FI20010225A - Kiteinen citalopramin emäs - Google Patents

Kiteinen citalopramin emäs Download PDF

Info

Publication number
FI20010225A
FI20010225A FI20010225A FI20010225A FI20010225A FI 20010225 A FI20010225 A FI 20010225A FI 20010225 A FI20010225 A FI 20010225A FI 20010225 A FI20010225 A FI 20010225A FI 20010225 A FI20010225 A FI 20010225A
Authority
FI
Finland
Prior art keywords
citalopram
crystalline base
crystalline
base
Prior art date
Application number
FI20010225A
Other languages
English (en)
Swedish (sv)
Other versions
FI20010225A0 (fi
FI109022B (fi
Inventor
Hans Petersen
Klaus Peter Boegesoe
Per Holm
Original Assignee
Lundbeck & Co As H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8159320&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FI20010225(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H
Publication of FI20010225A0 publication Critical patent/FI20010225A0/fi
Publication of FI20010225A publication Critical patent/FI20010225A/fi
Application granted granted Critical
Publication of FI109022B publication Critical patent/FI109022B/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Laminated Bodies (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Silicates, Zeolites, And Molecular Sieves (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Manufacture Of Macromolecular Shaped Articles (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI20010225A 2000-03-13 2001-02-07 Sitalopraamin kiteinen emäs FI109022B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DK200000402 2000-03-13
DKPA200000402 2000-03-13
DK0000183 2000-04-13
DKPCT/DK00/00183 2000-04-13

Publications (3)

Publication Number Publication Date
FI20010225A0 FI20010225A0 (fi) 2001-02-07
FI20010225A true FI20010225A (fi) 2001-09-14
FI109022B FI109022B (fi) 2002-05-15

Family

ID=8159320

Family Applications (2)

Application Number Title Priority Date Filing Date
FI20010156A FI20010156A0 (fi) 2000-03-13 2001-01-25 Kiteinen citalopramin emäs
FI20010225A FI109022B (fi) 2000-03-13 2001-02-07 Sitalopraamin kiteinen emäs

Family Applications Before (1)

Application Number Title Priority Date Filing Date
FI20010156A FI20010156A0 (fi) 2000-03-13 2001-01-25 Kiteinen citalopramin emäs

Country Status (42)

Country Link
US (7) US20010031784A1 (fi)
EP (2) EP1169314B2 (fi)
JP (1) JP2003527383A (fi)
KR (1) KR20020080486A (fi)
CN (2) CN1680350A (fi)
AR (1) AR029811A1 (fi)
AT (3) ATE223396T1 (fi)
AU (2) AU746664B2 (fi)
BE (1) BE1013210A3 (fi)
BG (1) BG107065A (fi)
BR (1) BR0109373A (fi)
CA (2) CA2411732A1 (fi)
CH (2) CH691477A5 (fi)
CZ (1) CZ292077B6 (fi)
DE (7) DE20007303U1 (fi)
DK (3) DK173903B1 (fi)
EA (1) EA200200972A1 (fi)
ES (3) ES2180471T3 (fi)
FI (2) FI20010156A0 (fi)
FR (1) FR2806086B1 (fi)
GB (2) GB2357762B (fi)
GR (1) GR1003796B (fi)
HK (1) HK1054750A1 (fi)
HR (1) HRP20020756A2 (fi)
HU (3) HU0001581D0 (fi)
IE (1) IES20010109A2 (fi)
IL (2) IL147339A (fi)
IS (1) IS5841A (fi)
IT (2) IT1319645B1 (fi)
MX (1) MXPA02008793A (fi)
NL (2) NL1016435C1 (fi)
NO (2) NO312031B1 (fi)
PL (1) PL360158A1 (fi)
PT (2) PT1169314E (fi)
SE (2) SE517136C2 (fi)
SI (2) SI1169314T2 (fi)
SK (1) SK285528B6 (fi)
TR (1) TR200202185T2 (fi)
UA (1) UA74360C2 (fi)
WO (1) WO2001068627A1 (fi)
YU (1) YU68802A (fi)
ZA (1) ZA200207148B (fi)

