SI2283867T1 - Metode zdravljenja z majtanzinoidom konjugiranim protitelesom anti-ErbB - Google Patents

Metode zdravljenja z majtanzinoidom konjugiranim protitelesom anti-ErbB

Info

Publication number
SI2283867T1
SI2283867T1 SI200031080T SI200031080T SI2283867T1 SI 2283867 T1 SI2283867 T1 SI 2283867T1 SI 200031080 T SI200031080 T SI 200031080T SI 200031080 T SI200031080 T SI 200031080T SI 2283867 T1 SI2283867 T1 SI 2283867T1
Authority
SI
Slovenia
Prior art keywords
treatment
methods
maytansinoid conjugates
erbb antibody
erbb
Prior art date
Application number
SI200031080T
Other languages
English (en)
Inventor
Sharon Erickson
Ralph Schwall
Mark X. Sliwkowski
Walter Blattler
Original Assignee
Immunogen, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22495168&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SI2283867(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Immunogen, Inc. filed Critical Immunogen, Inc.
Priority claimed from EP10177413.1A external-priority patent/EP2283867B1/en
Publication of SI2283867T1 publication Critical patent/SI2283867T1/sl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/32—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
    • A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
    • A61K47/6807—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug or compound being a sugar, nucleoside, nucleotide, nucleic acid, e.g. RNA antisense
    • A61K47/6809—Antibiotics, e.g. antitumor antibiotics anthracyclins, adriamycin, doxorubicin or daunomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A61K2039/507—Comprising a combination of two or more separate antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mycology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Biophysics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Packages (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
SI200031080T 1999-06-25 2000-06-23 Metode zdravljenja z majtanzinoidom konjugiranim protitelesom anti-ErbB SI2283867T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US14131699P 1999-06-25 1999-06-25
US18984400P 2000-03-16 2000-03-16
EP10177413.1A EP2283867B1 (en) 1999-06-25 2000-06-23 Methods of treatment using anti-ERBB antibody-maytansinoid conjugates

Publications (1)

Publication Number Publication Date
SI2283867T1 true SI2283867T1 (sl) 2014-07-31

Family

ID=22495168

Family Applications (3)

Application Number Title Priority Date Filing Date
SI200031040T SI1189641T1 (sl) 1999-06-25 2000-06-23 Humanizirana protitelesa proti ErbB2 in zdravljenje s protitelesi proti ErbB2
SI200031088T SI2283866T1 (sl) 1999-06-25 2000-06-23 POSTOPKI ZA ZDRAVLJENJE Z UPORABO KONJUGATOV MAYNTASINOIDNIH PROTITELES PROTI ERbB
SI200031080T SI2283867T1 (sl) 1999-06-25 2000-06-23 Metode zdravljenja z majtanzinoidom konjugiranim protitelesom anti-ErbB

Family Applications Before (2)

Application Number Title Priority Date Filing Date
SI200031040T SI1189641T1 (sl) 1999-06-25 2000-06-23 Humanizirana protitelesa proti ErbB2 in zdravljenje s protitelesi proti ErbB2
SI200031088T SI2283866T1 (sl) 1999-06-25 2000-06-23 POSTOPKI ZA ZDRAVLJENJE Z UPORABO KONJUGATOV MAYNTASINOIDNIH PROTITELES PROTI ERbB

Country Status (33)

Country Link
EP (2) EP2112167A3 (sl)
JP (2) JP4283474B2 (sl)
KR (2) KR100850389B1 (sl)
CN (4) CN101121750A (sl)
AR (1) AR024464A1 (sl)
AT (2) ATE437655T1 (sl)
AU (2) AU784045B2 (sl)
BE (1) BE2013C020I2 (sl)
BR (2) BRPI0012198B8 (sl)
CA (2) CA2727172A1 (sl)
CH (1) CH694589A5 (sl)
CY (2) CY1109525T1 (sl)
CZ (1) CZ299702B6 (sl)
DE (2) DE10084743T1 (sl)
DK (1) DK1189641T5 (sl)
ES (1) ES2329437T3 (sl)
FR (1) FR13C0016I2 (sl)
GB (1) GB2368796B (sl)
GE (1) GEP20104998B (sl)
HK (1) HK1044888A1 (sl)
HU (1) HU226742B1 (sl)
IL (3) IL146954A0 (sl)
LU (1) LU92164I2 (sl)
MX (1) MXPA01013458A (sl)
NO (3) NO328377B1 (sl)
NZ (2) NZ516830A (sl)
PL (2) PL204629B1 (sl)
PT (1) PT1189641E (sl)
RU (2) RU2270029C2 (sl)
SI (3) SI1189641T1 (sl)
TR (1) TR200103756T2 (sl)
WO (1) WO2001000245A2 (sl)
ZA (2) ZA200109786B (sl)

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