|
WO2003034977A2
(en)
*
|
2001-10-26 |
2003-05-01 |
Altarex Medical Corp. |
Combination therapy for treating disease
|
|
US8038994B2
(en)
|
1996-05-15 |
2011-10-18 |
Quest Pharmatech Inc. |
Combination therapy for treating disease
|
|
US6949245B1
(en)
|
1999-06-25 |
2005-09-27 |
Genentech, Inc. |
Humanized anti-ErbB2 antibodies and treatment with anti-ErbB2 antibodies
|
|
KR20020012292A
(ko)
*
|
1999-06-25 |
2002-02-15 |
제넨테크, 인크. |
항-ErbB 항체-메이탄시노이드 결합체를 사용한 치료방법
|
|
PL203326B1
(pl)
*
|
1999-06-25 |
2009-09-30 |
Genentech Inc |
Przeciwciało, kompozycja farmaceutyczna, koniugat, izolowany kwas nukleinowy, wektor, komórka gospodarza i sposób wytwarzania przeciwciała
|
|
US6825333B1
(en)
|
1999-08-20 |
2004-11-30 |
Chiron Corporation |
EGFH2 genes and gene products
|
|
DE60042693D1
(de)
|
1999-08-27 |
2009-09-17 |
Genentech Inc |
Dosierung für die behandlung mit anti erbb2-antikörpern
|
|
WO2001024763A2
(en)
|
1999-10-01 |
2001-04-12 |
Immunogen, Inc. |
Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents
|
|
CN1447696A
(zh)
|
2000-05-19 |
2003-10-08 |
杰南技术公司 |
用于提高对ErbB拮抗剂癌症治疗的有效应答可能性的基因检测试验
|
|
EP1228766A1
(en)
*
|
2001-01-31 |
2002-08-07 |
Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. |
PYK2 phosphorylation by HER3 induces tumor invasion
|
|
PL375033A1
(en)
*
|
2002-04-11 |
2005-11-14 |
Amgen, Inc. |
Her-2 receptor tyrosine kinase molecules and uses thereof
|
|
ITTO20020340A1
(it)
*
|
2002-04-19 |
2003-10-20 |
Biother Di Contardi Gabriella |
Localizzazione del recettore her2 mediante anticorpo umanizzato biotinilato.
|
|
US7198899B2
(en)
|
2002-06-03 |
2007-04-03 |
Chiron Corporation |
Use of NRG4, or inhibitors thereof, in the treatment of colon and pancreatic cancers
|
|
AT413486B
(de)
|
2002-07-03 |
2006-03-15 |
Igeneon Krebs Immuntherapie |
Verwendung eines antikörpers gerichtet gegen lewis-antigene
|
|
NO340576B1
(no)
*
|
2002-07-11 |
2017-05-15 |
Hoffmann La Roche |
Rekombinant, humanisert antistoff 2C4 (rhuMab 2C4) for anvendelse sammen med et andre, forskjellig vekstinhiberende anti-ErbB2-antistoff i en fremgangsmåte for behandling av kreft i en pasient og anvendelse derav for fremstilling av et medikament
|
|
ATE535254T1
(de)
|
2002-07-15 |
2011-12-15 |
Genentech Inc |
Behandlung von krebs mit dem anti-erbb2- antikörper rhumab 2c4
|
|
CN105884893A
(zh)
|
2002-07-18 |
2016-08-24 |
莫鲁斯有限公司 |
抗体混合物的重组生产
|
|
US7264800B2
(en)
|
2002-07-18 |
2007-09-04 |
Helix Biopharma Corporation |
Method and composition for inhibiting cancer cell growth
|
|
USRE47770E1
(en)
|
2002-07-18 |
2019-12-17 |
Merus N.V. |
Recombinant production of mixtures of antibodies
|
|
EP1530482B9
(en)
*
|
2002-07-18 |
2014-04-16 |
Helix Biopharma Corp. |
Use of urease for inhibiting cancer cell growth
|
|
CA2494310A1
(en)
|
2002-08-01 |
2004-02-12 |
Immunomedics, Inc. |
Alpha-fetoprotein immu31 antibodies and fusion proteins and methods of use thereof
|
|
US20040033228A1
(en)
|
2002-08-16 |
2004-02-19 |
Hans-Juergen Krause |
Formulation of human antibodies for treating TNF-alpha associated disorders
|
|
WO2004032857A2
(en)
*
|
2002-10-08 |
2004-04-22 |
Immunomedics, Inc. |
Antibody therapy
|
|
JP4959136B2
(ja)
*
|
2002-12-13 |
2012-06-20 |
イミューノメディクス、インコーポレイテッド |
細胞内で開裂可能な結合を有する免疫接合体
|
|
CA2518716A1
(en)
*
|
2003-03-11 |
2005-01-13 |
Dana-Farber Cancer Institute |
Inhibition of viral pathogenesis
|
|
EP1631590B1
(en)
*
|
2003-04-23 |
2011-07-27 |
Medarex, Inc. |
Humanized antibodies to interferon alpha receptor-1 (ifnar-1)
|
|
US8088387B2
(en)
|
2003-10-10 |
2012-01-03 |
Immunogen Inc. |
Method of targeting specific cell populations using cell-binding agent maytansinoid conjugates linked via a non-cleavable linker, said conjugates, and methods of making said conjugates
|
|
AT500651B9
(de)
*
|
2003-05-27 |
2010-04-15 |
Altropus Gmbh |
Aktiv immunisierender antikörper
|
|
US20100069614A1
(en)
|
2008-06-27 |
2010-03-18 |
Merus B.V. |
Antibody producing non-human mammals
|
|
WO2004106375A1
(en)
|
2003-05-30 |
2004-12-09 |
Merus Biopharmaceuticals B.V. I.O. |
Fab library for the preparation of anti vegf and anti rabies virus fabs
|
|
EP3095793B1
(en)
|
2003-07-28 |
2020-03-25 |
Genentech, Inc. |
Reducing protein a leaching during protein a affinity chromatography
