UA74360C2 - Кристалічна основа циталопраму - Google Patents

Кристалічна основа циталопраму

Info

Publication number
UA74360C2
UA74360C2 UA2002097314A UA200297314A UA74360C2 UA 74360 C2 UA74360 C2 UA 74360C2 UA 2002097314 A UA2002097314 A UA 2002097314A UA 200297314 A UA200297314 A UA 200297314A UA 74360 C2 UA74360 C2 UA 74360C2
Authority
UA
Ukraine
Prior art keywords
citalopram
base
crystalline base
salts
formulations
Prior art date
Application number
UA2002097314A
Other languages
English (en)
Russian (ru)
Inventor
Ханс Петерсен
Клаус Петер Бьогесьо
Пер Холм
Original Assignee
Х. Луннбек А/С
X. Луннбек A/C
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8159320&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UA74360(C2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Х. Луннбек А/С, X. Луннбек A/C filed Critical Х. Луннбек А/С
Publication of UA74360C2 publication Critical patent/UA74360C2/uk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Laminated Bodies (AREA)
  • Silicates, Zeolites, And Molecular Sieves (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Manufacture Of Macromolecular Shaped Articles (AREA)

Abstract

Цей винахід відноситься до кристалічної основи добре відомого антидепресивного лікарського засобу циталопраму, 1-[3-(диметиламіно)пропіл]-1-(4-фторфеніл)-1,3-дигідро-5-ізобензофуранкарбонітрилу, препаратів із зазначеною основою, способу одержання очищених солей циталопраму, таких як гідробромід, з використанням основи, до солей, одержаних за зазначеним способом, і до препаратів, які містять зазначені солі.
UA2002097314A 2000-03-13 2001-02-28 Кристалічна основа циталопраму UA74360C2 (uk)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA200000402 2000-03-13
DKPCT/DK00/00183 2000-04-13
PCT/DK2001/000137 WO2001068627A1 (en) 2000-03-13 2001-02-28 Crystalline base of citalopram

Publications (1)

Publication Number Publication Date
UA74360C2 true UA74360C2 (uk) 2005-12-15

Family

ID=8159320

Family Applications (1)

Application Number Title Priority Date Filing Date
UA2002097314A UA74360C2 (uk) 2000-03-13 2001-02-28 Кристалічна основа циталопраму

Country Status (42)

Country Link
US (7) US20010031784A1 (uk)
EP (2) EP1169314B2 (uk)
JP (1) JP2003527383A (uk)
KR (1) KR20020080486A (uk)
CN (2) CN1680350A (uk)
AR (1) AR029811A1 (uk)
AT (3) ATE223396T1 (uk)
AU (2) AU746664B2 (uk)
BE (1) BE1013210A3 (uk)
BG (1) BG107065A (uk)
BR (1) BR0109373A (uk)
CA (2) CA2360287C (uk)
CH (2) CH691477A5 (uk)
CZ (1) CZ292077B6 (uk)
DE (7) DE20007303U1 (uk)
DK (3) DK173903B1 (uk)
EA (1) EA200200972A1 (uk)
ES (3) ES2180471T3 (uk)
FI (2) FI20010156A0 (uk)
FR (1) FR2806086B1 (uk)
GB (2) GB2357762B (uk)
GR (1) GR1003796B (uk)
HK (1) HK1054750A1 (uk)
HR (1) HRP20020756A2 (uk)
HU (3) HU0001581D0 (uk)
IE (1) IES20010109A2 (uk)
IL (2) IL147339A (uk)
IS (1) IS5841A (uk)
IT (2) IT1319645B1 (uk)
MX (1) MXPA02008793A (uk)
NL (2) NL1016435C1 (uk)
NO (2) NO312031B1 (uk)
PL (1) PL360158A1 (uk)
PT (2) PT1227088E (uk)
SE (2) SE517136C2 (uk)
SI (2) SI1169314T2 (uk)
SK (1) SK285528B6 (uk)
TR (1) TR200202185T2 (uk)
UA (1) UA74360C2 (uk)
WO (1) WO2001068627A1 (uk)
YU (1) YU68802A (uk)
ZA (1) ZA200207148B (uk)

Families Citing this family (61)

