UA126373C2 - Композиція і спосіб для імуноонкології - Google Patents

Композиція і спосіб для імуноонкології Download PDF

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Publication number
UA126373C2
UA126373C2 UAA201807453A UAA201807453A UA126373C2 UA 126373 C2 UA126373 C2 UA 126373C2 UA A201807453 A UAA201807453 A UA A201807453A UA A201807453 A UAA201807453 A UA A201807453A UA 126373 C2 UA126373 C2 UA 126373C2
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Ukraine
Prior art keywords
molecule
nrna
cell
reading
zeo
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UAA201807453A
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English (en)
Ukrainian (uk)
Inventor
Мін-Вей Чень
Мин-Вэй Чень
Мелісса Дек
Мелисса Дек
Гленн Дранофф
Крейг Мікенін
Крейг Микенин
Рейнальд Лескарбо
Селеста Річардсон
Селеста РИЧАРДСОН
Морег Стюарт
І Ян
И Ян
Original Assignee
Новартіс Аг
Новартис Аг
Інтелліа Терапьютікс, Інк.
Интеллиа Терапьютикс, Инк.
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Application filed by Новартіс Аг, Новартис Аг, Інтелліа Терапьютікс, Інк., Интеллиа Терапьютикс, Инк. filed Critical Новартіс Аг
Publication of UA126373C2 publication Critical patent/UA126373C2/uk

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    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
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    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
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    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
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    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
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    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
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    • C12N15/1135—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against oncogenes or tumor suppressor genes
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    • C12N15/1138—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against receptors or cell surface proteins
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    • C12N15/90—Stable introduction of foreign DNA into chromosome
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    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
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UAA201807453A 2015-12-04 2016-12-02 Композиція і спосіб для імуноонкології UA126373C2 (uk)

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Application Number Priority Date Filing Date Title
US201562263169P 2015-12-04 2015-12-04
US201662316784P 2016-04-01 2016-04-01
US201662394290P 2016-09-14 2016-09-14
PCT/IB2016/057318 WO2017093969A1 (en) 2015-12-04 2016-12-02 Compositions and methods for immunooncology

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UA126373C2 true UA126373C2 (uk) 2022-09-28

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