|
|
JP2007504164A
(ja)
*
|
2003-08-29 |
2007-03-01 |
セダーズ−シナイ メディカル センター |
PPAR−γ経路およびHER−キナーゼ軸の調節に基づく癌および他の生理学的状態の処置のための組成物および方法
|
|
SG146644A1
(en)
*
|
2003-09-18 |
2008-10-30 |
Raven Biotechnologies Inc |
Kid3 and kid3 antibodies that bind thereto
|
|
BRPI0416987A
(pt)
*
|
2003-11-28 |
2007-08-21 |
Mitra Medical Technology Ab |
direcionamento de antìgenos de erb
|
|
RU2402568C2
(ru)
*
|
2004-02-06 |
2010-10-27 |
МорфоСис АГ |
Человеческие анти-cd38-антитела и их применение
|
|
RU2273475C2
(ru)
*
|
2004-04-06 |
2006-04-10 |
Государственное учреждение системы высшего и послевузовского профессионального образования "Сибирский государственный медицинский университет" (ГУ СВ ПО СибГМУ) |
Способ лечения диссеминированного колоректального рака
|
|
CA2567520A1
(en)
*
|
2004-06-01 |
2005-12-15 |
Genentech, Inc. |
Maytansinoid-antibody conjugates
|
|
GT200500155A
(es)
*
|
2004-06-16 |
2006-05-15 |
|
Terapia del càncer resistente al platino
|
|
RS53594B1
(sr)
|
2004-07-22 |
2015-02-27 |
Genentech, Inc. |
Preparat her2 antitela
|
|
US20100111856A1
(en)
|
2004-09-23 |
2010-05-06 |
Herman Gill |
Zirconium-radiolabeled, cysteine engineered antibody conjugates
|
|
EP3088004B1
(en)
|
2004-09-23 |
2018-03-28 |
Genentech, Inc. |
Cysteine engineered antibodies and conjugates
|
|
JO3000B1
(ar)
|
2004-10-20 |
2016-09-05 |
Genentech Inc |
مركبات أجسام مضادة .
|
|
BRPI0518086A
(pt)
*
|
2004-12-07 |
2008-10-28 |
Genentech Inc |
métodos para tratamento de cáncer, métodos de avaliação de fosforilação ou ativação de her e método de identificação
|
|
CN102580084B
(zh)
|
2005-01-21 |
2016-11-23 |
健泰科生物技术公司 |
Her抗体的固定剂量给药
|
|
MX2007009889A
(es)
|
2005-02-23 |
2007-09-07 |
Genentech Inc |
Alargar el tiempo hasta la progresion de la enfermedad o la supervivencia de los pacientes de cancer.
|
|
AR053272A1
(es)
*
|
2005-05-11 |
2007-04-25 |
Hoffmann La Roche |
Determinacion de responsivos a la quimioterapia
|
|
AU2006255686A1
(en)
|
2005-06-06 |
2006-12-14 |
Genentech, Inc. |
Transgenic models for different genes and their use for gene characterization
|
|
US7700299B2
(en)
|
2005-08-12 |
2010-04-20 |
Hoffmann-La Roche Inc. |
Method for predicting the response to a treatment
|
|
EP1922410A2
(en)
|
2005-08-15 |
2008-05-21 |
Genentech, Inc. |
Gene disruptions, compositions and methods relating thereto
|
|
KR101164820B1
(ko)
|
2005-09-22 |
2012-07-12 |
삼성전자주식회사 |
디스플레이장치
|
|
US8080534B2
(en)
|
2005-10-14 |
2011-12-20 |
Phigenix, Inc |
Targeting PAX2 for the treatment of breast cancer
|
|
JP2009516514A
(ja)
|
2005-11-21 |
2009-04-23 |
ジェネンテック・インコーポレーテッド |
新規遺伝子破壊、それらに関する組成物および方法
|
|
AR056857A1
(es)
|
2005-12-30 |
2007-10-24 |
U3 Pharma Ag |
Anticuerpos dirigidos hacia her-3 (receptor del factor de crecimiento epidérmico humano-3) y sus usos
|
|
JO2660B1
(en)
|
2006-01-20 |
2012-06-17 |
نوفارتيس ايه جي |
Pi-3 inhibitors and methods of use
|
|
EP1988768A2
(en)
|
2006-02-17 |
2008-11-12 |
Genentech, Inc. |
Gene disruptions, compositions and methods relating thereto
|
|
TW200812615A
(en)
|
2006-03-22 |
2008-03-16 |
Hoffmann La Roche |
Tumor therapy with an antibody for vascular endothelial growth factor and an antibody for human epithelial growth factor receptor type 2
|
|
TW200808739A
(en)
|
2006-04-06 |
2008-02-16 |
Novartis Vaccines & Diagnostic |
Quinazolines for PDK1 inhibition
|
|
EP2082645A1
(en)
|
2006-04-19 |
2009-07-29 |
Genentech, Inc. |
Novel gene disruptions, compositions and methods relating thereto
|
|
US8524865B2
(en)
|
2006-05-30 |
2013-09-03 |
Genentech, Inc. |
Antibodies and immunoconjugates and uses therefor
|
|
CA2654584A1
(en)
*
|
2006-06-05 |
2007-12-21 |
Genentech, Inc. |
Extending survival of cancer patients with elevated levels of egf or tgf-alpha
|
|
EP2056874B1
(en)
|
2006-08-21 |
2012-09-19 |
F. Hoffmann-La Roche AG |
Tumor therapy with an anti-vegf antibody
|
|
WO2008031531A1
(en)
*
|
2006-09-15 |
2008-03-20 |
F. Hoffmann-La Roche Ag |
Tumor therapy with a combination of anti-her2 antibodies
|
|
WO2008047723A1
(fr)
|
2006-10-12 |
2008-04-24 |
Forerunner Pharma Research Co., Ltd. |
Diagnostic et traitement du cancer à l'aide d'un anticorps anti-ereg
|
|
MX2009003938A
(es)
|
2006-10-27 |
2009-04-24 |
Genentech Inc |
Anticuerpos e inmunoconjugados y sus usos.