Families Citing this family (61)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU227473B1 (en) 1999-04-14 2011-07-28 Lundbeck & Co As H Method for preparation of citalopram
AR021155A1 (es) * 1999-07-08 2002-06-12 Lundbeck & Co As H Tratamiento de desordenes neuroticos
US7708749B2 (en) 2000-12-20 2010-05-04 Fox Hollow Technologies, Inc. Debulking catheters and methods
US7713279B2 (en) 2000-12-20 2010-05-11 Fox Hollow Technologies, Inc. Method and devices for cutting tissue
US8328829B2 (en) 1999-08-19 2012-12-11 Covidien Lp High capacity debulking catheter with razor edge cutting window
US6299622B1 (en) 1999-08-19 2001-10-09 Fox Hollow Technologies, Inc. Atherectomy catheter with aligned imager
US7887556B2 (en) 2000-12-20 2011-02-15 Fox Hollow Technologies, Inc. Debulking catheters and methods
NL1017417C1 (nl) 2000-03-03 2001-03-16 Lundbeck & Co As H Werkwijze voor de bereiding van Citalopram.
IES20010206A2 (en) 2000-03-13 2002-03-06 Lundbeck & Co As H Method for the preparation of citalopram
GB2357762B (en) * 2000-03-13 2002-01-30 Lundbeck & Co As H Crystalline base of citalopram
US6977306B2 (en) 2000-05-02 2005-12-20 Sumitomo Chemical Company, Limited Citalopram hydrobromide crystal and method for crystallization thereof
AR032455A1 (es) 2000-05-12 2003-11-12 Lundbeck & Co As H Metodo para la preparacion de citalopram, un intermediario empleado en el metodo, un metodo para la preparacion del intermediario empleado en el metodo y composicion farmaceutica antidepresiva
GB2376233B (en) * 2000-08-10 2003-09-10 Lundbeck & Co As H Crystals of a pharmaceutically acceptable salt of citalopram wherein the median size of the crystals is at least 40 microns
CA2353693C (en) * 2000-08-10 2003-07-22 H. Lundbeck A/S Pharmaceutical composition containing citalopram
EP2353526B1 (en) 2000-12-20 2013-09-04 Covidien LP Catheter for removing atheromatous or thrombotic occlusive material
SI1181713T1 (en) * 2000-12-22 2005-02-28 H. Lundbeck A/S Method for the preparation of pure citalopram
AU2001100195B4 (en) * 2001-01-05 2001-12-20 H Lundbeck As Pharmaceutical composition containing citalopram.
GB0105627D0 (en) * 2001-03-07 2001-04-25 Cipla Ltd Preparation of phthalanes
JP2004527551A (ja) * 2001-05-01 2004-09-09 ハー・ルンドベック・アクチエゼルスカベット エナンチオ純粋なエスシタロプラムの使用方法
MEP2108A (xx) 2001-07-31 2010-02-10 Lundbeck & Co As H Kristalni sastav koji sadrži escitalopram
AU2003222435A1 (en) * 2002-01-07 2003-07-24 Sun Pharmaceutical Industries Limited Process for the preparation of 1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)- 1,3-dihydro-5-isobenzofuran carbonitrile
GB2387844B (en) * 2002-02-27 2005-05-11 Matrix Lab Ltd Separation of impurities from a crude mixture of citalopram
GB0204607D0 (en) * 2002-02-27 2002-04-10 Matrix Lab Ltd Process
GB2386118A (en) * 2002-02-27 2003-09-10 Cipla Ltd Citalopram
GB2386119A (en) * 2002-02-27 2003-09-10 Cipla Ltd Purification of citalopram
GB2385848A (en) * 2002-02-27 2003-09-03 Cipla Ltd Citalopram salts
EP1346989A1 (en) * 2002-03-21 2003-09-24 Jubilant Organosys Limited Improved process for the preparation of citalopram and its hydrobromide
GB0206708D0 (en) * 2002-03-21 2002-05-01 Cipla Ltd Pharmaceutical salts
US6812355B2 (en) 2002-10-22 2004-11-02 Sekhsaria Chemicals Limited Process for the manufacture of citalopram hydrobromide from 5-bromophthalide
WO2004085416A1 (en) * 2003-03-24 2004-10-07 Hetero Drugs Limited Novel crystalline forms of (s)-citalopram oxalate