* Cited by examiner, † Cited by third party
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ATE237604T1 (de) 1999-04-14 2003-05-15 Lundbeck & Co As H Verfahren zur herstellung von citalopram
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US6299622B1 (en) 1999-08-19 2001-10-09 Fox Hollow Technologies, Inc. Atherectomy catheter with aligned imager
US8328829B2 (en) 1999-08-19 2012-12-11 Covidien Lp High capacity debulking catheter with razor edge cutting window
US7708749B2 (en) 2000-12-20 2010-05-04 Fox Hollow Technologies, Inc. Debulking catheters and methods
US7887556B2 (en) 2000-12-20 2011-02-15 Fox Hollow Technologies, Inc. Debulking catheters and methods
US7713279B2 (en) 2000-12-20 2010-05-11 Fox Hollow Technologies, Inc. Method and devices for cutting tissue
US7771444B2 (en) 2000-12-20 2010-08-10 Fox Hollow Technologies, Inc. Methods and devices for removing material from a body lumen
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IES20010206A2 (en) 2000-03-13 2002-03-06 Lundbeck & Co As H Method for the preparation of citalopram
GB2357762B (en) * 2000-03-13 2002-01-30 Lundbeck & Co As H Crystalline base of citalopram
US6977306B2 (en) 2000-05-02 2005-12-20 Sumitomo Chemical Company, Limited Citalopram hydrobromide crystal and method for crystallization thereof
AR032455A1 (es) 2000-05-12 2003-11-12 Lundbeck & Co As H Metodo para la preparacion de citalopram, un intermediario empleado en el metodo, un metodo para la preparacion del intermediario empleado en el metodo y composicion farmaceutica antidepresiva
IS6021A (is) * 2000-08-10 2001-10-20 H. Lundbeck A/S Lyfjasamsetningar sem innihalda sítalópram
GB2376233B (en) * 2000-08-10 2003-09-10 Lundbeck & Co As H Crystals of a pharmaceutically acceptable salt of citalopram wherein the median size of the crystals is at least 40 microns
EA003581B1 (ru) * 2000-12-22 2003-06-26 Х.Лундбекк А/С Способ получения чистого циталопрама
AU2001100195B4 (en) * 2001-01-05 2001-12-20 H Lundbeck As Pharmaceutical composition containing citalopram.
GB0105627D0 (en) * 2001-03-07 2001-04-25 Cipla Ltd Preparation of phthalanes
EA200301195A1 (ru) * 2001-05-01 2004-04-29 Х. Лундбекк А/С Применение энантиомерно чистого эсциталопрама
EA006213B1 (ru) 2001-07-31 2005-10-27 Х. Лундбекк А/С Кристаллическая композиция, содержащая эсциталопрам
US7148364B2 (en) * 2002-01-07 2006-12-12 Sun Pharmaceutical Industries Process for the preparation of 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofuran carbonitrile
GB2385848A (en) * 2002-02-27 2003-09-03 Cipla Ltd Citalopram salts
GB2386118A (en) * 2002-02-27 2003-09-10 Cipla Ltd Citalopram
GB2386119A (en) * 2002-02-27 2003-09-10 Cipla Ltd Purification of citalopram
GB0204607D0 (en) * 2002-02-27 2002-04-10 Matrix Lab Ltd Process
GB2387596B (en) * 2002-02-27 2004-02-11 Matrix Lab Ltd Process
GB0206708D0 (en) * 2002-03-21 2002-05-01 Cipla Ltd Pharmaceutical salts
EP1346989A1 (en) * 2002-03-21 2003-09-24 Jubilant Organosys Limited Improved process for the preparation of citalopram and its hydrobromide
US6812355B2 (en) 2002-10-22 2004-11-02 Sekhsaria Chemicals Limited Process for the manufacture of citalopram hydrobromide from 5-bromophthalide
US20050154052A1 (en) * 2003-03-24 2005-07-14 Hetero Drugs Limited Novel crystalline forms of (s)-citalopram oxalate
AU2003238676A1 (en) * 2003-04-21 2004-11-19 Podile Khadgapathi An improved process for the preparation of citalopram hydrobromide
US8246640B2 (en) 2003-04-22 2012-08-21 Tyco Healthcare Group Lp Methods and devices for cutting tissue at a vascular location
EP1486492A3 (en) * 2003-06-10 2005-02-23 Sun Pharmaceuticals Industries Ltd. A process for hydrogenolysis of [1-(3-dimethylamino)propyl)]-1-(4-fluorophenyl)-1,3-dihydro-5-halo-isobenzofuran.
