HUP0100531A2 - Citalopram kristályos bázisa, eljárás előállítására, és azt tartalmazó gyógyszerkészítmények - Google Patents

Citalopram kristályos bázisa, eljárás előállítására, és azt tartalmazó gyógyszerkészítmények

Info

Publication number
HUP0100531A2
HUP0100531A2 HU0100531A HUP0100531A HUP0100531A2 HU P0100531 A2 HUP0100531 A2 HU P0100531A2 HU 0100531 A HU0100531 A HU 0100531A HU P0100531 A HUP0100531 A HU P0100531A HU P0100531 A2 HUP0100531 A2 HU P0100531A2
Authority
HU
Hungary
Prior art keywords
citalopram
producing
same
base
medicament containing
Prior art date
Application number
HU0100531A
Other languages
English (en)
Inventor
Klaus Peter Bogeso
Per Holm
Hans Petersen
Original Assignee
H. Lundbeck A/S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8159320&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUP0100531(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by H. Lundbeck A/S filed Critical H. Lundbeck A/S
Publication of HU0100531D0 publication Critical patent/HU0100531D0/hu
Publication of HUP0100531A2 publication Critical patent/HUP0100531A2/hu
Publication of HUP0100531A3 publication Critical patent/HUP0100531A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Abstract

A találmány a jól ismert, citalopram nevű antidepresszáns hatóanyag(kémiai neve: 1-[3-(dimetilamino)propil]-1-(4-fluorfenil)-1,3-dihidro-5-izo-benzofuránkarbonitril) kristályos bázisára, ilyen bázisttartalmazó gyógyászati készítményekre, a citalopram tisztított sóinak,például hidrobromidjának előállítására, valamint a bázis és tisztítottsói alkalmazására vonatkozik. Ó
HU0100531A 2000-03-13 2001-02-05 Crystalline base of citalopram, method for producing it and medicament containing the same HUP0100531A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DKPA200000402 2000-03-13

Publications (3)

Publication Number Publication Date
HU0100531D0 HU0100531D0 (en) 2001-03-28
HUP0100531A2 true HUP0100531A2 (hu) 2002-01-28
HUP0100531A3 HUP0100531A3 (en) 2004-04-28

Family

ID=8159320

Family Applications (3)

Application Number Title Priority Date Filing Date
HU0001581A HU0001581D0 (en) 2000-03-13 2000-04-18 Crystalline base of citalopram
HU0100450A HU0100450D0 (en) 2000-03-13 2001-01-26 Crystalline base of citalopram
HU0100531A HUP0100531A3 (en) 2000-03-13 2001-02-05 Crystalline base of citalopram, method for producing it and medicament containing the same

Family Applications Before (2)

Application Number Title Priority Date Filing Date
HU0001581A HU0001581D0 (en) 2000-03-13 2000-04-18 Crystalline base of citalopram
HU0100450A HU0100450D0 (en) 2000-03-13 2001-01-26 Crystalline base of citalopram

Country Status (42)

Country Link
US (7) US20010031784A1 (hu)
EP (2) EP1227088B1 (hu)
JP (1) JP2003527383A (hu)
KR (1) KR20020080486A (hu)
CN (2) CN1258530C (hu)
AR (1) AR029811A1 (hu)
AT (3) ATE223396T1 (hu)
AU (2) AU746664B2 (hu)
BE (1) BE1013210A3 (hu)
BG (1) BG107065A (hu)
BR (1) BR0109373A (hu)
CA (2) CA2411732A1 (hu)
CH (2) CH691537A5 (hu)
CZ (1) CZ292077B6 (hu)
DE (7) DE20007303U1 (hu)
DK (3) DK173903B1 (hu)
EA (1) EA200200972A1 (hu)
ES (3) ES2173054T3 (hu)
FI (2) FI20010156A0 (hu)
FR (1) FR2806086B1 (hu)
GB (2) GB2357762B (hu)
GR (1) GR1003796B (hu)
HK (1) HK1054750A1 (hu)
HR (1) HRP20020756A2 (hu)
HU (3) HU0001581D0 (hu)
IE (1) IES20010109A2 (hu)
IL (2) IL158072A0 (hu)
IS (1) IS5841A (hu)
IT (2) IT1319645B1 (hu)
MX (1) MXPA02008793A (hu)
NL (2) NL1016435C1 (hu)
NO (2) NO312031B1 (hu)
PL (1) PL360158A1 (hu)
PT (2) PT1169314E (hu)
SE (2) SE517136C2 (hu)
SI (2) SI1169314T2 (hu)
SK (1) SK285528B6 (hu)
TR (1) TR200202185T2 (hu)
UA (1) UA74360C2 (hu)
WO (1) WO2001068627A1 (hu)
YU (1) YU68802A (hu)
ZA (1) ZA200207148B (hu)