|
|
ES2477497T3
(es)
*
|
2007-03-02 |
2014-07-17 |
Genentech, Inc. |
Predicción de la respuesta a un inhibidor de la dimerización de HER basado en la expresión de HER3 bajo
|
|
US9551033B2
(en)
|
2007-06-08 |
2017-01-24 |
Genentech, Inc. |
Gene expression markers of tumor resistance to HER2 inhibitor treatment
|
|
CA3006428A1
(en)
|
2007-06-08 |
2008-12-18 |
Genentech, Inc. |
Gene expression markers of tumor resistance to her2 inhibitor treatment
|
|
JP2010530437A
(ja)
*
|
2007-06-18 |
2010-09-09 |
メディミューン,エルエルシー |
EphA2およびErbB2を発現する細胞の相乗的治療
|
|
ES2528922T3
(es)
|
2007-07-16 |
2015-02-13 |
Genentech, Inc. |
Anticuerpos anti-CD79b humanizados e inmunoconjugados y métodos de uso
|
|
RS53595B1
(sr)
|
2007-07-16 |
2015-02-27 |
Genentech, Inc. |
Anti-cd79b antitela i imunokonjugati i metode upotrebe
|
|
US20090148435A1
(en)
|
2007-10-30 |
2009-06-11 |
Genentech, Inc. |
Antibody purification by cation exchange chromatography
|
|
CA2706200A1
(en)
*
|
2007-11-27 |
2009-06-04 |
Ablynx N.V. |
Immunoglobulin constructs comprising multiple single variable domains and an fc portion
|
|
EA201000947A1
(ru)
|
2007-12-20 |
2011-02-28 |
Новартис Аг |
Производные тиазола, применимые в качестве ингибиторов киназы pi3
|
|
US8454960B2
(en)
|
2008-01-03 |
2013-06-04 |
The Scripps Research Institute |
Multispecific antibody targeting and multivalency through modular recognition domains
|
|
US8574577B2
(en)
|
2008-01-03 |
2013-11-05 |
The Scripps Research Institute |
VEGF antibodies comprising modular recognition domains
|
|
US8557243B2
(en)
|
2008-01-03 |
2013-10-15 |
The Scripps Research Institute |
EFGR antibodies comprising modular recognition domains
|
|
CN115043946A
(zh)
|
2008-01-03 |
2022-09-13 |
斯克里普斯研究院 |
通过模块识别结构域的抗体靶向
|
|
US8557242B2
(en)
|
2008-01-03 |
2013-10-15 |
The Scripps Research Institute |
ERBB2 antibodies comprising modular recognition domains
|
|
TWI472339B
(zh)
|
2008-01-30 |
2015-02-11 |
Genentech Inc |
包含結合至her2結構域ii之抗體及其酸性變異體的組合物
|
|
IL287292B
(en)
|
2008-01-31 |
2022-09-01 |
Genentech Inc |
Cycteine engineering anti-cd79b antibodies and antibody-drug conjugates
|
|
KR20160066557A
(ko)
|
2008-03-14 |
2016-06-10 |
제넨테크, 인크. |
약물 저항성과 관련된 유전적 변이
|
|
US8663643B2
(en)
*
|
2008-03-18 |
2014-03-04 |
Genentech, Inc. |
Combinations of an anti-HER2 antibody-drug conjugate and chemotherapeutic agents, and methods of use
|
|
DK2789684T3
(en)
|
2008-05-23 |
2017-02-20 |
Siwa Corp |
Methods and compositions for facilitating regeneration
|
|
BRPI0812682A2
(pt)
|
2008-06-16 |
2010-06-22 |
Genentech Inc |
tratamento de cáncer de mama metastático
|
|
CN103599541A
(zh)
|
2008-09-10 |
2014-02-26 |
弗·哈夫曼-拉罗切有限公司 |
用于防止蛋白质氧化降解的组合物和方法
|
|
EP3903829B1
(en)
|
2009-02-13 |
2023-05-03 |
Immunomedics, Inc. |
Immunoconjugates with an intracellularly-cleavable linkage
|
|
AR075896A1
(es)
|
2009-03-20 |
2011-05-04 |
Genentech Inc |
Anticuerpos anti-her (factor de crecimiento epidermico)
|
|
WO2010120561A1
(en)
|
2009-04-01 |
2010-10-21 |
Genentech, Inc. |
Anti-fcrh5 antibodies and immunoconjugates and methods of use
|
|
SG175078A1
(en)
|
2009-04-07 |
2011-11-28 |
Roche Glycart Ag |
Bispecific anti-erbb-1/anti-c-met antibodies
|
|
SG176073A1
(en)
|
2009-05-29 |
2011-12-29 |
Hoffmann La Roche |
Modulators for her2 signaling in her2 expressing patients with gastric cancer
|
|
JP5808052B2
(ja)
|
2009-05-29 |
2015-11-10 |
中外製薬株式会社 |
