BG63991B1 - Фармацевтично средство, съдържащо rно киназен инхибитор - Google Patents
Фармацевтично средство, съдържащо rно киназен инхибитор Download PDFInfo
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- BG63991B1 BG63991B1 BG103246A BG10324699A BG63991B1 BG 63991 B1 BG63991 B1 BG 63991B1 BG 103246 A BG103246 A BG 103246A BG 10324699 A BG10324699 A BG 10324699A BG 63991 B1 BG63991 B1 BG 63991B1
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- compound
- formula
- pharmaceutically acceptable
- isomer
- alkyl
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- 229920002554 vinyl polymer Polymers 0.000 description 1
- 239000001993 wax Substances 0.000 description 1
- 239000003871 white petrolatum Substances 0.000 description 1
- 229910000166 zirconium phosphate Inorganic materials 0.000 description 1
Classifications
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
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- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Oncology (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Transplantation (AREA)
- Communicable Diseases (AREA)
- Vascular Medicine (AREA)
- Ophthalmology & Optometry (AREA)
- AIDS & HIV (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyridine Compounds (AREA)
- Materials Applied To Surfaces To Minimize Adherence Of Mist Or Water (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP21240996 | 1996-08-12 | ||
PCT/JP1997/002793 WO1998006433A1 (en) | 1996-08-12 | 1997-08-08 | MEDICINES COMPRISING Rho KINASE INHIBITOR |
Publications (2)
Publication Number | Publication Date |
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BG103246A BG103246A (en) | 2000-05-31 |
BG63991B1 true BG63991B1 (bg) | 2003-09-30 |
Family
ID=16622116
Family Applications (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BG107195/2002A BG63992B1 (bg) | 1996-08-12 | 1999-03-12 | Амидно съединение и приложение му като rho киназен инхибитор |
BG103246A BG63991B1 (bg) | 1996-08-12 | 1999-03-12 | Фармацевтично средство, съдържащо rно киназен инхибитор |
BG107195/2002A BG107195A (en) | 1996-08-12 | 1999-03-12 | AMIDE COMPOUND AND ITS APPLICATION AS Rho KINASE INHIBITOR |
BG107645/2003A BG107645A (en) | 1996-08-12 | 2003-03-19 | MEDICINES COMPRISING Rho KINASE INHIBITOR |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
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BG107195/2002A BG63992B1 (bg) | 1996-08-12 | 1999-03-12 | Амидно съединение и приложение му като rho киназен инхибитор |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
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BG107195/2002A BG107195A (en) | 1996-08-12 | 1999-03-12 | AMIDE COMPOUND AND ITS APPLICATION AS Rho KINASE INHIBITOR |
BG107645/2003A BG107645A (en) | 1996-08-12 | 2003-03-19 | MEDICINES COMPRISING Rho KINASE INHIBITOR |
Country Status (25)
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US (3) | US6218410B1 (cs) |
EP (1) | EP0956865B2 (cs) |
JP (1) | JP3669711B2 (cs) |
KR (2) | KR100595740B1 (cs) |
CN (1) | CN100389828C (cs) |
AT (1) | ATE359822T1 (cs) |
AU (1) | AU738620B2 (cs) |
BG (4) | BG63992B1 (cs) |
BR (1) | BR9711154A (cs) |
CA (1) | CA2263425C (cs) |
CZ (1) | CZ301044B6 (cs) |
DE (1) | DE69737631T3 (cs) |