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AR021155A1 (es) * 1999-07-08 2002-06-12 Lundbeck & Co As H Tratamiento de desordenes neuroticos
US7708749B2 (en) 2000-12-20 2010-05-04 Fox Hollow Technologies, Inc. Debulking catheters and methods
US8328829B2 (en) 1999-08-19 2012-12-11 Covidien Lp High capacity debulking catheter with razor edge cutting window
US7887556B2 (en) 2000-12-20 2011-02-15 Fox Hollow Technologies, Inc. Debulking catheters and methods
US6299622B1 (en) 1999-08-19 2001-10-09 Fox Hollow Technologies, Inc. Atherectomy catheter with aligned imager
US7713279B2 (en) 2000-12-20 2010-05-11 Fox Hollow Technologies, Inc. Method and devices for cutting tissue
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GB2357762B (en) * 2000-03-13 2002-01-30 Lundbeck & Co As H Crystalline base of citalopram
NL1017500C1 (nl) 2000-03-13 2001-04-26 Lundbeck & Co As H Werkwijze voor de bereiding van Citalopram.
US6977306B2 (en) 2000-05-02 2005-12-20 Sumitomo Chemical Company, Limited Citalopram hydrobromide crystal and method for crystallization thereof
AR032455A1 (es) 2000-05-12 2003-11-12 Lundbeck & Co As H Metodo para la preparacion de citalopram, un intermediario empleado en el metodo, un metodo para la preparacion del intermediario empleado en el metodo y composicion farmaceutica antidepresiva
GB2376233B (en) * 2000-08-10 2003-09-10 Lundbeck & Co As H Crystals of a pharmaceutically acceptable salt of citalopram wherein the median size of the crystals is at least 40 microns
IES20010693A2 (en) * 2000-08-10 2002-07-10 Lundbeck & Co As H Pharmaceutical composition containing citalopram
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AU2003222435A1 (en) * 2002-01-07 2003-07-24 Sun Pharmaceutical Industries Limited Process for the preparation of 1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)- 1,3-dihydro-5-isobenzofuran carbonitrile
GB2386119A (en) * 2002-02-27 2003-09-10 Cipla Ltd Purification of citalopram
GB2387844B (en) * 2002-02-27 2005-05-11 Matrix Lab Ltd Separation of impurities from a crude mixture of citalopram
GB2385848A (en) * 2002-02-27 2003-09-03 Cipla Ltd Citalopram salts
GB2386118A (en) * 2002-02-27 2003-09-10 Cipla Ltd Citalopram
GB0204607D0 (en) * 2002-02-27 2002-04-10 Matrix Lab Ltd Process
EP1346989A1 (en) * 2002-03-21 2003-09-24 Jubilant Organosys Limited Improved process for the preparation of citalopram and its hydrobromide
GB0206708D0 (en) * 2002-03-21 2002-05-01 Cipla Ltd Pharmaceutical salts
US6812355B2 (en) 2002-10-22 2004-11-02 Sekhsaria Chemicals Limited Process for the manufacture of citalopram hydrobromide from 5-bromophthalide
US20050154052A1 (en) * 2003-03-24 2005-07-14 Hetero Drugs Limited Novel crystalline forms of (s)-citalopram oxalate
