CZ299702B6 - Protilátka, imunokonjugát, izolovaná nukleová kyselina, vektor, hostitelská bunka, zpusob výroby protilátky a farmaceutický prostredek ji obsahující - Google Patents

Protilátka, imunokonjugát, izolovaná nukleová kyselina, vektor, hostitelská bunka, zpusob výroby protilátky a farmaceutický prostredek ji obsahující Download PDF

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Publication number
CZ299702B6
CZ299702B6 CZ20014596A CZ20014596A CZ299702B6 CZ 299702 B6 CZ299702 B6 CZ 299702B6 CZ 20014596 A CZ20014596 A CZ 20014596A CZ 20014596 A CZ20014596 A CZ 20014596A CZ 299702 B6 CZ299702 B6 CZ 299702B6
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CZ
Czechia
Prior art keywords
antibody
cells
antibodies
cancer
erbb2
Prior art date
Application number
CZ20014596A
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Czech (cs)
English (en)
Other versions
CZ20014596A3 (cs
Inventor
W. Adams@Camellia
G. Presta@Leonard
Sliwkowsky@Mark
Original Assignee
Genentech Inc.
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Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22495168&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CZ299702(B6) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genentech Inc. filed Critical Genentech Inc.
Publication of CZ20014596A3 publication Critical patent/CZ20014596A3/cs
Publication of CZ299702B6 publication Critical patent/CZ299702B6/cs

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/32—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
    • A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
    • A61K47/6807—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug or compound being a sugar, nucleoside, nucleotide, nucleic acid, e.g. RNA antisense
    • A61K47/6809—Antibiotics, e.g. antitumor antibiotics anthracyclins, adriamycin, doxorubicin or daunomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A61K2039/507—Comprising a combination of two or more separate antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Packages (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CZ20014596A 1999-06-25 2000-06-23 Protilátka, imunokonjugát, izolovaná nukleová kyselina, vektor, hostitelská bunka, zpusob výroby protilátky a farmaceutický prostredek ji obsahující CZ299702B6 (cs)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US14131699P 1999-06-25 1999-06-25

Publications (2)

Publication Number Publication Date
CZ20014596A3 CZ20014596A3 (cs) 2003-02-12
CZ299702B6 true CZ299702B6 (cs) 2008-10-22

Family

ID=22495168

Family Applications (1)

Application Number Title Priority Date Filing Date
CZ20014596A CZ299702B6 (cs) 1999-06-25 2000-06-23 Protilátka, imunokonjugát, izolovaná nukleová kyselina, vektor, hostitelská bunka, zpusob výroby protilátky a farmaceutický prostredek ji obsahující

Country Status (32)

Country Link
EP (2) EP2112167A3 (OSRAM)
JP (2) JP4283474B2 (OSRAM)
KR (2) KR100850389B1 (OSRAM)
CN (4) CN101121750A (OSRAM)
AR (1) AR024464A1 (OSRAM)
AT (2) AT500848B1 (OSRAM)
AU (2) AU784045B2 (OSRAM)
BE (1) BE2013C020I2 (OSRAM)
BR (2) BR122014028365B8 (OSRAM)
CA (2) CA2727172A1 (OSRAM)
CH (1) CH694589A5 (OSRAM)
CY (2) CY1109525T1 (OSRAM)
CZ (1) CZ299702B6 (OSRAM)
DE (2) DE10084743T1 (OSRAM)
DK (1) DK1189641T5 (OSRAM)
ES (1) ES2329437T3 (OSRAM)
FR (1) FR13C0016I2 (OSRAM)
GB (1) GB2368796B (OSRAM)
GE (1) GEP20104998B (OSRAM)
HU (1) HU226742B1 (OSRAM)
IL (3) IL146954A0 (OSRAM)
LU (1) LU92164I2 (OSRAM)
MX (1) MXPA01013458A (OSRAM)
NO (3) NO328377B1 (OSRAM)
NZ (2) NZ516830A (OSRAM)
PL (2) PL203326B1 (OSRAM)
PT (1) PT1189641E (OSRAM)
RU (2) RU2270029C2 (OSRAM)
SI (3) SI2283867T1 (OSRAM)
TR (1) TR200103756T2 (OSRAM)
WO (1) WO2001000245A2 (OSRAM)
ZA (2) ZA200109786B (OSRAM)

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