Egfファミリーリガンドのアンタゴニストを成分とする医薬組成物
|
|
US8293753B2
(en)
|
2009-07-02 |
2012-10-23 |
Novartis Ag |
Substituted 2-carboxamide cycloamino ureas
|
|
US9345661B2
(en)
|
2009-07-31 |
2016-05-24 |
Genentech, Inc. |
Subcutaneous anti-HER2 antibody formulations and uses thereof
|
|
SI2464725T2
(sl)
|
2009-08-11 |
2025-06-30 |
F. Hoffmann-La Roche Ag |
Proizvodnja beljakovin v medijih za celične kulture brez glutamina
|
|
JP6088246B2
(ja)
*
|
2009-08-15 |
2017-03-01 |
ジェネンテック, インコーポレイテッド |
以前に治療された乳癌の治療のための抗血管新生療法
|
|
CN102686738A
(zh)
|
2009-09-01 |
2012-09-19 |
弗·哈夫曼-拉罗切有限公司 |
通过改进的a蛋白洗脱增强的蛋白质纯化
|
|
AR078161A1
(es)
|
2009-09-11 |
2011-10-19 |
Hoffmann La Roche |
Formulaciones farmaceuticas muy concentradas de un anticuerpo anti cd20. uso de la formulacion. metodo de tratamiento.
|
|
TR201804897T4
(tr)
|
2009-10-07 |
2018-06-21 |
Macrogenics Inc |
Fukosi̇lasyon ölçüsünün deği̇şi̇mleri̇nden dolayi geli̇şmi̇ş efektör i̇şlevi̇ sergi̇leyen fc bölgesi̇ni̇ i̇çeren poli̇pepti̇tler ve bunlarin kullanimlarina yöneli̇k yöntemler
|
|
US8658175B2
(en)
*
|
2009-10-28 |
2014-02-25 |
Abbvie Biotherapeutics Inc. |
Anti-EGFR antibodies and their uses
|
|
CA2780143A1
(en)
|
2009-11-05 |
2011-05-12 |
Genentech, Inc. |
Methods and composition for secretion of heterologous polypeptides
|
|
KR101806323B1
(ko)
|
2009-11-13 |
2017-12-07 |
다이이치 산쿄 유럽 게엠베하 |
Her-3 관련 질병을 치료하거나 예방하기 위한 물질 및 방법
|
|
US10584181B2
(en)
|
2009-12-04 |
2020-03-10 |
Genentech, Inc. |
Methods of making and using multispecific antibody panels and antibody analog panels
|
|
CN102821788B
(zh)
*
|
2010-02-04 |
2016-11-16 |
东丽株式会社 |
癌的治疗和/或预防用药物组合物
|
|
SG183333A1
(en)
|
2010-02-18 |
2012-09-27 |
Genentech Inc |
Neuregulin antagonists and use thereof in treating cancer
|
|
US8609095B2
(en)
|
2010-03-04 |
2013-12-17 |
Symphogen A/S |
Anti-HER2 antibodies and compositions
|
|
RU2584232C2
(ru)
|
2010-03-22 |
2016-05-20 |
Дженентек, Инк. |
Композиции и способы, используемые для стабилизации белоксодержащих готовых форм
|
|
RU2012151500A
(ru)
|
2010-05-03 |
2014-06-10 |
Дженентек, Инк. |
Композиции и способы, пригодные для снижения вязкости белковосодержащих составов
|
|
WO2011146568A1
(en)
|
2010-05-19 |
2011-11-24 |
Genentech, Inc. |
Predicting response to a her inhibitor
|
|
CA2800769C
(en)
|
2010-05-27 |
2021-11-02 |
Genmab A/S |
Monoclonal antibodies against her2 epitope
|
|
IL299365A
(en)
|
2010-05-27 |
2023-02-01 |
Genmab As |
Monoclonal antibodies against 2HER
|
|
KR20190067277A
(ko)
|
2010-05-28 |
2019-06-14 |
제넨테크, 인크. |
락테이트 데히드로게나제 및 피루베이트 데히드로게나제 키나제의 발현의 하향조절에 의한 락테이트 수준의 감소 및 폴리펩티드 생산의 증가
|
|
AU2011261362B2
(en)
|
2010-06-03 |
2016-06-09 |
Genentech, Inc. |
Immuno-pet imaging of antibodies and immunoconjugates and uses therefor
|
|
CA2799540A1
(en)
|
2010-06-08 |
2011-12-15 |
Genentech, Inc. |
Cysteine engineered antibodies and conjugates
|
|
PL3586826T3
(pl)
|
2010-06-24 |
2021-10-25 |
F. Hoffmann-La Roche Ag |
Kompozycje i sposoby stabilizowania preparatów zawierających białka
|
|
WO2012009705A1
(en)
|
2010-07-15 |
2012-01-19 |
Zyngenia, Inc. |
Ang-2 binding complexes and uses thereof
|
|
AR082418A1
(es)
|
2010-08-02 |
2012-12-05 |
Novartis Ag |
Formas cristalinas de 1-(4-metil-5-[2-(2,2,2-trifluoro-1,1-dimetil-etil)-piridin-4-il]-tiazol-2-il)-amida de 2-amida del acido (s)-pirrolidin-1,2-dicarboxilico
|
|
TW201302793A
(zh)
|
2010-09-03 |
2013-01-16 |
Glaxo Group Ltd |
新穎之抗原結合蛋白
|
