SG11202100947SA - Treatment of metastatic brain tumor by administration of antibody-drug conjugate - Google Patents
Treatment of metastatic brain tumor by administration of antibody-drug conjugateInfo
- Publication number
- SG11202100947SA SG11202100947SA SG11202100947SA SG11202100947SA SG11202100947SA SG 11202100947S A SG11202100947S A SG 11202100947SA SG 11202100947S A SG11202100947S A SG 11202100947SA SG 11202100947S A SG11202100947S A SG 11202100947SA SG 11202100947S A SG11202100947S A SG 11202100947SA
- Authority
- SG
- Singapore
- Prior art keywords
- antibody
- administration
- treatment
- drug conjugate
- brain tumor
- Prior art date
Links
- 208000003174 Brain Neoplasms Diseases 0.000 title 1
- 239000000611 antibody drug conjugate Substances 0.000 title 1
- 229940049595 antibody-drug conjugate Drugs 0.000 title 1
- 230000001394 metastastic effect Effects 0.000 title 1
- 206010061289 metastatic neoplasm Diseases 0.000 title 1
Classifications
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- A61K47/6889—Conjugates wherein the antibody being the modifying agent and wherein the linker, binder or spacer confers particular properties to the conjugates, e.g. peptidic enzyme-labile linkers or acid-labile linkers, providing for an acid-labile immuno conjugate wherein the drug may be released from its antibody conjugated part in an acidic, e.g. tumoural or environment
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- Health & Medical Sciences (AREA)
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- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
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- Proteomics, Peptides & Aminoacids (AREA)
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- Zoology (AREA)
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- Mycology (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
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JP2018143372 | 2018-07-31 | ||
PCT/JP2019/029765 WO2020027100A1 (en) | 2018-07-31 | 2019-07-30 | Treatment of metastatic brain tumor by administration of antibody-drug conjugate |
Publications (1)
Publication Number | Publication Date |
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SG11202100947SA true SG11202100947SA (en) | 2021-03-30 |
Family
ID=69230857
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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SG11202100947SA SG11202100947SA (en) | 2018-07-31 | 2019-07-30 | Treatment of metastatic brain tumor by administration of antibody-drug conjugate |
Country Status (13)
Country | Link |
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US (1) | US20210290777A1 (en) |
EP (1) | EP3831412A4 (en) |
JP (1) | JP7473474B2 (en) |
KR (1) | KR20210038625A (en) |
CN (1) | CN112805036A (en) |
AU (1) | AU2019315177A1 (en) |
BR (1) | BR112021001509A2 (en) |
CA (1) | CA3108044A1 (en) |
EA (1) | EA202190403A1 (en) |
IL (1) | IL280510A (en) |
SG (1) | SG11202100947SA (en) |
TW (1) | TWI822822B (en) |
WO (1) | WO2020027100A1 (en) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
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EP3673918A4 (en) * | 2017-08-23 | 2021-05-19 | Daiichi Sankyo Company, Limited | Antibody-drug conjugate preparation and lyophilization for same |
AU2020285681A1 (en) * | 2019-05-29 | 2022-01-27 | Daiichi Sankyo Company, Limited | Dosage of an antibody-drug conjugate |
EP4130036A4 (en) * | 2020-03-30 | 2024-05-15 | National Cancer Center | Antibody drug conjugate |
WO2023042097A1 (en) * | 2021-09-15 | 2023-03-23 | Daiichi Sankyo Company, Limited | Antibody-drug conjugate for use in methods of treating chemotherapy-resistant cancer |
WO2023141611A2 (en) * | 2022-01-21 | 2023-07-27 | Lyvgen Biopharma Holdings Limited | Multi-specific antibodies in uses thereof in avidity receptor crosslinking and immune modulation |
WO2023228095A1 (en) * | 2022-05-24 | 2023-11-30 | Daiichi Sankyo Company, Limited | Dosage regimen of an anti-cdh6 antibody-drug conjugate |
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IL162181A (en) | 1988-12-28 | 2006-04-10 | Pdl Biopharma Inc | A method of producing humanized immunoglubulin, and polynucleotides encoding the same |
EP1400536A1 (en) | 1991-06-14 | 2004-03-24 | Genentech Inc. | Method for making humanized antibodies |
PT1071700E (en) | 1998-04-20 | 2010-04-23 | Glycart Biotechnology Ag | Glycosylation engineering of antibodies for improving antibody-dependent cellular cytotoxicity |
ES2571230T3 (en) | 1999-04-09 | 2016-05-24 | Kyowa Hakko Kirin Co Ltd | Procedure to control the activity of an immunofunctional molecule |
AU784045B2 (en) | 1999-06-25 | 2006-01-19 | Genentech Inc. | Humanized anti-ErbB2 antibodies and treatment with anti-ErbB2 antibodies |
CN102311986B (en) | 2000-10-06 | 2015-08-19 | 协和发酵麒麟株式会社 | Produce the cell of antibody compositions |
AR056857A1 (en) | 2005-12-30 | 2007-10-24 | U3 Pharma Ag | DIRECTED ANTIBODIES TO HER-3 (RECEIVER OF THE HUMAN EPIDERMAL GROWTH FACTOR-3) AND ITS USES |
EP2001358B1 (en) | 2006-03-27 | 2016-07-13 | University Of Maryland, Baltimore | Glycoprotein synthesis and remodeling by enzymatic transglycosylation |
EP3248617A3 (en) | 2007-02-16 | 2018-02-21 | Merrimack Pharmaceuticals, Inc. | Antibodies against erbb3 and uses thereof |
IN2014DN06806A (en) | 2012-02-10 | 2015-05-22 | Univ Maryland | |
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AU2019315177A1 (en) | 2021-02-25 |
TWI822822B (en) | 2023-11-21 |
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