy
|
SG185643A1
(en)
|
2010-05-27 |
2012-12-28 |
Targacept Inc |
Nicotinic receptor non-competitive antagonists
|
GB201010359D0
(en)
*
|
2010-06-21 |
2010-08-04 |
Univ Nottingham |
Compounds for treating proliferative disorders
|
AU2011270701B2
(en)
*
|
2010-06-24 |
2015-05-14 |
Alkermes Pharma Ireland Limited |
Prodrugs of NH-acidic compounds: ester, carbonate, carbamate and phosphonate derivatives
|
EP3725325B1
(en)
|
2010-06-24 |
2023-05-31 |
Boehringer Ingelheim International GmbH |
Diabetes therapy
|
TW201204733A
(en)
*
|
2010-06-25 |
2012-02-01 |
Kowa Co |
Novel condensed pyridine or condensed pyrimidine derivative, and medicinal agent comprising same
|
US8846671B2
(en)
*
|
2010-07-01 |
2014-09-30 |
Guangzhou Institute Of Biomedicine And Health, Chinese Academy Of Sciences |
Heterocyclic alkynyl benzene compounds and medical compositions and uses thereof
|
CA2805015A1
(en)
*
|
2010-07-13 |
2012-01-19 |
Stuart Ince |
Bicyclic pyrimidines
|
CA2806655A1
(en)
|
2010-07-28 |
2012-02-02 |
Bayer Intellectual Property Gmbh |
Substituted imidazo[1,2-b]pyridazines
|
SI2599774T1
(sl)
*
|
2010-07-29 |
2017-03-31 |
Astellas Pharma Inc. |
Zgoščene piridinske spojine kot CB2 kanabinoidni receptorski ligandi
|
US9006449B2
(en)
|
2010-07-29 |
2015-04-14 |
Oryzon Genomics, S.A. |
Cyclopropylamine derivatives useful as LSD1 inhibitors
|
CN103124724B
(zh)
|
2010-07-29 |
2015-05-20 |
奥瑞泽恩基因组学股份有限公司 |
Lsd1的基于芳基环丙胺的脱甲基酶抑制剂及其医疗用途
|
EP2415471A1
(en)
|
2010-08-03 |
2012-02-08 |
Laboratorios Del. Dr. Esteve, S.A. |
Use of sigma ligands in opioid-induced hyperalgesia
|
PL392436A1
(pl)
*
|
2010-09-17 |
2012-03-26 |
Adamed Spółka Z Ograniczoną Odpowiedzialnością |
Pochodne arylosulfonamidów do leczenia chorób odśrodkowego układu nerwowego
|
JP2013538784A
(ja)
*
|
2010-10-01 |
2013-10-17 |
ラクオリア創薬株式会社 |
Trpm8拮抗剤としてのスルファモイル安息香酸ヘテロ二環性誘導体
|
WO2012045883A1
(en)
|
2010-10-08 |
2012-04-12 |
Oryzon Genomics S.A. |
Cyclopropylamine inhibitors of oxidases
|
CA2815055A1
(en)
*
|
2010-10-20 |
2012-04-26 |
Biota Scientific Management Pty Ltd |
Viral polymerase inhibitors
|
TWI537258B
(zh)
|
2010-11-05 |
2016-06-11 |
百靈佳殷格翰國際股份有限公司 |
六氫茚并吡啶及八氫苯并喹啉之芳基-及雜環芳基羰基衍生物
|
US9034883B2
(en)
|
2010-11-15 |
2015-05-19 |
Boehringer Ingelheim International Gmbh |
Vasoprotective and cardioprotective antidiabetic therapy
|
ES2594404T3
(es)
*
|
2010-11-24 |
2016-12-20 |
Merck Patent Gmbh |
Quinazolincarboxamida azetidinas
|
WO2012072713A2
(en)
|
2010-11-30 |
2012-06-07 |
Oryzon Genomics, S.A. |
Lysine demethylase inhibitors for diseases and disorders associated with flaviviridae
|
US9096504B2
(en)
*
|
2010-12-01 |
2015-08-04 |
Washington State University |
Controlled chemical release of hydrogen sulfide
|
PT2661266T
(pt)
|
2011-01-07 |
2020-11-30 |
Anji Pharma Us Llc |
Terapias com base em ligandos do recetor quimiossensorial
|
US9572784B2
(en)
|
2011-01-07 |
2017-02-21 |
Elcelyx Therapeutics, Inc. |
Compositions comprising statins, biguanides and further agents for reducing cardiometabolic risk
|
US11759441B2
(en)
|
2011-01-07 |
2023-09-19 |
Anji Pharmaceuticals Inc. |
Biguanide compositions and methods of treating metabolic disorders
|
US8796338B2
(en)
|
2011-01-07 |
2014-08-05 |
Elcelyx Therapeutics, Inc |
Biguanide compositions and methods of treating metabolic disorders
|
US9480663B2
(en)
|
2011-01-07 |
2016-11-01 |
Elcelyx Therapeutics, Inc. |
Biguanide compositions and methods of treating metabolic disorders
|
US9211263B2
(en)
|
2012-01-06 |
2015-12-15 |
Elcelyx Therapeutics, Inc. |
Compositions and methods of treating metabolic disorders
|
WO2013103919A2
(en)
|
2012-01-06 |
2013-07-11 |
Elcelyx Therapeutics, Inc. |
Compositions and methods for treating metabolic disorders
|
US9050347B2
(en)
*
|
2011-01-25 |
2015-06-09 |
Viviabiotech, S.L. |
1,2,4-oxadiazole derivatives as drugs modulating the GLP-1 peptide receptor
|
WO2012107498A1
(en)
|
2011-02-08 |
2012-08-16 |
Oryzon Genomics S.A. |
Lysine demethylase inhibitors for myeloproliferative disorders
|
US20120208872A1
(en)
*
|
2011-02-11 |
2012-08-16 |
Taipei Medical University |