|
US8721571B2
(en)
|
2010-11-22 |
2014-05-13 |
Siwa Corporation |
Selective removal of cells having accumulated agents
|
|
WO2012069466A1
(en)
|
2010-11-24 |
2012-05-31 |
Novartis Ag |
Multispecific molecules
|
|
EP2655412B1
(en)
|
2010-12-21 |
2018-01-17 |
F. Hoffmann-La Roche AG |
Isoform enriched antibody preparation and method for obtaining it
|
|
CN103384681B
(zh)
|
2010-12-23 |
2018-05-18 |
霍夫曼-拉罗奇有限公司 |
结合剂
|
|
SG191153A1
(en)
|
2010-12-23 |
2013-07-31 |
Hoffmann La Roche |
Polypeptide-polynucleotide-complex and its use in targeted effector moiety delivery
|
|
US8987257B2
(en)
|
2011-01-31 |
2015-03-24 |
Novartis Ag |
Heterocyclic derivatives
|
|
CN103649326B
(zh)
*
|
2011-03-08 |
2016-08-17 |
宾夕法尼亚大学理事会 |
用于治疗和诊断用途的抗体样蛋白
|
|
US20140170149A1
(en)
|
2011-04-20 |
2014-06-19 |
Genmab A/S |
Bispecific antibodies against her2 and cd3
|
|
DK2714738T3
(en)
|
2011-05-24 |
2019-01-28 |
Zyngenia Inc |
MULTIVALENT AND MONOVALENT MULTISPECIFIC COMPLEXES AND THEIR APPLICATIONS
|
|
CA2842375A1
(en)
|
2011-08-17 |
2013-02-21 |
Erica Jackson |
Neuregulin antibodies and uses thereof
|
|
WO2013055874A2
(en)
|
2011-10-14 |
2013-04-18 |
Genentech, Inc. |
Uses for and article of manufacture including her2 dimerization inhibitor pertuzumab
|
|
US9327023B2
(en)
|
2011-10-25 |
2016-05-03 |
The Regents Of The University Of Michigan |
HER2 targeting agent treatment in non-HER2-amplified cancers having HER2 expressing cancer stem cells
|
|
KR20140090218A
(ko)
|
2011-10-28 |
2014-07-16 |
노파르티스 아게 |
신규 퓨린 유도체 및 질환의 치료에서의 그의 용도
|
|
RU2620068C2
(ru)
|
2011-11-23 |
2017-05-22 |
МЕДИММЬЮН, ЭлЭлСи |
Связывающие молекулы, специфичные по отношению к her3, и их применения
|
|
EP2785864A2
(en)
|
2011-11-30 |
2014-10-08 |
F. Hoffmann-La Roche AG |
Erbb3 mutations in cancer
|
|
WO2013083810A1
(en)
|
2011-12-09 |
2013-06-13 |
F. Hoffmann-La Roche Ag |
Identification of non-responders to her2 inhibitors
|
|
HRP20181846T1
(hr)
|
2011-12-22 |
2018-12-28 |
Genentech, Inc. |
Kromatografija membranom za ionsku izmjenu
|
|
TWI593705B
(zh)
|
2011-12-28 |
2017-08-01 |
Chugai Pharmaceutical Co Ltd |
Humanized anti-epiregulin antibody and cancer therapeutic agent containing the antibody as an active ingredient
|
|
AU2013214254B2
(en)
|
2012-01-31 |
2016-04-21 |
Novartis Ag |
Method of treating cancer
|
|
EP2638916A1
(en)
|
2012-03-16 |
2013-09-18 |
Covagen AG |
Novel binding molecules with antitumoral activity
|
|
CA2865082A1
(en)
|
2012-03-27 |
2013-10-03 |
Genentech, Inc. |
Diagnosis and treatments relating to her3 inhibitors
|
|
PT2838917T
(pt)
|
2012-04-20 |
2019-09-12 |
Merus Nv |
Métodos e meios para a produção de moléculas similares a ig heterodiméricas
|
|
KR101505157B1
(ko)
|
2012-05-08 |
2015-03-24 |
주식회사 종근당 |
항―ErbB2 항체 변이체
|
|
HK1202435A1
(en)
|
2012-05-16 |
2015-10-02 |
Novartis Ag |
Dosage regimen for a pi-3 kinase inhibitor
|
|
CA2889298C
(en)
|
2012-11-30 |
2024-01-02 |
Anton Belousov |
Identification of patients in need of pd-l1 inhibitor cotherapy
|
|
ES2651331T3
(es)
|
2013-01-10 |
2018-01-25 |
Glaxosmithkline Intellectual Property (No. 2) Limited |
Inhibidores de la sintasa de ácidos grasos
|
|
AR094403A1
(es)
|
2013-01-11 |
2015-07-29 |
Hoffmann La Roche |
Terapia de combinación de anticuerpos anti-her3
|
|
MX2015013163A
(es)
|
2013-03-15 |
2016-04-04 |
Zyngenia Inc |
Complejos multiespecificos multivalente y monovalentes y sus usos.
