UA80093C2 - Способ оптического разделения (1-бензил-4-метилпиперидин-3-ил)метиламина и его использование для получения производных пирроло[2, 3-d]пиримидина как ингибиторов протеинкиназы - Google Patents
Способ оптического разделения (1-бензил-4-метилпиперидин-3-ил)метиламина и его использование для получения производных пирроло[2, 3-d]пиримидина как ингибиторов протеинкиназы Download PDFInfo
- Publication number
- UA80093C2 UA80093C2 UA20031110841A UA20031110841A UA80093C2 UA 80093 C2 UA80093 C2 UA 80093C2 UA 20031110841 A UA20031110841 A UA 20031110841A UA 20031110841 A UA20031110841 A UA 20031110841A UA 80093 C2 UA80093 C2 UA 80093C2
- Authority
- UA
- Ukraine
- Prior art keywords
- alkyl
- amino
- alkylamino
- trifluoromethyl
- cyano
- Prior art date
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- 229940083082 pyrimidine derivative acting on arteriolar smooth muscle Drugs 0.000 title 1
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- 125000000217 alkyl group Chemical group 0.000 claims description 354
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims description 90
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- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 claims description 40
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- 125000004356 hydroxy functional group Chemical group O* 0.000 claims description 31
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- 125000001072 heteroaryl group Chemical group 0.000 claims description 22
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Classifications
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
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US29477501P | 2001-05-31 | 2001-05-31 | |
US34104801P | 2001-12-06 | 2001-12-06 | |
PCT/IB2002/001905 WO2002096909A1 (en) | 2001-05-31 | 2002-05-29 | Optical resolution of (1-benzyl-4-methylpiperidin-3-yl) -methylamine and the use thereof for the preparation of pyrrolo 2,3-pyrimidine derivatives as protein kinases inhibitors |
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UA20031110841A UA80093C2 (ru) | 2001-05-31 | 2002-05-29 | Способ оптического разделения (1-бензил-4-метилпиперидин-3-ил)метиламина и его использование для получения производных пирроло[2, 3-d]пиримидина как ингибиторов протеинкиназы |
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