MX381908B - Receptores de antigenos quimericos de cadena sencilla especificos de anti-cll1 para inmunoterapia de cancer. - Google Patents

Receptores de antigenos quimericos de cadena sencilla especificos de anti-cll1 para inmunoterapia de cancer.

Info

Publication number
MX381908B
MX381908B MX2017009181A MX2017009181A MX381908B MX 381908 B MX381908 B MX 381908B MX 2017009181 A MX2017009181 A MX 2017009181A MX 2017009181 A MX2017009181 A MX 2017009181A MX 381908 B MX381908 B MX 381908B
Authority
MX
Mexico
Prior art keywords
cll1
chimeric antigen
antigen receptors
cancer immunotherapy
specific single
Prior art date
Application number
MX2017009181A
Other languages
English (en)
Other versions
MX2017009181A (es
Inventor
Alexandre Juillerat
Arvind Rajpal
Barbra Johnson Sasu
Julianne Smith
Julien Valton
Philippe Duchateau
Original Assignee
Cellectis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cellectis filed Critical Cellectis
Publication of MX2017009181A publication Critical patent/MX2017009181A/es
Publication of MX381908B publication Critical patent/MX381908B/es

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    • A61K35/14—Blood; Artificial blood
    • A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
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    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
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Abstract

La presente invención se refiere a Receptores de Antígenos Quiméricos (CAR) que son proteínas quiméricas recombinantes capaces de redirigir la especificidad y reactividad de las células inmunitarias hacia células CLL1-positivas. Las células inmunitarias genéticamente manipuladas dotadas de dichos CARs son particularmente adecuadas para la inmunoterapia para el tratamiento de cáncer, en particular leucemia.
MX2017009181A 2015-01-26 2016-01-25 Receptores de antigenos quimericos de cadena sencilla especificos de anti-cll1 para inmunoterapia de cancer. MX381908B (es)

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PCT/EP2016/051469 WO2016120218A1 (en) 2015-01-26 2016-01-25 ANTI-CLL1 SPECIFIC SINGLE-CHAIN CHIMERIC ANTIGEN RECEPTORS (scCARS) FOR CANCER IMMUNOTHERAPY

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MX2017009349A MX2017009349A (es) 2015-01-26 2016-01-25 Celulas inmunitarias geneticamente manipuladas para inactivacion de receptor de cleulas t, dotadas con receptores de antigenos quimericos de union a cd123 para el tratamiento de linfoma mieloide agudo o neoplasia de celulas dendriticas plasmacitoides blasticas recidivante/refractaria.
MX2017009182A MX389057B (es) 2015-01-26 2016-01-25 Sistemas de receptor de antigeno quimerico impulsado por mab para clasificar/reducir celulas inmunes diseñadas.
MX2017009181A MX381908B (es) 2015-01-26 2016-01-25 Receptores de antigenos quimericos de cadena sencilla especificos de anti-cll1 para inmunoterapia de cancer.

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MX2017009182A MX389057B (es) 2015-01-26 2016-01-25 Sistemas de receptor de antigeno quimerico impulsado por mab para clasificar/reducir celulas inmunes diseñadas.

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CA2973524A1 (en) 2016-08-04
CA2973525C (en) 2021-12-14
AU2016212160A1 (en) 2017-07-13
RU2732925C2 (ru) 2020-09-24
RU2017129591A3 (es) 2019-08-05
KR20170134331A (ko) 2017-12-06
CA2973532A1 (en) 2016-08-04
BR112017013981A2 (pt) 2018-01-02
KR102661969B1 (ko) 2024-04-29
EP3250606B1 (en) 2020-11-25
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BR112017015453A2 (pt) 2018-01-23
MX2017009349A (es) 2017-09-26
RU2017129592A (ru) 2019-02-28
JP6884709B2 (ja) 2021-06-09
US20180002435A1 (en) 2018-01-04
US20240228636A1 (en) 2024-07-11
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WO2016120219A1 (en) 2016-08-04
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CN107531801A (zh) 2018-01-02
IL253012A0 (en) 2017-08-31
JP2018504459A (ja) 2018-02-15
CN107406516A (zh) 2017-11-28
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ES2842212T3 (es) 2021-07-13
MX2017009182A (es) 2018-04-20
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RU2731543C2 (ru) 2020-09-04
DK3250606T3 (da) 2021-01-04
JP2018504145A (ja) 2018-02-15
EP3250602A1 (en) 2017-12-06
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RU2017129592A3 (es) 2019-07-17
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IL252937B (en) 2021-09-30
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