AU2003238676A1 (en) * 2003-04-21 2004-11-19 Podile Khadgapathi An improved process for the preparation of citalopram hydrobromide
US8246640B2 (en) 2003-04-22 2012-08-21 Tyco Healthcare Group Lp Methods and devices for cutting tissue at a vascular location
US7019153B2 (en) 2003-06-10 2006-03-28 Sun Pharmaceutical Industries Limited Process for hydrogenolysis of [1-(3-dimethylamino)propyl)]-1-(4-fluorophenyl)-1,3-dihydro-5-halo-isobenzofuran acetamido-3-substituted-3-cephem-4-carboxylic acid
GB0317475D0 (en) * 2003-07-25 2003-08-27 Meditab Specialities Pvt Ltd Product
JP4025735B2 (ja) * 2003-08-21 2007-12-26 ローム アンド ハース カンパニー 水性系を処理する方法
GB0320312D0 (en) 2003-08-29 2003-10-01 Novartis Ag Purification process
CN100569765C (zh) * 2003-12-19 2009-12-16 杭州民生药业集团有限公司 西酞普兰中间体晶体碱
ITTO20050301A1 (it) * 2005-05-05 2006-11-06 Errekappa Euroterapici Spa Formulazioni liquide orali contenenti citalopram
EP1901714A2 (en) * 2005-05-20 2008-03-26 Aurobindo Pharma Limited Pharmaceutical dosage forms comprising escitalopram in form of granules
US7834201B2 (en) 2005-06-22 2010-11-16 H. Lundbeck A/S Crystalline base of escitalopram and orodispersible tablets comprising escitalopram base
TWI347942B (en) * 2005-06-22 2011-09-01 Lundbeck & Co As H Crystalline base of escitalopram and orodispersible tablets comprising escitalopram base
NZ561375A (en) * 2005-06-27 2011-06-30 Biovail Lab Int Srl Bupropion hydrobromide, and crystalline forms, compositions, and uses of this compound
US20070276419A1 (en) 2006-05-26 2007-11-29 Fox Hollow Technologies, Inc. Methods and devices for rotating an active element and an energy emitter on a catheter
US8784440B2 (en) 2008-02-25 2014-07-22 Covidien Lp Methods and devices for cutting tissue
EP3275383A1 (en) 2008-10-13 2018-01-31 Covidien LP Devices and methods for manipulating a catheter shaft
JP5579830B2 (ja) 2009-04-29 2014-08-27 コヴィディエン リミテッド パートナーシップ 組織を切断および研磨する方法および装置
US8192452B2 (en) 2009-05-14 2012-06-05 Tyco Healthcare Group Lp Easily cleaned atherectomy catheters and methods of use
CA2781046C (en) 2009-12-02 2014-09-16 Tyco Healthcare Group Lp Methods and devices for cutting tissue
AU2010328078B2 (en) 2009-12-11 2013-07-04 Covidien Lp Material removal device having improved material capture efficiency and methods of use
EP2742881B1 (en) 2010-06-14 2015-10-07 Covidien LP Material removal device
BR112013009835A2 (pt) 2010-10-28 2016-07-26 Covidien Lp dispositivo para a remoção de material e método de uso
EP2659840B1 (en) 2010-11-11 2017-02-01 Covidien LP Flexible debulking catheters with imaging
US8992717B2 (en) 2011-09-01 2015-03-31 Covidien Lp Catheter with helical drive shaft and methods of manufacture
US9579157B2 (en) 2012-09-13 2017-02-28 Covidien Lp Cleaning device for medical instrument and method of use
US9943329B2 (en) 2012-11-08 2018-04-17 Covidien Lp Tissue-removing catheter with rotatable cutter
WO2015200702A1 (en) 2014-06-27 2015-12-30 Covidien Lp Cleaning device for catheter and catheter including the same
US10314667B2 (en) 2015-03-25 2019-06-11 Covidien Lp Cleaning device for cleaning medical instrument
US10292721B2 (en) 2015-07-20 2019-05-21 Covidien Lp Tissue-removing catheter including movable distal tip
US10314664B2 (en) 2015-10-07 2019-06-11 Covidien Lp Tissue-removing catheter and tissue-removing element with depth stop
CA3145388A1 (en) 2019-07-19 2021-01-28 Bioxcel Therapeutics, Inc. Non-sedating dexmedetomidine treatment regimens
US11806334B1 (en) 2023-01-12 2023-11-07 Bioxcel Therapeutics, Inc. Non-sedating dexmedetomidine treatment regimens

