ATE250050T1 - Kristalline base von citalopram, und hydrochlorid-oder hydrobromidsalz davon - Google Patents

Kristalline base von citalopram, und hydrochlorid-oder hydrobromidsalz davon

Info

Publication number
ATE250050T1
ATE250050T1 AT02009350T AT02009350T ATE250050T1 AT E250050 T1 ATE250050 T1 AT E250050T1 AT 02009350 T AT02009350 T AT 02009350T AT 02009350 T AT02009350 T AT 02009350T AT E250050 T1 ATE250050 T1 AT E250050T1
Authority
AT
Austria
Prior art keywords
citalopram
hydrochloride
hydrobromide salt
crystalline base
crystalline
Prior art date
Application number
AT02009350T
Other languages
English (en)
Inventor
Hans Petersen
Klaus Peter Boegesoe
Per Holm
Original Assignee
Lundbeck & Co As H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8159320&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE250050(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H
Application granted granted Critical
Publication of ATE250050T1 publication Critical patent/ATE250050T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Laminated Bodies (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Silicates, Zeolites, And Molecular Sieves (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Manufacture Of Macromolecular Shaped Articles (AREA)
AT02009350T 2000-03-13 2001-02-28 Kristalline base von citalopram, und hydrochlorid-oder hydrobromidsalz davon ATE250050T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200000402 2000-03-13
DKPCT/DK00/00183 2000-04-13

Publications (1)

Publication Number Publication Date
ATE250050T1 true ATE250050T1 (de) 2003-10-15

Family

ID=8159320

Family Applications (3)

Application Number Title Priority Date Filing Date
AT01909568T ATE223396T1 (de) 2000-03-13 2001-02-28 Kristalline base des citaloprams
AT02009350T ATE250050T1 (de) 2000-03-13 2001-02-28 Kristalline base von citalopram, und hydrochlorid-oder hydrobromidsalz davon
AT0016601U AT4364U1 (de) 2000-03-13 2001-03-07 Kristalline citalopram-base

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT01909568T ATE223396T1 (de) 2000-03-13 2001-02-28 Kristalline base des citaloprams

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT0016601U AT4364U1 (de) 2000-03-13 2001-03-07 Kristalline citalopram-base

Country Status (42)

Country Link
US (7) US20010031784A1 (de)
EP (2) EP1227088B1 (de)
JP (1) JP2003527383A (de)
KR (1) KR20020080486A (de)
CN (2) CN1680350A (de)
AR (1) AR029811A1 (de)
AT (3) ATE223396T1 (de)
AU (2) AU746664B2 (de)
BE (1) BE1013210A3 (de)
BG (1) BG107065A (de)
BR (1) BR0109373A (de)
CA (2) CA2360287C (de)
CH (2) CH691537A5 (de)
CZ (1) CZ292077B6 (de)
DE (7) DE20007303U1 (de)
DK (3) DK173903B1 (de)
EA (1) EA200200972A1 (de)
ES (3) ES2173054T3 (de)
FI (2) FI20010156A0 (de)
FR (1) FR2806086B1 (de)
GB (2) GB2357762B (de)
GR (1) GR1003796B (de)
HK (1) HK1054750A1 (de)
HR (1) HRP20020756A2 (de)
HU (3) HU0001581D0 (de)
IE (1) IES20010109A2 (de)
IL (2) IL158072A0 (de)
IS (1) IS5841A (de)
IT (2) IT1319645B1 (de)
MX (1) MXPA02008793A (de)
NL (2) NL1016435C1 (de)
NO (2) NO312031B1 (de)
PL (1) PL360158A1 (de)
PT (2) PT1227088E (de)
SE (2) SE517136C2 (de)
SI (2) SI1169314T2 (de)
SK (1) SK285528B6 (de)
TR (1) TR200202185T2 (de)
UA (1) UA74360C2 (de)
WO (1) WO2001068627A1 (de)
YU (1) YU68802A (de)
ZA (1) ZA200207148B (de)

Families Citing this family (61)

