ME00145B - Upotreba supstituisanih jedinjenja azetidinona za lečenje sitosterolemije - Google Patents

Upotreba supstituisanih jedinjenja azetidinona za lečenje sitosterolemije

Info

Publication number
ME00145B
ME00145B MEP-2008-268A MEP26808A ME00145B ME 00145 B ME00145 B ME 00145B ME P26808 A MEP26808 A ME P26808A ME 00145 B ME00145 B ME 00145B
Authority
ME
Montenegro
Prior art keywords
sitosterolemia
treatment
substituted azetidinone
azetidinone compounds
compounds
Prior art date
Application number
MEP-2008-268A
Other languages
English (en)
Inventor
Harry R Davis
Original Assignee
Merck Sharp & Dohme
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23006987&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ME00145(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merck Sharp & Dohme filed Critical Merck Sharp & Dohme
Publication of MEP26808A publication Critical patent/MEP26808A/xx
Publication of ME00145B publication Critical patent/ME00145B/me

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Molecular Biology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pulmonology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Predstavljeni pronalazak je namenjen upotrebi jedinjenja koja inhibiraju resorpciju stanola, njihove farmaceutske oblike, terapijske kombinacije i njihovu upotrebu u kombinaciji sa drugim agensima za smanjenje lipida kod lečenja i prevenciju sitosterolemije ili/i za smanjenje koncentracije sterola, kao i holesterola u plazmi i tkivu sisara. Metodi lečenja ili prevencije vaskulamih bolesti i koronarnih događaja su takođe ponuđeni.
MEP-2008-268A 2001-01-26 2002-01-25 Upotreba supstituisanih jedinjenja azetidinona za lečenje sitosterolemije ME00145B (me)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US26464501P 2001-01-26 2001-01-26
EP02709050A EP1355644B1 (en) 2001-01-26 2002-01-25 The use of substituted azetidinone compounds for the treatment of sitosterolemia
PCT/US2002/001195 WO2002058696A2 (en) 2001-01-26 2002-01-25 The use of substituted azetidinone compounds for the treatment of sitosterolemia

Publications (2)

Publication Number Publication Date
MEP26808A MEP26808A (en) 2010-06-10
ME00145B true ME00145B (me) 2010-10-10

Family

ID=23006987

Family Applications (1)

Application Number Title Priority Date Filing Date
MEP-2008-268A ME00145B (me) 2001-01-26 2002-01-25 Upotreba supstituisanih jedinjenja azetidinona za lečenje sitosterolemije

Country Status (33)

Country Link
US (2) US7417039B2 (me)
EP (1) EP1355644B1 (me)
JP (2) JP4711600B2 (me)
KR (2) KR100820983B1 (me)
CN (1) CN100522159C (me)
AR (1) AR035533A1 (me)
AT (1) ATE331512T1 (me)
AU (1) AU2002243557B2 (me)
BR (1) BRPI0206641B8 (me)
CA (1) CA2434430A1 (me)
CY (1) CY1106149T1 (me)
CZ (1) CZ305202B6 (me)
DE (1) DE60212801T2 (me)
DK (1) DK1355644T3 (me)
ES (1) ES2266459T3 (me)
HK (1) HK1055679A1 (me)
HU (1) HU230435B1 (me)
IL (2) IL156422A0 (me)
ME (1) ME00145B (me)
MX (1) MXPA03006729A (me)
MY (1) MY138301A (me)
NO (1) NO333695B1 (me)
NZ (1) NZ526532A (me)
PE (1) PE20020850A1 (me)
PL (1) PL205343B1 (me)
PT (1) PT1355644E (me)
RS (1) RS50406B (me)
RU (2) RU2756946C2 (me)
SI (1) SI1355644T1 (me)
SK (1) SK287746B6 (me)
TW (1) TWI337076B (me)
WO (1) WO2002058696A2 (me)
ZA (1) ZA200305691B (me)

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CN110520124A (zh) 2017-02-16 2019-11-29 艾尼纳制药公司 用于治疗原发性胆汁性胆管炎的化合物和方法

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