Use of tea polyphenols for treating and/or preventing nicotine or nicotine-derived compounds or estrogen induced breast cancer
|
KR20150075120A
(ko)
*
|
2011-02-25 |
2015-07-02 |
머크 샤프 앤드 돔 코포레이션 |
항당뇨병제로서 유용한 신규 시클릭 아자벤즈이미다졸 유도체
|
US8642655B2
(en)
*
|
2011-03-09 |
2014-02-04 |
Benjamin Johnson |
Systems and methods for preventing cancer and treating skin lesions
|
CN103596431B
(zh)
*
|
2011-03-18 |
2016-06-22 |
科赛普特治疗公司 |
嘧啶环己基糖皮质激素受体调节剂
|
US9018257B2
(en)
*
|
2011-03-24 |
2015-04-28 |
Bar Ilan University |
5-aminolevulinic acid derivatives, methods for their preparation and uses thereof
|
US8791112B2
(en)
*
|
2011-03-30 |
2014-07-29 |
Arrien Pharmaceuticals Llc |
Substituted 5-(pyrazin-2-yl)-1H-pyrazolo [3, 4-B] pyridine and pyrazolo [3, 4-B] pyridine derivatives as protein kinase inhibitors
|
AU2012242565B2
(en)
|
2011-04-13 |
2017-05-11 |
Thermolife International, Llc |
N-Acetyl Beta Alanine methods of use
|
WO2012144478A1
(ja)
*
|
2011-04-19 |
2012-10-26 |
第一三共株式会社 |
テトラヒドロチアゼピン誘導体
|
US10457659B2
(en)
|
2011-04-29 |
2019-10-29 |
The Board Of Trustees Of The Leland Stanford Junior University |
Compositions and methods for increasing proliferation of adult salivary stem cells
|
EP2524694A1
(en)
*
|
2011-05-19 |
2012-11-21 |
Laboratorios Del. Dr. Esteve, S.A. |
Use of sigma ligands in diabetes type-2 associated pain
|
US8487008B2
(en)
*
|
2011-06-22 |
2013-07-16 |
Universita Degli Studi Di Padova |
Treatment of muscular dystrophies and associated conditions by administration of monoamine oxidase inhibitors
|
WO2012177263A1
(en)
*
|
2011-06-24 |
2012-12-27 |
Intra-Cellular Therapies, Inc. |
Compounds and methods of prophylaxis and treatment regarding nictonic receptor antagonists
|
US8658677B2
(en)
*
|
2011-07-07 |
2014-02-25 |
Aria Neurosciences Inc. |
Pyridyl-2-methylamino compounds, compositions and uses thereof
|
DK2731947T3
(en)
|
2011-07-15 |
2019-04-23 |
Boehringer Ingelheim Int |
SUBSTITUTED DIMERIC QUINAZOLINE DERIVATIVE, PREPARATION AND USE thereof IN PHARMACEUTICAL COMPOSITIONS FOR TREATMENT OF TYPE I AND TYPE II DIABETES
|
TW201311679A
(zh)
*
|
2011-08-04 |
2013-03-16 |
Takeda Pharmaceutical |
含氮雜環化合物
|
UA113291C2
(xx)
|
2011-08-04 |
2017-01-10 |
|
Метаболіти транскломіфену і їх застосування
|
US9040567B2
(en)
*
|
2011-08-19 |
2015-05-26 |
Emory University |
BAX agonist, compositions, and methods related thereto
|
MY184882A
(en)
|
2011-09-14 |
2021-04-29 |
Samumed Llc |
Indazole-3-carboxamides and their use as wnt/b-catenin signaling pathyway inhibitors
|
TWI568735B
(zh)
*
|
2011-09-14 |
2017-02-01 |
吉斯藥品公司 |
新穎化合物
|
JP2014530198A
(ja)
*
|
2011-09-26 |
2014-11-17 |
グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング |
バニロイド受容体リガンドとしてのアミン置換メタンスルホンアミド誘導体
|
JP2014531451A
(ja)
|
2011-09-26 |
2014-11-27 |
グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング |
バニロイド受容体リガンドとしてのアリールまたはn−ヘテロアリール置換メタンスルホンアミド誘導体
|
RU2681211C2
(ru)
|
2011-10-20 |
2019-03-05 |
Оризон Дженомикс С.А. |
(гетеро)арилциклопропиламины в качестве ингибиторов lsd1
|
EP4074695A1
(en)
|
2011-10-20 |
2022-10-19 |
Oryzon Genomics, S.A. |
(hetero)aryl cyclopropylamine compounds as lsd1 inhibitors
|
US8816083B2
(en)
|
2011-10-26 |
2014-08-26 |
Kempharm, Inc. |
Benzoic acid, benzoic acid derivatives and heteroaryl carboxylic acid conjugates of hydromorphone, prodrugs, methods of making and use thereof
|
JP6563193B2
(ja)
*
|
2011-11-13 |
2019-08-21 |
ブランシェット・ロックフェラー・ニューロサイエンスィズ・インスティテュート |
Dcplaのエステル、およびそれを用いた処置の方法
|
EP2782994B1
(en)
|
2011-11-22 |
2017-05-10 |
Trustees Of Tufts College |
Small molecule enhancer for dendritic cell cancer vaccines
|
US20140364445A1
(en)
*
|
2011-12-05 |
2014-12-11 |
Glenmark Pharmaceuticals S.A. |
Pharmaceutical composition comprising a trpa1 antagonist and an anticholinergic agent
|
ES2832773T3
(es)
|
2012-01-06 |
2021-06-11 |
Anji Pharma Us Llc |
Composiciones de biguanida y métodos de tratamiento de trastornos metabólicos
|
CN102603493B
(zh)
*
|
2012-01-17 |
2014-03-12 |
青岛农业大学 |
含氟邻烯丙基苯酚类化合物的制备方法及农用生物活性
|
EP3300725A3
(en)
*
|
2012-02-14 |
2018-05-16 |
Repros Therapeutics Inc. |
Selective estrogen receptor modulators with short half-lives and uses thereof
|
CN102614177B
(zh)