* Cited by examiner, † Cited by third party
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TR200102957T2 (tr) 1999-04-14 2004-12-21 H. Lundbeck A/S Sitalopram hazırlanması için metod.
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US6299622B1 (en) 1999-08-19 2001-10-09 Fox Hollow Technologies, Inc. Atherectomy catheter with aligned imager
US7887556B2 (en) 2000-12-20 2011-02-15 Fox Hollow Technologies, Inc. Debulking catheters and methods
US8328829B2 (en) 1999-08-19 2012-12-11 Covidien Lp High capacity debulking catheter with razor edge cutting window
US7708749B2 (en) 2000-12-20 2010-05-04 Fox Hollow Technologies, Inc. Debulking catheters and methods
US7713279B2 (en) 2000-12-20 2010-05-11 Fox Hollow Technologies, Inc. Method and devices for cutting tissue
IES20010157A2 (en) 2000-03-03 2002-03-06 Lundbeck & Co As H Method for the preparation of citalopram
GB2357762B (en) * 2000-03-13 2002-01-30 Lundbeck & Co As H Crystalline base of citalopram
NL1017500C1 (nl) 2000-03-13 2001-04-26 Lundbeck & Co As H Werkwijze voor de bereiding van Citalopram.
US6977306B2 (en) * 2000-05-02 2005-12-20 Sumitomo Chemical Company, Limited Citalopram hydrobromide crystal and method for crystallization thereof
AR032455A1 (es) 2000-05-12 2003-11-12 Lundbeck & Co As H Metodo para la preparacion de citalopram, un intermediario empleado en el metodo, un metodo para la preparacion del intermediario empleado en el metodo y composicion farmaceutica antidepresiva
GB2376233B (en) * 2000-08-10 2003-09-10 Lundbeck & Co As H Crystals of a pharmaceutically acceptable salt of citalopram wherein the median size of the crystals is at least 40 microns
CA2353693C (en) * 2000-08-10 2003-07-22 H. Lundbeck A/S Pharmaceutical composition containing citalopram
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HUP0400054A3 (en) * 2001-05-01 2007-03-28 Lundbeck & Co As H The use of enantiomeric pure escitalopram
DK1414435T3 (da) 2001-07-31 2005-05-09 Lundbeck & Co As H Krystallinsk komposition indeholdende escitalopram
AU2003222435A1 (en) * 2002-01-07 2003-07-24 Sun Pharmaceutical Industries Limited Process for the preparation of 1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)- 1,3-dihydro-5-isobenzofuran carbonitrile
GB2386118A (en) * 2002-02-27 2003-09-10 Cipla Ltd Citalopram
GB2386119A (en) * 2002-02-27 2003-09-10 Cipla Ltd Purification of citalopram
GB0204607D0 (en) * 2002-02-27 2002-04-10 Matrix Lab Ltd Process
GB2387596B (en) * 2002-02-27 2004-02-11 Matrix Lab Ltd Process
GB2385848A (en) * 2002-02-27 2003-09-03 Cipla Ltd Citalopram salts
EP1346989A1 (de) * 2002-03-21 2003-09-24 Jubilant Organosys Limited Verbessertes Verfahren zur Herstellung von Citalopram und Citalopram Hydrobromid
GB0206708D0 (en) * 2002-03-21 2002-05-01 Cipla Ltd Pharmaceutical salts
US6812355B2 (en) 2002-10-22 2004-11-02 Sekhsaria Chemicals Limited Process for the manufacture of citalopram hydrobromide from 5-bromophthalide
AU2003223105A1 (en) * 2003-03-24 2004-10-18 Hetero Drugs Limited Novel crystalline forms of (s)-citalopram oxalate
WO2004094399A1 (en) * 2003-04-21 2004-11-04 Natco Pharma Ltd An improved process for the preparation of citalopram hydrobromide
