MX2017009182A - Sistemas de receptor de antigeno quimerico impulsado por mab para clasificar/reducir celulas inmunes diseñadas. - Google Patents
Sistemas de receptor de antigeno quimerico impulsado por mab para clasificar/reducir celulas inmunes diseñadas.Info
- Publication number
- MX2017009182A MX2017009182A MX2017009182A MX2017009182A MX2017009182A MX 2017009182 A MX2017009182 A MX 2017009182A MX 2017009182 A MX2017009182 A MX 2017009182A MX 2017009182 A MX2017009182 A MX 2017009182A MX 2017009182 A MX2017009182 A MX 2017009182A
- Authority
- MX
- Mexico
- Prior art keywords
- mab
- sorting
- antigen receptor
- chimeric antigen
- immune cells
- Prior art date
Links
- 108010019670 Chimeric Antigen Receptors Proteins 0.000 title abstract 3
- 230000000779 depleting effect Effects 0.000 title 1
- 210000002865 immune cell Anatomy 0.000 title 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
Classifications
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- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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Abstract
Un polipéptido que codifica un receptor de antígeno quimérico (CAR) que comprende al menos un dominio de unión extracelular que comprende un scFv formado por al menos una cadena de VH y una cadena de VL específicas a un antígeno, en donde el dominio de unión extracelular comprende al menos un epítopo específico de mAb.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DKPA201570044 | 2015-01-26 | ||
PCT/EP2016/051467 WO2016120216A1 (en) | 2015-01-26 | 2016-01-25 | mAb-DRIVEN CHIMERIC ANTIGEN RECEPTOR SYSTEMS FOR SORTING/DEPLETING ENGINEERED IMMUNE CELLS |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2017009182A true MX2017009182A (es) | 2018-04-20 |
Family
ID=52396337
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2017009349A MX2017009349A (es) | 2015-01-26 | 2016-01-25 | Celulas inmunitarias geneticamente manipuladas para inactivacion de receptor de cleulas t, dotadas con receptores de antigenos quimericos de union a cd123 para el tratamiento de linfoma mieloide agudo o neoplasia de celulas dendriticas plasmacitoides blasticas recidivante/refractaria. |
MX2017009182A MX2017009182A (es) | 2015-01-26 | 2016-01-25 | Sistemas de receptor de antigeno quimerico impulsado por mab para clasificar/reducir celulas inmunes diseñadas. |
MX2017009181A MX2017009181A (es) | 2015-01-26 | 2016-01-25 | Receptores de antigenos quimericos de cadena sencilla especificos de anti-cll1 para inmunoterapia de cancer. |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2017009349A MX2017009349A (es) | 2015-01-26 | 2016-01-25 | Celulas inmunitarias geneticamente manipuladas para inactivacion de receptor de cleulas t, dotadas con receptores de antigenos quimericos de union a cd123 para el tratamiento de linfoma mieloide agudo o neoplasia de celulas dendriticas plasmacitoides blasticas recidivante/refractaria. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2017009181A MX2017009181A (es) | 2015-01-26 | 2016-01-25 | Receptores de antigenos quimericos de cadena sencilla especificos de anti-cll1 para inmunoterapia de cancer. |
Country Status (14)
Country | Link |
---|---|
US (5) | US20180002435A1 (es) |
EP (5) | EP3250602A1 (es) |
JP (5) | JP2018504143A (es) |
KR (2) | KR102329836B1 (es) |
CN (5) | CN113968915A (es) |
AU (5) | AU2016212160B2 (es) |
BR (3) | BR112017014547A2 (es) |
CA (5) | CA2973529A1 (es) |
DK (2) | DK3250606T3 (es) |
ES (2) | ES2842212T3 (es) |
IL (3) | IL252937B (es) |
MX (3) | MX2017009349A (es) |
RU (3) | RU2732925C2 (es) |
WO (5) | WO2016120219A1 (es) |
Families Citing this family (136)
Publication number | Priority date | Publication date | Assignee | Title |
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US9950282B2 (en) | 2012-03-15 | 2018-04-24 | Flodesign Sonics, Inc. | Electronic configuration and control for acoustic standing wave generation |
US10967298B2 (en) | 2012-03-15 | 2021-04-06 | Flodesign Sonics, Inc. | Driver and control for variable impedence load |
US9458450B2 (en) | 2012-03-15 | 2016-10-04 | Flodesign Sonics, Inc. | Acoustophoretic separation technology using multi-dimensional standing waves |
US10704021B2 (en) | 2012-03-15 | 2020-07-07 | Flodesign Sonics, Inc. | Acoustic perfusion devices |
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