*
|
2012-03-06 |
2014-08-06 |
北京伟峰益民科技有限公司 |
卢帕他定在制备治疗慢性阻塞性肺病药物组合物中的应用
|
US9555001B2
(en)
|
2012-03-07 |
2017-01-31 |
Boehringer Ingelheim International Gmbh |
Pharmaceutical composition and uses thereof
|
EP2830613B1
(en)
*
|
2012-03-30 |
2016-04-27 |
Nestec S.A. |
4-oxo-2-pentenoic acid and cardiovascular health
|
US9499484B2
(en)
*
|
2012-04-02 |
2016-11-22 |
Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd |
Indole, indoline derivatives, compositions comprising them and uses thereof
|
US8835494B2
(en)
*
|
2012-04-04 |
2014-09-16 |
Chiesi Farmaceutici S.P.A. |
Derivatives of 1-(2-halo-biphenyl-4-yl)-Alkanecarboxylic for the treatment of neurodegenerative diseases
|
PH12017500997A1
(en)
|
2012-04-04 |
2018-02-19 |
Samumed Llc |
Indazole inhibitors of the wnt signal pathway and therapeutic uses thereof
|
US8809376B2
(en)
*
|
2012-04-30 |
2014-08-19 |
Boehringer Ingelheim International Gmbh |
Indanyloxydihydrobenzofuranylacetic acids
|
EP2849755A1
(en)
|
2012-05-14 |
2015-03-25 |
Boehringer Ingelheim International GmbH |
A xanthine derivative as dpp -4 inhibitor for use in the treatment of podocytes related disorders and/or nephrotic syndrome
|
WO2013174767A1
(en)
|
2012-05-24 |
2013-11-28 |
Boehringer Ingelheim International Gmbh |
A xanthine derivative as dpp -4 inhibitor for use in modifying food intake and regulating food preference
|
US8859774B2
(en)
|
2012-05-25 |
2014-10-14 |
Corcept Therapeutics, Inc. |
Heteroaryl-ketone fused azadecalin glucocorticoid receptor modulators
|
WO2013192350A1
(en)
*
|
2012-06-20 |
2013-12-27 |
Vanderbilt University |
Substituted bicyclic aralkyl pyrazole lactam analogs as allosteric modulators of mglur5 receptors
|
BR112014031896A2
(pt)
*
|
2012-06-20 |
2017-06-27 |
Univ Vanderbilt |
composto, composição farmacêutica, e, método para o tratamento de um distúrbio
|
CA2879431A1
(en)
|
2012-07-17 |
2014-01-23 |
Washington University |
Anti-mucus drugs and uses therefor
|
ES2765573T3
(es)
|
2012-08-13 |
2020-06-09 |
Univ Rockefeller |
Tratamiento y diagnóstico de melanoma
|
CN104736202B
(zh)
|
2012-08-22 |
2021-09-07 |
康奈尔大学 |
用于抑制肌成束蛋白的方法
|
EP2890380A2
(en)
*
|
2012-08-29 |
2015-07-08 |
Merck Patent GmbH |
Ddr2 inhibitors for the treatment of osteoarthritis
|
US9278081B2
(en)
*
|
2012-10-04 |
2016-03-08 |
University Of The West Indies |
Extracts from Eucalyptus camaldulensis for the treatment of hyperglycemia and hypertension
|
US8859598B2
(en)
*
|
2012-10-04 |
2014-10-14 |
Allergan, Inc. |
1, 2, 4-oxadiazoles azetidine derivatives as sphingosine-1 phosphate receptors modulators
|
WO2014070523A1
(en)
|
2012-11-02 |
2014-05-08 |
Repros Therapeutics Inc. |
Trans-clomiphene for use in cancer therapy
|
US9624214B2
(en)
|
2012-11-05 |
2017-04-18 |
Bayer Pharma Aktiengesellschaft |
Amino-substituted imidazo[1,2-a]pyridinecarboxamides and their use
|
EP2922548A4
(en)
*
|
2012-11-21 |
2016-06-01 |
Stategics Inc |
SUBSTITUTED TRIAZOLO-PYRIMIDINE COMPOUNDS FOR MODULATING CELL PROPOLATION, DIFFERENTIATION AND OVER LIVING
|
EP2928879B1
(en)
*
|
2012-12-05 |
2018-02-28 |
Chiesi Farmaceutici S.p.A. |
Phenylethylpyridine derivatives as pde4-inhibitors and muscarinic receptor antagonists
|
JP6283862B2
(ja)
|
2012-12-07 |
2018-02-28 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
新規インダニルオキシジヒドロベンゾフラニル酢酸
|
UY35212A
(es)
|
2012-12-21 |
2014-06-30 |
Gilead Sciences Inc |
Inhibidores de la quinasa que regula la señal de la apoptosis
|
JP6355648B2
(ja)
|
2013-01-08 |
2018-07-11 |
サミュメッド リミテッド ライアビリティ カンパニー |
Wntシグナル伝達経路の3−(ベンゾイミダゾール−2−イル)−インダゾール阻害剤およびそれらの治療的使用
|
CU20130027A7
(es)
*
|
2013-02-28 |
2014-10-30 |
Ct De Neurociencias De Cuba |
Chaperoninas químicas como nuevos moduladores moleculares de la beta agregación proteica presente en las enfermedades conformacionales
|
EP2970181B1
(en)
|
2013-03-14 |
2017-06-07 |
Epizyme, Inc. |
Arginine methyltransferase inhibitors and uses thereof
|
EP2970133B1
(en)
|
2013-03-14 |
2018-10-24 |
Epizyme, Inc. |
Pyrazole derivatives as prmt1 inhibitors and uses thereof
|
KR20150135332A
(ko)
|
2013-03-14 |
2015-12-02 |
더 보드 오브 트러스티스 오브 더 리랜드 스탠포드 쥬니어 유니버시티 |