AU2003238676A1 (en) * 2003-04-21 2004-11-19 Podile Khadgapathi An improved process for the preparation of citalopram hydrobromide
US8246640B2 (en) 2003-04-22 2012-08-21 Tyco Healthcare Group Lp Methods and devices for cutting tissue at a vascular location
US7019153B2 (en) 2003-06-10 2006-03-28 Sun Pharmaceutical Industries Limited Process for hydrogenolysis of [1-(3-dimethylamino)propyl)]-1-(4-fluorophenyl)-1,3-dihydro-5-halo-isobenzofuran acetamido-3-substituted-3-cephem-4-carboxylic acid
GB0317475D0 (en) 2003-07-25 2003-08-27 Meditab Specialities Pvt Ltd Product
JP4025735B2 (ja) * 2003-08-21 2007-12-26 ローム アンド ハース カンパニー 水性系を処理する方法
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CN100569765C (zh) * 2003-12-19 2009-12-16 杭州民生药业集团有限公司 西酞普兰中间体晶体碱
ITTO20050301A1 (it) * 2005-05-05 2006-11-06 Errekappa Euroterapici Spa Formulazioni liquide orali contenenti citalopram
US20110196032A1 (en) * 2005-05-20 2011-08-11 Ashish Gogia Pharmaceutical Dosage Form of an Antidepressant
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TWI347942B (en) * 2005-06-22 2011-09-01 Lundbeck & Co As H Crystalline base of escitalopram and orodispersible tablets comprising escitalopram base
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US8784440B2 (en) 2008-02-25 2014-07-22 Covidien Lp Methods and devices for cutting tissue
EP2358282B1 (en) 2008-10-13 2017-12-06 Covidien LP Devices for manipulating a catheter shaft
US9687266B2 (en) 2009-04-29 2017-06-27 Covidien Lp Methods and devices for cutting and abrading tissue
KR101323514B1 (ko) 2009-05-14 2013-10-29 코비디엔 엘피 세척이 용이한 죽상반 절제 카테터 및 사용 방법
CN102695462B (zh) 2009-12-02 2015-01-14 泰科保健集团有限合伙公司 用于切割组织的方法和装置
EP2509519B1 (en) 2009-12-11 2019-08-07 Covidien LP Material removal device having improved material capture efficiency
CA2800920C (en) 2010-06-14 2015-04-14 Covidien Lp Material removal device
CN103200886B (zh) 2010-10-28 2015-07-29 科维蒂恩有限合伙公司 物质移除装置和使用方法
AU2011326420B2 (en) 2010-11-11 2014-11-27 Covidien Lp Flexible debulking catheters with imaging and methods of use and manufacture
JP5806407B2 (ja) 2011-09-01 2015-11-10 コヴィディエン リミテッド パートナーシップ 螺旋駆動軸を有するカテーテルおよび製造方法
US9532844B2 (en) 2012-09-13 2017-01-03 Covidien Lp Cleaning device for medical instrument and method of use
US9943329B2 (en) 2012-11-08 2018-04-17 Covidien Lp Tissue-removing catheter with rotatable cutter
WO2015200702A1 (en) 2014-06-27 2015-12-30 Covidien Lp Cleaning device for catheter and catheter including the same
US10314667B2 (en) 2015-03-25 2019-06-11 Covidien Lp Cleaning device for cleaning medical instrument
US10292721B2 (en) 2015-07-20 2019-05-21 Covidien Lp Tissue-removing catheter including movable distal tip
US10314664B2 (en) 2015-10-07 2019-06-11 Covidien Lp Tissue-removing catheter and tissue-removing element with depth stop