GB0317475D0 (en) * 2003-07-25 2003-08-27 Meditab Specialities Pvt Ltd Product
JP4025735B2 (ja) * 2003-08-21 2007-12-26 ローム アンド ハース カンパニー 水性系を処理する方法
GB0320312D0 (en) 2003-08-29 2003-10-01 Novartis Ag Purification process
CN100569765C (zh) 2003-12-19 2009-12-16 杭州民生药业集团有限公司 西酞普兰中间体晶体碱
ITTO20050301A1 (it) * 2005-05-05 2006-11-06 Errekappa Euroterapici Spa Formulazioni liquide orali contenenti citalopram
WO2006123243A2 (en) * 2005-05-20 2006-11-23 Aurobindo Pharma Limited Pharmaceutical dosage forms comprising escitalopram in form of granules
US7834201B2 (en) 2005-06-22 2010-11-16 H. Lundbeck A/S Crystalline base of escitalopram and orodispersible tablets comprising escitalopram base
TWI358407B (en) * 2005-06-22 2012-02-21 Lundbeck & Co As H Crystalline base of escitalopram and orodispersibl
EP1896002A4 (en) 2005-06-27 2009-11-25 Biovail Lab Int Srl BUPROPIONAL SALT FORMULATIONS WITH MODIFIED RELEASE
US20070276419A1 (en) 2006-05-26 2007-11-29 Fox Hollow Technologies, Inc. Methods and devices for rotating an active element and an energy emitter on a catheter
US8784440B2 (en) 2008-02-25 2014-07-22 Covidien Lp Methods and devices for cutting tissue
US8414604B2 (en) 2008-10-13 2013-04-09 Covidien Lp Devices and methods for manipulating a catheter shaft
ES2532407T3 (es) 2009-04-29 2015-03-26 Covidien Lp Dispositivos para cortar y raspar tejido
CN102458276B (zh) 2009-05-14 2014-05-21 泰科保健集团有限合伙公司 粥样斑块切除导管
BR112012013389A2 (pt) 2009-12-02 2018-03-06 Tyco Healthcare métodos e dispositivos para o corte de um tecido
WO2011072149A1 (en) 2009-12-11 2011-06-16 Fox Hollow Technologies, Inc. Material removal device having improved material capture efficiency and methods of use
BR112012031907A2 (pt) 2010-06-14 2020-08-04 Covidien Lp dispositivo de remoção de material.
JP5636114B2 (ja) 2010-10-28 2014-12-03 コヴィディエン リミテッド パートナーシップ 物質除去デバイスおよび使用方法
WO2012064966A2 (en) 2010-11-11 2012-05-18 Tyco Healthcare Group Lp Flexible debulking catheters with imaging and methods of use and manufacture
US8992717B2 (en) 2011-09-01 2015-03-31 Covidien Lp Catheter with helical drive shaft and methods of manufacture
US9579157B2 (en) 2012-09-13 2017-02-28 Covidien Lp Cleaning device for medical instrument and method of use
US9943329B2 (en) 2012-11-08 2018-04-17 Covidien Lp Tissue-removing catheter with rotatable cutter
WO2015200702A1 (en) 2014-06-27 2015-12-30 Covidien Lp Cleaning device for catheter and catheter including the same
US10314667B2 (en) 2015-03-25 2019-06-11 Covidien Lp Cleaning device for cleaning medical instrument
US10292721B2 (en) 2015-07-20 2019-05-21 Covidien Lp Tissue-removing catheter including movable distal tip
US10314664B2 (en) 2015-10-07 2019-06-11 Covidien Lp Tissue-removing catheter and tissue-removing element with depth stop
WO2021016112A2 (en) 2019-07-19 2021-01-28 Bioxcel Therapeutics, Inc. Non-sedating dexmedetomidine treatment regimens
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UA62985C2 (en) * 1997-11-10 2004-01-15 Lunnbeck As H A method for the preparation of citalopram
EA002770B1 (ru) * 1997-11-11 2002-08-29 Х.Лундбекк А/С Способ получения циталопрама
KR100411505B1 (ko) 1998-10-20 2003-12-18 하. 룬트벡 아크티에 셀스카브 시탈로프람의 제조방법
ATE237604T1 (de) 1999-04-14 2003-05-15 Lundbeck & Co As H Verfahren zur herstellung von citalopram
ITMI991581A1 (it) 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
ITMI991579A1 (it) * 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
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GB2357762B (en) * 2000-03-13 2002-01-30 Lundbeck & Co As H Crystalline base of citalopram
US6977306B2 (en) * 2000-05-02 2005-12-20 Sumitomo Chemical Company, Limited Citalopram hydrobromide crystal and method for crystallization thereof