미토콘드리아 알데히드 탈수소효소-2 조절인자들 및 이들의 사용 방법
|
WO2014153214A1
(en)
|
2013-03-14 |
2014-09-25 |
Epizyme, Inc. |
Arginine methyl transferase inhibtors and uses thereof
|
WO2014153235A2
(en)
|
2013-03-14 |
2014-09-25 |
Epizyme, Inc. |
Arginine methyltransferase inhibitors and uses thereof
|
US9776972B2
(en)
|
2013-03-14 |
2017-10-03 |
Epizyme Inc. |
Pyrazole derivatives as arginine methyltransferase inhibitors and uses thereof
|
EP2970135B1
(en)
|
2013-03-14 |
2018-07-18 |
Epizyme, Inc. |
Pyrazole derivatives as prmt1 inhibitors and uses thereof
|
US9120757B2
(en)
|
2013-03-14 |
2015-09-01 |
Epizyme, Inc. |
Arginine methyltransferase inhibitors and uses thereof
|
SG11201506972PA
(en)
|
2013-03-14 |
2015-10-29 |
Epizyme Inc |
Arginine methyltransferase inhibitors and uses thereof
|
US9611259B2
(en)
|
2013-03-15 |
2017-04-04 |
Janssen Pharmaceutica Nv |
Substituted pyridine derivatives useful as C-FMS kinase inhibitors
|
US20140335079A1
(en)
*
|
2013-05-07 |
2014-11-13 |
Emory University |
Solenopsin and derivatives, therapeutic compositions, and methods related thereto
|
EP3017814B1
(en)
*
|
2013-07-03 |
2018-01-31 |
Mitsubishi-Chemical Foods Corporation |
Method for preventing and/or treating digital dermatitis
|
ES2742077T3
(es)
|
2013-07-18 |
2020-02-13 |
Novartis Ag |
Inhibidores de autotaxina que comprenden un núcleo de anillo heteroaromático de bencil-amida cíclica
|
US20150045435A1
(en)
*
|
2013-08-06 |
2015-02-12 |
Indiana University Research And Technology Corporation |
Compounds and methods for treating diabetes
|
WO2015026574A1
(en)
*
|
2013-08-20 |
2015-02-26 |
Bristol-Myers Squibb Company |
Imidazopyridazine kinase inhibitors useful to treating a disease or disorder mediated by aak1, such as alzheimer's disease, bipolar disorder, pain, schizophrenia
|
US9926275B2
(en)
*
|
2013-08-22 |
2018-03-27 |
Northeastern University |
Allosteric modulators of the cannabinoid 1 receptor
|
US9993456B2
(en)
*
|
2013-09-13 |
2018-06-12 |
The Board Of Trustees Of The University Of Arkansas |
Preparation and use of a composition for prevention and mitigation of the effects of radiation
|
US9353078B2
(en)
*
|
2013-10-01 |
2016-05-31 |
New York University |
Amino, amido and heterocyclic compounds as modulators of rage activity and uses thereof
|
EP3060257B1
(en)
*
|
2013-10-22 |
2021-02-24 |
Translate Bio, Inc. |
Lipid formulations for delivery of messenger rna
|
US9796709B2
(en)
*
|
2013-12-13 |
2017-10-24 |
Daiichi Sankyo Company, Limited |
5-hydroxy-4-(trifluoromethyl)pyrazolopyridine derivative
|
BR112016013754A2
(pt)
|
2013-12-17 |
2017-08-08 |
Esteve Labor Dr |
Recaptação de serotonina-norepinefrina inibidores (irsns) e combinações dos ligantes do receptor sigma
|
US9381171B2
(en)
*
|
2013-12-19 |
2016-07-05 |
Samsung Electronics Co., Ltd. |
Composition including dapsone for preventing or treating side effect of steroid in subject and use of the composition
|
US9862704B2
(en)
*
|
2013-12-20 |
2018-01-09 |
AbbVie Deutschland GmbH & Co. KG |
Oxindole derivatives carrying an amine-substituted piperidyl-acetidinyl substituent and use thereof for treating vasopressine-related diseases
|
CN104744446B
(zh)
*
|
2013-12-30 |
2019-06-25 |
广东东阳光药业有限公司 |
杂芳化合物及其在药物中的应用
|
EP3091970B1
(en)
|
2014-01-10 |
2020-10-28 |
Rgenix, Inc. |
Lxr agonists and uses thereof
|
US9636298B2
(en)
|
2014-01-17 |
2017-05-02 |
Methylgene Inc. |
Prodrugs of compounds that enhance antifungal activity and compositions of said prodrugs
|
US10231965B2
(en)
|
2014-02-20 |
2019-03-19 |
Ignyta, Inc. |
Molecules for administration to ROS1 mutant cancer cells
|
CN106232583B
(zh)
|
2014-02-20 |
2020-04-24 |
康奈尔大学 |
用于抑制肌成束蛋白的化合物和方法
|
JP6615109B2
(ja)
|
2014-02-28 |
2019-12-04 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
Dpp−4阻害薬の医学的使用
|
CN106715426A
(zh)
|
2014-03-21 |
2017-05-24 |
拜耳医药股份有限公司 |
氰基取代的咪唑并[1,2‑a]吡啶甲酰胺及其用途
|
US20150335668A1
(en)
|
2014-05-20 |
2015-11-26 |
Millennium Pharmaceuticals, Inc. |
Method for cancer therapy
|
MX2016014384A
(es)
|
2014-06-23 |
2017-01-20 |
Celgene Corp |
Apremilast para el tratamiento de una enfermedad del higado o una anormalidad en la funcion del higado.
