RU2107097C1 - Способ получения лизина - Google Patents

Способ получения лизина Download PDF

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Publication number
RU2107097C1
RU2107097C1 SU5052640A SU5052640A RU2107097C1 RU 2107097 C1 RU2107097 C1 RU 2107097C1 SU 5052640 A SU5052640 A SU 5052640A SU 5052640 A SU5052640 A SU 5052640A RU 2107097 C1 RU2107097 C1 RU 2107097C1
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RU
Russia
Prior art keywords
lysine
leucine
concentration
medium
fermentation
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SU5052640A
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English (en)
Russian (ru)
Inventor
Пфефферле Вальтер
Лоттер Херманн
Фридрих Хайнц
Дегенер Вольфганг
Original Assignee
Дегусса Аг
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Publication of RU2107097C1 publication Critical patent/RU2107097C1/ru

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
SU5052640A 1991-09-17 1992-09-16 Способ получения лизина RU2107097C1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DEP4130867.0 1991-09-17
DE4130867A DE4130867A1 (de) 1991-09-17 1991-09-17 Verfahren zur fermentativen herstellung von aminosaeuren

Publications (1)

Publication Number Publication Date
RU2107097C1 true RU2107097C1 (ru) 1998-03-20

Family

ID=6440783

Family Applications (1)

Application Number Title Priority Date Filing Date
SU5052640A RU2107097C1 (ru) 1991-09-17 1992-09-16 Способ получения лизина

Country Status (20)

Country Link
US (1) US5770409A (https=)
EP (1) EP0532867B1 (https=)
JP (1) JP2965799B2 (https=)
KR (1) KR100254023B1 (https=)
CN (1) CN1038693C (https=)
AT (1) ATE149571T1 (https=)
AU (1) AU656416B2 (https=)
BR (1) BR9203587A (https=)
CA (1) CA2078364C (https=)
CZ (1) CZ263392A3 (https=)
DE (2) DE4130867A1 (https=)
DK (1) DK0532867T3 (https=)
ES (1) ES2098398T3 (https=)
FI (1) FI104836B (https=)
GR (1) GR3023364T3 (https=)
MX (1) MX9205248A (https=)
RU (1) RU2107097C1 (https=)
SK (1) SK279888B6 (https=)
TW (1) TW206984B (https=)
UA (1) UA27034C2 (https=)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2187942C2 (ru) * 1998-06-17 2002-08-27 Арчер Дэниелс Мидленд Компани Способ получения гранулированной кормовой добавки l-лизина (варианты)
RU2350655C2 (ru) * 2004-10-07 2009-03-27 Адзиномото Ко., Инк. Способ получения основного вещества
RU2486248C2 (ru) * 2011-06-29 2013-06-27 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Московский государственный университет инженерной экологии" (ФГБОУ ВПО "МГУИЭ") Способ биосинтеза l-лизина

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DE19547361A1 (de) * 1995-12-19 1997-06-26 Degussa Verfahren zur Herstellung von L-Aminosäuren durch Fermentation
CA2255130A1 (en) 1997-12-16 1999-06-16 Archer Daniels Midland Company Process for making granular l-lysine feed supplement
CN1236690C (zh) * 1999-06-23 2006-01-18 德古萨股份公司 含有赖氨酸的含水动物饲料添加剂及其生产方法
DE10021828A1 (de) * 2000-05-04 2001-11-08 Degussa Neue für das cdsA-Gen kodierende Nukleotidsequenzen
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JP4362959B2 (ja) * 2000-08-24 2009-11-11 味の素株式会社 塩基性アミノ酸の製造方法
JP2002284749A (ja) 2001-03-23 2002-10-03 Ajinomoto Co Inc 塩基性アミノ酸溶液の製造方法
US7718361B2 (en) 2002-12-06 2010-05-18 Roche Molecular Systems, Inc. Quantitative test for bacterial pathogens
US20040115304A1 (en) * 2002-12-16 2004-06-17 Frank Dubner Feesdstuffs additives containing L-lysine with improved abrasion resistance, and process for their production
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DE102004026152A1 (de) * 2004-05-28 2005-12-15 Basf Ag Fermentative Herstellung von Feinchemikalien
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US20070082031A1 (en) 2005-10-08 2007-04-12 Hermann Lotter L-lysine-containing feed additives
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DE102006032634A1 (de) 2006-07-13 2008-01-17 Evonik Degussa Gmbh Verfahren zur Herstellung von L-Aminosäuren
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DE102009030342A1 (de) 2009-06-25 2010-12-30 Evonik Degussa Gmbh Verfahren zur fermentativen Herstellung von organisch chemischen Verbindungen
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PL2700715T3 (pl) 2012-08-20 2019-03-29 Evonik Degussa Gmbh Sposób fermentacyjnego wytwarzania L-aminokwasów z zastosowaniem ulepszonych szczepów z rodziny Enterobacteriaceae
DE102012024435A1 (de) 2012-12-14 2014-07-10 Forschungszentrum Jülich GmbH Verfahren zur Identifizierung einer Zelle mit gegenüber ihrem Wildtyp erhöhten intrazellulären Konzentration eines bestimmten Metaboliten, wobei die Veränderung der Zelle durch Rekombi-neering erreicht wird, sowie ein Verfahren zur Herstellung einer gegenüber ihrem Wildtyp genetisch veränderten Produktionszelle mit optimierter Produktion eines bestimmten Metaboliten, ein Verfahren zur Herstellung dieses Metaboliten, sowie dafür geeignete Nukleinsäuren
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US11208649B2 (en) 2015-12-07 2021-12-28 Zymergen Inc. HTP genomic engineering platform
US9988624B2 (en) 2015-12-07 2018-06-05 Zymergen Inc. Microbial strain improvement by a HTP genomic engineering platform
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JP2019062742A (ja) 2016-02-24 2019-04-25 味の素株式会社 Ｌ−アミノ酸の製造法
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CN108018325B (zh) * 2017-08-23 2020-10-09 江南大学 提高谷胱甘肽产量的方法
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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU1157059A1 (ru) * 1983-02-28 1985-05-23 Белорусский Ордена Трудового Красного Знамени Технологический Институт Им.С.М.Кирова Способ получени @ -лизина
DD269167A1 (de) * 1987-07-30 1989-06-21 Ve Forschungszentrum Biotechno Verfahren zur mikrobiologischen herstellung von l-lysin