DK (1) | DK0956865T4 (cs) |
EE (1) | EE9900050A (cs) |
ES (1) | ES2286834T5 (cs) |
HU (1) | HU229864B1 (cs) |
IL (1) | IL128456A0 (cs) |
IS (1) | IS4973A (cs) |
NO (1) | NO990622L (cs) |
NZ (2) | NZ513800A (cs) |
PL (1) | PL331561A1 (cs) |
PT (1) | PT956865E (cs) |
RU (3) | RU2206321C2 (cs) |
SI (1) | SI0956865T2 (cs) |
WO (1) | WO1998006433A1 (cs) |
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EP1195372A1 (en) † | 1994-04-18 | 2002-04-10 | Mitsubishi Pharma Corporation | N-heterocyclic substituted benzamide derivatives with antihypertensive activity |
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US6218410B1 (en) * | 1996-08-12 | 2001-04-17 | Yoshitomi Pharmaceutical Industries, Ltd. | Medicines comprising Rho kinase inhibitor |
-
1997
- 1997-08-08 US US09/242,261 patent/US6218410B1/en not_active Expired - Lifetime
- 1997-08-08 CN CNB971987386A patent/CN100389828C/zh not_active Expired - Lifetime
- 1997-08-08 JP JP50959298A patent/JP3669711B2/ja not_active Expired - Lifetime
- 1997-08-08 CZ CZ0046099A patent/CZ301044B6/cs not_active IP Right Cessation
- 1997-08-08 SI SI9730764T patent/SI0956865T2/sl unknown
- 1997-08-08 RU RU99104798/14A patent/RU2206321C2/ru not_active IP Right Cessation
- 1997-08-08 KR KR1020057006623A patent/KR100595740B1/ko not_active Expired - Fee Related
- 1997-08-08 AT AT97934756T patent/ATE359822T1/de active
- 1997-08-08 PT PT97934756T patent/PT956865E/pt unknown
- 1997-08-08 KR KR1019997001121A patent/KR100576148B1/ko not_active Expired - Fee Related
- 1997-08-08 NZ NZ513800A patent/NZ513800A/xx unknown
- 1997-08-08 BR BR9711154A patent/BR9711154A/pt not_active IP Right Cessation
- 1997-08-08 IL IL12845697A patent/IL128456A0/xx unknown
- 1997-08-08 EE EEP199900050A patent/EE9900050A/xx unknown
- 1997-08-08 ES ES97934756T patent/ES2286834T5/es not_active Expired - Lifetime
- 1997-08-08 DE DE69737631T patent/DE69737631T3/de not_active Expired - Lifetime
- 1997-08-08 WO PCT/JP1997/002793 patent/WO1998006433A1/ja not_active Ceased
- 1997-08-08 DK DK97934756.4T patent/DK0956865T4/da active
- 1997-08-08 NZ NZ334613A patent/NZ334613A/xx unknown
- 1997-08-08 EP EP97934756A patent/EP0956865B2/en not_active Expired - Lifetime
- 1997-08-08 CA CA002263425A patent/CA2263425C/en not_active Expired - Lifetime
- 1997-08-08 PL PL97331561A patent/PL331561A1/xx unknown
- 1997-08-08 AU AU37851/97A patent/AU738620B2/en not_active Ceased
- 1997-08-08 HU HU9903694A patent/HU229864B1/hu unknown
-
1999
- 1999-02-10 NO NO990622A patent/NO990622L/no not_active Application Discontinuation
- 1999-02-11 IS IS4973A patent/IS4973A/is unknown
- 1999-03-12 BG BG107195/2002A patent/BG63992B1/bg unknown
- 1999-03-12 BG BG103246A patent/BG63991B1/bg unknown
- 1999-03-12 BG BG107195/2002A patent/BG107195A/xx unknown
-
2001
- 2001-02-26 US US09/791,648 patent/US6451825B1/en not_active Expired - Lifetime
-
2002
- 2002-07-31 US US10/208,100 patent/US6906061B2/en not_active Expired - Fee Related
-
2003
- 2003-02-06 RU RU2003103606/15A patent/RU2003103606A/ru not_active Application Discontinuation
- 2003-02-12 RU RU2003104284/15A patent/RU2003104284A/ru not_active Application Discontinuation
- 2003-03-19 BG BG107645/2003A patent/BG107645A/xx unknown
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