|
WO2016040181A1
(en)
|
2014-09-08 |
2016-03-17 |
Samumed, Llc |
3-(1h-imidazo[4,5-c]pyridin-2-yl)-1h-pyrazolo[3,4-c]pyridine and therapeutic uses thereof
|
WO2016040180A1
(en)
|
2014-09-08 |
2016-03-17 |
Samumed, Llc |
3-(1h-benzo[d]imidazol-2-yl)-1h-pyrazolo[3,4-c]pyridine and therapeutic uses thereof
|
WO2016040185A1
(en)
|
2014-09-08 |
2016-03-17 |
Samumed, Llc |
2-(1h-indazol-3-yl)-3h-imidazo[4,5-b]pyridine and therapeutic uses thereof
|
WO2016040193A1
(en)
|
2014-09-08 |
2016-03-17 |
Samumed, Llc |
3-(1h-imidazo[4,5-c]pyridin-2-yl)-1h-pyrazolo[3,4-b]pyridine and therapeutic uses thereof
|
WO2016040190A1
(en)
|
2014-09-08 |
2016-03-17 |
Samumed, Llc |
3-(3h-imidazo[4,5-b]pyridin-2-yl)-1h-pyrazolo[3,4-b]pyridine and therapeutic uses thereof
|
WO2016040184A1
(en)
|
2014-09-08 |
2016-03-17 |
Samumed, Llc |
3-(3h-imidazo[4,5-b]pyridin-2-yl)-1h-pyrazolo[3,4-c]pyridine and therapeutic uses thereof
|
WO2016062290A1
(zh)
*
|
2014-10-24 |
2016-04-28 |
朗齐生物医学股份有限公司 |
氨苯蝶啶药物在用于制备治疗癌症的医药组合物中的用途
|
US10213445B2
(en)
*
|
2014-11-06 |
2019-02-26 |
ARIZONA BOARD OF REGENTS on behalf of THE UNIVERSITY OF ARIZONA, A BODY CORPORATE |
Compositions and methods of diazeniumdiolate-based prodrugs for treating cancer
|
WO2016073983A2
(en)
*
|
2014-11-07 |
2016-05-12 |
Northwestern University |
Ornithine aminotransferase inhibition with gaba analogues for treatment of hepatocellular carcinoma
|
AU2015355220B2
(en)
|
2014-12-02 |
2020-02-27 |
Ignyta, Inc. |
Combinations for the treatment of neuroblastoma
|
WO2016087343A1
(de)
|
2014-12-02 |
2016-06-09 |
Bayer Pharma Aktiengesellschaft |
Heteroaryl-substituierte imidazo[1,2-a]pyridine und ihre verwendung
|
US9682076B2
(en)
*
|
2014-12-02 |
2017-06-20 |
Kempharm, Inc. |
Benzoic acid, benzoic acid derivatives and heteroaryl carboxylic acid conjugates of oxymorphone, prodrugs, methods of making and use thereof
|
CN107427515B
(zh)
*
|
2014-12-03 |
2021-11-16 |
奥克兰联合服务有限公司 |
用于治疗癌症的激酶抑制剂前药
|
EP3230478B1
(en)
*
|
2014-12-12 |
2023-08-02 |
Miradx |
Methods for treating or preventing cancer in a kras-variant patient and for diagnosing risk of developing multiple primary breast tumors
|
BR112017015721A2
(pt)
|
2015-01-22 |
2018-04-10 |
Mitochon Pharmaceuticals Inc |
expressão induzida de fator neurotrófico derivado do cérebro (bdnf) para o tratamento de doenças neuromusculares, neurodegenerativas, autoimunes, do desenvolvimento e/ou metabólicas.
|
CA3213864A1
(en)
|
2015-03-04 |
2016-09-09 |
Vanda Pharmaceuticals Inc. |
Dosing regimen of tradipitant
|
EP3274053A4
(en)
|
2015-03-23 |
2018-12-05 |
The Brigham and Women's Hospital, Inc. |
Tolerogenic nanoparticles for treating diabetes mellitus
|
MX2017013142A
(es)
|
2015-04-20 |
2019-03-28 |
Epizyme Inc |
Terapia combinada para tratar cáncer.