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US2233970A (en) * 1941-03-04 Quinoline compound and process of
US2584429A (en) * 1950-12-29 1952-02-05 Rohm & Haas 1,1-diphenyl-4-tert.-amino-2-butyne-1-ols
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GB8419963D0 (en) * 1984-08-06 1984-09-12 Lundbeck & Co As H Intermediate compound and method
GB8814057D0 (en) * 1988-06-14 1988-07-20 Lundbeck & Co As H New enantiomers & their isolation
DK213290D0 (da) 1990-09-06 1990-09-06 Lundbeck & Co As H Treatment of cerebrovascular disorders
US5296507A (en) * 1990-09-06 1994-03-22 H.Lundbeck A/S Treatment of cerbrovascular disorders
CA2120874E (en) * 1994-04-08 2002-01-08 Keshava Murthy Form of form 1 ranitidine
JP3526581B2 (ja) * 1997-07-08 2004-05-17 ハー・ルンドベック・アクティーゼルスカブ シタロプラムの製造方法
UA62985C2 (en) * 1997-11-10 2004-01-15 Lunnbeck As H A method for the preparation of citalopram
CA2291072C (en) * 1997-11-11 2002-08-20 H. Lundbeck A/S Method for the preparation of citalopram
DK1123284T3 (da) * 1998-10-20 2003-04-28 Lundbeck & Co As H Fremgangsmåde til fremstilling af citalopram
HU227473B1 (en) 1999-04-14 2011-07-28 Lundbeck & Co As H Method for preparation of citalopram
ITMI991581A1 (it) 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
ITMI991579A1 (it) 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
US6433196B1 (en) * 2000-02-17 2002-08-13 Sumika Fine Chemicals Co., Ltd. Production method of citalopram, intermediate therefor and production method of the intermediate
GB2357762B (en) * 2000-03-13 2002-01-30 Lundbeck & Co As H Crystalline base of citalopram
US6977306B2 (en) * 2000-05-02 2005-12-20 Sumitomo Chemical Company, Limited Citalopram hydrobromide crystal and method for crystallization thereof