Also Published As

Publication number Publication date
ES2180471T3 (es) 2004-05-01
BE1013210A3 (fr) 2001-10-02
GB2357762A (en) 2001-07-04
PT1227088E (pt) 2003-12-31
ATE223396T1 (de) 2002-09-15
CZ292077B6 (cs) 2003-07-16
CN1429220A (zh) 2003-07-09
ATE250050T1 (de) 2003-10-15
PL360158A1 (en) 2004-09-06
GB0102797D0 (en) 2001-03-21
IT1319645B1 (it) 2003-10-23
IL147339A0 (en) 2002-08-14
EA200200972A1 (ru) 2003-02-27
DK1227088T3 (da) 2003-12-22
US20060247451A1 (en) 2006-11-02
NL1017413C1 (nl) 2001-09-13
GR1003796B (el) 2002-02-08
US20040167210A1 (en) 2004-08-26
US20040132808A1 (en) 2004-07-08
DE20121240U1 (de) 2002-07-04
CZ2001808A3 (cs) 2002-01-16
SI1227088T1 (en) 2003-12-31
IL158072A0 (en) 2004-03-28
IL147339A (en) 2004-09-27
ITMI20002425A1 (it) 2002-05-09
DE60100786D1 (de) 2003-10-23
US20030078442A1 (en) 2003-04-24
SE0103046L (sv) 2001-11-14
SE0200730L (sv) 2002-08-29
DE20007303U1 (de) 2000-07-27
CN1258530C (zh) 2006-06-07
CA2360287A1 (en) 2001-09-20
DE60100022T3 (de) 2011-11-17
CN1680350A (zh) 2005-10-12
SE526022C2 (sv) 2005-06-14
ES2173054T3 (es) 2002-12-16
DE60100022D1 (de) 2002-10-10
DK1169314T3 (da) 2002-10-14
NL1016435C1 (nl) 2000-11-06
DE10164687B4 (de) 2006-04-27
NO312031B1 (no) 2002-03-04
SI1169314T2 (sl) 2011-08-31
SE0200730D0 (sv) 2002-03-12
EP1227088A1 (en) 2002-07-31
ZA200207148B (en) 2003-04-23
US20050165092A1 (en) 2005-07-28
CA2411732A1 (en) 2001-09-20
AU2001100197B4 (en) 2001-12-06
SI1169314T1 (en) 2002-12-31
AU746664B2 (en) 2002-05-02
AR029811A1 (es) 2003-07-16
DE1227088T1 (de) 2003-02-06
HU0001581D0 (en) 2000-06-28
HRP20020756A2 (en) 2004-12-31
ES2159491A1 (es) 2001-10-01
SE0103046D0 (sv) 2001-09-14
FI20010156A0 (fi) 2001-01-25
BR0109373A (pt) 2002-12-24
SK285528B6 (sk) 2007-03-01
FR2806086B1 (fr) 2003-05-09
HU0100531D0 (en) 2001-03-28
DE60100786T2 (de) 2004-07-15
NO20010619D0 (no) 2001-02-06
TR200202185T2 (tr) 2002-12-23
NO20020356L (no) 2001-09-14
JP2003527383A (ja) 2003-09-16
FI20010225A0 (fi) 2001-02-07
FI20010225A (fi) 2001-09-14
GB0105982D0 (en) 2001-05-02
SK13132002A3 (sk) 2003-01-09
CH691477A5 (de) 2001-07-31
NO315851B1 (no) 2003-11-03
WO2001068627A1 (en) 2001-09-20
DK173903B1 (da) 2002-02-11
US20050165244A1 (en) 2005-07-28
EP1169314A1 (en) 2002-01-09
NO20010619L (no) 2001-09-14
SE517136C2 (sv) 2002-04-16
FR2806086A1 (fr) 2001-09-14
EP1227088B1 (en) 2003-09-17
ITMI20010406A1 (it) 2002-08-28
CH691537A5 (de) 2001-08-15
EP1169314B2 (en) 2011-06-01
BG107065A (bg) 2003-05-30
KR20020080486A (ko) 2002-10-23
US20010031784A1 (en) 2001-10-18
IS5841A (is) 2001-09-14
ES2173054T1 (es) 2002-10-16
YU68802A (sh) 2005-11-28
DE10108042A1 (de) 2001-10-18
GB2357762B (en) 2002-01-30
PT1169314E (pt) 2002-11-29
FI109022B (fi) 2002-05-15
HUP0100531A3 (en) 2004-04-28
ES2180471T1 (es) 2003-02-16
DE60100022T2 (de) 2003-03-06
AT4364U1 (de) 2001-06-25
MXPA02008793A (es) 2003-02-12
CA2360287C (en) 2003-09-09
IES20010109A2 (en) 2002-02-20
EP1169314B1 (en) 2002-09-04
AU3725201A (en) 2001-09-13
NO20020356D0 (no) 2002-01-23
HU0100450D0 (en) 2001-04-28
AU2001100197A4 (en) 2001-09-20
HK1054750A1 (en) 2003-12-12
HUP0100531A2 (hu) 2002-01-28
ES2159491B1 (es) 2002-05-01

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