PL3612234T3 - Terapia skojarzona z koniugatem anty-AXL przeciwciało-lek - Google Patents

Terapia skojarzona z koniugatem anty-AXL przeciwciało-lek

Info

Publication number
PL3612234T3
PL3612234T3 PL18719162.2T PL18719162T PL3612234T3 PL 3612234 T3 PL3612234 T3 PL 3612234T3 PL 18719162 T PL18719162 T PL 18719162T PL 3612234 T3 PL3612234 T3 PL 3612234T3
Authority
PL
Poland
Prior art keywords
combination therapy
drug conjugate
axl antibody
axl
antibody
Prior art date
Application number
PL18719162.2T
Other languages
English (en)
Polish (pl)
Inventor
Patricius Hendrikus Cornelis VAN BERKEL
Jens WUERTHNER
John Hartley
Francesca ZAMMARCHI
Original Assignee
Adc Therapeutics Sa
Medimmune Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB1706227.4A external-priority patent/GB201706227D0/en
Priority claimed from GBGB1706225.8A external-priority patent/GB201706225D0/en
Priority claimed from GBGB1706226.6A external-priority patent/GB201706226D0/en
Priority claimed from GBGB1706224.1A external-priority patent/GB201706224D0/en
Priority claimed from GBGB1706229.0A external-priority patent/GB201706229D0/en
Priority claimed from GBGB1706228.2A external-priority patent/GB201706228D0/en
Priority claimed from GBGB1706230.8A external-priority patent/GB201706230D0/en
Priority claimed from GBGB1706231.6A external-priority patent/GB201706231D0/en
Priority claimed from GBGB1706223.3A external-priority patent/GB201706223D0/en
Application filed by Adc Therapeutics Sa, Medimmune Limited filed Critical Adc Therapeutics Sa
Publication of PL3612234T3 publication Critical patent/PL3612234T3/pl

Links

Classifications

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    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
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    • A61K2039/507—Comprising a combination of two or more separate antibodies
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C—CHEMISTRY; METALLURGY
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    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

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