|
JP2018514572A
(ja)
*
|
2015-04-30 |
2018-06-07 |
エムユーエスシー ファウンデーション フォー リサーチ ディベロップメント |
オキシンドール化合物およびその医薬組成物
|
US20160324914A1
(en)
|
2015-05-05 |
2016-11-10 |
Tocol Pharmaceuticals, Llc |
Use of rice bran oil distillate extract for prevention and mitigation of the effects of radiation
|
TWI713534B
(zh)
|
2015-06-11 |
2020-12-21 |
日商第一三共股份有限公司 |
5-羥基-4-(三氟甲基)吡唑并吡啶衍生物之結晶及其用途
|
GB201511382D0
(en)
|
2015-06-29 |
2015-08-12 |
Imp Innovations Ltd |
Novel compounds and their use in therapy
|
US10350199B2
(en)
|
2015-08-03 |
2019-07-16 |
Samumed, Llc |
3-(1h-pyrrolo[2,3-b]pyridin-2-yl)-1h-indazoles and therapeutic uses thereof
|
WO2017024004A1
(en)
|
2015-08-03 |
2017-02-09 |
Samumed, Llc. |
3-(1h-pyrrolo[2,3-b]pyridin-2-yl)-1h-pyrazolo[4,3-b]pyridines and therapeutic uses thereof
|
WO2017023987A1
(en)
|
2015-08-03 |
2017-02-09 |
Samumed, Llc. |
3-(1h-pyrrolo[3,2-c]pyridin-2-yl)-1h-pyrazolo[3,4-b]pyridines and therapeutic uses thereof
|
US10463651B2
(en)
|
2015-08-03 |
2019-11-05 |
Samumed, Llc |
3-(1H-pyrrolo[3,2-C]pyridin-2-YL)-1H-indazoles and therapeutic uses thereof
|
US10285983B2
(en)
|
2015-08-03 |
2019-05-14 |
Samumed, Llc |
3-(1H-pyrrolo[2,3-B]pyridin-2-yl)-1H-pyrazolo[3,4-B] pyridines and therapeutic uses thereof
|
WO2017023980A1
(en)
|
2015-08-03 |
2017-02-09 |
Samumed, Llc. |
3-(1h-pyrrolo[2,3-b]pyridin-2-yl)-1h-pyrazolo[3,4-c]pyridines and therapeutic uses thereof
|
US10392383B2
(en)
|
2015-08-03 |
2019-08-27 |
Samumed, Llc |
3-(1H-benzo[d]imidazol-2-yl)-1H-pyrazolo[4,3-b]pyridines and therapeutic uses thereof
|
WO2017023988A1
(en)
|
2015-08-03 |
2017-02-09 |
Samumed, Llc. |
3-(3h-imidazo[4,5-c]pyridin-2-yl)-1h-pyrazolo[4,3-b]pyridines and therapeutic uses thereof
|
US10195185B2
(en)
|
2015-08-03 |
2019-02-05 |
Samumed, Llc |
3-(1H-imidazo[4,5-C]pyridin-2-yl)-1H-pyrazolo[4,3-B]pyridines and therapeutic uses thereof
|
US10519169B2
(en)
|
2015-08-03 |
2019-12-31 |
Samumed, Llc |
3-(1H-pyrrolo[2,3-C]pyridin-2-yl)-1 H-pyrazolo[4,3-B]pyridines and therapeutic uses thereof
|
WO2017024026A1
(en)
|
2015-08-03 |
2017-02-09 |
Samumed, Llc |
3-(1h-indol-2-yl)-1h-pyrazolo[3,4-c]pyridines and therapeutic uses thereof
|
US10383861B2
(en)
|
2015-08-03 |
2019-08-20 |
Sammumed, LLC |
3-(1H-pyrrolo[2,3-C]pyridin-2-yl)-1H-pyrazolo[3,4-C]pyridines and therapeutic uses thereof
|
WO2017024015A1
(en)
*
|
2015-08-03 |
2017-02-09 |
Samumed, Llc. |
3-(3h-imidazo[4,5-b]pyridin-2-yl)-1h-pyrazolo[4,3-b]pyridines and therapeutic uses thereof
|
WO2017023984A1
(en)
|
2015-08-03 |
2017-02-09 |
Samumed, Llc. |
3-(1h-pyrrolo[3,2-c]pyridin-2-yl)-1h-pyrazolo[3,4-c]pyridines and therapeutic uses thereof
|
US10604512B2
(en)
|
2015-08-03 |
2020-03-31 |
Samumed, Llc |
3-(1H-indol-2-yl)-1H-indazoles and therapeutic uses thereof
|
US10231956B2
(en)
|
2015-08-03 |
2019-03-19 |
Samumed, Llc |
3-(1H-pyrrolo[3,2-C]pyridin-2-YL)-1 H-pyrazolo[4,3-B]pyridines and therapeutic uses thereof
|
WO2017023993A1
(en)
|
2015-08-03 |
2017-02-09 |
Samumed, Llc. |
3-(1h-indol-2-yl)-1h-pyrazolo[4,3-b]pyridines and therapeutic uses thereof
|
US9675608B2
(en)
*
|
2015-08-26 |
2017-06-13 |
Macau University Of Science And Technology |
Identification of natural small-molecules AMPK activators for treatment of cancers or multidrug-resistant cancers
|
KR20180061363A
(ko)
*
|
2015-10-08 |
2018-06-07 |
쑤저우 운씨엔 이야오 커지 요씨엔 공시 |
Wnt 신호 전달 경로 억제제 및 이의 치료적 적용
|
GB201519450D0
(en)
*
|
2015-11-03 |
2015-12-16 |
Univ Liverpool |
Novel treatment
|
WO2017079765A1
(en)
|
2015-11-06 |
2017-05-11 |
Samumed, Llc |
Treatment of osteoarthritis
|
US9549907B1
(en)
*
|
2015-11-13 |
2017-01-24 |
Sovereign Pharmaceuticals, Llc |
Immediate release oral guaifenesin solution
|
US10765665B2
(en)
*
|
2015-11-24 |
2020-09-08 |
Melin Jeffrey |
Composition comprising combination of rapamycin and an activator of AMP kinase and use thereof for treating diseases
|
CN115806550A
(zh)
*
|
2015-11-25 |
2023-03-17 |
康威基内有限公司 |
双环bet布罗莫结构域抑制剂及其用途
|
MX2018007266A
(es)
|
2015-12-18 |
2018-11-09 |
Ignyta Inc |
Combinaciones para el tratamiento del cancer.