US8246640B2 (en) 2003-04-22 2012-08-21 Tyco Healthcare Group Lp Methods and devices for cutting tissue at a vascular location
EP1486492A3 (de) * 2003-06-10 2005-02-23 Sun Pharmaceuticals Industries Ltd. Ein Verfahren zur Hydrogenolyse von [1-(3-dimethylamino)propyl)]-1-(4-fluorophenyl)-1,3-dihydro-5-halo-isobenzofuran
GB0317475D0 (en) 2003-07-25 2003-08-27 Meditab Specialities Pvt Ltd Product
JP4025735B2 (ja) * 2003-08-21 2007-12-26 ローム アンド ハース カンパニー 水性系を処理する方法
GB0320312D0 (en) 2003-08-29 2003-10-01 Novartis Ag Purification process
CN100569765C (zh) * 2003-12-19 2009-12-16 杭州民生药业集团有限公司 西酞普兰中间体晶体碱
ITTO20050301A1 (it) * 2005-05-05 2006-11-06 Errekappa Euroterapici Spa Formulazioni liquide orali contenenti citalopram
US20110196032A1 (en) * 2005-05-20 2011-08-11 Ashish Gogia Pharmaceutical Dosage Form of an Antidepressant
US7834201B2 (en) 2005-06-22 2010-11-16 H. Lundbeck A/S Crystalline base of escitalopram and orodispersible tablets comprising escitalopram base
TWI347942B (en) * 2005-06-22 2011-09-01 Lundbeck & Co As H Crystalline base of escitalopram and orodispersible tablets comprising escitalopram base
KR101306635B1 (ko) 2005-06-27 2013-10-11 밸리언트 인터내셔널(바베이도스) 에스알엘 부프로피온염의 개질-방출 제형
US20070276419A1 (en) 2006-05-26 2007-11-29 Fox Hollow Technologies, Inc. Methods and devices for rotating an active element and an energy emitter on a catheter
US8784440B2 (en) 2008-02-25 2014-07-22 Covidien Lp Methods and devices for cutting tissue
WO2010045226A2 (en) 2008-10-13 2010-04-22 Fox Hollow Technologies, Inc. Devices and methods for manipulating a catheter shaft
RU2509537C2 (ru) 2009-04-29 2014-03-20 ТАЙКО ХЕЛСКЕА ГРУП эЛПи Способы и устройства для срезания и очищения ткани
CN102458276B (zh) 2009-05-14 2014-05-21 泰科保健集团有限合伙公司 粥样斑块切除导管
BR112012013389A2 (pt) 2009-12-02 2018-03-06 Tyco Healthcare métodos e dispositivos para o corte de um tecido
EP2509519B1 (de) 2009-12-11 2019-08-07 Covidien LP Materialentfernungsvorrichtung mit verbesserter materialerfassung
EP2579791B1 (de) 2010-06-14 2014-04-23 Covidien LP Materialentfernungsvorrichtung
EP2632352B1 (de) 2010-10-28 2017-04-12 Covidien LP Vorrichtung zur materialentfernung
CN103281964B (zh) 2010-11-11 2015-09-30 科维蒂恩有限合伙公司 具备成像能力的柔性减灭导管及制造导管的方法
WO2013033426A2 (en) 2011-09-01 2013-03-07 Covidien Lp Catheter with helical drive shaft and methods of manufacture
US9532844B2 (en) 2012-09-13 2017-01-03 Covidien Lp Cleaning device for medical instrument and method of use
US9943329B2 (en) 2012-11-08 2018-04-17 Covidien Lp Tissue-removing catheter with rotatable cutter
WO2015200702A1 (en) 2014-06-27 2015-12-30 Covidien Lp Cleaning device for catheter and catheter including the same
US10314667B2 (en) 2015-03-25 2019-06-11 Covidien Lp Cleaning device for cleaning medical instrument
US10292721B2 (en) 2015-07-20 2019-05-21 Covidien Lp Tissue-removing catheter including movable distal tip
US10314664B2 (en) 2015-10-07 2019-06-11 Covidien Lp Tissue-removing catheter and tissue-removing element with depth stop
KR20220049526A (ko) 2019-07-19 2022-04-21 바이오엑셀 테라퓨틱스 인코포레이티드 비-진정성 덱스메데토미딘 치료 양생법
US11806334B1 (en) 2023-01-12 2023-11-07 Bioxcel Therapeutics, Inc. Non-sedating dexmedetomidine treatment regimens