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Also Published As

Publication number Publication date
YU68802A (sh) 2005-11-28
SE0200730D0 (sv) 2002-03-12
AT4364U1 (de) 2001-06-25
ES2180471T1 (es) 2003-02-16
DK173903B1 (da) 2002-02-11
EP1227088A1 (en) 2002-07-31
NO20010619L (no) 2001-09-14
HU0100450D0 (en) 2001-04-28
DE60100022T2 (de) 2003-03-06
CH691477A5 (de) 2001-07-31
CN1680350A (zh) 2005-10-12
DK1227088T3 (da) 2003-12-22
IT1319645B1 (it) 2003-10-23
FR2806086A1 (fr) 2001-09-14
IL158072A0 (en) 2004-03-28
BE1013210A3 (fr) 2001-10-02
CZ2001808A3 (cs) 2002-01-16
SK13132002A3 (sk) 2003-01-09
DE10108042A1 (de) 2001-10-18
SE0200730L (sv) 2002-08-29
AU2001100197A4 (en) 2001-09-20
NO312031B1 (no) 2002-03-04
FI20010225A0 (fi) 2001-02-07
KR20020080486A (ko) 2002-10-23
ZA200207148B (en) 2003-04-23
FR2806086B1 (fr) 2003-05-09
SI1169314T2 (sl) 2011-08-31
US20010031784A1 (en) 2001-10-18
SE0103046L (sv) 2001-11-14
ATE223396T1 (de) 2002-09-15
CZ292077B6 (cs) 2003-07-16
AR029811A1 (es) 2003-07-16
ITMI20010406A1 (it) 2002-08-28
NO315851B1 (no) 2003-11-03
WO2001068627A1 (en) 2001-09-20
ES2180471T3 (es) 2004-05-01
HK1054750A1 (en) 2003-12-12
US20040167210A1 (en) 2004-08-26
CH691537A5 (de) 2001-08-15
ATE250050T1 (de) 2003-10-15
US20060247451A1 (en) 2006-11-02
HU0001581D0 (en) 2000-06-28
GB2357762A (en) 2001-07-04
EP1227088B1 (en) 2003-09-17
DE20121240U1 (de) 2002-07-04
ITMI20002425A1 (it) 2002-05-09
SI1169314T1 (en) 2002-12-31
ES2173054T3 (es) 2002-12-16
SE526022C2 (sv) 2005-06-14
IL147339A0 (en) 2002-08-14
HUP0100531A3 (en) 2004-04-28
ES2173054T1 (es) 2002-10-16
BG107065A (bg) 2003-05-30
EP1169314A1 (en) 2002-01-09
DE60100022D1 (de) 2002-10-10
FI20010225A (fi) 2001-09-14
PT1169314E (pt) 2002-11-29
IES20010109A2 (en) 2002-02-20
SK285528B6 (sk) 2007-03-01
GB0105982D0 (en) 2001-05-02
MXPA02008793A (es) 2003-02-12
DK1169314T3 (da) 2002-10-14
EP1169314B1 (en) 2002-09-04
PT1227088E (pt) 2003-12-31
SE517136C2 (sv) 2002-04-16
DE60100022T3 (de) 2011-11-17
AU746664B2 (en) 2002-05-02
DE1227088T1 (de) 2003-02-06
CA2360287C (en) 2003-09-09
DE20007303U1 (de) 2000-07-27
AU2001100197B4 (en) 2001-12-06
CA2360287A1 (en) 2001-09-20
NO20010619D0 (no) 2001-02-06
UA74360C2 (uk) 2005-12-15
US20050165092A1 (en) 2005-07-28
GR1003796B (el) 2002-02-08
AU3725201A (en) 2001-09-13
US20030078442A1 (en) 2003-04-24
EA200200972A1 (ru) 2003-02-27
EP1169314B2 (en) 2011-06-01
GB0102797D0 (en) 2001-03-21
NO20020356L (no) 2001-09-14
PL360158A1 (en) 2004-09-06
NL1017413C1 (nl) 2001-09-13
HRP20020756A2 (en) 2004-12-31
US20040132808A1 (en) 2004-07-08
DE60100786D1 (de) 2003-10-23
IS5841A (is) 2001-09-14
CN1258530C (zh) 2006-06-07
ES2159491A1 (es) 2001-10-01
CN1429220A (zh) 2003-07-09
TR200202185T2 (tr) 2002-12-23
BR0109373A (pt) 2002-12-24
DE60100786T2 (de) 2004-07-15
US20050165244A1 (en) 2005-07-28
SE0103046D0 (sv) 2001-09-14
HU0100531D0 (en) 2001-03-28
SI1227088T1 (en) 2003-12-31
IL147339A (en) 2004-09-27
JP2003527383A (ja) 2003-09-16
FI109022B (fi) 2002-05-15
CA2411732A1 (en) 2001-09-20
FI20010156A0 (fi) 2001-01-25
DE10164687B4 (de) 2006-04-27
ES2159491B1 (es) 2002-05-01
NO20020356D0 (no) 2002-01-23
GB2357762B (en) 2002-01-30
NL1016435C1 (nl) 2000-11-06

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