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE269167C (https=) *
FR2488273A1 (fr) * 1980-08-07 1982-02-12 Inst Mikrobiologii Im Avg Procede microbiologique de preparation de l-lysine et l-lysine obtenue par ledit procede
JPS57115186A (en) * 1980-12-29 1982-07-17 Ajinomoto Co Inc Preparation of l-lysine by fermentation
DD268834A3 (de) * 1983-06-03 1989-06-14 Ve Forschungszentrum Biotechno Verfahren zur fermentativen herstellung von l-lysin
FR2604447B1 (fr) * 1986-09-29 1989-05-19 Ajinomoto Kk Procede de production de l-threonine par fermentation
KR910002850B1 (ko) * 1989-03-30 1991-05-06 제일제당 주식회사 L-라이신을 생산하는 미생물 및 이를 이용한 l-라이신의 제조방법
AU5600590A (en) * 1989-06-01 1990-12-06 Unisearch Limited High lysine producing microorganisms

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU1157059A1 (ru) * 1983-02-28 1985-05-23 Белорусский Ордена Трудового Красного Знамени Технологический Институт Им.С.М.Кирова Способ получени @ -лизина
DD269167A1 (de) * 1987-07-30 1989-06-21 Ve Forschungszentrum Biotechno Verfahren zur mikrobiologischen herstellung von l-lysin

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Biotechn. Lettors, 10, N 8, 1988, 583 - 586. *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2187942C2 (ru) * 1998-06-17 2002-08-27 Арчер Дэниелс Мидленд Компани Способ получения гранулированной кормовой добавки l-лизина (варианты)
RU2350655C2 (ru) * 2004-10-07 2009-03-27 Адзиномото Ко., Инк. Способ получения основного вещества
RU2486248C2 (ru) * 2011-06-29 2013-06-27 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Московский государственный университет инженерной экологии" (ФГБОУ ВПО "МГУИЭ") Способ биосинтеза l-лизина

Also Published As

Publication number Publication date
GR3023364T3 (en) 1997-08-29
KR930006157A (ko) 1993-04-20
UA27034C2 (uk) 2000-02-28
AU2455992A (en) 1993-03-18
CA2078364A1 (en) 1993-03-18
DE59208102D1 (de) 1997-04-10
FI924146A0 (fi) 1992-09-16
EP0532867B1 (de) 1997-03-05
TW206984B (https=) 1993-06-01
DK0532867T3 (da) 1997-07-28
KR100254023B1 (ko) 2000-04-15
EP0532867A1 (de) 1993-03-24
JPH05244969A (ja) 1993-09-24
US5770409A (en) 1998-06-23
SK263392A3 (en) 1996-01-10
ATE149571T1 (de) 1997-03-15
FI924146L (fi) 1993-03-18
CN1038693C (zh) 1998-06-10
MX9205248A (es) 1993-05-01
CA2078364C (en) 2003-05-06
CN1070687A (zh) 1993-04-07
BR9203587A (pt) 1993-04-13
ES2098398T3 (es) 1997-05-01
CZ263392A3 (en) 1993-04-14
AU656416B2 (en) 1995-02-02
SK279888B6 (sk) 1999-05-07
DE4130867A1 (de) 1993-03-18
JP2965799B2 (ja) 1999-10-18
FI104836B (fi) 2000-04-14

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