|
|
CN104628846B
(zh)
|
2013-11-06 |
2019-12-06 |
三生国健药业(上海)股份有限公司 |
重组蛋白质的纯化方法
|
|
RS62157B1
(sr)
*
|
2013-11-19 |
2021-08-31 |
Remegen Co Ltd |
Anti-her2 antitelo i njegov konjugat
|
|
ES3030987T3
(en)
|
2013-11-27 |
2025-07-03 |
Zymeworks Bc Inc |
Bispecific antigen-binding constructs targeting her2
|
|
MX378409B
(es)
|
2013-12-06 |
2025-03-10 |
Novartis Ag |
Regimen de dosificacion para un inhibidor selectivo alfa-isomorfo de fosfatidilinositol 3-quinasa.
|
|
PH12020552271A1
(en)
|
2014-01-31 |
2022-05-02 |
Daiichi Sankyo Co Ltd |
Anti-her2 antibody-drug conjugate
|
|
EP3111222A1
(en)
|
2014-02-26 |
2017-01-04 |
Glaxosmithkline Intellectual Property (No. 2) Limited |
Methods of treating cancer patients responding to ezh2 inhibitor gsk126
|
|
WO2015139046A1
(en)
|
2014-03-14 |
2015-09-17 |
Genentech, Inc. |
Methods and compositions for secretion of heterologous polypeptides
|
|
HK1232127A1
(zh)
|
2014-04-11 |
2018-01-05 |
Medimmune, Llc |
双特异性her2抗体
|
|
EP3388449A3
(en)
|
2014-09-12 |
2018-10-24 |
F. Hoffmann-La Roche AG |
Cysteine engineered antibodies and conjugates
|
|
AU2015318036B2
(en)
|
2014-09-19 |
2021-07-01 |
Siwa Corporation |
Anti-AGE antibodies for treating inflammation and auto-immune disorders
|
|
US10385380B2
(en)
|
2014-10-02 |
2019-08-20 |
The Regents Of The University Of California |
Personalized protease assay to measure protease activity in neoplasms
|
|
DK3223848T3
(da)
|
2014-11-27 |
2025-03-03 |
Zymeworks Bc Inc |
Fremgangsmåder til anvendelse af bispecifikke antigenbindingskonstrukter målrettet her2
|
|
US10358502B2
(en)
|
2014-12-18 |
2019-07-23 |
Siwa Corporation |
Product and method for treating sarcopenia
|
|
US9993535B2
(en)
|
2014-12-18 |
2018-06-12 |
Siwa Corporation |
Method and composition for treating sarcopenia
|
|
MA41414A
(fr)
|
2015-01-28 |
2017-12-05 |
Centre Nat Rech Scient |
Protéines de liaison agonistes d' icos
|
|
KR101515535B1
(ko)
|
2015-01-28 |
2015-05-06 |
주식회사 종근당 |
항―ErbB2 항체 변이체
|
|
CA2984458A1
(en)
*
|
2015-05-13 |
2016-11-17 |
Zymeworks Inc. |
Antigen-binding constructs targeting her2
|
|
US20180230431A1
(en)
|
2015-08-07 |
2018-08-16 |
Glaxosmithkline Intellectual Property Development Limited |
Combination Therapy
|
|
MX2018004545A
(es)
*
|
2015-10-13 |
2018-08-01 |
Siwa Corp |
Anticuerpos anti-age y metodos para utilizarlos.
