ZA200508280B - Pharmaceutical compositions comprising bispecific anti-CD3, Anti-CD19 antibody constructs for the treatment of B-cell related disorders - Google Patents
Pharmaceutical compositions comprising bispecific anti-CD3, Anti-CD19 antibody constructs for the treatment of B-cell related disorders Download PDFInfo
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- ZA200508280B ZA200508280B ZA200508280A ZA200508280A ZA200508280B ZA 200508280 B ZA200508280 B ZA 200508280B ZA 200508280 A ZA200508280 A ZA 200508280A ZA 200508280 A ZA200508280 A ZA 200508280A ZA 200508280 B ZA200508280 B ZA 200508280B
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Classifications
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
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- Immunology (AREA)
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- Molecular Biology (AREA)
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- Biophysics (AREA)
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- Pain & Pain Management (AREA)
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- Transplantation (AREA)
- Hematology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP03012136 | 2003-05-31 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200508280B true ZA200508280B (en) | 2007-04-25 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200508280A ZA200508280B (en) | 2003-05-31 | 2005-10-13 | Pharmaceutical compositions comprising bispecific anti-CD3, Anti-CD19 antibody constructs for the treatment of B-cell related disorders |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US7635472B2 (OSRAM) |
| EP (1) | EP1629012B1 (OSRAM) |
| JP (3) | JP2008501621A (OSRAM) |
| CN (1) | CN100509850C (OSRAM) |
| AU (1) | AU2004242846A1 (OSRAM) |
| CA (1) | CA2522586C (OSRAM) |
| RU (1) | RU2005141512A (OSRAM) |
| WO (1) | WO2004106381A1 (OSRAM) |
| ZA (1) | ZA200508280B (OSRAM) |
Families Citing this family (370)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999054440A1 (en) * | 1998-04-21 | 1999-10-28 | Micromet Gesellschaft Für Biomedizinische Forschung Mbh | CD19xCD3 SPECIFIC POLYPEPTIDES AND USES THEREOF |
| JP3425536B2 (ja) | 1999-04-21 | 2003-07-14 | 株式会社チップトン | コーティング装置 |
| US20080260731A1 (en) * | 2002-03-01 | 2008-10-23 | Bernett Matthew J | Optimized antibodies that target cd19 |
| US9453251B2 (en) | 2002-10-08 | 2016-09-27 | Pfenex Inc. | Expression of mammalian proteins in Pseudomonas fluorescens |
| DE10254601A1 (de) | 2002-11-22 | 2004-06-03 | Ganymed Pharmaceuticals Ag | Differentiell in Tumoren exprimierte Genprodukte und deren Verwendung |
| EP2292664B1 (en) * | 2003-10-16 | 2016-11-23 | Amgen Research (Munich) GmbH | Multispecific deimmunized CD3-binders |
| DE602005022830D1 (de) * | 2004-02-16 | 2010-09-23 | Micromet Ag | Weniger immunogene bindungsmoleküle |
| EP2412816B1 (en) | 2004-07-26 | 2014-12-03 | Pfenex Inc. | Process for improved protein expression by strain engineering |
| DK1874821T3 (da) | 2005-04-26 | 2013-07-08 | Trion Pharma Gmbh | Kombination af antistoffer med glykokortikoider til behandling af kræft |
| BRPI0611714A2 (pt) | 2005-06-30 | 2009-01-13 | Abbott Lab | proteÍnas de ligaÇço a il-12/p40 |
| EP3770174A1 (en) | 2005-10-11 | 2021-01-27 | Amgen Research (Munich) GmbH | Compositions comprising cross-species-specific antibodies and uses thereof |
| AU2006326727A1 (en) | 2005-12-16 | 2007-06-21 | Amgen Research (Munich) Gmbh | Means and methods for the treatment of tumorous diseases |
| AU2013202375B2 (en) * | 2005-12-16 | 2016-10-27 | Amgen Research (Munich) Gmbh | Means and Methods for the Treatment of Tumorous Diseases |
| HRP20140331T1 (hr) | 2006-08-14 | 2014-05-09 | Xencor, Inc. | Optimizirana antitijela usmjerena na cd19 |
| MX2009002414A (es) * | 2006-09-08 | 2009-05-20 | Medimmune Llc | Anticuerpos anti-cd19 humanizados y su uso en el tratamiento de oncologia, transplante y enfermedad autoinmunitaria. |
| KR101625961B1 (ko) | 2006-09-08 | 2016-05-31 | 애브비 바하마스 리미티드 | 인터루킨-13 결합 단백질 |
| CA2685326A1 (en) | 2007-04-27 | 2008-11-06 | Dow Global Technologies Inc. | Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins |
| US9580719B2 (en) | 2007-04-27 | 2017-02-28 | Pfenex, Inc. | Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins |
| EP2014680A1 (en) * | 2007-07-10 | 2009-01-14 | Friedrich-Alexander-Universität Erlangen-Nürnberg | Recombinant, single-chain, trivalent tri-specific or bi-specific antibody derivatives |
| PT2211904T (pt) * | 2007-10-19 | 2016-11-02 | Seattle Genetics Inc | Agentes de ligação a cd19 e seus usos |
| EP2225275A4 (en) * | 2007-11-28 | 2013-04-03 | Medimmune Llc | PROTEIN FORMULATION |
| US20100260668A1 (en) * | 2008-04-29 | 2010-10-14 | Abbott Laboratories | Dual Variable Domain Immunoglobulins and Uses Thereof |
| EP2899209A1 (en) * | 2008-04-29 | 2015-07-29 | Abbvie Inc. | Dual Variable Domain Immunoglobulins and uses thereof |
| BRPI0913406A2 (pt) | 2008-06-03 | 2018-01-09 | Abbott Lab | imunoglobulinas de domínio variável duplo e usos das mesmas |
| EP2297208A4 (en) * | 2008-06-03 | 2012-07-11 | Abbott Lab | DUAL VARIABLE DOMAIN IMMUNOGLOBULINS AND ITS USES |
| US8822645B2 (en) * | 2008-07-08 | 2014-09-02 | Abbvie Inc. | Prostaglandin E2 dual variable domain immunoglobulins and uses thereof |
| JP5675608B2 (ja) | 2008-07-18 | 2015-02-25 | ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ | Ｃｄ２８結合のための一価組成物および使用方法 |
| DK2356153T3 (en) * | 2008-10-01 | 2016-07-04 | Amgen Res Munich Gmbh | Bispecific single CHAIN PSMAXCD3 ANTIBODY THAT ARE SPECIFICALLY TO ALL SPECIES |
| CA2738566C (en) | 2008-10-01 | 2024-04-30 | Micromet Ag | Bispecific single chain antibodies with specificity for high molecular weight target antigens |
| EP2352765B1 (en) | 2008-10-01 | 2018-01-03 | Amgen Research (Munich) GmbH | Cross-species-specific single domain bispecific single chain antibody |
| BRPI0919840B1 (pt) * | 2008-10-01 | 2023-02-28 | Amgen Research (Munich) Gmbh | Molécula de anticorpo de cadeia única biespecífica, seu uso, e composição farmacêutica que a compreende |
| US20110262440A1 (en) | 2008-11-07 | 2011-10-27 | Micromet Ag | Treatment of pediatric acute lymphoblastic leukemia |
| CA2742249C (en) * | 2008-11-07 | 2020-07-21 | Micromet Ag | Treatment of acute lymphoblastic leukemia with a cd19xcd3 bispecific single chain antibody |
| TW201109438A (en) * | 2009-07-29 | 2011-03-16 | Abbott Lab | Dual variable domain immunoglobulins and uses thereof |
| RU2012112550A (ru) * | 2009-09-01 | 2013-10-10 | Эбботт Лэборетриз | Иммуноглобулины с двумя вариабельными доменами и их применение |
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2004
- 2004-05-26 RU RU2005141512/13A patent/RU2005141512A/ru unknown
- 2004-05-26 JP JP2006529929A patent/JP2008501621A/ja not_active Withdrawn
- 2004-05-26 CA CA2522586A patent/CA2522586C/en not_active Expired - Lifetime
- 2004-05-26 AU AU2004242846A patent/AU2004242846A1/en not_active Abandoned
- 2004-05-26 WO PCT/EP2004/005685 patent/WO2004106381A1/en not_active Ceased
- 2004-05-26 CN CNB2004800145132A patent/CN100509850C/zh not_active Expired - Lifetime
- 2004-05-26 EP EP04739378.0A patent/EP1629012B1/en not_active Expired - Lifetime
- 2004-05-26 US US10/554,852 patent/US7635472B2/en not_active Expired - Lifetime
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2005
- 2005-10-13 ZA ZA200508280A patent/ZA200508280B/en unknown
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2012
- 2012-10-26 JP JP2012236443A patent/JP6025502B2/ja not_active Expired - Lifetime
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2015
- 2015-02-02 JP JP2015018323A patent/JP2015110628A/ja active Pending
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|---|---|
| CN1795208A (zh) | 2006-06-28 |
| US20070123479A1 (en) | 2007-05-31 |
| JP2013063981A (ja) | 2013-04-11 |
| CA2522586A1 (en) | 2004-12-09 |
| CA2522586C (en) | 2017-02-21 |
| CN100509850C (zh) | 2009-07-08 |
| JP6025502B2 (ja) | 2016-11-16 |
| US7635472B2 (en) | 2009-12-22 |
| EP1629012A1 (en) | 2006-03-01 |
| WO2004106381A1 (en) | 2004-12-09 |
| EP1629012B1 (en) | 2018-11-28 |
| JP2008501621A (ja) | 2008-01-24 |
| RU2005141512A (ru) | 2007-07-20 |
| JP2015110628A (ja) | 2015-06-18 |
| AU2004242846A1 (en) | 2004-12-09 |
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