|
CN109071457A
(zh)
*
|
2016-03-09 |
2018-12-21 |
荷兰转化研究中心有限责任公司 |
吲哚胺2,3-双加氧酶的抑制剂
|
ES2814499T3
(es)
*
|
2016-03-14 |
2021-03-29 |
Pliva Hrvatska D O O |
Formas en estado sólido de sales de Nilotinib
|
US10064834B2
(en)
*
|
2016-05-09 |
2018-09-04 |
Texas Tech University System |
Carbidopa for the treatment of cancer
|
CN109562113A
(zh)
*
|
2016-05-10 |
2019-04-02 |
C4医药公司 |
用于靶蛋白降解的螺环降解决定子体
|
US20190054041A1
(en)
*
|
2016-05-26 |
2019-02-21 |
Institute Of Tropical Bioscience And Biotechology Chinese Academy Of Tropical Agricultural Sciences |
Use of nootkatone
|
EP3251668A1
(en)
|
2016-06-02 |
2017-12-06 |
Pharmotech SA |
Cannabidiol compositions and uses thereof
|
CA3022202A1
(en)
|
2016-06-10 |
2017-12-14 |
Boehringer Ingelheim International Gmbh |
Combinations of linagliptin and metformin
|
US10729670B2
(en)
|
2016-09-07 |
2020-08-04 |
Temple University—Of The Commonwealth Systems Of Higher Education |
Compositions and methods for treatment of insulin resistance
|
EP3446704A1
(en)
|
2017-08-24 |
2019-02-27 |
Isofol Medical AB |
[6r]-mthf - an efficient folate alternative in 5-fluorouracil based chemotherapy
|
EP3446703A1
(en)
*
|
2017-08-24 |
2019-02-27 |
Isofol Medical AB |
6r]-mthf multiple bolus administration in 5-fluorouracil based chemotherapy
|
EP3528808B1
(en)
|
2016-10-21 |
2021-10-06 |
BioSplice Therapeutics, Inc. |
Methods of using indazole-3-carboxamides and their use as wnt/b-catenin signaling pathway inhibitors
|
WO2018085865A1
(en)
|
2016-11-07 |
2018-05-11 |
Samumed, Llc |
Single-dose, ready-to-use injectable formulations
|
JP2020500199A
(ja)
|
2016-11-21 |
2020-01-09 |
バイキング・セラピューティクス・インコーポレイテッド |
グリコーゲン蓄積症の治療方法
|
CA3027257A1
(en)
|
2016-12-15 |
2018-06-21 |
Nestec S.A. |
Compositions and methods that modulate digestibility in a companion animal
|
US10723716B2
(en)
|
2016-12-21 |
2020-07-28 |
New York University |
Alpha-helix mimetics as modulators of Abeta self-assembly
|
EP3573953A1
(en)
|
2017-01-26 |
2019-12-04 |
Boehringer Ingelheim International GmbH |
Benzyloxypyridylcyclopropanecarboxylic acids, pharmaceutical compositions and uses thereof
|
US10603317B2
(en)
|
2017-01-26 |
2020-03-31 |
Boehringer Ingelheim International Gmbh |
Benzylaminopyridylcyclopropanecarboxylic acids, pharmaceutical compositions and uses thereof
|
EP3573952B1
(en)
|
2017-01-26 |
2021-07-14 |
Boehringer Ingelheim International GmbH |
Benzylaminopyridylcyclopropanecarboxylic acids, pharmaceuticalcompositions and uses thereof
|
US10793530B2
(en)
|
2017-01-26 |
2020-10-06 |
Boehringer Ingelheim International Gmbh |
Benzylaminopyrazinylcyclopropanecarboxylic acids, pharmaceutical compositions and uses thereof
|
JP7049353B2
(ja)
|
2017-02-08 |
2022-04-06 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
糖尿病の治療のためのインダニルアミノアザジヒドロベンゾフラニル酢酸、医薬組成物
|
SG11201907442UA
(en)
|
2017-02-14 |
2019-09-27 |
Isofol Medical Ab |
METHODS FOR INCREASING BLOOD PLASMA 2'-DEOXYURIDINE (dUrd) AND THYMIDYLATE SYNTHASE INHIBITION
|
US10517842B2
(en)
*
|
2017-03-15 |
2019-12-31 |
Los Angeles Biomedical Research Institute At Harbor-Ucla Medical Center |
Methods of modulating miRNA levels and compositions for use in the same
|
RU2019129299A
(ru)
|
2017-03-31 |
2021-04-30 |
Корсепт Терапьютикс, Инк. |
Модуляторы глюкокортикоидного рецептора для лечения рака шейки матки
|
RU2675496C1
(ru)
*
|
2017-03-31 |
2018-12-20 |
Федеральное государственное бюджетное учреждение науки Институт нефтехимии и катализа Российской академии наук |
Способ получения алкиловых эфиров гидроксибензойных кислот
|
US20180280319A1
(en)
*
|
2017-04-04 |
2018-10-04 |
University Of The Sciences |