|
|
WO2017077445A1
(en)
|
2015-11-02 |
2017-05-11 |
Novartis Ag |
Dosage regimen for a phosphatidylinositol 3-kinase inhibitor
|
|
CN106729743B
(zh)
|
2015-11-23 |
2021-09-21 |
四川科伦博泰生物医药股份有限公司 |
抗ErbB2抗体-药物偶联物及其组合物、制备方法和应用
|
|
CA3006934A1
(en)
|
2015-12-01 |
2017-06-08 |
Glaxosmithkline Intellectual Property Development Limited |
Combination of antibodies targeting bcma, pd-1 and ox40 in cancer treatments and uses therof
|
|
AU2016370376B2
(en)
|
2015-12-14 |
2023-12-14 |
Macrogenics, Inc. |
Bispecific molecules having immunoreactivity with PD-1 and CTLA-4, and methods of use thereof
|
|
CN105646704B
(zh)
*
|
2015-12-28 |
2019-11-15 |
广西医科大学 |
抗p185erbB2人鼠嵌合抗体ChAb26、乳腺特异性表达载体、转基因FVB小鼠及其制备方法
|
|
EP4067386A1
(en)
|
2016-02-19 |
2022-10-05 |
Siwa Corporation |
Method and composition for treating cancer, killing metastatic cancer cells and preventing cancer metastasis using antibody to advanced glycation end products (age)
|
|
BR112018068512A2
(pt)
*
|
2016-03-15 |
2019-01-22 |
Merrimack Pharmaceuticals Inc |
métodos para tratar câncer de mama er+, her2-, hrg+ com o uso de terapias de combinação que compreendem um anticorpo anti-erbb3
|
|
US11958900B2
(en)
|
2016-04-15 |
2024-04-16 |
Siwa Corporation |
Anti-age antibodies for treating neurodegenerative disorders
|
|
US20190151346A1
(en)
|
2016-05-10 |
2019-05-23 |
INSERM (Institute National de la Santé et de la Recherche Médicale) |
Combinations therapies for the treatment of cancer
|
|
US11142585B2
(en)
*
|
2016-05-12 |
2021-10-12 |
Agency For Science, Technology And Research |
Anti-ERBB-2 antibodies and uses thereof
|
|
WO2017222535A1
(en)
|
2016-06-23 |
2017-12-28 |
Siwa Corporation |
Vaccines for use in treating various diseases and disorders
|
|
WO2018060833A1
(en)
|
2016-09-27 |
2018-04-05 |
Novartis Ag |
Dosage regimen for alpha-isoform selective phosphatidylinositol 3-kinase inhibitor alpelisib
|
|
CA3036941C
(en)
|
2016-10-07 |
2023-02-21 |
Daiichi Sankyo Company, Limited |
Therapy for drug-resistant cancer by administration of anti-her2 antibody/drug conjugate
|
|
CN110049779A
(zh)
|
2016-12-12 |
2019-07-23 |
第一三共株式会社 |
抗体-药物缀合物和免疫检查点抑制剂的组合
|
|
KR102646046B1
(ko)
*
|
2017-01-06 |
2024-03-08 |
바이오션, 인코포레이티드 |
Erbb2 항체 및 이의 용도
|
|
US10995151B1
(en)
|
2017-01-06 |
2021-05-04 |
Siwa Corporation |
Methods and compositions for treating disease-related cachexia
|
|
US10925937B1
(en)
|
2017-01-06 |
2021-02-23 |
Siwa Corporation |
Vaccines for use in treating juvenile disorders associated with inflammation
|
|
US10961321B1
(en)
|
2017-01-06 |
2021-03-30 |
Siwa Corporation |
Methods and compositions for treating pain associated with inflammation
|
|
US10858449B1
(en)
|
2017-01-06 |
2020-12-08 |
Siwa Corporation |
Methods and compositions for treating osteoarthritis
|
|
BR112019017628A2
(pt)
|
2017-02-24 |
2020-07-07 |
Macrogenics, Inc. |
molécula de ligação a cd137 x ta, composições farmacêuticas, uso da molécula de ligação a cd137 x ta, molécula de ligação a cd137, uso da molécula de ligação a cd137, molécula de ligação a her2/neu, uso da molécula de ligação a her2/neu, e uso de uma composição
|
|
WO2018160138A1
(en)
|
2017-03-02 |
2018-09-07 |
Aslan Pharmaceuticals Pte Ltd |
Dhodh inhibitor for treating haematological cancer
|
|
LT3589661T
(lt)
|
2017-03-02 |
2024-02-12 |
Genentech, Inc. |
Adjuvantinis her2 atžvilgiu teigiamo krūties vėžio gydymas
|
|
AR111249A1
(es)
|
2017-03-22 |
2019-06-19 |
Genentech Inc |
Composiciones de anticuerpo optimizadas para el tratamiento de trastornos oculares
|
|
EP3609923A1
(en)
|
2017-04-13 |
2020-02-19 |
Siwa Corporation |
Humanized monoclonal advanced glycation end-product antibody
|
|
WO2018222135A1
(en)
|
2017-06-02 |
2018-12-06 |
Aslan Pharmaceuticals Pte Ltd |
Cancer therapy
|
|
CN107417791B
(zh)
*
|
2017-08-17 |
2020-09-22 |
合肥瀚科迈博生物技术有限公司 |
抗人ErbB2双特异性抗体、其制备方法及用途
|
|
EP3673918A4
(en)
|
2017-08-23 |
2021-05-19 |
Daiichi Sankyo Company, Limited |
PREPARATION OF AN ANTIBODY INGREDIENT CONJUGATE AND LYOPHILIZATION FOR IT
|
|
