RU2016111360A - Пептидомиметические макроциклы - Google Patents

Пептидомиметические макроциклы Download PDF

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Publication number
RU2016111360A
RU2016111360A RU2016111360A RU2016111360A RU2016111360A RU 2016111360 A RU2016111360 A RU 2016111360A RU 2016111360 A RU2016111360 A RU 2016111360A RU 2016111360 A RU2016111360 A RU 2016111360A RU 2016111360 A RU2016111360 A RU 2016111360A
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Russia
Prior art keywords
peptidomimetic macrocycles
amino acid
acid sequence
peptidomimetic
macrocycles
Prior art date
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RU2016111360A
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English (en)
Russian (ru)
Inventor
Венсан ГЕРЛАВЭ
Нориюки КАВАХАТА
Original Assignee
Эйлерон Терапьютикс, Инк.
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Publication of RU2016111360A publication Critical patent/RU2016111360A/ru

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50Cyclic peptides containing at least one abnormal peptide link
    • C07K7/52Cyclic peptides containing at least one abnormal peptide link with only normal peptide links in the ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4746Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used p53
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64Cyclic peptides containing only normal peptide links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
RU2016111360A 2010-08-13 2011-08-13 Пептидомиметические макроциклы RU2016111360A (ru)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US37363810P 2010-08-13 2010-08-13
US37370110P 2010-08-13 2010-08-13
US61/373,638 2010-08-13
US61/373,701 2010-08-13
US37416310P 2010-08-16 2010-08-16
US61/374,163 2010-08-16

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
RU2013110845/04A Division RU2582678C2 (ru) 2010-08-13 2011-08-13 Пептидомиметические макроциклы

Publications (1)

Publication Number Publication Date
RU2016111360A true RU2016111360A (ru) 2018-11-27

Family

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Family Applications (2)

Application Number Title Priority Date Filing Date
RU2016111360A RU2016111360A (ru) 2010-08-13 2011-08-13 Пептидомиметические макроциклы
RU2013110845/04A RU2582678C2 (ru) 2010-08-13 2011-08-13 Пептидомиметические макроциклы

Family Applications After (1)

Application Number Title Priority Date Filing Date
RU2013110845/04A RU2582678C2 (ru) 2010-08-13 2011-08-13 Пептидомиметические макроциклы

Country Status (15)

Country Link
US (5) US8859723B2 (enExample)
EP (1) EP2603600B1 (enExample)
JP (3) JP2013535514A (enExample)
KR (4) KR20180058866A (enExample)
CN (2) CN103282510A (enExample)
BR (1) BR112013003248A2 (enExample)
CA (1) CA2807685C (enExample)
DK (1) DK2603600T3 (enExample)
ES (1) ES2711526T3 (enExample)
MX (2) MX355543B (enExample)
PL (1) PL2603600T3 (enExample)
PT (1) PT2603600T (enExample)
RU (2) RU2016111360A (enExample)
SI (1) SI2603600T1 (enExample)
WO (3) WO2012021875A1 (enExample)

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