Also Published As

Publication number Publication date
SE0200730L (sv) 2002-08-29
DK1169314T3 (da) 2002-10-14
EP1169314B1 (en) 2002-09-04
DE10164687B4 (de) 2006-04-27
ATE223396T1 (de) 2002-09-15
SE0103046D0 (sv) 2001-09-14
HK1054750A1 (en) 2003-12-12
FR2806086A1 (fr) 2001-09-14
GB2357762A (en) 2001-07-04
SI1169314T1 (en) 2002-12-31
GR1003796B (el) 2002-02-08
CN1429220A (zh) 2003-07-09
FI20010225A0 (fi) 2001-02-07
DE10108042A1 (de) 2001-10-18
CZ292077B6 (cs) 2003-07-16
AR029811A1 (es) 2003-07-16
ES2159491B1 (es) 2002-05-01
IL147339A0 (en) 2002-08-14
DE1227088T1 (de) 2003-02-06
CH691477A5 (de) 2001-07-31
AT4364U1 (de) 2001-06-25
ES2180471T3 (es) 2004-05-01
PT1227088E (pt) 2003-12-31
DE60100022T3 (de) 2011-11-17
BR0109373A (pt) 2002-12-24
AU3725201A (en) 2001-09-13
SE0103046L (sv) 2001-11-14
NO20020356L (no) 2001-09-14
IES20010109A2 (en) 2002-02-20
YU68802A (sh) 2005-11-28
TR200202185T2 (tr) 2002-12-23
DE60100022T2 (de) 2003-03-06
HU0100531D0 (en) 2001-03-28
AU2001100197B4 (en) 2001-12-06
IL147339A (en) 2004-09-27
US20060247451A1 (en) 2006-11-02
ES2173054T3 (es) 2002-12-16
ES2180471T1 (es) 2003-02-16
CA2411732A1 (en) 2001-09-20
SK285528B6 (sk) 2007-03-01
PL360158A1 (en) 2004-09-06
PT1169314E (pt) 2002-11-29
SE0200730D0 (sv) 2002-03-12
SE517136C2 (sv) 2002-04-16
HUP0100531A2 (hu) 2002-01-28
EA200200972A1 (ru) 2003-02-27
DE60100786T2 (de) 2004-07-15
US20030078442A1 (en) 2003-04-24
NO20010619L (no) 2001-09-14
BE1013210A3 (fr) 2001-10-02
CZ2001808A3 (cs) 2002-01-16
CA2360287C (en) 2003-09-09
DE20007303U1 (de) 2000-07-27
GB2357762B (en) 2002-01-30
IS5841A (is) 2001-09-14
EP1169314A1 (en) 2002-01-09
SK13132002A3 (sk) 2003-01-09
ES2173054T1 (es) 2002-10-16
CH691537A5 (de) 2001-08-15
CA2360287A1 (en) 2001-09-20
US20040167210A1 (en) 2004-08-26
BG107065A (bg) 2003-05-30
EP1227088B1 (en) 2003-09-17
DE20121240U1 (de) 2002-07-04
FR2806086B1 (fr) 2003-05-09
EP1169314B2 (en) 2011-06-01
GB0105982D0 (en) 2001-05-02
NL1016435C1 (nl) 2000-11-06
DE60100786D1 (de) 2003-10-23
SI1227088T1 (en) 2003-12-31
NO20010619D0 (no) 2001-02-06
ES2159491A1 (es) 2001-10-01
NO312031B1 (no) 2002-03-04
DK1227088T3 (da) 2003-12-22
JP2003527383A (ja) 2003-09-16
EP1227088A1 (en) 2002-07-31
NO315851B1 (no) 2003-11-03
WO2001068627A1 (en) 2001-09-20
UA74360C2 (uk) 2005-12-15
US20050165092A1 (en) 2005-07-28
SE526022C2 (sv) 2005-06-14
ITMI20010406A1 (it) 2002-08-28
US20010031784A1 (en) 2001-10-18
ZA200207148B (en) 2003-04-23
SI1169314T2 (sl) 2011-08-31
CN1258530C (zh) 2006-06-07
IT1319645B1 (it) 2003-10-23
HU0100450D0 (en) 2001-04-28
HRP20020756A2 (en) 2004-12-31
AU746664B2 (en) 2002-05-02
CN1680350A (zh) 2005-10-12
ATE250050T1 (de) 2003-10-15
US20040132808A1 (en) 2004-07-08
FI20010156A0 (fi) 2001-01-25
HUP0100531A3 (en) 2004-04-28
NL1017413C1 (nl) 2001-09-13
ITMI20002425A1 (it) 2002-05-09
GB0102797D0 (en) 2001-03-21
IL158072A0 (en) 2004-03-28
FI109022B (fi) 2002-05-15
DE60100022D1 (de) 2002-10-10
KR20020080486A (ko) 2002-10-23
HU0001581D0 (en) 2000-06-28
NO20020356D0 (no) 2002-01-23
US20050165244A1 (en) 2005-07-28
AU2001100197A4 (en) 2001-09-20
DK173903B1 (da) 2002-02-11
MXPA02008793A (es) 2003-02-12

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