KR20250084239A
(ko)
|
2017-08-31 |
2025-06-10 |
다이이찌 산쿄 가부시키가이샤 |
항체-약물 콘주게이트의 개량 제조 방법
|
|
CA3074208C
(en)
|
2017-08-31 |
2023-10-03 |
Daiichi Sankyo Company, Limited |
Novel method for producing antibody-drug conjugate
|
|
CN107789631B
(zh)
*
|
2017-11-03 |
2021-03-16 |
合肥瀚科迈博生物技术有限公司 |
抗人ErbB2双表位抗体-药物偶联物及其应用
|
|
SG11202005557TA
(en)
|
2017-12-12 |
2020-07-29 |
Macrogenics Inc |
Bispecific cd 16-binding molecules and their use in the treatment of disease
|
|
US11518801B1
(en)
|
2017-12-22 |
2022-12-06 |
Siwa Corporation |
Methods and compositions for treating diabetes and diabetic complications
|
|
AU2019222666B2
(en)
|
2018-02-15 |
2025-12-04 |
Macrogenics, Inc. |
Variant CD3-binding domains and their use in combination therapies for the treatment of disease
|
|
EP3560945A1
(en)
|
2018-04-27 |
2019-10-30 |
F. Hoffmann-La Roche AG |
Methods for purification of polypeptides using polysorbates
|
|
WO2019230645A1
(ja)
|
2018-05-28 |
2019-12-05 |
第一三共株式会社 |
抗her2抗体-薬物コンジュゲート投与によるher2変異がんの治療
|
|
CN112703000B
(zh)
|
2018-07-23 |
2024-05-31 |
特雷维治疗股份有限公司 |
慢性咳嗽、呼吸急促和呼吸困难的治疗
|
|
TWI865337B
(zh)
|
2018-07-25 |
2024-12-01 |
日商第一三共股份有限公司 |
抗體-藥物結合物之有效的製造方法
|
|
WO2020022475A1
(ja)
|
2018-07-27 |
2020-01-30 |
第一三共株式会社 |
抗体-薬物コンジュゲートの薬物部位を認識する蛋白質
|
|
US12220604B2
(en)
|
2018-07-31 |
2025-02-11 |
Daiichi Sankyo Company, Limited |
Treatment of metastatic brain tumor by administration of an antibody-drug conjugate
|
|
KR20210042120A
(ko)
|
2018-08-06 |
2021-04-16 |
다이이찌 산쿄 가부시키가이샤 |
항체-약물 콘주게이트와 튜불린 저해제의 조합
|
|
JP7481255B2
(ja)
|
2018-08-23 |
2024-05-10 |
第一三共株式会社 |
抗体薬物複合体の感受性マーカー
|
|
CN113286810A
(zh)
|
2018-09-25 |
2021-08-20 |
Absci有限责任公司 |
蛋白质纯化方法
|
|
WO2020084503A1
(en)
|
2018-10-26 |
2020-04-30 |
Cadila Healthcare Limited |
A composition comprising antibody with reduced level of basic variants thereof
|
|
KR20210102341A
(ko)
|
2018-12-11 |
2021-08-19 |
다이이찌 산쿄 가부시키가이샤 |
항체-약물 컨쥬게이트와 parp 저해제의 조합
|
|
MX2021007260A
(es)
|
2018-12-19 |
2021-09-08 |
Incyte Corp |
Inhibidores de la vía de cinasa janus 1 (jak1) para el tratamiento de enfermedades gastrointestinales.
|
|
CN113195000A
(zh)
|
2018-12-21 |
2021-07-30 |
第一三共株式会社 |
抗体-药物缀合物和激酶抑制剂的组合
|
|
MX2021009189A
(es)
|
2019-02-01 |
2021-11-12 |
Glaxosmithkline Ip Dev Ltd |
Belantamab mafodotin en combinación con pembrolizumab para el tratamiento del cáncer.
|
|
WO2020205716A1
(en)
|
2019-04-01 |
2020-10-08 |
Genentech, Inc. |
Compositions and methods for stabilizing protein-containing formulations
|
|
CN112007169B
(zh)
*
|
2019-05-30 |
2022-03-08 |
湖南大学 |
一种核酸适配体药物偶联物及其制备方法和用途
|
|
CN110205302B
(zh)
*
|
2019-06-24 |
2021-03-23 |
扬州大学 |
一株分泌抗麦考酚酸单克隆抗体的细胞株、其单克隆抗体及其应用
|
|
WO2020261097A1
(en)
|
2019-06-26 |
2020-12-30 |
Glaxosmithkline Intellectual Property Development Limited |
Il1rap binding proteins
|
|
CN110551214A
(zh)
*
|
2019-08-27 |
2019-12-10 |
杨澜 |
一种人源化抗Periostin单克隆抗体、及其制备方法和应用
|
|
AU2021206252A1
(en)
|
2020-01-10 |
2022-07-28 |
Trevi Therapeutics, Inc. |
Methods of administering nalbuphine
|
|
CA3167689A1
(en)
|
2020-01-28 |
2021-08-05 |
Glaxosmithkline Intellectual Property Development Limited |
Combination treatments and uses and methods thereof
|
|
CN115279403A
(zh)
|
2020-02-21 |
2022-11-01 |
宏观基因有限公司 |
Cd137结合分子及其用途
|
|
KR20230043109A
(ko)
|
2020-06-24 |
2023-03-30 |
아스트라제네카 유케이 리미티드 |
항체-약물 접합체 및 atr 억제제의 조합
|
|
TW202216207A
(zh)
|
2020-06-24 |
2022-05-01 |
英商阿斯特捷利康英國股份有限公司 |
抗體-藥物結合物及cdk9抑制劑之組合
|
|
EP4171651A1
(en)
|
2020-06-24 |
2023-05-03 |
AstraZeneca UK Limited |
Combination of antibody-drug conjugate and atm inhibitor
|
|
WO2021260582A1
(en)
|
2020-06-24 |
2021-12-30 |
Astrazeneca Uk Limited |
Combination of antibody-drug conjugate and aurora b inhibitor
|
|
WO2021260583A1
(en)
|
2020-06-24 |
2021-12-30 |
Astrazeneca Uk Limited |
Combination of antibody-drug conjugate and dna-pk inhibitor
|
|
KR20230042055A
(ko)
|
2020-07-20 |
2023-03-27 |
다이이찌 산쿄 가부시키가이샤 |
항 her2 항체-약물 콘주게이트와 her 이량체화 저해제의 조합
|
|
EP4225314A1
(en)
|
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