Compounds and compositions for treatment of breast cancer
|
FR3066393B1
(fr)
*
|
2017-05-16 |
2019-07-19 |
Polyneuros |
Principe actif constitue par un melange de composes poly-lysine et utilisation dans la prevention des avc et le traitement de la phase inflammatoire post-avc
|
US11491150B2
(en)
|
2017-05-22 |
2022-11-08 |
Intra-Cellular Therapies, Inc. |
Organic compounds
|
WO2018226604A1
(en)
|
2017-06-05 |
2018-12-13 |
Viking Therapeutics, Inc. |
Compositions for the treatment of fibrosis
|
WO2019018570A1
(en)
*
|
2017-07-19 |
2019-01-24 |
Ignyta, Inc. |
PHARMACEUTICAL COMPOSITIONS CONTAINING ENTRECTINIB
|
US10639313B2
(en)
*
|
2017-09-01 |
2020-05-05 |
Ndsu Research Foundation |
Compound for inhibition of delta-5-desaturase (D5D) and treatment of cancer and inflammation
|
US11549147B2
(en)
|
2017-09-13 |
2023-01-10 |
Vanda Pharmaceuticals Inc. |
Treatment of atopic dermatitis with tradipitant
|
US10342786B2
(en)
|
2017-10-05 |
2019-07-09 |
Fulcrum Therapeutics, Inc. |
P38 kinase inhibitors reduce DUX4 and downstream gene expression for the treatment of FSHD
|
CN114732910A
(zh)
|
2017-10-05 |
2022-07-12 |
弗尔康医疗公司 |
P38激酶抑制剂降低dux4和下游基因表达以用于治疗fshd
|
EP3697390A1
(en)
|
2017-10-17 |
2020-08-26 |
Ignyta, Inc. |
Pharmaceutical compositions and dosage forms
|
WO2019084323A1
(en)
*
|
2017-10-25 |
2019-05-02 |
Georgia State University Research Foundation, Inc. |
CHEMICAL RELEASE SYSTEM DELIVERED BY ENRICHMENT
|
EP3710431A4
(en)
|
2017-11-03 |
2021-07-07 |
Aclaris Therapeutics, Inc. |
SUBSTITUTED PYRROLOPYRIMIDINE JAK INHIBITORS AND METHODS FOR THEIR MANUFACTURE AND USE
|
CA3078981A1
(en)
|
2017-11-21 |
2019-05-31 |
Rgenix, Inc. |
Polymorphs and uses thereof
|
US11787828B2
(en)
|
2018-03-22 |
2023-10-17 |
Viking Therapeutics, Inc. |
Crystalline forms and methods of producing crystalline forms of a compound
|
CA3094324A1
(en)
|
2018-03-26 |
2019-10-03 |
Clear Creek Bio, Inc. |
Compositions and methods for inhibiting dihydroorotate dehydrogenase
|
SG11202011948SA
(en)
|
2018-06-04 |
2020-12-30 |
Corcept Therapeutics Inc |
Pyrimidine cyclohexenyl glucocorticoid receptor modulators
|
CN112823005A
(zh)
|
2018-08-10 |
2021-05-18 |
阿克拉瑞斯治疗股份有限公司 |
吡咯并嘧啶itk抑制剂
|
US11234971B2
(en)
|
2018-12-19 |
2022-02-01 |
Corcept Therapeutics Incorporated |
Methods of treating cancer comprising administration of a glucocorticoid receptor modulator and a cancer chemotherapy agent
|
SG11202105770YA
(en)
|
2018-12-19 |
2021-07-29 |
Corcept Therapeutics Inc |
Pharmaceutical formulations containing relacorilant, a heteroaryl-ketone fused azadecalin compound
|
WO2020132046A1
(en)
|
2018-12-19 |
2020-06-25 |
Corcept Therapeutics Incorporated |
Methods of treating cancer comprising administration of a glucocorticoid receptor modulator and a cancer chemotherapy agent
|
KR20220004726A
(ko)
|
2019-05-02 |
2022-01-11 |
어클라리스 쎄라퓨틱스, 인코포레이티드 |
Jak 억제제로서의 치환된 피롤로피리딘
|
JP2023505948A
(ja)
|
2019-12-11 |
2023-02-14 |
コーセプト セラピューティクス, インコーポレイテッド |
抗精神病薬誘発性体重増加のミリコリラントによる治療方法
|
WO2021119397A1
(en)
|
2019-12-13 |
2021-06-17 |
Rgenix, Inc. |
Metal salts and uses thereof
|
CN115551836A
(zh)
|
2020-05-06 |
2022-12-30 |
科赛普特治疗公司 |
嘧啶环己基糖皮质激素受体调节剂的多晶型物
|
US11071739B1
(en)
|
2020-09-29 |
2021-07-27 |
Genus Lifesciences Inc. |
Oral liquid compositions including chlorpromazine
|
US11865139B2
(en)
|
2020-11-12 |
2024-01-09 |
Thermolife International, Llc |
Method of treating migraines and headaches
|
AU2021409656A1
(en)
|
2020-12-21 |
2023-07-06 |
Corcept Therapeutics Incorporated |
Method of preparing pyrimidine cyclohexyl glucocorticoid receptor modulators
|
CN113354558B
(zh)
*
|
2021-07-12 |
2022-03-11 |
无锡双启科技有限公司 |
一种2-氨基-5-氟苯腈的制备方法
|