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IL133511A (en) * 1997-07-08 2004-05-12 Lundbeck & Co As H A method of preparing citalopram and pharmaceutical mixtures containing it
UA62985C2 (en) * 1997-11-10 2004-01-15 Lunnbeck As H A method for the preparation of citalopram
CZ292911B6 (cs) * 1997-11-11 2004-01-14 H. Lundbeck A/S Způsob výroby citalopramu
CZ299920B6 (cs) * 1998-10-20 2008-12-29 H. Lundbeck A/S Zpusob výroby citalopramu
TR200102957T2 (tr) 1999-04-14 2004-12-21 H. Lundbeck A/S Sitalopram hazırlanması için metod.
ITMI991581A1 (it) * 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
ITMI991579A1 (it) 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
US6433196B1 (en) * 2000-02-17 2002-08-13 Sumika Fine Chemicals Co., Ltd. Production method of citalopram, intermediate therefor and production method of the intermediate
GB2357762B (en) * 2000-03-13 2002-01-30 Lundbeck & Co As H Crystalline base of citalopram
US6977306B2 (en) * 2000-05-02 2005-12-20 Sumitomo Chemical Company, Limited Citalopram hydrobromide crystal and method for crystallization thereof

Also Published As

Publication number Publication date
TR200202185T2 (tr) 2002-12-23
HU0100531D0 (en) 2001-03-28
FI20010225A0 (fi) 2001-02-07
ES2173054T1 (es) 2002-10-16
PT1169314E (pt) 2002-11-29
CA2360287C (en) 2003-09-09
DE20007303U1 (de) 2000-07-27
IS5841A (is) 2001-09-14
ITMI20002425A1 (it) 2002-05-09
ITMI20010406A1 (it) 2002-08-28
EP1169314A1 (de) 2002-01-09
FI20010225A (fi) 2001-09-14
CA2411732A1 (en) 2001-09-20
CH691537A5 (de) 2001-08-15
AU746664B2 (en) 2002-05-02
US20030078442A1 (en) 2003-04-24
FR2806086B1 (fr) 2003-05-09
DE60100022D1 (de) 2002-10-10
ATE223396T1 (de) 2002-09-15
CN1680350A (zh) 2005-10-12
UA74360C2 (uk) 2005-12-15
US20050165092A1 (en) 2005-07-28
SK285528B6 (sk) 2007-03-01
HU0100450D0 (en) 2001-04-28
SE0103046L (sv) 2001-11-14
DE10108042A1 (de) 2001-10-18
HUP0100531A2 (hu) 2002-01-28
SI1169314T1 (en) 2002-12-31
CH691477A5 (de) 2001-07-31
JP2003527383A (ja) 2003-09-16
HRP20020756A2 (en) 2004-12-31
FI20010156A0 (fi) 2001-01-25
AT4364U1 (de) 2001-06-25
AR029811A1 (es) 2003-07-16
GB0105982D0 (en) 2001-05-02
SE0200730L (sv) 2002-08-29
DE1227088T1 (de) 2003-02-06
IT1319645B1 (it) 2003-10-23
NO312031B1 (no) 2002-03-04
DK173903B1 (da) 2002-02-11
BG107065A (bg) 2003-05-30
NL1017413C1 (nl) 2001-09-13
HK1054750A1 (en) 2003-12-12
DE60100022T2 (de) 2003-03-06
EA200200972A1 (ru) 2003-02-27
CN1258530C (zh) 2006-06-07
CN1429220A (zh) 2003-07-09
SE517136C2 (sv) 2002-04-16
KR20020080486A (ko) 2002-10-23
FR2806086A1 (fr) 2001-09-14
PL360158A1 (en) 2004-09-06
IES20010109A2 (en) 2002-02-20
ES2180471T1 (es) 2003-02-16
AU2001100197A4 (en) 2001-09-20
CA2360287A1 (en) 2001-09-20
GB2357762A (en) 2001-07-04
DE60100786D1 (de) 2003-10-23
HUP0100531A3 (en) 2004-04-28
DE10164687B4 (de) 2006-04-27
SE0103046D0 (sv) 2001-09-14
SE0200730D0 (sv) 2002-03-12
SI1169314T2 (sl) 2011-08-31
GR1003796B (el) 2002-02-08
EP1169314B1 (de) 2002-09-04
DK1227088T3 (da) 2003-12-22
EP1227088B1 (de) 2003-09-17
NL1016435C1 (nl) 2000-11-06
US20040132808A1 (en) 2004-07-08
SI1227088T1 (en) 2003-12-31
YU68802A (sh) 2005-11-28
WO2001068627A1 (en) 2001-09-20
DE60100786T2 (de) 2004-07-15
DE20121240U1 (de) 2002-07-04
SK13132002A3 (sk) 2003-01-09
ES2173054T3 (es) 2002-12-16
NO20010619L (no) 2001-09-14
ZA200207148B (en) 2003-04-23
EP1227088A1 (de) 2002-07-31
HU0001581D0 (en) 2000-06-28
IL147339A (en) 2004-09-27
DK1169314T3 (da) 2002-10-14
AU3725201A (en) 2001-09-13
ES2159491B1 (es) 2002-05-01
NO315851B1 (no) 2003-11-03
NO20020356L (no) 2001-09-14
GB2357762B (en) 2002-01-30
BR0109373A (pt) 2002-12-24
US20010031784A1 (en) 2001-10-18
NO20010619D0 (no) 2001-02-06
CZ292077B6 (cs) 2003-07-16
IL158072A0 (en) 2004-03-28
US20060247451A1 (en) 2006-11-02
GB0102797D0 (en) 2001-03-21
US20050165244A1 (en) 2005-07-28
NO20020356D0 (no) 2002-01-23
EP1169314B2 (de) 2011-06-01
FI109022B (fi) 2002-05-15
DE60100022T3 (de) 2011-11-17
BE1013210A3 (fr) 2001-10-02
CZ2001808A3 (cs) 2002-01-16
PT1227088E (pt) 2003-12-31
SE526022C2 (sv) 2005-06-14
ES2180471T3 (es) 2004-05-01
MXPA02008793A (es) 2003-02-12
AU2001100197B4 (en) 2001-12-06
US20040167210A1 (en) 2004-08-26
ES2159491A1 (es) 2001-10-01
IL147339A0 (en) 2002-08-14

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